Diphenhydramine (Generic Benadryl)

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About this product

What is Diphenhydramine (Generic Benadryl)?

Diphenhydramine is an antihistamine used to relieve allergy symptoms, insect stings, motion sickness, travel anxiety, and other conditions.

For:

Cats and Dogs

Benefits:

  • Effectively relieves allergy symptoms and itching caused by insect bites
  • Can be used as a sedative to treat motion sickness or travel anxiety
  • Relieves coughing

How does Diphenhydramine (Generic Benadryl) work?

Diphenhydramine comes in 25 mg minitabs or 50 mg capsules, and is a generic version of Benadryl. As an antihistamine, it counteracts the effect of histamine, which causes symptoms like itching and sneezing.

Cautions:

This medication should not be used in pregnant or nursing animals. Do not use the diphenhydramine available in combination with sinus or cold medicines in your pet.

Brand Name:

Benadryl (Warner Lambert), Histacalm (Virbac)

Generic Name:

Diphenhydramine (dye-fen-hy'-dra-meen)

Manufacturer:

Various

What is the most important thing I should know about Diphenhydramine (Generic Benadryl)?

Diphenhydramine is an antihistamine used to relieve allergy symptoms, insect bites or stings and other causes of itching. It is also used for its sedative and antiemetic effects in the treatment of motion sickness and travel anxiety. It is also used for its antitussive effect. Diphenhydramine is a non-prescription (OTC) product available as 25 mg minitabs and 50 mg capsules.

What should I discuss with my veterinarian before giving Diphenhydramine (Generic Benadryl) to my pet?

Tell your veterinarian if your pet is allergic to diphenhydramine or other antihistamines. Also tell your veterinarian if your pet is pregnant or lactating, or has history of glaucoma, prostate disease, urinary obstruction, or high blood pressure. Always tell your veterinarian and pharmacist what other medications your pet is taking.

How should Diphenhydramine (Generic Benadryl) be given?

Oral diphenhydramine is not FDA-approved for use in veterinary medicine; however, it is a commonly accepted practice to use this medication in dogs and cats. The usual dose in dogs and cats is 0.5-2 mg/lb every 8-12 hours. The slow release capsule should not be mixed or dissolved in food.

What are the potential side effects of Diphenhydramine (Generic Benadryl)?

Side effects of diphenhydramine include drowsiness, dry mouth and urinary retention. Rarely, vomiting and diarrhea can occur.

What happens if I miss giving a dose of Diphenhydramine (Generic Benadryl)?

Give the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

What happens if I overdose my pet on Diphenhydramine (Generic Benadryl)?

Contact your veterinarian or veterinary emergency room. Symptoms of overdose can include seizures, extreme drowsiness, coma, respiratory depression, and death.

What should I avoid while giving Diphenhydramine (Generic Benadryl) to my pet?

Do not give other sinus or cold medicines containing diphenhydramine to your pet while giving Diphenhydramine (Generic Benadryl).

What other drugs will affect Diphenhydramine (Generic Benadryl)?

Use with caution when given with other CNS (central nervous system)-depressant drugs such as tranquilizers or barbiturates.

See more

Diphenhydramine (Generic Benadryl) Directions:

  • Diphenhydramine is an antihistamine used to relieve allergy symptoms, insect stings, motion sickness, travel anxiety and other conditions.
  • It is available over-the-counter (OTC) as 25 mg tablets and 50 mg capsules.
  • Diphenhydramine should not be used in dogs or cats that are pregnant or nursing.
Tip:

The slow release capsule should NOT be mixed or dissolved in food. Do not use sinus or cold medications containing diphenhydramine in your pet.

Diphenhydramine (Generic Benadryl) Dosage:

Diphenhydramine (Generic Benadryl) Dosage for Cats
Weight Dosage
All weights Give 0.5-2 mg/lb of pet's body weight every 8-12 hours
Diphenhydramine (Generic Benadryl) Dosage for Dogs
Weight Dosage
All weights Give 0.5-2 mg/lb of pet's body weight every 8-12 hours
Diphenhydramine (Generic Benadryl) Dosage for Horses
Horses
Do not use!

Storage:

Store this medication at room temperature, away from excess heat, light and moisture. Keep this medication in the container it came in, tightly closed. Store this medication at room temperature, away from excess heat, light, and moisture. Do not store in the bathroom. Throw away any medication that is outdated or no longer needed. Keep medication away from children and pets.

