Apoquel Chewable (oclacitinib chewable tablet) - Allergy Itch Relief Chewable Tablets for Dogs

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Split Shipment Info

Your order may arrive in two packages. We ship non-Rx items without delay while the Rx approval is pending. You will receive two tracking numbers.

About this product

What is Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Apoquel is a prescription medication that treats and controls itching and inflammation in dogs caused by allergic conditions such as flea allergy, food allergy, contact allergy, and atopic dermatitis. It provides fast relief, with onset of action within 4 hours and effective itch control within 24 hours. Chewable tablets are designed for improved palatability, making dosing easier for dogs that resist traditional pills. Apoquel requires a prescription from your veterinarian and is sold per cheawble tablet in multiple strengths, including 3.6 mg, 5.4 mg, and 16 mg.

Suitable For:

  • Dogs (Over 12 months old and 6.6 lbs, with Itching & Inflammation from Allergies)

Benefits:

  • Begins working within 4 hours and effectively controls itching within 24 hours to stop your dog from scratching, licking, and chewing quickly!
  • Safe for short term and long term usage in dogs 12 months and older.
  • Can be used along with many other common medications, including parasiticides, antibiotics, vaccines, NSAIDs, and other allergen-specific immunotherapy (allergy shots or drops).
  • Not a steroid, antihistamine, or cyclosporine — targets itch at its source with minimal impact on immune function.
  • Controls pruritus associated with allergic dermatitis and atopic dermatitis.
  • Chewable tablet is available in a tasty, pork-liver flavor that makes for easy dosing.

How does Apoquel (oclacitinib chewable tablet) Chewable for Dogs work?

Apoquel is a selective janus kinase (JAK) inhibitor, which targets pruritogenic (itch creating) cytokines. It effectively controls itching due to food allergies, flea allergies, contact dermatitis, and atopic dermatitis. Apoquel works to control pruritus for fast-acting relief, and provides significant short-term and long-term reduction of itching and inflammation.

Cautions:

IMPORTANT SAFETY INFORMATION: Do not use Apoquel or Apoquel Chewable (oclacitinib) Tablets for Dogs in dogs less than 12 months of age or in dogs with skin infections. Apoquel Chewable (oclacitinib) Tablets for Dogs may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. Clinical studies and post-approval evaluations identified both benign and malignant neoplastic conditions. Apoquel Chewable (oclacitinib) Tablets for Dogss have not been evaluated for use alongside certain medications, including those frequently prescribed for skin conditions (like corticosteroids and cyclosporine.) Avoid using in dogs that are breeding, pregnant, or nursing. Common side effects include vomiting and diarrhea. Apoquel Chewable (oclacitinib) Tablets for Dogss can be used safely alongside many common medications such as including parasiticides, antibiotics, topical products for bacterial skin infections, and vaccines.

Brand Name

Apoquel

Generic Name

oclacitinib (ah-clas-eh-tee-nib)

Manufacturer:

Zoetis

What is the most important thing I should know about Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Apoquel Chewable (oclacitinib) Tablets for Dogs is used to relieve itching and inflammation caused by a variety of diagnoses, including allergic dermatitis and atopic dermatitis.

What should I discuss with my veterinarian before giving Apoquel (oclacitinib chewable tablet) Chewable for Dogs to my pet?

Tell your veterinarian if your pet has ever had an allergic reaction to the medication, or if your pet has any allergies to pork.

How should Apoquel (oclacitinib chewable tablet) Chewable for Dogs be given?

The dose of Apoquel Chewable (oclacitinib) Tablets for Dogss is 0.18 to 0.27 mg/lb of body weight. See Apoquel Chewable (oclacitinib) Tablets for Dogs Dosage Chart.

What are the potential side effects of Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Apoquel Chewable (oclacitinib) Tablets for Dogs may increase susceptibility to infection, including demodicosis. It may also exacerbate neoplastic conditions. Adverse reactions reported in a masked field study included diarrhea, vomiting, anorexia, new cutaneous or subcutaneous lumps, profuse salivation, and lethargy. In most cases, diarrhea, vomiting, anorexia, and lethargy spontaneously resolved with continued dosing. Contact your veterinarian if you see abnormal skin changes, dermal lumps, or growths after your dog has consumed Apoquel.

What happens if I miss giving a dose of Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Give the missed dose with food as soon as you remember and resume a regular dosing schedule.

What happens if I overdose my pet on Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Contact your veterinarian immediately for medical attention, or visit your closest emergency animal hospital..

What should I avoid while giving Apoquel (oclacitinib chewable tablet) Chewable for Dogs to my pet?

