Comfortis

5 out of 5 Customer Rating
Comfortis is rated 4.6 out of 5 by 1272.
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Starts $138.56 $96.99
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Comfortis

5 out of 5 Customer Rating
Comfortis is rated 4.6 out of 5 by 1272.
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Starts $138.56 $96.99
Most orders ship the same day
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Reviews

Rated 5 out of 5 by from Working great for fleas, not so great for ticks. I'd always thought Comfortus was a flea and tick medication, but apparently the tick side hasn't been proven so the company doesn't make a claim to kill ticks (I just looked at the package and it only says fleas). We found two ticks on our dog in one week (we've never had this problem before, and we've been using Comfortus for 8 years—maybe it's just a bad season this year). Regardless, for us, this product doesn't work for ticks but works excellent for fleas.
Date published: 2020-08-08
Rated 1 out of 5 by from Didn’t last My dog has a problem with flea prevention medications. Topical does not work and chewable shave worked in the past, however I heard not so great things about Bravecto so I switched to this. I gave it to him in June 12 and yesterday (June 29th) I found multiple fleas on him. It’s been less than three weeks. Very disappointed and will not purchase again because it’s so pricey to not even work for a month.
Date published: 2020-07-01
Rated 5 out of 5 by from I love this product. It can be pricey but it's money well spent. If your animal still itches, he may have a skin condition. Antibiotics Will help.
Date published: 2020-06-06
Rated 1 out of 5 by from Causes itchiness this product did in fact get rid of fleas and keep them from coming back. Problem is, now my dog is left with incessant itchiness. I called my vet and apparently this can be a side effect of comfortis. My poor dog. Now the flea itch is gone but she's still itching like she has bugs. Would not buy again. Waste of money. Especially since I had to consult the vet afterwards. Good fir ridding fleas, bad for your furry friends sanity!
Date published: 2020-05-28
Rated 5 out of 5 by from Effective and Safe I have used Comfortus for years and have never seen fleas on the dogs or cats. In addition, none of the pets have ever had an adverse reaction or side effects.
Date published: 2020-05-15
Rated 5 out of 5 by from Wonderful product! After a half hour of taking the medication the fleas died and fell off. Later after going outside I saw another flea dying on her coat and got rid of it. I’m very pleased.
Date published: 2020-05-01
Rated 5 out of 5 by from No more scratching! My Tibetan Terrier was on Frontline, but was scratching so hard that the fur was off his hind legs. At the vet, a flea dropped onto the examining table! Apparently, he is so allergic to flea bites that the Frontline didn't kill the flea fast enough to avoid problems. Comfortis solved his problem on the first dose. Fur grew back! He's been on it for 3 years now, with no problem. HOWEVER - I cut the pill in half, giving half after his food in the morning and the other half at night. That stopped his initial upset stomach from the dose.
Date published: 2020-03-14
Rated 5 out of 5 by from No fleas The pill was easy to give to my 9lb cat because it was fairly small. My 13lb cat was a little struggle and she threw up a few hours after the initial treatment but I think that might of been due to over eating. Cats had eaten kibble for breakfast, 30 min later given flea meds so u feed them wet food after because it says to administer with food. I'll evaluate the next dose with both cats and see what happens. The fleas were killed very quickly and now my cats are happy because they aren't itching anymore. I really like the ease of the oral administration and knowing that there isn't poison on the cats fur that my infant could possibly touxh. Also it's good to know if our little escapee gets out again she won't bring fleas back in the house anymore
Date published: 2020-02-15
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Questions

Will this kill flea eggs that are already on the dog ?

Asked by: Sparky
Thank you for your question. Comfortis does kill existing fleas. It starts killing fleas within 30 minutes. It also kills fleas before they can lay eggs
Answered by: Crystal RPTechnician
Date published: 2020-09-17

My cat has fleas, I don’t have a vet. How can I purchase this?

Asked by: Thor
You will need to find a vet (which your kitty needs anyway for it's rabies vaccination) as Comfortis requires a veterinarian's prescription. You can try an over-the-counter topical flea product such as Frontline or Advantage II.
Answered by: SuzyCVT
Date published: 2020-08-06

I give my dog her comfortis regularly and on time but I’m still finding fleas and she is scratching so much?

