What is Amitriptyline?
Amitriptyline is a tricyclic antidepressant. It's used to treat certain behavioral problems, such as separation anxiety, fear of noises, and anxiety in dogs. For cats it is used to treat urinating out of the litter box, spraying, and anxiety. Amitriptyline requires a prescription from your veterinarian.
Note: Amitriptyline Compounded is also available.
Cats and Dogs
- Treats behavioral issues in dogs, such as separation anxiety
- Remedies feline behavioral problems, like urinating outside the litter box
- Reduces the frequency of vet visits
How does Amitriptyline work?
Amitriptyline affects chemicals in the brain that become unbalanced, leading to behavioral problems in your pet.
Side effects of Amitriptyline may include drowsiness, dizziness, loss of appetite, and urinary retention, and this product may interact with other products your pet is taking.
What should I discuss with my veterinarian before giving Amitriptyline to my pet?
Do not give this medication if your pet has taken or used a monoamine oxidase inhibitor (MAOI) such as selegiline, Mitaban Dip or Preventic Collar within the last 14 days. Tell your veterinarian if your pet has liver or kidney disease; asthma; thyroid disease; diabetes; stomach or intestinal problems; high blood pressure or heart disease; difficulty urinating, or glaucoma. Tell your veterinarian if the pet is pregnant or lactating.
What is the most important information I should know about Amitriptyline?
Amitriptyline is a prescription medication not FDA approved for veterinary use; however, it is a commonly accepted practice for veterinarians to use this medication in dogs and cats. Amitriptyline is available as 10mg, 25mg, 50mg and 75mg tablets. The usual initial dose for dogs is 0.5-2mg per pound every 8-12 hours. The usual dose in cats is 5-10mg per cat once a day, at night. This medication may not help symptoms right away. It may take a number of days before symptoms begin to lessen. Contact your veterinarian if symptoms get worse or if new symptoms develop while the pet is on this medication. Amitriptyline may cause drowsiness or dizziness.
How should Amitriptyline be given?
Give this medication exactly as directed by your veterinarian. Allow pet to drink plenty of water. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Do not stop giving Amitriptyline suddenly. This could cause symptoms such as nausea, headache and malaise. Store Amitriptyline at room temperature away from moisture and heat. Keep this medication away from children and pets.
What happens if I miss giving a dose of Amitriptyline?
Give the missed dose as soon as you remember. However, if is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.
What should I avoid while giving Amitriptyline to my pet?
Amitriptyline may cause dizziness or drowsiness.
What are the possible side effects of Amitriptyline?
If any of the following serious side effects occur, stop giving Amitriptyline and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face, or hives); seizures; a fast or irregular heartbeat; high blood pressure; difficulty urinating; panting, muscle stiffness or severe muscle weakness. Other less serious side effects may occur. Continue giving Amitriptyline and talk to your veterinarian if your pet has drowsiness or dizziness; dry mouth and eyes; constipation; panting; mild agitation, weakness or headache; nausea or loss of weight or appetite. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.
What other drugs will affect Amitriptyline?
Do not give this medication if your pet has taken or used a monoamine oxidase inhibitor (MAOI) such as selegiline, Mitaban Dip or Preventic Collar within the last 14 days. Amitriptyline may increase the effects of other drugs that may cause drowsiness, including other antidepressants, antihistamines, sedatives, pain relievers, anxiety medications, and muscle relaxants. Drugs other than those listed may also interact with Amitriptyline. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines including herbal products.
- Amitriptyline is a tricyclic antidepressant available by prescription for use in dogs to treat certain behavioral problems such as separation anxiety, fear of noises, and anxiety.
- Amitriptyline is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to prescribe this medication for dogs and cats.
- Amitriptyline is used in cats to treat urinating out of the litter box, spraying, and anxiety.
- Do not give this medication if your pet is or has been using an MAOi (monoamine oxidase inhibitor) such as Selegiline, Anipryl, Mitaban Dip, or Preventic Collar within the last 14 days.
It may take a number of days before symptoms begin to lessen. Allow pet to drink plenty of water. Do not stop giving Amitriptyline suddenly.
The usual initial dose is 0.5-2 mg per pound of pet's body weight every 8-12 hours
The usual dose is 5-10 mg once a day, at night
Store Amitriptyline at room temperature away from moisture and heat.