Apoquel Chewable (oclacitinib) Tablets for Dogs should not be given to dogs younger than 12 months or those with serious infections. Apoquel Chewable (oclacitinib) Tablets for Dogs should not be used in breeding, pregnant or lactating dogs. Apoquel Chewable (oclacitinib) Tablets for Dogs usage has not been evaluated in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents. Dogs taking Apoquel Chewable (oclacitinib) Tablets for Dogss should be monitored for any developing harmful side effects and infections, including demodicosis and neoplasia.

What other drugs will affect Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Talk to your veterinarian before giving any prescription or over the counter medications.

See more

Apoquel Chewable (oclacitinib) Tablets for Dogs Directions:

  • Administer to your dog orally in convenient twice-daily doses for up to 14 days according to the weight chart below, then administered once daily for a maintenance dose.
Tip:

Apoquel Chewable (oclacitinib) Tablets for Dogs may be administered with or without food

Apoquel Chewable (oclacitinib) Tablets for Dogs Dosage Chart:

Apoquel Chewable (oclacitinib) Tablets for Dogs Initial Dosage for Dogs: (over 12 months of age)
Weight Amount
6.6-9.9 lbs 1/2 of a 3.6 mg chewable tablet twice daily for up to 14 days
10-14.9 lbs 1/2 of a 5.4 mg chewable tablet twice daily for up to 14 days
15-19.9 lbs One 3.6 mg chewable tablet twice daily for up to 14 days
20-29.9 lbs One 5.4 mg chewable tablet twice daily for up to 14 days
30-44.9 lbs 1/2 of a 16 mg chewable tablet twice daily for up to 14 days
45-59.9 lbs Two 5.4 mg chewable tablets twice daily for up to 14 days
60-89.9 lbs One 16 mg table twice daily for up to 14 days
90-129.9 lbs 1 1/2 16 mg chewable tablets twice daily for up to 14 days
130-175.9 lbs Two 16 mg chewable tablets twice daily for up to 14 days
Apoquel Chewable (oclacitinib) Tablets for Dogs Maintenance Dosage for Dogs: (over 12 months of age)
Weight Amount
6.6-9.9 lbs 1/2 of a 3.6 mg chewable tablet once daily
10-14.9 lbs 1/2 of a 5.4 mg chewable tablet once daily
15-19.9 lbs One 3.6 mg chewable tablet once daily
20-29.9 lbs One 5.4 mg chewable tablet once daily
30-44.9 lbs 1/2 of a 16 mg chewable tablet once daily
45-59.9 lbs Two 5.4 mg chewable tablets once daily
60-89.9 lbs One 16 mg table once daily
90-129.9 lbs 1 1/216 mg chewable tablets once daily
130-175.9 lbs Two 16 mg chewable tablets once daily
Apoquel Chewable (oclacitinib) Tablets for Dogs Dosage for Cats:
Cats
Do not use!
Apoquel Chewable (oclacitinib) Tablets for Dogs Dosage for Horses:
Horses
Do not use!

Ingredients in Apoquel Chewable (oclacitinib) Tablets for Dogs Tablets:

Apoquel 3.6 mg chewable tablet
Active Ingredient Amount
Oclacitinib maleate 3.6 mg
Apoquel 5.4 mg chewable tablet
Active Ingredient Amount
Oclacitinib maleate 5.4 mg
Apoquel 16 mg chewable tablet
Active Ingredient Amount
Oclacitinib maleate 16 mg
Product Details
plus minus

What is Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Apoquel is a prescription medication that treats and controls itching and inflammation in dogs caused by allergic conditions such as flea allergy, food allergy, contact allergy, and atopic dermatitis. It provides fast relief, with onset of action within 4 hours and effective itch control within 24 hours. Chewable tablets are designed for improved palatability, making dosing easier for dogs that resist traditional pills. Apoquel requires a prescription from your veterinarian and is sold per cheawble tablet in multiple strengths, including 3.6 mg, 5.4 mg, and 16 mg.

Suitable For:

  • Dogs (Over 12 months old and 6.6 lbs, with Itching & Inflammation from Allergies)

Benefits:

  • Begins working within 4 hours and effectively controls itching within 24 hours to stop your dog from scratching, licking, and chewing quickly!
  • Safe for short term and long term usage in dogs 12 months and older.
  • Can be used along with many other common medications, including parasiticides, antibiotics, vaccines, NSAIDs, and other allergen-specific immunotherapy (allergy shots or drops).
  • Not a steroid, antihistamine, or cyclosporine — targets itch at its source with minimal impact on immune function.
  • Controls pruritus associated with allergic dermatitis and atopic dermatitis.
  • Chewable tablet is available in a tasty, pork-liver flavor that makes for easy dosing.