Asked by: Shoofly
You may have a situation where fleas are being brought into your dog's environment from elsewhere, such as stray animals or wildlife. Check your property and home for unwelcome furry intruders. Also, depending upon how long your dog has been using Comfortis, you may still have hatching eggs and cocooned larva which are getting on your dog for the first time and being killed by the Comfortis. If the fleas you are seeing are small and not the large adults, this is likely the case. Cocooned larva can survive for up to 2 years in the right environment. Your dog may also be scratching from things other than fleas. Dogs suffer from allergies just like we do but scratch instead of sneeze and get watery eyes. Consult your vet for possible allergy testing or treatment. Apoquel and Cytopoint are 2 excellent options for allergy treatment. Good luck!
Answered by: SuzyCVT
Date published: 2020-06-14

Is there still Comfortis PLUS? If so, safe for cats?

Asked by: SusieQ
Comfortis Plus is called Trifexis in the United States and it is not labeled for use in cats. If you want to protect your cat from fleas, heartworms and other intestinal and external parasites, there are several options, such as Revolution, Revolution Plus, Advantage Multi or if you like Comfortis, you can add a heartworm preventative such as HeartGard for Cats or Interceptor.
Answered by: SuzyCVT
Date published: 2020-06-14

Does this kill ticks

Asked by: TwinkleMom
No, Comfortis is not labeled as killing ticks. However, some people have said that it does help.
Answered by: SuzyCVT
Date published: 2020-07-12

do a need a prescription

Asked by: Tinabina
Yes.
Answered by: Shari PetMed Pro
Date published: 2020-05-13

Vets are not working or only seeing sick dogs. Need flea pills and have no script.????

Asked by: Billy
I called my vet thinking the same thing emergency only but it turns out they do curb side pick up got my dog out of the car examined her and brought her back and okayed my pets script that day.. I also heard this whole time they have been doing grooming. worth the 40 bucks for the visit since 1800 pet meds is so much cheaper
Answered by: chol87
Date published: 2020-05-07

Do you have to have a vet prescription to purchase flea meds

Asked by: Linda
Yes, a prescription from a licensed United States Veterinarian is required to purchase Comfortis® (spinosad). Please consult your veterinarian to discuss if this medication is appropriate for your pet. Thank you.
Answered by: Joshua T
Date published: 2020-04-19
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What is Comfortis (spinosad)?

Comfortis is the first FDA-approved, chewable beef-flavored tablet (derived from pork protein and hydrolyzed soy) that kills fleas and prevents flea infestations on dogs and cats for a full month. Comfortis for Dogs & Cats requires a prescription from your veterinarian.

For:

Dogs & Cats (14 weeks of age or older)

Benefits:

  • Starts killing fleas within 30 minutes
  • Lasts a full month
  • Kills fleas before they can lay eggs
  • Comes in a convenient chewable, beef-flavored tablet
  • Spinosad, the active ingredient in Comfortis, is environmentally friendly

Comfortis is the #1 recommended Rx Flea-only medication for dogs and cats

How does Comfortis work?

The active ingredient in Comfortis (Spinosad) kills fleas by causing excitation of the insect's nervous system, leading to paralysis and rapid death.

Cautions:

Side effects may occur, including vomiting. If your pet is experiencing loss of appetite, lethargy, or any other difference in behavior, contact your veterinarian. The FDA has received reports of adverse reactions in dogs receiving the drug Comfortis (spinosad) concurrently with high, extra-label doses of ivermectin. Dogs receiving extra-label doses of ivermectin to treat non-responsive demodectic mange and other conditions have developed signs of ivermectin toxicity. Ivermectin is an ingredient found in heartworm preventatives such as Heartgard Plus, Heartgard, Iverhart Plus and Ivomec. In cats, the most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin. For complete safety information, see product label.

Brand Name:

Comfortis (Elanco)

Generic Name:

Spinosad

What is the most important information I should know about Comfortis?

Comfortis is a prescription medication FDA approved for use in dogs and puppies and cats and kittens 14 weeks of age or older to kill fleas and prevent flea infestations for one month. Comfortis is available in a Pink box for dogs 5 to 10 lbs and cats 4.1-6 lbs (140 mg), Orange box for dogs 10.1 to 20 lbs and cats 6.1-12 lbs (270 mg), Green box for dogs 20.1 to 40 lbs and cats 12.1-24 (560 mg), Blue box for dogs 40.1 to 60 lbs (810 mg), and Brown box for dogs 60.1 to 120 lbs (1620 mg). Please note: Cats over 24 lbs should be administered the appropriate combination of tablets.

