Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5%
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What is Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5%?
Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5% is a non-steroidal anti-inflammatory drug (NSAID) used to treat inflammation and pain in the eyes. Though FDA-approved for humans, veterinarians may prescribe it for pets to manage conditions like post-surgical inflammation, allergic conjunctivitis, keratisis, and anterior uveitis. Ketorolac requires a prescription from your veterinarian. Solution is sold as either a 5 mL or 10 mL bottle.
Benefits:
- Begins relieving eye pain and inflammation within 1-2 hours of application.
- NSAID formula helps relieve redness, swelling, and discomfort in the eyes.
- Supports healing by minimizing ocular inflammation without the use of steroids.
- Easy to administer drops with vet-directed dosing for safe, effective use.
- Approved for extra label veterinary use in cats, dogs, and horses.
How does Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5% work?
Ketorolac Tromethamine blocks enzymes responsible for producing inflammatory compounds, helping to ease symptoms like swelling, itching, and discomfort following surgery or allergic reactions. Relief typically begins within one to two hours after application.
Caution:
Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5% should only be used under the direction of a licensed veterinarian. Do not use in animals allergic to ketorolac, aspirin, or other NSAIDs. Use with caution in pets that are pregnant, nursing, have asthma, dry eye syndrome, corneal ulcers, or bleeding disorders. Avoid touching the dropper tip to the eye or any surface to prevent contamination. Discontinue use and contact your veterinarian immediately if you notice facial swelling, difficulty breathing, skin rash, bleeding in the eye, or sensitivity to light. Do not use if the solution becomes cloudy or changes color.
How should I store this product?
Store product upright in original container with cap tightly closed. Store at controlled room temperature of 68 - 77ºF (20 - 25ºC) to maintain product integrity. Keep out of reach of children and pets.
What is the most important information I should know about Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5%?
Do not use Ketorolac Ophthalmic Solution if your pet has a corneal ulcer or bleeding disorder, or is allergic to NSAIDs such as aspirin. Stop treatment and contact your veterinarian immediately if you notice eye bleeding, severe irritation, or signs of an allergic reaction such as facial swelling or difficulty breathing.
What should I discuss with my veterinarian before giving Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5% to my pet?
Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking. Tell your veterinarian if your pet is allergic to any medications, especially NSAIDs. Inform them if your pet has asthma, dry eye syndrome, corneal ulcers, bleeding disorders, or any other eye conditions. Notify your veterinarian if your pet is pregnant, nursing, or if you plan to breed your pet.
How should Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5% be given/administered?
Administer Ketorolac Ophthalmic Solution as liquid drops directly into the eye. Wash your hands first and avoid touching the dropper tip to any surface, including the eye, to prevent contamination. If using other eye medications, wait at least 5 minutes between applications. Wipe away excess medication with a clean cloth. Do not use if the solution is cloudy or discolored. This medication usually takes effect within 1-2 hours.
What are the potential side effects of Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5%?
If any of the following serious side effects occur, stop giving Ketorolac Ophthalmic Solution and seek emergency veterinary care: allergic reaction (skin rash or hives, difficulty breathing, swelling of the face, lips, tongue, or throat), bleeding in the eye, or sensitivity to bright light.Call your veterinarian immediately if your pet develops new or worsening symptoms such as eye pain or irritation, persistent redness or discharge, infection, or delayed healing (especially after eye surgery).Less serious side effects may include temporary stinging or burning when drops are applied, or mild eye redness. Talk to your veterinarian about any reaction that seems unusual or bothersome.
What happens if I miss giving a dose of Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5%?
If you miss a dose, give it as soon as you remember. If it is close to the next scheduled dose, skip the missed dose and resume the regular schedule. Never give two doses at once or extra doses. Contact your veterinarian for guidance, especially if multiple doses are missed or your pet’s eye condition worsens.
What happens if I overdose my pet on Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5%?
When used as an eye medication overdoses are not likely, but side effects or toxic effects could occur if your animal eats the medication. If this happens contact your veterinarian or an animal poison control center for further advice. Animal poison control centers that are open 24 hours a day include ASPCA Animal Poison Control Center (888-426-4435) and Pet Poison HELPLINE (855764-7661); a consultation fee may be charged for these services.