Diphenhydramine (Generic Benadryl) Ingredients:

Diphenhydramine HCl 25 mg Minitabs
Active Ingredients (per minitab) Amount
Diphenhydramine Hydrochloride 25 mg
Other Ingredients: Corn starch, D&C red #27, Dicalcium Phosphate, Magnesium Stearate, Microcrystalline Cellulose, Polyethylene Glycol, Polyvinyl Alcohol, Silicon Dioxide, Stearic Acid, Talc, Titanium Dioxide.
Diphenhydramine HCl 50 mg Capsules
Active Ingredients (per capsule) Amount
Diphenhydramine Hydrochloride 50 mg
Other Ingredients: Colloidal Silicon Dioxide, Croscarmellose Sodium, D&C Red #28, FD&C Blue #1, FD&C Red #3, FD&C Red #40, Gelatin, Lactose, Magnesium Stearate. May also contain Polysorbate 80 and iron oxide.
Product Details
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What is Diphenhydramine (Generic Benadryl)?

Diphenhydramine is an antihistamine used to relieve allergy symptoms, insect stings, motion sickness, travel anxiety, and other conditions.

For:

Cats and Dogs

Benefits:

  • Effectively relieves allergy symptoms and itching caused by insect bites
  • Can be used as a sedative to treat motion sickness or travel anxiety
  • Relieves coughing

How does Diphenhydramine (Generic Benadryl) work?

Diphenhydramine comes in 25 mg minitabs or 50 mg capsules, and is a generic version of Benadryl. As an antihistamine, it counteracts the effect of histamine, which causes symptoms like itching and sneezing.

Cautions:

This medication should not be used in pregnant or nursing animals. Do not use the diphenhydramine available in combination with sinus or cold medicines in your pet.

Brand Name:

Benadryl (Warner Lambert), Histacalm (Virbac)

Generic Name:

Diphenhydramine (dye-fen-hy'-dra-meen)

Manufacturer:

Various

What is the most important thing I should know about Diphenhydramine (Generic Benadryl)?

Diphenhydramine is an antihistamine used to relieve allergy symptoms, insect bites or stings and other causes of itching. It is also used for its sedative and antiemetic effects in the treatment of motion sickness and travel anxiety. It is also used for its antitussive effect. Diphenhydramine is a non-prescription (OTC) product available as 25 mg minitabs and 50 mg capsules.

What should I discuss with my veterinarian before giving Diphenhydramine (Generic Benadryl) to my pet?

Tell your veterinarian if your pet is allergic to diphenhydramine or other antihistamines. Also tell your veterinarian if your pet is pregnant or lactating, or has history of glaucoma, prostate disease, urinary obstruction, or high blood pressure. Always tell your veterinarian and pharmacist what other medications your pet is taking.

How should Diphenhydramine (Generic Benadryl) be given?

Oral diphenhydramine is not FDA-approved for use in veterinary medicine; however, it is a commonly accepted practice to use this medication in dogs and cats. The usual dose in dogs and cats is 0.5-2 mg/lb every 8-12 hours. The slow release capsule should not be mixed or dissolved in food.

What are the potential side effects of Diphenhydramine (Generic Benadryl)?

Side effects of diphenhydramine include drowsiness, dry mouth and urinary retention. Rarely, vomiting and diarrhea can occur.

What happens if I miss giving a dose of Diphenhydramine (Generic Benadryl)?

Give the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

What happens if I overdose my pet on Diphenhydramine (Generic Benadryl)?

Contact your veterinarian or veterinary emergency room. Symptoms of overdose can include seizures, extreme drowsiness, coma, respiratory depression, and death.

What should I avoid while giving Diphenhydramine (Generic Benadryl) to my pet?

Do not give other sinus or cold medicines containing diphenhydramine to your pet while giving Diphenhydramine (Generic Benadryl).

What other drugs will affect Diphenhydramine (Generic Benadryl)?

Use with caution when given with other CNS (central nervous system)-depressant drugs such as tranquilizers or barbiturates.

See more
How to use
plus minus

Diphenhydramine (Generic Benadryl) Directions:

  • Diphenhydramine is an antihistamine used to relieve allergy symptoms, insect stings, motion sickness, travel anxiety and other conditions.
  • It is available over-the-counter (OTC) as 25 mg tablets and 50 mg capsules.
  • Diphenhydramine should not be used in dogs or cats that are pregnant or nursing.
Tip:

The slow release capsule should NOT be mixed or dissolved in food. Do not use sinus or cold medications containing diphenhydramine in your pet.