How does Apoquel (oclacitinib chewable tablet) Chewable for Dogs work?

Apoquel is a selective janus kinase (JAK) inhibitor, which targets pruritogenic (itch creating) cytokines. It effectively controls itching due to food allergies, flea allergies, contact dermatitis, and atopic dermatitis. Apoquel works to control pruritus for fast-acting relief, and provides significant short-term and long-term reduction of itching and inflammation.

Cautions:

IMPORTANT SAFETY INFORMATION: Do not use Apoquel or Apoquel Chewable (oclacitinib) Tablets for Dogs in dogs less than 12 months of age or in dogs with skin infections. Apoquel Chewable (oclacitinib) Tablets for Dogs may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. Clinical studies and post-approval evaluations identified both benign and malignant neoplastic conditions. Apoquel Chewable (oclacitinib) Tablets for Dogss have not been evaluated for use alongside certain medications, including those frequently prescribed for skin conditions (like corticosteroids and cyclosporine.) Avoid using in dogs that are breeding, pregnant, or nursing. Common side effects include vomiting and diarrhea. Apoquel Chewable (oclacitinib) Tablets for Dogss can be used safely alongside many common medications such as including parasiticides, antibiotics, topical products for bacterial skin infections, and vaccines.

Brand Name

Apoquel

Generic Name

oclacitinib (ah-clas-eh-tee-nib)

Manufacturer:

Zoetis

What is the most important thing I should know about Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Apoquel Chewable (oclacitinib) Tablets for Dogs is used to relieve itching and inflammation caused by a variety of diagnoses, including allergic dermatitis and atopic dermatitis.

What should I discuss with my veterinarian before giving Apoquel (oclacitinib chewable tablet) Chewable for Dogs to my pet?

Tell your veterinarian if your pet has ever had an allergic reaction to the medication, or if your pet has any allergies to pork.

How should Apoquel (oclacitinib chewable tablet) Chewable for Dogs be given?

The dose of Apoquel Chewable (oclacitinib) Tablets for Dogss is 0.18 to 0.27 mg/lb of body weight. See Apoquel Chewable (oclacitinib) Tablets for Dogs Dosage Chart.

What are the potential side effects of Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Apoquel Chewable (oclacitinib) Tablets for Dogs may increase susceptibility to infection, including demodicosis. It may also exacerbate neoplastic conditions. Adverse reactions reported in a masked field study included diarrhea, vomiting, anorexia, new cutaneous or subcutaneous lumps, profuse salivation, and lethargy. In most cases, diarrhea, vomiting, anorexia, and lethargy spontaneously resolved with continued dosing. Contact your veterinarian if you see abnormal skin changes, dermal lumps, or growths after your dog has consumed Apoquel.

What happens if I miss giving a dose of Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Give the missed dose with food as soon as you remember and resume a regular dosing schedule.

What happens if I overdose my pet on Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Contact your veterinarian immediately for medical attention, or visit your closest emergency animal hospital..

What should I avoid while giving Apoquel (oclacitinib chewable tablet) Chewable for Dogs to my pet?

Apoquel Chewable (oclacitinib) Tablets for Dogs should not be given to dogs younger than 12 months or those with serious infections. Apoquel Chewable (oclacitinib) Tablets for Dogs should not be used in breeding, pregnant or lactating dogs. Apoquel Chewable (oclacitinib) Tablets for Dogs usage has not been evaluated in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents. Dogs taking Apoquel Chewable (oclacitinib) Tablets for Dogss should be monitored for any developing harmful side effects and infections, including demodicosis and neoplasia.

What other drugs will affect Apoquel (oclacitinib chewable tablet) Chewable for Dogs?

Talk to your veterinarian before giving any prescription or over the counter medications.

See more
How to use
plus minus

Apoquel Chewable (oclacitinib) Tablets for Dogs Directions:

  • Administer to your dog orally in convenient twice-daily doses for up to 14 days according to the weight chart below, then administered once daily for a maintenance dose.
Tip:

Apoquel Chewable (oclacitinib) Tablets for Dogs may be administered with or without food

Apoquel Chewable (oclacitinib) Tablets for Dogs Dosage Chart:

