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Advantage Multi

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Starts $116.24 $82.44 
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info

What is Advantage Multi?

Advantage Multi is an effective, convenient monthly topical solution for dogs and cats. It offers broad spectrum parasite protection in one easy application.

Advantage Multi for Dogs offers heartworm disease prevention that forgives if you forget. We all know how busy life can be and remembering to give heartworm protection on the same day every month can be a challenge. With Advantage Multi for Dogs, if you forget and go over 30 days between applications, just treat immediately and resume your monthly schedule. Advantage Multi for Dogs also kills adult fleas through contact, meaning they dont have to bite your dog to die. Additionally, the product treats flea infestations as well as 3 common intestinal parasites that infect and harm dogs (roundworms, hookworms, and whipworms). It also treats a very itchy skin mite called sarcoptes, which can infect people.

Advantage Multi for Cats kills adult fleas through contact meaning they dont have to bite and feed on your cat die. It treats flea infestations as well as treats and controls the common occurring ear mite and intestinal parasites roundworms and hookworms. Advantage Multi for Cats prevents also heartworm disease, an often overlooked concern in cats. Additionally, Advantage Multi for Cats is also the first and only FDA-approved product to kill adult fleas, treat flea infestations, and prevent heartworm disease in ferrets.

NOTE: Advantage Multi does not protect against ticks. For additional 8 months of protection against fleas and ticks in dogs and cats, use the Seresto Collar.

For:

Dogs (7 weeks of age or older, weighing 3+ lbs), Cats (9 weeks of age or older, weighing 2+ lbs), Ferrets (weighing 2+ lbs)

Benefits:

  • Easy, once a month topical application
  • Heartworm prevention for dogs that fits your life style. If you forget and go over 30 days between applications, just apply immediately and resume your monthly treatment schedule.
  • Treats and controls circulating microfilaria found in heartworm positive dogs.
  • Kills adult fleas through contact. Fleas dont have to bite your dog or cat to die. Also treats fleas infestations.
  • Treats AND controls roundworms, hookworms, and whipworms in dogs and roundworms and hookworms in cats.
  • Treats AND controls infective ear mites in cats
  • Treats and controls sarcoptic mange in dogs
  • Advantage Multi for Cats is the only FDA-approved flea and heartworm disease prevention product for ferrets
  • Use the Seresto Collar (sold separately) for 8 months of additional protection against fleas, flea eggs, flea larvae, and ticks

How does Advantage Multi work?

Advantage Multi utilizes two effective ingredients, imidacloprid and moxidectin. Moxidectin kills baby heartworms that have been deposited in your dog or cat through the bite of a mosquito, preventing them from growing into adults, migrating to the heart, and causing disease. Moxidectin also kills common intestinal worms by intestinal worms by disrupting nerve transmission resulting in the paralysis and death. Imidacloprid kills fleas through contact. As fleas come in contact with your treated pet, imidacloprid is absorbed through the fleas skin where it acts on the nervous system resulting in spasm and death. Fleas do not need to bite and ingest it through the blood to die like oral treatments require.

Cautions:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become severe, consult a veterinarian immediately. Safety has not been established in breeding, pregnant, or lactating dogs. Not for human use. Keep out of the reach of children. Children should not come in contact with application sites for two (2) hours after application. Causes eye irritation. Harmful if swallowed. Do not get in eyes or on clothing. Avoid contact with skin. Exposure to the product has been reported to cause headache; dizziness; and redness, burning, tingling, or numbness of the skin. Wash hands thoroughly with soap and warm water after handling. If contact with eyes occurs, hold eyelids open and flush with copious amounts of water for 15 minutes. If eye irritation develops or persists, contact a physician. If swallowed, call a poison control center or physician immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by the poison control center or physician. People with known hypersensitivity to benzyl alcohol, imidacloprid or moxidectin should administer the product with caution. In case of allergic reaction, contact a physician. If contact with skin or clothing occurs, take off contaminated clothing. Wash skin immediately with plenty of soap and water. Call a poison control center or physician for treatment advice.

Brand Name:

Advantage Multi (Bayer)

Generic Name:

Imidacloprid, Moxidectin

What is the most important information I should know about Advantage Multi?

