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Incurin Tablets

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What are Incurin Tablets?

Incurin Tablets are an effective treatment for the control of estrogen-responsive urinary incontinence in dogs that have undergone surgical removal of the ovaries and uterus (ovariohysterectomy). This medication has been used effectively worldwide for more than 12 years. Incurin Tablets require a prescription from your veterinarian.

For:

Female Dogs

Benefits:
  • Proven effective in reducing or eliminating urinary incontinence
  • Convenient, once-a-day dosing
  • One simple starting dose for all female dogs, regardless of weight or age
  • Can be titrated to the lowest effective dose
How it works:

Incurin Tablets contain the active ingredient estriol, a natural estrogen, which increases the resting muscle tone of the urethra in female dogs and can be used in the treatment of urinary incontinence due to estrogen depletion. It is given once a day with a starting dose of two tablets for any female dog, regardless of age or weight. The dose of Incurin Tablets is then titrated down over time to the lowest effective dose.

Cautions:

Not for use in humans. Keep this and all drugs out of reach of children and pets. Incurin Tablets are only for use in female dogs that have had surgical removal of the ovaries and uterus. The safety and effectiveness of Incurin Tablets have not been evaluated in dogs less than 1 year of age, intact female dogs, male dogs, dogs used for breeding, or lactating dogs.

Brand Name

Incurin Tablets

Generic Name

Estriol

Manufacturer:

Merck

What is this medication used for:

Incurin Tablets are used for the treatment and control of urinary incontinence that is estrogen-responsive for female dogs that have undergone ovariohysterectomy (surgical removal of the ovaries and uterus).

Availability:

Incurin Tablets are available as tablets and require a prescription from your veterinarian.

How this medicine should be used:

The dose of Incurin Tablets is not body weight-dependent; all dogs receive an initial dose of 2 tablets orally once per day for a minimum of 14 days. After control of urinary incontinence has been achieved, the lowest effective daily dose should be determined by decreasing the dose in a step-wise manner from 2 tablets, to 1 tablet, then a 1/2 tablet depending on your dog's response. There should be a minimum of 7 days between each dose adjustment. When the lowest dose that controls urinary incontinence is identified, the dose may be decreased further by administering once every two days.

What are the side effects:

The most common side effects associated with Incurin Tablets treatment under field conditions included loss of appetite, vomiting, excessive water drinking, and swollen vulva.

What special precautions are there:

The safety and effectiveness of Incurin Tablets have not been evaluated in dogs less than 1 year of age, intact female dogs, male dogs, dogs used for breeding, or lactating dogs. Incurin Tablets are contraindicated in dogs showing polyuria (production of excessive amounts of urine) secondary to polydipsia (excessive thirst), or in pregnant dogs.

In the event of an overdose:

Contact your veterinarian immediately.

How should I store this medication:

Store at or below 77 °F (25°C) with excursions permitted up to 104°F (40°C).

How to Use
Directions:
  • All dogs should receive an initial dose of 2 mg Incurin Tablets (2 tablets) orally once per day for a minimum of 14 days.
  • After urinary incontinence is controlled, the lowest effective daily dose of Incurin Tablets should be determined by decreasing the dose in a step-wise manner from 2 mg once daily (2 tablets) to 1 mg once daily (1 tablet), then 0.5 mg once daily (1/2 tablet) depending upon the response of your individual dog.
  • There should be a minimum of 7 days between each dose adjustment. After the lowest daily dose that controls urinary incontinence is identified, the dose may be decreased further by administering once every two days.
Tip:

Dogs should not receive more than 2 mg Incurin per day (2 tablets). If the dog does not respond to 2 mg of Incurin per day, the diagnosis should be re-assessed.

Cats:
Do not use!
Horses:
Do not use!
Storage:

Store at or below 77°F (25°C) with excursions permitted up to 104°F (40°C).

Ingredients
Incurin Tablets:
Active Ingredients (per tablet)
Strength
Estriol
1 mg
Customer Reviews
Incurin Tablets is rated 5.0 out of 5 by 1.
Rated 5 out of 5 by from Works wonderfully I've been using this with my 2year old Doberman for a few months now. We find a daily pill easiest to remember but she can go two days I between does without any leakage.
Date published: 2016-11-13
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Q&A

Can incurin be used at the same time with DES?

Asked by: Bobby
Since both these medications mimic the effects of estrogen, I would not use these two together unless advised by your veterinarian.
Answered by: Ben B
Date published: 2017-03-01

It's been quite a while since you had them in stock and my sibierian husky needs them periodically. Please get them in stock.  Is there a way you can alert your customers when they come in??  Could you please get an ETA when they should be in stock?? 

Asked by: Patty
Sorry but we currently do not have an ETA on this medication. You may call us or check our website to determine if we have the medication in stock.
Answered by: S Duesler PharmD MBA
Date published: 2016-12-30

My dog takes these because she needs the estrogen.  Without them she is very aggressive (will fight unprovoked) towards dogs and items, is extremely over protective of me, terrified if I leave 15 min (looses incontinence and bowels).  What else can I use?

Asked by: AussieLover
We carry a compounded drug called DES or diethylstilbestrol. It is available in a liquid or capsule and is used to treat urinary incontinence in spayed female dogs. It mimics the effects of the natural female hormone, estrogen. We also carry a drug called Proin which is available in a chewable tablet. It contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage. Your veterinarian will determine the appropriate alternative for your pet's condition.
Answered by: Lisa M
Date published: 2016-11-21

When will this item be back in stock?

Asked by: Dingoears
We do not have an ETA, you may contact our sales department at a later date to determine if we have the product in stock.
Answered by: S Duesler PharmD MBA
Date published: 2016-11-18

Why have these been out of stock for so long? When will you have them in stock?

Asked by: Lindsay
Manufacture backorder. I'm trying the homeopathic drops they have here, proin isn't working for my Doberman.
Answered by: Sandra G
Date published: 2016-11-12

Please bring these back in stock. Is it possible to sign up for an email notification when they are back in stock? Any idea when that might be?

Asked by: beckylee99
Incurin is on backorder by the manufacturer and there is no release date. Please contact us periodically to check availability.
Answered by: Lisa M
Date published: 2016-11-10

Do you have to have a prescription?

Asked by: Mike
Incurin requires a prescription from your veterinarian.
Answered by: paulpharmacistintern
Date published: 2016-10-04
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