Amitriptyline HCl is rated
Rated 1 out of
Something is VERY wrong with these pills
So I have been using 1800petmeds for the last several years. My cat has behavioral problems and is prescribed Amitriptyline. Last year I received my usual prescription but when I opened the bottle I noticed that the pills were half the size (10mg) that they use to be. I looked at the label and it stated that they were 10mg tablets manufactured by Sandoz. I wasn't that worried since I do know that pills can come in various sizes depending on how much inert ingredients are put in the tablet. After two weeks of administering the tablet to my cat I noticed a dramatic change in her behavior. She started becoming more anti social, aggressive and pulling out large clumps of hair from her stomach, which was her behavior prior to being treated with Amitriptyline. I looked at the bottle again and peeled the label off showing another label underneath. It also said 10mg tablet however the maker was Intas Pharmaceuticals in India. Having absolutely no doubt that the pills were 5mg instead of 10mg I ended up administering two pills and noticed that my cat returned to her calm behavior. I ordered some more hoping that the prescription would be correct and the manufacturer would be Sandoz. Unfortunately it was what I received before. I have since gone to another petRX company and just received a new bottle with pills the same size of the original 10 mg with the manufacturer being Sandoz. I still have the medication manufactured by Intas Pharmaceuticals and I'm trying to find out where I can take it to have it tested for its potency and will call my Vet for advice. Also before anyone freaks out about doubling the medication I called my Vet and told her what was occurring and that I believe the dosage is incorrect. Based on my cats size (very large) the only adverse effect would be making her sleepy. Since my cat did not become drowsy after giving her two pills and she was no longer pulling her fur out in clumps I believe this confirms that the dosage of the pill was 5mg instead of 10mg as the label said. Since purchasing from another company the pill size appears correct and her behavior has stabilized.
Date published: 2017-03-08
Rated 5 out of
My Zoe does great on Amitriptyline!
My dog, Zoe has been on this medication for a few years. I always purchase from PetMeds. The service, quality, pricing and shipping is flawless.
Date published: 2017-01-19
Rated 5 out of
My vet prescribed amitriptylene for my kitty who has psychogenic alopoecia and it calmed her. Most important, her hair grew back. As soon as the prescription was completed, my kitty started chewing her hair out again. I called the Vet, the won't renew the prescription until I bring the cat back and undergo a barrage of tests which, amounts to a $400 vet visit. I'm a senior on Medicare. I can't afford that. I was hoping to purchase the product directly from you but, found that I could not do so. Amitriptylene works and I'm glad for the other reviewers who have experienced betterment in their animals.
Date published: 2016-12-10
Rated 5 out of
This predict has helped Shans a great deal. She is going to be twelve this year and really never be cured. It's no fun for her. But the product helps
Date published: 2015-08-09
Rated 5 out of
Love this product
My dog was eating his backside. He has drawn blood it was so bad. The first 2 days using the medicine, I also had him wear a cone. His sores cleared up and he is good.
Date published: 2015-05-04
Rated 5 out of
Works wonders for our dogs.
Our girls used to get into fights and become aggressive towards each other. With the Amitriptyline they are calmer and for over a year we have had no fights. We have two Old English Sheepdogs and when they get into it, it is not pretty. Glad we were able to find something to help with them getting along all the time.
Date published: 2014-09-30
Rated 3 out of
Hasn't worked for us yet
I had such high hopes for this medication, but after 4 weeks on it (10 mg a day) my 5-year old neutered male Sammie is still spraying and going outside the box. We got him as a rescue about 2 months ago and he started spraying a few days after coming here. Had been told the reason he'd been given up was for spraying but the rescue place said they'd never seen him spray so I thought I'd take a chance on him. We have another cat (they get along OK but do have the ocassional altercation) and a dog who ignores him. Sammie was found to have some crystals in his urine, so he's been on Prescription Diet c/d. Was tested last week and still has a few crystals; was put on an antibiotic because they found a few red & white blood cells in his urine, too. The antibiotic gave him diarrhea, but thank goodness he at least does #2 in the litter boxes. The vet says she wants to clear up his urine before trying another medication, which I guess I can understand, but cleaning up after him every day is no fun. I can easily see why spraying is the #1 reason for turning in a beloved kitty cat, but I haven't given up on this guy yet. The vet suggested I get a leash and harness for him and get him outside, as that might help. I'll try anything at this point. There's also a new Prescription Diet food for "urinary stress" which I'll try. One of the vet techs says it helped her mother's spraying cat enormously.
Date published: 2014-07-26
Rated 4 out of
kitty uses litter box again
Honeycat was semi-feral when I adopted her, and she's always been nervous. I've had her 10 months and suddenly she started going outside the litter box. I suspected it was her nerves, and a urinary test cleared her of medical issues, so the vet prescribed amitriptyline to settle her down and make her feel more secure so she doesn't need to "mark" territory. The one drawback is that it's hard to get her to take the pills, especially half-pills, because they are so bitter.
Date published: 2014-02-17