SelaSpot (selamectin) Topical for Dogs

What is SelaSpot (selamectin) Topical for Dogs?

SelaSpot™ (selamectin) for Adult Dogs is a convenient, once-monthly topical prescription treatment designed to safeguard dogs against a broad spectrum of internal and external parasites. Once applied, the solution is absorbed into the bloodstream and hair follicles to provide a full month of protection that remains effective even after bathing or swimming. It is specifically indicated to prevent heartworm disease, kill adult fleas and prevent flea eggs from hatching, and treat and control ear mites, sarcoptic mange, and American dog tick infestations.

Suitable for:

• Dogs (Adult, weighing 5+ lbs)

Benefits:

• As a macrocyclic lactone, it paralyzes and kills parasites by increasing cell membrane permeability to chloride ions.
• This topical solution containing active selamectin is safe for all breeds, including ivermectin-sensitive Collies and breeding adults.
• It prevents heartworm disease, controls the American dog tick, and treats both ear mites.
• Effectively treats and controls sarcoptic mange, protecting adult dogs from these highly contagious mites found in social settings.
• A single monthly application is quick-drying and remains fully effective even if the dog is bathed two hours later.

How does SelaSpot (selamectin) Topical for Dogs work?

In adult dogs, SelaSpot™ (selamectin) binds to glutamate-gated chloride channels in the nerve and muscle cells of parasites, inducing a constant influx of chloride ions. This ion flow causes hyperpolarization of the parasite's nervous system, resulting in rapid flaccid paralysis and death. Once applied, the medication is absorbed systemically and stored in the sebaceous glands, providing a reservoir of protection that is safe for dogs because mammals lack these specific invertebrate nerve channels.

Caution:

Before administering SelaSpot, it is essential to have dogs tested for existing heartworm infections, as the medication is not effective against adult D. immitis or for the total clearance of circulating microfilariae. At the veterinarian's discretion, infected dogs should be treated to remove adult heartworms prior to starting a preventative regimen. While hypersensitivity reactions have not been observed in heartworm-positive dogs at three times the recommended dose, safety at higher levels has not been tested. For human safety, avoid contact with skin and eyes during application, washing hands immediately with soap and water if contact occurs. Finally, because the solution is flammable, ensure it is kept away from heat, sparks, open flames, or other sources of ignition.

How should I store this product?

Keep the individual applicators in their original protective blister packaging until you are ready to use them. This protects the medication from light and moisture, which can cause the formula to break down. Store the product at or below 25˚C (77˚F).

What is the most important information I should know about SelaSpot?

SelaSpot (selamectin) Topical Parasiticide is available as a colorless to yellow, ready to use solution in single dose tubes for topical (dermal) treatment of dogs six weeks of age and older and cats eight weeks of age and older. The content of each tube is formulated to provide a minimum of 2.7 mg/lb (6 mg/kg) of body weight of selamectin. SelaSpot™ (selamectin) is a prescription-only medication that provides a full month of 'all-in-one' protection against both internal and external parasites.

What should I discuss with my veterinarian before giving SelaSpot to my pet?

Prior to treatment, your dog must be tested for existing heartworms so that any adult infections can be medically cleared by your veterinarian before starting a preventative regimen. An accurate weight check is also necessary to ensure the dosage is correct and to confirm that your dog is healthy enough for the medication. For owners of herding breeds like Collies or Australian Shepherds, it is important to discuss potential sensitivities to the active ingredient, selamectin. Finally, disclose your dog's full medical history, including any history of seizures or skin allergies, to ensure the product is the safest option for their specific needs.

How should SelaSpot be given/administered?

To apply SelaSpot, start by firmly pressing the cap down until you hear a click, which confirms the seal has been punctured, then remove the cap to verify the tip is open. Part the hair at the base of the neck until the skin is visible and squeeze the tube three or four times to dispense the entire contents in a single spot. While keeping the tube squeezed, drag it away from the liquid and lift to ensure it is completely empty. Do not massage the solution into the skin or apply it if the haircoat is wet or the skin is broken.

What are the potential side effects of SelaSpot?

Appearing in fewer than 0.5% of treated dogs; side effects included gastrointestinal issues like vomiting or diarrhea, as well as lethargy, salivation, rapid breathing, and muscle tremors. Since the product's release, additional reports have noted instances of itching, hives, and redness, along with rare cases of incoordination, fever, or seizures in dogs. While extremely rare reports of death have occurred, the vast majority of pets tolerate the treatment without significant complications.

What happens if I miss giving a dose of SelaSpot?

If you miss a dose of SelaSpot™ (selamectin), apply the missed dose as soon as you remember. Do not wait for the next scheduled date or 'double up' on doses to make up for the lapse.

What happens if I overdose my pet on SelaSpot?

If you have administered significantly more than prescribed call your veterinarian or a pet poison control center for guidance.

What special precautions are there?

If a pet ingests SelaSpot™ (selamectin), usually by licking the application site while it is still wet, they will likely experience heavy drooling or temporary vomiting due to the bitter taste and alcohol base. While these localized reactions are common and typically resolve once the taste is flushed out with water or food, the medication itself is formulated to be safe for mammals and rarely causes systemic toxicity. If your pet exhibits more severe signs such as extreme lethargy, muscle tremors, or a loss of balance, you should contact your veterinarian immediately for guidance.

What should I avoid while giving SelaSpot to my pet?

When administering SelaSpot™ (selamectin), you must avoid applying the solution to a wet haircoat or to skin that is broken, irritated, or wounded. To ensure the medication is not licked off, do not apply it to areas your pet can reach, and avoid massaging or rubbing the liquid into the skin after it is dispensed. Keep children and other household pets away from the treated area until it is completely dry to prevent accidental skin contact or ingestion. For maximum effectiveness, avoid bathing your pet or allowing them to swim for at least two hours.

What other drugs will affect SelaSpot?

SelaSpot™ is a trusted treatment that works safely with most other pet medications. It’s designed to be used alongside common treatments like vaccines, antibiotics, steroids, and dewormers without any issues. For your pet’s safety, always check with your veterinarian before combining SelaSpot™ with other medications.