What should I discuss with my veterinarian before giving Comfortis to my pet?

Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog or cat has a history of seizures (epilepsy).

How should Comfortis be given?

Give Comfortis chewable tablets with food. Give Comfortis chewable tablets once a month. Comfortis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose the pet with another full dose. Store Comfortis at room temperature (68-77 F)

Comfortis is an easy-to-give oral treatment that doesn't make a mess

What are the potential side effects of Comfortis?

Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Comfortis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, incoordination, weight loss, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions.Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.

What happens if I miss giving a dose of Comfortis?

Give the missed dose as soon as you remember and resume a monthly dosing schedule.

What happens if I overdose my pet on Comfortis?

Contact your veterinarian immediately.

What should I avoid while giving Comfortis?

Your pet may maintain normal activities and interactions while being given Comfortis. The safe use of Comfortis in breeding, pregnant, or lactating cats and dogs has not been evaluated.

What other drugs will affect Comfortis?

Talk to your veterinarian before giving any prescription or over the counter medications.

Comfortis is trusted by vets and has been prescribed over 90 million times

Comfortis Directions:

  • Comfortis is a prescription medication used in dogs and cats to kill fleas and prevent flea infestations for 1 month.
  • Comfortis chewable tablets are beef flavored.
  • Comfortis can be given to dogs at least 14 weeks of age, weighing at least 5 lbs, and cats 14 weeks of age, weighing at least 4 lbs.
Tip:

If vomiting occurs within 1 hour of administration, redose the pet with another tablet.

Comfortis Dosage for Dogs:

Dogs/Puppies (14 weeks of age or older):
Weight Dosage
5-10 lbs (Pink Box) Give one 140 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
10.1-20 lbs (Orange Box) Give one 270 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
20.1-40 lbs (Green Box) Give one 560 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
40.1-60 lbs (Blue Box)Give one 810 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
60.1-120 lbs (Brown Box)Give one 1620 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
Over 120 lbs Give the appropriate combination of tablets

Comfortis Dosage for Cats:

Cats/Kittens (14 weeks of age or older):
Weight Dosage
4.1-6 lbs (Pink Box) Give one 140 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
6.1-12 lbs (Orange Box) Give one 270 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
12.1-24 lbs (Green Box) Give one 560 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
Over 24 lbs Give the appropriate combination of tablets
Comfortis Dosage for Horses:
Horses
Do not use!
Storage:

Store Comfortis at room temperature (68°-77° F).

Comfortis Ingredients:

Comfortis for Dogs: 5-10 lbs - Comfortis for Cats: 4.1-6 lbs (Pink Box)
Active IngredientAmount
Spinosad 140 mg
Comfortis for Dogs 10.1-20 lbs - Comfortis for Cats: 6.1-12 lbs (Orange Box)
Active IngredientAmount
Spinosad 270 mg
Comfortis for Dogs 20.1-40 lbs - Comfortis for Cats: 12.1-24 lbs (Green Box)
Active IngredientAmount
Spinosad 560 mg
Comfortis for Dogs 40.1-60 lbs (Blue Box)
Active IngredientAmount
Spinosad 810 mg
Comfortis for Dogs 60.1-120 lbs (Brown Box)
Active IngredientAmount
Spinosad 1,620 mg

What is Comfortis (spinosad)?

Comfortis is the first FDA-approved, chewable beef-flavored tablet (derived from pork protein and hydrolyzed soy) that kills fleas and prevents flea infestations on dogs and cats for a full month. Comfortis for Dogs & Cats requires a prescription from your veterinarian.

For:

Dogs & Cats (14 weeks of age or older)

Benefits:

  • Starts killing fleas within 30 minutes
  • Lasts a full month
  • Kills fleas before they can lay eggs
  • Comes in a convenient chewable, beef-flavored tablet
  • Spinosad, the active ingredient in Comfortis, is environmentally friendly

Comfortis is the #1 recommended Rx Flea-only medication for dogs and cats

How does Comfortis work?

The active ingredient in Comfortis (Spinosad) kills fleas by causing excitation of the insect's nervous system, leading to paralysis and rapid death.