Advantage Multi for Dogs is available in the following concentrations; Advantage Multi 9 containing imidacloprid 40 mg and moxidectin 10 mg in 0.4 ml tubes for dogs 3-9 lbs, Advantage Multi 20 containing imidacloprid 100 mg and moxidectin 25 mg in 1 ml tubes for dogs 9.1 to 20 lbs, Advantage Multi 55 containing imidacloprid 250 mg and moxidectin 62.5 mg in 2.5 ml tubes for dogs 20.1-55 lbs, Advantage Multi 88 containing imidacloprid 400 mg and moxidectin 100 mg in 4 ml tubes for dogs 55.1 to 88 lbs, and Advantage Multi 110 containing imidacloprid 500 mg and moxidectin 125 mg in 5 ml tubes for dogs 88.1 to 110 lbs. For dogs over 110 lbs, use the appropriate combination of Advantage Multi for Dogs tubes. Advantage Multi for Cats is available in the following concentrations; Advantage Multi 5 containing imidacloprid 23 mg and moxidectin 2.3 mg in 0.23 ml tubes for cats 2 to 5 lbs, Advantage Multi 9 containing imidacloprid 40 mg and moxidectin 4 mg in 0.4 ml tubes for cats 5.1 to 9 lbs, and Advantage Multi 18 containing imidacloprid 80 mg and moxidectin 8 mg in 0.8 ml tubes for cats 9.1 to 18 lbs. For cats over 18 lbs, use the appropriate combination. Children should not come in contact with the application site for two (2) hours after application.

What should I discuss with my veterinarian before applying Advantage Multi?

Tell your veterinarian if your pet is breeding, pregnant or lactating since safe use of this product in these cases has not been determined. Do not use in pets that are allergic to Advantage Multi or either of the individual ingredients, imidacloprid (Advantage II, K9 Advantix II) or moxidectin.

How should Advantage Multi be applied?

Advantage Multi is applied topically to the skin. It is not given by mouth. Follow the manufacturer's directions for application. Do not apply to irritated skin. Apply each dose once a month, every 30 days. If you do not understand the directions, or if you have difficulty applying the medication, contact your pharmacist or veterinarian. Store Advantage Multi at temperatures between 39 F and 77 F, avoiding excess heat or cold.

What are the potential side effects of Advantage Multi?

If any of the following serious side effects occur, stop using Advantage Multi and seek emergency veterinary medical attention: an allergic reaction (facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma). Contact your veterinarian if your pet shows scratching, rubbing, licking the application site, lethargy, decreased appetite, or hyperactivity. Contact your veterinarian if your pet shows lethargy and prolonged periods of sleep, behavioral changes including agitation, excessive grooming, hiding, pacing, etc., discomfort at the application site (rubbing, scratching, etc.), increased salivation within 1 hour of treatment, increased drinking, or coughing. A medicinal odor and residue at the application site may also be noticed. Ingestion of this product by pets may cause serious adverse reactions including depression, salivation, dilated pupils, incoordination, panting, and generalized muscle tremors. In avermectin sensitive pets, the signs may be more severe and may include coma and death. Hair may appear stiff, matted oily, or damp after application. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Advantage Multi?

Apply the missed dose as soon as you remember. If it is almost time to apply the next dose, skip the missed dose and apply the next dose as directed. Do not apply 2 doses at once.

What happens if I overdose my pet on Advantage Multi?

Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, increased salivation, tremors, or incoordination.

What should I avoid when applying Advantage Multi?

Always follow the dosage instructions provided by your veterinarian. Do not use in dogs under 7 weeks of age or less than 3 lbs. Do not use in cats under 9 weeks of age or less than 2 lbs. Do not use Advantage Multi for Cats in ferrets under 2 lbs. Do not use on pets that are sick, debilitated, or underweight. Do not use Advantage Multi for Dogs on a cat. Do not use Advantage Multi for Cats on a dog. Do not allow any pet to lick the application site for 30 minutes. Separation of treated pets may be necessary. Children should not come in contact with the application site for 30 minutes after application. Advantage Multi can cause eye irritation and be harmful if swallowed. Wash hands thoroughly with soap and water after handling.

What other drugs will affect Advantage Multi?

Talk to your veterinarian or pharmacist regarding any other medications, including vitamins and supplements, as well as other flea and tick products your pet is using.