Diphenhydramine (Generic Benadryl) Dosage:

Diphenhydramine (Generic Benadryl) Dosage for Cats
Weight Dosage
All weights Give 0.5-2 mg/lb of pet's body weight every 8-12 hours
Diphenhydramine (Generic Benadryl) Dosage for Dogs
Weight Dosage
All weights Give 0.5-2 mg/lb of pet's body weight every 8-12 hours
Diphenhydramine (Generic Benadryl) Dosage for Horses
Horses
Do not use!

Storage:

Store this medication at room temperature, away from excess heat, light and moisture. Keep this medication in the container it came in, tightly closed. Store this medication at room temperature, away from excess heat, light, and moisture. Do not store in the bathroom. Throw away any medication that is outdated or no longer needed. Keep medication away from children and pets.

Ingredients
plus minus

Diphenhydramine (Generic Benadryl) Ingredients:

Diphenhydramine HCl 25 mg Minitabs
Active Ingredients (per minitab) Amount
Diphenhydramine Hydrochloride 25 mg
Other Ingredients: Corn starch, D&C red #27, Dicalcium Phosphate, Magnesium Stearate, Microcrystalline Cellulose, Polyethylene Glycol, Polyvinyl Alcohol, Silicon Dioxide, Stearic Acid, Talc, Titanium Dioxide.
Diphenhydramine HCl 50 mg Capsules
Active Ingredients (per capsule) Amount
Diphenhydramine Hydrochloride 50 mg
Other Ingredients: Colloidal Silicon Dioxide, Croscarmellose Sodium, D&C Red #28, FD&C Blue #1, FD&C Red #3, FD&C Red #40, Gelatin, Lactose, Magnesium Stearate. May also contain Polysorbate 80 and iron oxide.
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Based on 67 reviews
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Jackson
11 months ago
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Breed Boxer
It has really helped with my dogs allergies.
Helpful?
paragrap73
1 year ago
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Breed American Pit Bull Terrier
Second Time purchasing Benadryl for my dog. It appears to be working and hope it continues to help my dog with mass cell lesions.
Helpful?
JJones
2 years ago
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Breed pitbull
good value
my older dog needs to be on this along with this arthritis medicine. the packs at the store dont have nearly enough for his use. This is a large quantity and works just the same. The only thing I found was that I need three of the lower dose because the higher dose is a capsule and my dog kept breaking it apart and then obviously NOT wanting to eat the powder. so if this is something you have to give your dog regularly, with other pills like I do, then I would suggest the smaller dose and just doing multiple. Saves the headache of the broken capsule.
Helpful?
priss0529
4 years ago
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Breed Mixed
Perfect Experience
I got my product VERY quick and was able to purchase them for a great price because the discount code from petmed that I was given and to top it all off when I got my package there was a HUGE dog treat inside both by dogs appreciated it very much. Thank you PetMed for your amazing services. I will definitely be purchasing items from here again.
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Paul
4 years ago
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Breed German Shepherd
Very Happy
My dog Paul was always licking his belly, inner thigh and scratching. I was bathing him and applying moisturizers to his skin but nothing seemed to him. He's normal short haired as a German Shepherd and only 5 months old. When starting on the Benadryl, that really helped with the itching and he has not been licking or scratching as before.
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Helpful?
canuckgirlinvt
5 years ago
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May help with feline itchiness.
My cat developed an over-grooming problem where she licks her belly and the insides of her back legs. She was always a fussy OCD cat and this developed when she was 11. I think the problem is partly psychogenic, but we tried hypoallergenic food, and prednisone, which worked but I wanted to get her off it. Tried diphenydramine and it does seem to help. 12.5 mg once a day for now. However, it is so bitter that I could not mix it in her food and I didn't want to battle her everyday to get it into her, so I bought size 4 gel caps, put the pill in a gel cap, and covered the gel cap with cream cheese, and she eats it up no problem (and she still likes me!).
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PEACH
5 years ago
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Thumbs up Would recommend this product
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Muppy
6 years ago
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Still too big
I thought the pills would be half the size, kind of the size of a homeopathic tablet. Cat hates taste & won't take it either by subterfuge or chucking it down her throat. If smaller I think I could manage it. She's a clever cat & they probably would work if I could get it in her !!!
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