What special precautions are there?
Use with caution in pets with bleeding disorders or delayed healing, as this medication may increase bleeding time and slow corneal healing. Monitor for signs of eye irritation or keratitis. Has not been tested in pregnant or lactating pets — use only if prescribed by your veterinarian. Use of this drug may not be allowed in certain animal competitions. Check rules and regulations before entering your animal in a competition while this medication is being administered.
What should I avoid while giving Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5% to my pet?
Avoid touching the dropper tip to the eye or any surface to prevent contamination. Do not use the medication if the solution appears cloudy, discolored, or contains particles. Never share this medication with other pets, and avoid extending treatment beyond your veterinarian’s instructions. Store the bottle properly and keep it out of reach of children and other animals.
What other drugs will affect Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5%?
Ketorolac Tromethamine eye drops may interact with other NSAIDs (aspirin, ibuprofen, or carprofen), anticoagulants (warfarin), and antiplatelet drugs (clopidogrel), increasing the risk of bleeding. Use caution if your pet is on blood thinners or has clotting disorders, since ketorolac can affect platelet function. Combining with corticosteroids (prednisone, dexamethasone) can also raise the risk of corneal issues, ulcers, and delayed healing. Do not give any other prescription or over-the-counter medications, including eye drops, supplements, or herbal products, without first consulting your veterinarian.
Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5% Directions:
- Administer this drug to your animal’s eye in the exact amount that your veterinarian has prescribed.
- Wash your hands before administering this medication.
- Do not touch the dropper tip or allow it to touch your animal’s eye or any other surface to prevent contamination.
- If any residue is left on your animal’s face after giving the eye drops, gently wipe it off with a damp cloth or tissue.
- If you are administering more than one eye medication to your animal, wait 5 minutes between each medication before giving the next one.
- Use eye drops before eye ointments to allow the drops to absorb into the eye.
- If you are using this medication as an eye solution for your horse, your veterinarian may have implanted a special eye catheter (subpalpebral lavage or SPL catheter). Use this catheter exactly as your veterinarian has prescribed and only use air to flush the medications to the eye after injecting into the catheter.
- If you are having difficulty applying the medication or your animal does not accept the treatment, contact your veterinarian or pharmacist for tips to help with administration and reducing the stress of medication time.
Warm the eye drop bottle in your hands for a minute, then wrap your pet in a soft towel “burrito” for a stress-free and cozy application.
Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5% Dosage:
| Condition | Dosage |
|---|---|
| Active uveitis or Conjunctivitis | Administer 2 to 3 times daily |
| Chronic uveitis | Administer 1 to 2 times daily |
| Pre and Post Surgery | Administer 2 to 3 times daily over 2 days BEFORE surgery; may be continued for several days after surgery |
| Dosage varies based on the condition being treated, your pet’s response to therapy, age, weight, and any potential adverse effects. Administer only as prescribed by your veterinarian. |
|---|
| Condition | Dosage |
|---|---|
| Active uveitis or Conjunctivitis | Administer 2 to 3 times daily |
| Chronic uveitis | Administer 1 to 2 times daily |
| Pre and Post Surgery | Administer 2 to 3 times daily over 2 days BEFORE surgery; may be continued for several days after surgery |
| Dosage varies based on the condition being treated, your pet’s response to therapy, age, weight, and any potential adverse effects. Administer only as prescribed by your veterinarian. |
|---|
| Condition | Dosage |
|---|---|
| All conditions | Dosage varies based on the condition being treated, your pet’s response to therapy, age, weight, and any potential adverse effects. Administer only as prescribed by your veterinarian. |
Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5% Ingredients:
| Active Ingredient | Amount (per 1 mL) |
|---|---|
| KETOROLAC TROMETHAMINE | 5 mg |
| Sodium Chloride, Edetate Disodium, Octoxynol-40, Hydrochloric Acid, Water, Benzalkonium Chloride, Sodium Hydroxide. |
|---|