How to Use
Directions:
  • Advantage Multi for Dogs and Advantage Multi for Cats are prescription medications used for the prevention of heartworm disease.
  • Advantage Multi for Dogs is also used in dogs for the treatment and control of flea infestation, hookworms, roundworms, whipworms, and sarcoptic mange.
  • Advantage Multi for Cats is also used in cats for the treatment and control of flea infestation, roundworms, hookworms, and ear mites.
  • Advantage Multi for Cats is also the first and only approved product to kill adult fleas, treat flea infestations, and prevent heartworm disease in ferrets.
  • Do not use Advantage Multi for Dogs on cats or ferrets.
  • Do not use Advantage Multi for Cats on dogs.
  • Do not administer this product orally.
Application instructions for Advantage Multi for Dogs:
  1. Remove one dose applicator tube from the package. As specified below, administer the entire contents of the Advantage Multi for Dogs tube that correctly corresponds with the body weight of your dog.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. Your dog should be standing for application. Part the hair on the back of your dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of your dog.
Application instructions for Advantage Multi for Cats:
  1. Remove one dose applicator tube from the package. Administer the entire contents of the Advantage Multi for Cats tube.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. FOR CATS: Part the hair on the back of your cat's neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube. FOR FERRETS: Part the hair on the back of your ferret's neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube. NOTE: Only Advantage Multi 9 should be used on ferrets.
Tip:

For the first 30 minutes after application, ensure that dogs and cats cannot lick the product from the application sites on themselves or other treated pets. Separate treated pets from one another and from other pets to reduce the risk of accidental ingestion. Wash hands with soap and water after handling. Do not let children touch the treated pet's skin for at least 30 minutes after applying the product. Do not get these products in your pet's mouth or eyes.

Dosage:
Dogs/Puppies: (7 weeks of age or older)
Weight
Dosage
3-9 lbs
While your dog is standing, apply Advantage Multi 9 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
9.1-20 lbs
While your dog is standing, apply Advantage Multi 20 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
20.1-55 lbs
While your dog is standing, apply Advantage Multi 55 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
55.1-88 lbs
While your dog is standing, apply Advantage Multi 88 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
88.1-110 lbs*
While your dog is standing, apply Advantage Multi 110 for Dogs topically according to the above instructions. Apply each dose once every 30 days.
Cats/Kittens: (9 weeks of age or older)
Weight
Dosage
2-5 lbs
Apply Advantage Multi 5 for Cats topically according to the above instructions. Apply each dose once every 30 days.
5.1-9 lbs
Apply Advantage Multi 9 for Cats topically according to the above instructions. Apply each dose once every 30 days.
9.1-18 lbs**
Apply Advantage Multi 18 for Cats topically according to the above instructions. Apply each dose once every 30 days.
Ferrets:
Weight
Dosage
2-4.4 lbs
Apply Advantage Multi 9 for Cats topically according to the above instructions. Apply each dose once every 30 days.
Horses:
Do not use!
Storage:

Should be stored at room temperature between 39° F and 77° F, avoiding excess heat or cold.

*For dogs over 110 lbs use the appropriate combination.

**For cats over 18 lbs use the appropriate combination.

Ingredients
Advantage Multi 9 for Dogs 3-9 lbs:
Active Ingredients
Amount
Imidacloprid
40 mg
Moxidectin
10 mg
Advantage Multi 20 for Dogs 9.1-20 lbs:
Active Ingredients
Amount
Imidacloprid
100 mg
Moxidectin
25 mg
Advantage Multi 55 for Dogs 20.1-55 lbs:
Active Ingredients
Amount
Imidacloprid
250 mg
Moxidectin
62.5 mg
Advantage Multi 88 for Dogs 55.1-88 lbs:
Active Ingredients
Amount
Imidacloprid
400 mg
Moxidectin
100 mg
Advantage Multi 110 for Dogs 88.1-110 lbs:
Active Ingredients
Amount
Imidacloprid
500 mg
Moxidectin
125 mg
Advantage Multi 5 for Cats 2-5 lbs:
Active Ingredients
Amount
Imidacloprid
23 mg
Moxidectin
2.3 mg
Advantage Multi 9 for Cats 5.1-9 lbs:
Active Ingredients
Amount
Imidacloprid
40 mg
Moxidectin
4 mg
Advantage Multi 18 for Cats 9.1-18 lbs:
Active Ingredients
Amount
Imidacloprid
80 mg
Moxidectin
8 mg
Customer Reviews
Advantage Multi is rated 4.2 out of 5 by 283.
Rated 4 out of 5 by from I have been using this for more than a year and find it very convenient and was recommended by my vet as my senior dog has an immune issue so have to be careful with what we use.
Date published: 2017-12-10
Rated 4 out of 5 by from Great product I use to use revolution and was having to buy 2 separate products due to the fact that one of my cats was out of the weight range of the other one this covers both and so far I’ve had no isssues with the product I would recommend to anyone who has 2 cats that weigh differently (Maine coons tend to get very big weighing in at 18.3lbs ) very pleased
Date published: 2017-12-03
Rated 4 out of 5 by from I have never seen even ONE flea on any of my dogs i do like the convenience of dual protection against heartworm & fleas. but it's messy, I put it on them first thing in the morning so it's not still messy by bedtime. I have 3 small dogs & 1 cat.
Date published: 2017-12-01
Rated 3 out of 5 by from Still works great, but becoming less good value Been using this on my two cats for about a year now, better than others as it is multi protection, however the list it covers has decreased from 7 to 5 and the pack quantity is also smaller. price remains the same though.
Date published: 2017-11-14
Rated 5 out of 5 by from Best product I've been dealing with 1800PETMEDS since I adopted my Lilly girl. This product is amazing and has kept her healthy ever since. They are a pleasure to deal with as well.
Date published: 2017-11-01
Rated 5 out of 5 by from Flea Free and still Purring ! This product is veterinarian approved and really works for my cat family. The multi formula treats each of them for fleas, heart worm, ear mites, hookworms and roundworm with no side effects. The treatment lasts, for my cats, up to 6 weeks.
Date published: 2017-10-21
Rated 5 out of 5 by from Only product that keeps our greyhound worm free We adopted a greyhound a few years ago and like most greys from the track, had a very bad doubt with hookworms. We would kill them off with a dewormer, and they would come right back even with her preventatives. We tried two different kinds of oral preventatives before we were suggested Advantage Multi. I wish there had been more information of people with similar experiences so our girl could have been well sooner.
Date published: 2017-10-19
Rated 5 out of 5 by from A bit pricey but worth it. Seems to work where other's don't.
Date published: 2017-10-14
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Q&A

