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Revolution Plus

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What is Revolution Plus?

Revolution Plus is a safe and effective monthly topical medication that provides 6-in-1 protection for cats. Revolution Plus kills fleas before they lay eggs, and kills ticks for a full month. In comparison to Revolution for cats, Revolution Plus kills 3 types of ticks (black-legged tick, Gulf Coast tick, and American dog tick) for a full month. It also prevents heartworm disease and treats and controls ear mites, roundworms, and hookworms. Revolution Plus is easy to apply and is a quick-drying solution for a mess-free administration. Revolution Plus requires a prescription from your veterinarian.

Suitable For:

Cats and Kittens (8 weeks of age and older, weighing at least 2.8 lbs)

Benefits:

  • Kills fleas before they lay eggs
  • Kills ticks for a full month
  • Prevents heartworm disease
  • Treats and controls ear mites, roundworms, and hookworms.
  • Safe and effective
  • Quick-drying solution
  • Once a month administration

How does Revolution Plus work?

Revolution Plus contains two active ingredients, selamectin and sarolaner, which absorbs into the skin and enter the bloodstream. Combined, these ingredients start killing fleas within 6 hours of administration, begin to kill ticks within 24 hours of administration, prevent the development of heartworm, and eliminate and control ear mites and other worms.

Cautions:

IMPORTANT SAFETY INFORMATION:   The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats.  Reported side effects in clinical trials included lethargy and anorexia.  Use with caution in cats with a history of neurologic disorders.  Revolution Plus contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions, such as tremors, ataxia, and seizures in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes.

Brand Name:

Revolution Plus

Generic Name:

Selamectin, sarolaner

What is the most important thing I should know about Revolution Plus?

Revolution Plus is a topical medication for cats that is applied topically once a month. Revolution Plus provides 6-in-1 protection against fleas, ticks (black-legged tick, Gulf Coast tick, and American dog tick), heartworms, ear mites, roundworms, and hookworms. In humans, Revolution Plus may be irritating to skin and eyes. Make sure to wash hands after application.

What should I discuss with my veterinarian before giving Revolution Plus to my pet?

Tell your veterinarian if your cat is pregnant, breeding, or lactating. If your cat has a history of neurologic disorders, tell your veterinarian.

How should Revolution Plus be applied to my pet?

Apply Revolution Plus exactly as directed by your veterinarian. Revolution Plus comes in single-use tubes for easy administration. Press the cap down to puncture the seal on the tube. A clicking sound will confirm the seal has been punctured. Remove the cap and make sure the tip of the tube is open. To administer, part the hair on the back of your cat at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the tube on the skin and empty the contents of the tube in one spot. Do not massage the product into the skin or apply to broken skin. Additionally, don't apply if your cat's coat is wet. Avoid contact between the product and your fingers. Wash your hands when you have finished applying Revolution Plus to your cat.

What are the potential side effects of Revolution Plus?

Reported side effects include lethargy and anorexia.

What happens if I miss giving a dose of Revolution Plus?

Give the next dose as soon as you remember and resume a normal monthly dosing schedule.

What happens if I overdose my pet on Revolution Plus?

If an overdose is suspected, contact your veterinarian immediately.

What should I avoid while giving Revolution Plus to my pet?

Avoid getting the product on your fingers. Wash your hands when finished applying the product on your cat.

What other drugs will affect Revolution Plus?

There are no known contraindications for the use of Revolution Plus.

Revolution Plus Directions:

  • Firmly press the cap down to puncture the seal on the tube. A clicking sound will confirm that the seal has been punctured.
  • Remove the cap and check to ensure the tip of the tube is open.
  • Part the hair on the back of your cat at the base of the neck in front of the shoulder blades until the skin is visible.
  • Place the tip of the tube on the skin and empty the entire contents of the tube in one spot.
  • Check to make sure the tube is empty
  • Cats over 22 lbs should be treated with the appropriate combination of tubes.
Tip:

Don't massage the topical into the skin. Don't apply to broken skin, and don't apply if the coat is wet

Revolution Plus Dosage:

Revolution Plus Dosage for Cats
Weight Dosage
2.8-5.5 lbs Apply contents of one 0.25 ml tube once a month (Gold).
5.6-11 lbs Apply contents of one 0.5 ml tube once a month (Orange).
11.1-22 lbs Apply contents of one 1 ml tube once a month (Green).
Revolution Plus Dosage for Dogs
Dogs
Do not use!
Revolution Plus Dosage for Horses
Horses
Do not use!