Cautions:

Side effects may occur, including vomiting. If your pet is experiencing loss of appetite, lethargy, or any other difference in behavior, contact your veterinarian. The FDA has received reports of adverse reactions in dogs receiving the drug Comfortis (spinosad) concurrently with high, extra-label doses of ivermectin. Dogs receiving extra-label doses of ivermectin to treat non-responsive demodectic mange and other conditions have developed signs of ivermectin toxicity. Ivermectin is an ingredient found in heartworm preventatives such as Heartgard Plus, Heartgard, Iverhart Plus and Ivomec. In cats, the most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin. For complete safety information, see product label.

Brand Name:

Comfortis (Elanco)

Generic Name:

Spinosad

What is the most important information I should know about Comfortis?

Comfortis is a prescription medication FDA approved for use in dogs and puppies and cats and kittens 14 weeks of age or older to kill fleas and prevent flea infestations for one month. Comfortis is available in a Pink box for dogs 5 to 10 lbs and cats 4.1-6 lbs (140 mg), Orange box for dogs 10.1 to 20 lbs and cats 6.1-12 lbs (270 mg), Green box for dogs 20.1 to 40 lbs and cats 12.1-24 (560 mg), Blue box for dogs 40.1 to 60 lbs (810 mg), and Brown box for dogs 60.1 to 120 lbs (1620 mg). Please note: Cats over 24 lbs should be administered the appropriate combination of tablets.

What should I discuss with my veterinarian before giving Comfortis to my pet?

Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog or cat has a history of seizures (epilepsy).

How should Comfortis be given?

Give Comfortis chewable tablets with food. Give Comfortis chewable tablets once a month. Comfortis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose the pet with another full dose. Store Comfortis at room temperature (68-77 F)

Comfortis is an easy-to-give oral treatment that doesn't make a mess

What are the potential side effects of Comfortis?

Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Comfortis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, incoordination, weight loss, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions.Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.

What happens if I miss giving a dose of Comfortis?

Give the missed dose as soon as you remember and resume a monthly dosing schedule.

What happens if I overdose my pet on Comfortis?

Contact your veterinarian immediately.

What should I avoid while giving Comfortis?

Your pet may maintain normal activities and interactions while being given Comfortis. The safe use of Comfortis in breeding, pregnant, or lactating cats and dogs has not been evaluated.

What other drugs will affect Comfortis?

Talk to your veterinarian before giving any prescription or over the counter medications.

Comfortis is trusted by vets and has been prescribed over 90 million times

Comfortis Directions:

  • Comfortis is a prescription medication used in dogs and cats to kill fleas and prevent flea infestations for 1 month.
  • Comfortis chewable tablets are beef flavored.
  • Comfortis can be given to dogs at least 14 weeks of age, weighing at least 5 lbs, and cats 14 weeks of age, weighing at least 4 lbs.
Tip:

If vomiting occurs within 1 hour of administration, redose the pet with another tablet.

Comfortis Dosage for Dogs:

Dogs/Puppies (14 weeks of age or older):
Weight Dosage
5-10 lbs (Pink Box) Give one 140 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
10.1-20 lbs (Orange Box) Give one 270 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
20.1-40 lbs (Green Box) Give one 560 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
40.1-60 lbs (Blue Box)Give one 810 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
60.1-120 lbs (Brown Box)Give one 1620 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
Over 120 lbs Give the appropriate combination of tablets

Comfortis Dosage for Cats:

Cats/Kittens (14 weeks of age or older):
Weight Dosage
4.1-6 lbs (Pink Box) Give one 140 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
6.1-12 lbs (Orange Box) Give one 270 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
12.1-24 lbs (Green Box) Give one 560 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
Over 24 lbs Give the appropriate combination of tablets
Comfortis Dosage for Horses:
Horses
Do not use!
Storage:

Store Comfortis at room temperature (68°-77° F).

Comfortis Ingredients:

Comfortis for Dogs: 5-10 lbs - Comfortis for Cats: 4.1-6 lbs (Pink Box)
Active IngredientAmount
Spinosad 140 mg
Comfortis for Dogs 10.1-20 lbs - Comfortis for Cats: 6.1-12 lbs (Orange Box)
Active IngredientAmount
Spinosad 270 mg
Comfortis for Dogs 20.1-40 lbs - Comfortis for Cats: 12.1-24 lbs (Green Box)
Active IngredientAmount
Spinosad 560 mg
Comfortis for Dogs 40.1-60 lbs (Blue Box)
Active IngredientAmount
Spinosad 810 mg
Comfortis for Dogs 60.1-120 lbs (Brown Box)
Active IngredientAmount
Spinosad 1,620 mg