Is 1800 Petmeds a Vet-VIPPS accredited pharmacy?

Asked by: Tami4
Thank you for your question. The Vet Vipps program was discontinued and replaced with DOT Pharmacy accreditation. We are accredited per the National Association of Boards of Pharmacy , you may view the link https://www.1800petmeds.com/dotpharmacy.jsp for more information or give us a call at 1-800-738-6337.
Answered by: Crystal PetMed Pro
Date published: 2017-12-11

What can I expect regarding killing of/treatment for lice on my dog?  I applied product last night on infected dog, how long does it take to kill the lice?

Asked by: Darc
Thank you for your question. The initial treatment will kill the adult lice. However, nits are not susceptible to insecticides and will remain on the pet. Treatment every 1 to 2 weeks for at least 4 weeks should be sufficient to kill all hatched nymphs.
Answered by: Crystal PetMed Pro
Date published: 2017-11-28

Do I need a Dr.s prescription?

Asked by: Loren
Thank you for your question. Advantage Multi does require a veterinarians prescription.
Answered by: Crystal PetMed Pro
Date published: 2017-11-06

Does your company accept care credit?

Asked by: Betty
Thank you for your question. Unfortunately we do not accept care credit at this time.
Answered by: Crystal PetMed Pro
Date published: 2017-10-24

 Hi, Do you have the one for kittens under 5.1 pounds, I don’t see it. Please let me know, and I will buy a six pack... I was looking forward to the 15% off tonight, plus the free shipping this time :-) Thank you! 

Asked by: Feralcat101
Thank you for your question. Unfortunately we do not offer the Advantage Multi for cats under 5.1lbs at this time.
Answered by: Crystal PetMed Pro
Date published: 2017-10-17

Will advantage multi kill fleas on animal and their bedding?

Asked by: bev03
Advantage Multi utilizes two effective ingredients, imidacloprid and moxidectin. Moxidectin kills baby heartworms and common intestinal worms. Imidacloprid kills fleas through contact. As fleas come in contact with your treated pet, imidacloprid is absorbed through the fleas skin where it acts on the nervous system resulting in spasm and death. Fleas do not need to bite and ingest it through the blood to die like oral treatments require.
Answered by: Lisa M
Date published: 2017-10-13

Can I purchase this on a 3 month supply? And how much'would that be and do I need a prescription from my vet?

Asked by: Manny
We only carry Advantage Multi in a 6 pack which is a 6 month supply.
Answered by: Lisa M
Date published: 2017-10-30

Does Advantage Multi for dogs kill both the larval as well as the mature hookworms?

Asked by: Denise
Advantage Multi kills adult fleas, treats flea infestations as well as 3 common intestinal parasites(roundworms, hookworms, and whipworms). It is a larvicidal which means it kills flea larvae.
Answered by: Lisa M
Date published: 2017-09-14
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