Storage:

Store at or below room temperature. Keep out of the reach of children and pets.

Revolution Plus Ingredients:

Revolution Plus for Cats 2.8-5.5 lbs
Active Ingredients (per tube) Amount
Selamectin 15 mg
Sarolaner 2.5 mg
Revolution Plus for Cats 5.6-11 lbs
Active Ingredients (per tube) Amount
Selamectin 30 mg
Sarolaner 5 mg
Revolution Plus for Cats 11.1-22 lbs
Active Ingredients (per tube) Amount
Selamectin 60 mg
Sarolaner 10 mg

What is Revolution Plus?

Revolution Plus is a safe and effective monthly topical medication that provides 6-in-1 protection for cats. Revolution Plus kills fleas before they lay eggs, and kills ticks for a full month. In comparison to Revolution for cats, Revolution Plus kills 3 types of ticks (black-legged tick, Gulf Coast tick, and American dog tick) for a full month. It also prevents heartworm disease and treats and controls ear mites, roundworms, and hookworms. Revolution Plus is easy to apply and is a quick-drying solution for a mess-free administration. Revolution Plus requires a prescription from your veterinarian.

Suitable For:

Cats and Kittens (8 weeks of age and older, weighing at least 2.8 lbs)

Benefits:

  • Kills fleas before they lay eggs
  • Kills ticks for a full month
  • Prevents heartworm disease
  • Treats and controls ear mites, roundworms, and hookworms.
  • Safe and effective
  • Quick-drying solution
  • Once a month administration

How does Revolution Plus work?

Revolution Plus contains two active ingredients, selamectin and sarolaner, which absorbs into the skin and enter the bloodstream. Combined, these ingredients start killing fleas within 6 hours of administration, begin to kill ticks within 24 hours of administration, prevent the development of heartworm, and eliminate and control ear mites and other worms.

Cautions:

IMPORTANT SAFETY INFORMATION:   The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats.  Reported side effects in clinical trials included lethargy and anorexia.  Use with caution in cats with a history of neurologic disorders.  Revolution Plus contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions, such as tremors, ataxia, and seizures in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes.

Brand Name:

Revolution Plus

Generic Name:

Selamectin, sarolaner

What is the most important thing I should know about Revolution Plus?

Revolution Plus is a topical medication for cats that is applied topically once a month. Revolution Plus provides 6-in-1 protection against fleas, ticks (black-legged tick, Gulf Coast tick, and American dog tick), heartworms, ear mites, roundworms, and hookworms. In humans, Revolution Plus may be irritating to skin and eyes. Make sure to wash hands after application.

What should I discuss with my veterinarian before giving Revolution Plus to my pet?

Tell your veterinarian if your cat is pregnant, breeding, or lactating. If your cat has a history of neurologic disorders, tell your veterinarian.

How should Revolution Plus be applied to my pet?

Apply Revolution Plus exactly as directed by your veterinarian. Revolution Plus comes in single-use tubes for easy administration. Press the cap down to puncture the seal on the tube. A clicking sound will confirm the seal has been punctured. Remove the cap and make sure the tip of the tube is open. To administer, part the hair on the back of your cat at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the tube on the skin and empty the contents of the tube in one spot. Do not massage the product into the skin or apply to broken skin. Additionally, don't apply if your cat's coat is wet. Avoid contact between the product and your fingers. Wash your hands when you have finished applying Revolution Plus to your cat.

What are the potential side effects of Revolution Plus?

Reported side effects include lethargy and anorexia.

What happens if I miss giving a dose of Revolution Plus?

Give the next dose as soon as you remember and resume a normal monthly dosing schedule.

