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Comfortis

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Starts $132.18 $89.99 
Ships in one business day or less

Step 1. Select Pet's Weight:

Dog
Cat

Step 2. Select a Supply:

6 pack
$132.18
$112.49
$89.99
Price w/coupon SAVE20
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12 pack
$256.97
$218.70
$174.96
Price w/coupon SAVE20
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Save $5 over 6 pk
Starts $132.18 $89.99 
Ships in one business day or less

Step 1. Select Pet's Weight:

Dog
Cat

Step 2. Select a Supply:

6 pack
$132.18
$112.49
$89.99
Price w/coupon SAVE20
Free Shipping
12 pack
$256.97
$218.70
$174.96
Price w/coupon SAVE20
Free Shipping
Save $5 over 6 pk

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Product Info

What is Comfortis?

Comfortis is the first FDA-approved, chewable beef-flavored tablet (derived from pork protein and hydrolyzed soy) that kills fleas and prevents flea infestations on dogs and cats for a full month. Comfortis for Dogs & Cats requires a prescription from your veterinarian.

For:

Dogs & Cats (14 weeks of age or older)

Benefits:

  • Starts killing fleas within 30 minutes
  • Lasts a full month
  • Kills fleas before they can lay eggs
  • Comes in a convenient chewable, beef-flavored tablet
  • Spinosad, the active ingredient in Comfortis, is environmentally friendly

How does Comfortis work?

The active ingredient in Comfortis (Spinosad) kills fleas by causing excitation of the insect's nervous system, leading to paralysis and rapid death.

Cautions:

Side effects may occur, including vomiting. If your pet is experiencing loss of appetite, lethargy, or any other difference in behavior, contact your veterinarian. The FDA has received reports of adverse reactions in dogs receiving the drug Comfortis (spinosad) concurrently with high, extra-label doses of ivermectin. Dogs receiving extra-label doses of ivermectin to treat non-responsive demodectic mange and other conditions have developed signs of ivermectin toxicity. Ivermectin is an ingredient found in heartworm preventatives such as Heartgard Plus, Heartgard, Iverhart Plus and Ivomec. In cats, the most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin.

Brand Name:

Comfortis (Elanco)

Generic Name:

Spinosad

What is the most important information I should know about Comfortis?

Comfortis is a prescription medication FDA approved for use in dogs and puppies and cats and kittens 14 weeks of age or older to kill fleas and prevent flea infestations for one month. Comfortis is available in a Pink box for dogs 5 to 10 lbs and cats 4-6 lbs (140 mg), Orange box for dogs 10.1 to 20 lbs and cats 6.1-12 lbs (270 mg), Green box for dogs 20.1 to 40 lbs and cats 12.1-24 (560 mg), Blue box for dogs 40.1 to 60 lbs (810 mg), and Brown box for dogs 60.1 to 120 lbs (1620 mg). Please note: Cats over 24 lbs should be administered the appropriate combination of tablets.

What should I discuss with my veterinarian before giving Comfortis to my pet?

Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog or cat has a history of seizures (epilepsy).

How should Comfortis be given?

Give Comfortis chewable tablets with food. Give Comfortis chewable tablets once a month. Comfortis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose the pet with another full dose. Store Comfortis at room temperature (68-77 F)

What are the potential side effects of Comfortis?

Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Comfortis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.

What happens if I miss giving a dose of Comfortis?

Give the missed dose as soon as you remember and resume a monthly dosing schedule.

What happens if I overdose my pet on Comfortis?

Contact your veterinarian immediately.

What should I avoid while giving Comfortis?

Your pet may maintain normal activities and interactions while being given Comfortis. The safe use of Comfortis in breeding, pregnant, or lactating cats and dogs has not been evaluated.

What other drugs will affect Comfortis?

Talk to your veterinarian before giving any prescription or over the counter medications.

How to Use

Comfortis Directions:

  • Comfortis is a prescription medication used in dogs and cats to kill fleas and prevent flea infestations for 1 month.
  • Comfortis chewable tablets are beef flavored.
  • Comfortis can be given to dogs at least 14 weeks of age, weighing at least 5 lbs, and cats 14 weeks of age, weighing at least 4 lbs.
Tip:

If vomiting occurs within 1 hour of administration, redose the pet with another tablet.

Comfortis Dosage for Dogs:

Dogs/Puppies (14 weeks of age or older):
Weight Dosage
5-10 lbs (Pink Box) Give one 140 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
10.1-20 lbs (Orange Box) Give one 270 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
20.1-40 lbs (Green Box) Give one 560 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
40.1-60 lbs (Blue Box)Give one 810 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
60.1-120 lbs (Brown Box)Give one 1620 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
Over 120 lbs Give the appropriate combination of tablets

Comfortis Dosage for Cats:

Cats/Kittens (14 weeks of age or older):
Weight Dosage
4-6 lbs (Pink Box) Give one 140 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
6.1-12 lbs (Orange Box) Give one 270 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
12.1-24* lbs (Green Box) Give one 560 mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications
Comfortis Dosage for Horses:
Horses
Do not use!
Storage:

Store Comfortis at room temperature (68-77 F).

Ingredients

Comfortis Ingredients:

Comfortis for Dogs: 5-10 lbs - Comfortis for Cats: 4-6 lbs (Pink Box)
Active IngredientAmount
Spinosad 140 mg
Comfortis for Dogs 10.1-20 lbs - Comfortis for Cats: 6.1-12 lbs (Orange Box)
Active IngredientAmount
Spinosad 270 mg
Comfortis for Dogs 20.1-40 lbs - Comfortis for Cats: 12.1-24 lbs (Green Box)
Active IngredientAmount
Spinosad 560 mg
Comfortis for Dogs 40.1-60 lbs (Blue Box)
Active IngredientAmount
Spinosad 810 mg
Comfortis for Dogs 60.1-120 lbs (Brown Box)
Active IngredientAmount
Spinosad 1,620 mg
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