Apoquel Chewable (oclacitinib) Tablets for Dogs Initial Dosage for Dogs: (over 12 months of age)
Weight Amount
6.6-9.9 lbs 1/2 of a 3.6 mg chewable tablet twice daily for up to 14 days
10-14.9 lbs 1/2 of a 5.4 mg chewable tablet twice daily for up to 14 days
15-19.9 lbs One 3.6 mg chewable tablet twice daily for up to 14 days
20-29.9 lbs One 5.4 mg chewable tablet twice daily for up to 14 days
30-44.9 lbs 1/2 of a 16 mg chewable tablet twice daily for up to 14 days
45-59.9 lbs Two 5.4 mg chewable tablets twice daily for up to 14 days
60-89.9 lbs One 16 mg table twice daily for up to 14 days
90-129.9 lbs 1 1/2 16 mg chewable tablets twice daily for up to 14 days
130-175.9 lbs Two 16 mg chewable tablets twice daily for up to 14 days
Apoquel Chewable (oclacitinib) Tablets for Dogs Maintenance Dosage for Dogs: (over 12 months of age)
Weight Amount
6.6-9.9 lbs 1/2 of a 3.6 mg chewable tablet once daily
10-14.9 lbs 1/2 of a 5.4 mg chewable tablet once daily
15-19.9 lbs One 3.6 mg chewable tablet once daily
20-29.9 lbs One 5.4 mg chewable tablet once daily
30-44.9 lbs 1/2 of a 16 mg chewable tablet once daily
45-59.9 lbs Two 5.4 mg chewable tablets once daily
60-89.9 lbs One 16 mg table once daily
90-129.9 lbs 1 1/216 mg chewable tablets once daily
130-175.9 lbs Two 16 mg chewable tablets once daily
Apoquel Chewable (oclacitinib) Tablets for Dogs Dosage for Cats:
Cats
Do not use!
Apoquel Chewable (oclacitinib) Tablets for Dogs Dosage for Horses:
Horses
Do not use!
Ingredients
plus minus

Ingredients in Apoquel Chewable (oclacitinib) Tablets for Dogs Tablets:

Apoquel 3.6 mg chewable tablet
Active Ingredient Amount
Oclacitinib maleate 3.6 mg
Apoquel 5.4 mg chewable tablet
Active Ingredient Amount
Oclacitinib maleate 5.4 mg
Apoquel 16 mg chewable tablet
Active Ingredient Amount
Oclacitinib maleate 16 mg
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Why Does Apoquel
Lead The Pack?

Apoquel works at the underlying cause of itch to provide relief fast.

  • bullet points icon

    Antihistamines offer little or no benefit in treating flare-ups in a majority of dogs with allergic itch.6

  • bullet points icon

    Steroid based treatments may offer relief but may not be a good option if your dog requires long-term treatment.

  • bullet points icon

    Home remedies, such as, topicals, may provide some temporary relief but don’t treat the underlying cause of allergic itch.

product image

 

IMPORTANT SAFETY INFORMATION

Do not use Apoquel or Apoquel Chewable in dogs less than 12 months of age or those with serious infections. Apoquel and Apoquel Chewable may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel and Apoquel Chewable have not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel and Apoquel Chewable have been used safely with many common medications including parasiticides, antibiotics and vaccines. See full Prescribing Information at ApoquelPI.com and ApoquelChewablePI.com.

REFERENCES
  1.  Data on file, PetTrak Total Unique Patient Count, December 2022, Zoetis Inc. (TI-09437).
  2. Data on file: Study Report A161C-US-21-C02, Zoetis Inc., 2022 (TI-09898).
  3. Cosgrove SB, Cleaver DM, King VL, et al. Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Vet Dermatol. 2015;26(3):171-179, e35. doi: 10.1111/vde.12194 (AR-01949).
  4. Data on file: Study Report A461N-US-21-B66, Zoetis Inc. 2022.
  5. FOI Apoquel Chewable FOI Summary: 2023/06/09 Original NADA 141-555 (v2.0).
  6. Gonzales AJ, Bowman JW, Fici GJ, et al. Oclacitinib (APOQUEL) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. J Vet Pharmacol Therapy. 2014;37(4)317-24. doi:10.1111/jvp.12101 (AR-00542).
  7. Data on file, Apoquel Cytopoint Vet Tracker Wave 11 (December 20 2018) (TI-04447).
  8. Data on file, APOQUEL/CYTOPOINT Pet Owner Tracker Wave 11, 2022, Zoetis Inc. (TI-08418).
  9. Data on file. A Five-Year Post-Approval Safety Review for Apoquel® in the US (May 2013 to August 2018), Zoetis Inc (TI-04506).
  10. Volume 6C Summary of the Product Characteristics: SPC European Commission, Brussels. 1 Vol. 6C. July 10, 2006, 1-11. (AR-08728).
  11. Olivry T, DeBoer DJ, Favrot C, et al. for the International Committee on Allergic Diseases of Animals. Treatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA). BMC Vet Res. 2015;11:210. doi: 10.1186/s12917-015-0514-6.