What happens if I overdose my pet on Revolution Plus?

If an overdose is suspected, contact your veterinarian immediately.

What should I avoid while giving Revolution Plus to my pet?

Avoid getting the product on your fingers. Wash your hands when finished applying the product on your cat.

What other drugs will affect Revolution Plus?

There are no known contraindications for the use of Revolution Plus.

Revolution Plus Directions:

  • Firmly press the cap down to puncture the seal on the tube. A clicking sound will confirm that the seal has been punctured.
  • Remove the cap and check to ensure the tip of the tube is open.
  • Part the hair on the back of your cat at the base of the neck in front of the shoulder blades until the skin is visible.
  • Place the tip of the tube on the skin and empty the entire contents of the tube in one spot.
  • Check to make sure the tube is empty
  • Cats over 22 lbs should be treated with the appropriate combination of tubes.
Tip:

Don't massage the topical into the skin. Don't apply to broken skin, and don't apply if the coat is wet

Revolution Plus Dosage:

Revolution Plus Dosage for Cats
Weight Dosage
2.8-5.5 lbs Apply contents of one 0.25 ml tube once a month (Gold).
5.6-11 lbs Apply contents of one 0.5 ml tube once a month (Orange).
11.1-22 lbs Apply contents of one 1 ml tube once a month (Green).
Revolution Plus Dosage for Dogs
Dogs
Do not use!
Revolution Plus Dosage for Horses
Horses
Do not use!

Storage:

Store at or below room temperature. Keep out of the reach of children and pets.

Revolution Plus Ingredients:

Revolution Plus for Cats 2.8-5.5 lbs
Active Ingredients (per tube) Amount
Selamectin 15 mg
Sarolaner 2.5 mg
Revolution Plus for Cats 5.6-11 lbs
Active Ingredients (per tube) Amount
Selamectin 30 mg
Sarolaner 5 mg
Revolution Plus for Cats 11.1-22 lbs
Active Ingredients (per tube) Amount
Selamectin 60 mg
Sarolaner 10 mg

LEARN MORE ABOUT


Because Every Cat Needs Parasite Protection

Revolution Plus is a monthly topical solution that protects your cat against most common feline parasites: fleas, ticks, ear mites, roundworms, hookworms, and heartworms.

20 Years of Proven Protection*

Revolution Plus is the most prescribed medicine for feline parasite protection.1

Safe for cats and kittens as young as 8 weeks of age, weighing 2.8 lbs or more.

Simple-to-apply, quick-drying, small-volume, monthly topical solution.

Pest Protection for
Indoor & Outdoor Cats

Protect your cat from the most common parasites by
combining the power of selamectin and sarolaner.

  • Flea & Flea Eggs
  • Ticks
  • Ear Mites
  • Roundworms
  • Hookworms
  • Heartworm Disease
Easy Application

Revolution Plus is easy to apply and eliminates the need for multiple
treatments, simplifying your cat's parasite protection routine.

Press Cap Until
You Hear a “CLICK”


Hold tube upright and press the cap to puncture the seal. Remove cap and make sure tip is open.

Part Neck Hair &
Squeeze Tube


Part the fur at the base of your cat’s neck and touch tube tip to visible skin. Squeeze tube 3 or 4 times in one spot.

Glide Tube, Lift
and Discard


Keeping the tube squeezed, glide it along the skin and away from the liquid, then lift off. Ensure the tube is empty before throwing it out.

Which Product is Right for My Cat?

2.8 - 5.5 lbs

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5.6 - 11 lbs

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11.1 - 22 lbs

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REFERENCES
1. Vetstreet FTH Projection February 2021. Canine and Feline Flea, Tick, Heartworm Market Share. February 2021. Data on file. Zoetis Inc.
2. Revolution Plus (selamectin and sarolaner topical solution). Package insert. Zoetis Inc; 2018.
3. Zoetis Data on File, Study Report A181C-US-15-166, 2017.

*Revolution Plus is veterinarians’ #1 trusted choice in feline parasite protection, built upon the proven 20-year legacy protection of Revolution (selamectin).

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