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Simparica

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Starts $54.44 $37.06 
Ships in one business day or less

Step 1. Select Pet's Weight:

Dog

Step 2. Select a Supply:

3 pack
$54.44
$46.33
$37.06
Price w/coupon SAVE20
6 pack
$108.08
$91.98
$73.58
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12 pack
$208.33
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$141.84
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Save $6 over 3 pk
Starts $54.44 $37.06 
Ships in one business day or less

Step 1. Select Pet's Weight:

Dog

Step 2. Select a Supply:

3 pack
$54.44
$46.33
$37.06
Price w/coupon SAVE20
6 pack
$108.08
$91.98
$73.58
Price w/coupon SAVE20
Free Shipping
12 pack
$208.33
$177.30
$141.84
Price w/coupon SAVE20
Free Shipping
Save $6 over 3 pk

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Product Info

What is Simparica?

Simparica is a fast-acting oral flea and tick preventative that begins killing fleas and ticks within hours of administration and remains effective for one month to prevent re-infestations. It is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Amblyomma americanum (Lone Star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (deer tick/black-legged tick), and Rhipicephalus sanguineus (brown dog tick)]. Simparica begins to kill adult fleas within 3 hours and ticks within 8 hours of administration. Treatment with Simparica may begin at any time of the year and is safe to use year-round without interruption. Simparica is given monthly and requires a prescription from your veterinarian.

For:

Dogs (6+ months of age, weighing 2.8+ lbs)

Benefits:

  • Each tablet provides a full month of protection against fleas and ticks
  • Tasty, liver-flavored chewable tablet is easy to administer
  • Chewable tablets can be given directly to your dog or broken up and mixed with food
  • Available in six weight categories: 2.8-5.5 lbs, 5.6-11 lbs, 11.1-22.0 lbs, 22.1-40 lbs, 44.1-88.0 lbs and 88.1-132 lbs

How does Simparica work?

Simparica contains the active ingredient sarolaner, which inhibits the function of the neurotransmitter gamma aminobutyric acid (GABA) receptor and glutamate receptor, and works at the neuromuscular junction in insects. This results in uncontrolled neuromuscular activity leading to death in insects or acarines. Simparica is administered once a month directly by mouth or can be crumbled and mixed with food. To minimize the likelihood of flea re-infestation, it is important to treat all dogs and cats within a household with an approved flea control product.

Cautions:

Not for use in humans. Keep this and all drugs out of reach of children and pets. For use in dogs only. Do not use Simparica in cats. Simparica should not be used in dogs less than 6 months of age weighing less than 2.8 lbs. The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs.

Brand Name

Simparica (Zoetis)

Generic Name

Sarolaner (sar-oh-lan-ur)

What is the most important thing I should know about Simparica?

Simparica is used for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Amblyomma americanum (Lone Star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (deer tick/black-legged tick), and Rhipicephalus sanguineus (brown dog tick)] in dogs over 6 months of age weighing 2.8 lbs and over. Simparica is available as a liver-flavored, chewable tablet. Simparica requires a prescription from your veterinarian.

What should I discuss with my veterinarian before giving Simparica to my pet?

Tell your veterinarian if your pet is breeding, pregnant, or lactating.

How Simparica should be given?

Simparica should be administered orally, once every month, at the minimum dosage of 0.91 mg/lb (2 mg/kg) sarolaner. Dogs weighing 2.8 to 5.5 lbs should be given one 5 mg Simparica chewable tablet monthly. Dogs weighing 5.6 to 11.0 lbs should be given one 10 mg Simparica chewable tablet monthly. Dogs weighing 11.1 to 22.0 lbs should be given one 20 mg Simparica chewable tablet monthly. Dogs weighing 22.1 to 44.0 lbs should be given one 40 mg Simparica chewable tablet monthly. Dogs weighing 44.1 to 88.0 lbs should be given one 80 mg Simparica chewable tablet monthly. Dogs weighing 88.1 to 132.0 lbs should be given one 120 mg Simparica chewable tablet monthly. Dogs weighing more than 132.0 lbs should be given appropriate combination of Simparica tablets monthly. Care should be taken that your dog consumes the complete dose, and treated pets should be observed for a few minutes to ensure that part of the dose is not lost or refused.

For flea treatment and prevention: Treatment may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with Simparica can continue the entire year without interruption. To minimize the likelihood of flea re-infestation, it is important to treat all dogs and cats within a household with an approved flea control product.

For tick treatment and control: Treatment with Simparica can begin at any time of the year.

What are the potential side effects of Simparica?

The most frequently reported adverse reactions were vomiting and diarrhea. Simparica may cause abnormal neurologic signs such as tremors, decreased conscious proprioception [awareness of body position and movement], ataxia [loss of full control of bodily movements], decreased or absent menace [blinking reflex], and/or seizures.

What happens if I miss giving a dose of Simparica?

If a dose is missed, administer Simparica and resume a monthly dosing schedule.

What happens if I overdose my pet on Simparica?

Contact your veterinarian immediately.

What should I avoid while giving Simparica to my pet?

Do not use Simparica in cats. Simparica should not be used in dogs less than 6 months of age. The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs.

What other drugs will affect Simparica?

There are no known contraindications for the use of Simparica.

How to Use

Simparica Directions:

  • Administer one Simparica chewable once every month.
  • Simparica may be offered by hand or broken into pieces and fed to dogs that normally swallow treats whole.
  • Simparica chewables should be administered in a manner that encourages your dog to chew, rather than to swallow without chewing. Care should be taken to be sure that your dog consumes the complete dose.
  • Observe your dog for a few minutes after administration to ensure that no part of the dose is lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.
Tip:

Always make sure ample water is available for your dog.

Simparica Dosage for Dogs:

Dogs/Puppies: (6+ months of age, weighing 2.8+ lbs)
WeightDosage
2.8-5.5 lbs One 5 mg chewable tablet monthly
5.6-11.0 lbsOne 10 mg chewable tablet monthly
11.1-22.0 lbsOne 20 mg chewable tablet monthly
22.1-44.0 lbsOne 40 mg chewable tablet monthly
44.1-88.0 lbs One 80 mg chewable tablet monthly
88.1-132.0 lbsOne 120 mg chewable tablet monthly
Over 132.1 lbsAdminister the appropriate combination of Simparica chewable tablets monthly
Simparica Dosage for Cats:
Cats
Do not use!
Simparica Dosage for Horses:
Horses
Do not use!
Storage:

Store at or below 86F (30C) with excursions permitted up to 104F (40C).

Ingredients

Simparica Ingredients:

Simparica for Dogs 2.8-5.5 lbs:
Active Ingredient (per tablet)Amount
Sarolaner5 mg
Simparica for Dogs 5.6-11 lbs:
Active Ingredient (per tablet)Amount
Sarolaner10 mg
Simparica for Dogs 11.1-22.0 lbs:
Active Ingredient (per tablet)Amount
Sarolaner20 mg
Simparica for Dogs 22.1-44.0 lbs:
Active Ingredient (per tablet)Amount
Sarolaner40 mg
Simparica for Dogs 44.1-88.0 lbs:
Active Ingredient (per tablet)Amount
Sarolaner80 mg
Simparica for Dogs 88.1-132.0 lbs:
Active Ingredient (per tablet)Amount
Sarolaner120 mg
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