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Apoquel Chewable
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17 Questions Answered
$2.98
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What is Apoquel Chewable?
Apoquel Chewable is a prescription item used to treat and control itching and inflammation in dogs resulting from a variety of causes, including flea allergy, food allergy, contact allergy and atopic dermatitis. Apoquel delivers onset of relief within 4 hours. It effectively controls itching within 24 hours. Apoquel requires a prescription from your veterinarian, and is sold per chewable tablet in strengths of 3.6 mg, 5.4 mg, or 16 mg.
Suitable For:
Dogs over 12 months in age and weighing more than 6.6 lbs.
Benefits:
- Provides effective relief within 4 hours
- Effectively controls itch within 24 hours
- Safe for short term and long term usage
- Can be used along with many other common medications, including parasiticides, antibiotics, and vaccines
- Uniquely targeted to stop the itch with minimal negative impact on immune function
- Controls pruritus associated with allergic dermatitis and controls atopic dermatitis
- Sold per tablet
How does Apoquel Chewable work?
Apoquel is a selective janus kinase (JAK) inhibitor, which targets pruritogenic (itch creating) cytokines. It effectively controls itching due to food allergies, flea allergies, contact dermatitis, and atopic dermatitis. Apoquel works to control pruritus for fast-acting relief, and provides significant short-term and long-term reduction of itching and inflammation.
Cautions:
IMPORTANT SAFETY INFORMATION: Do not use Apoquel or Apoquel Chewable in dogs less than 12 months of age or in dogs with skin infections. Apoquel Chewable may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. Clinical studies and post-approval evaluations identified both benign and malignant neoplastic conditions. Apoquel Chewables have not been evaluated for use alongside certain medications, including those frequently prescribed for skin conditions (like corticosteroids and cyclosporine.) Avoid using in dogs that are breeding, pregnant, or nursing. Common side effects include vomiting and diarrhea. Apoquel Chewables can be used safely alongside many common medications such as including parasiticides, antibiotics, topical products for bacterial skin infections, and vaccines.
Brand Name
Apoquel
Generic Name
oclacitinib (ah-clas-eh-tee-nib)
Manufacturer:
Zoetis
What is the most important thing I should know about Apoquel Chewable?
Apoquel Chewable is used to relieve itching and inflammation caused by a variety of diagnoses, including allergic dermatitis and atopic dermatitis.
What should I discuss with my veterinarian before giving Apoquel Chewable to my pet?
Tell your veterinarian if your pet has ever had an allergic reaction to the medication.
How should Apoquel Chewable be given?
The dose of Apoquel Chewables is 0.18 to 0.27 mg/lb of body weight. See Apoquel Chewable Dosage Chart.
What are the potential side effects of Apoquel Chewable?
Apoquel Chewable may increase susceptibility to infection, including demodicosis. It may also exacerbate neoplastic conditions. Adverse reactions reported in a masked field study included diarrhea, vomiting, anorexia, new cutaneous or subcutaneous lumps, profuse salivation, and lethargy. In most cases, diarrhea, vomiting, anorexia, and lethargy spontaneously resolved with continued dosing. Contact your veterinarian if you see abnormal skin changes, dermal lumps, or growths after your dog has consumed Apoquel.
What happens if I miss giving a dose of Apoquel Chewable?
Give the missed dose with food as soon as you remember and resume a regular dosing schedule.
What happens if I overdose my pet on Apoquel Chewable?
Contact your veterinarian immediately for medical attention, or visit your closest emergency animal hospital..
What should I avoid while giving Apoquel Chewable to my pet?
Apoquel Chewable should not be given to dogs younger than 12 months or those with serious infections. Apoquel Chewable should not be used in breeding, pregnant or lactating dogs. Apoquel Chewable usage has not been evaluated in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents. Dogs taking Apoquel Chewables should be monitored for any developing harmful side effects and infections, including demodicosis and neoplasia.
What other drugs will affect Apoquel Chewable?
Talk to your veterinarian before giving any prescription or over the counter medications.
Apoquel Chewable Directions:
- Administer to your dog orally in convenient twice-daily doses for up to 14 days according to the weight chart below, then administered once daily for a maintenance dose.
Tip:
Apoquel Chewable may be administered with or without food
Apoquel Chewable Dosage Chart:
| Weight | Amount |
|---|---|
| 6.6-9.9 lbs | 1/2 of a 3.6 mg chewable tablet twice daily for up to 14 days |
| 10-14.9 lbs | 1/2 of a 5.4 mg chewable tablet twice daily for up to 14 days |
| 15-19.9 lbs | One 3.6 mg chewable tablet twice daily for up to 14 days |
| 20-29.9 lbs | One 5.4 mg chewable tablet twice daily for up to 14 days |
| 30-44.9 lbs | 1/2 of a 16 mg chewable tablet twice daily for up to 14 days |
| 45-59.9 lbs | Two 5.4 mg chewable tablets twice daily for up to 14 days |
| 60-89.9 lbs | One 16 mg table twice daily for up to 14 days |
| 90-129.9 lbs | 1 1/2 16 mg chewable tablets twice daily for up to 14 days |
| 130-175.9 lbs | Two 16 mg chewable tablets twice daily for up to 14 days |
| Weight | Amount |
|---|---|
| 6.6-9.9 lbs | 1/2 of a 3.6 mg chewable tablet once daily |
| 10-14.9 lbs | 1/2 of a 5.4 mg chewable tablet once daily |
| 15-19.9 lbs | One 3.6 mg chewable tablet once daily |
| 20-29.9 lbs | One 5.4 mg chewable tablet once daily |
| 30-44.9 lbs | 1/2 of a 16 mg chewable tablet once daily |
| 45-59.9 lbs | Two 5.4 mg chewable tablets once daily |
| 60-89.9 lbs | One 16 mg table once daily |
| 90-129.9 lbs | 1 1/216 mg chewable tablets once daily |
| 130-175.9 lbs | Two 16 mg chewable tablets once daily |
| Cats |
|---|
| Do not use! |
| Horses |
|---|
| Do not use! |
Ingredients in Apoquel Chewable Tablets:
| Active Ingredient | Amount |
|---|---|
| Oclacitinib maleate | 3.6 mg |
| Active Ingredient | Amount |
|---|---|
| Oclacitinib maleate | 5.4 mg |
| Active Ingredient | Amount |
|---|---|
| Oclacitinib maleate | 16 mg |
LEARN MORE ABOUT
Customer Reviews
Q&A
Apoquel Chewable is the first and only chewable treatment that relieves allergic itching in dogs. The treat-like formula simplifies dosing to eliminate the stress and challenges of giving your pet medications.
Relief Pet Owners Can Count On
Apoquel Chewable
provides effective control
of itching associated with allergies within 12-24 hours.1
Tasty pork liver-flavored chewables designed to be as delicious as a treat. A recent study found that over 90% of dogs ate Apoquel Chewable voluntarily.2
Safe to use for long-term maintenance or short-term therapy3,4 in dogs 12 months of age and older.
Why Does Apoquel Lead The Pack?
Apoquel Chewable stops allergic itch right at the source.5
- Antihistamines offer little or no benefit in treating flare-ups in a majority of dogs with allergic itch.6
- Steroid based treatments may offer relief but may not be a good option if your dog requires long-term treatment
- Home remedies, such as, topicals, may provide some temporary relief but don’t treat the underlying cause of allergic itch.
Indications
Controls pruritus (itching) associated with allergic dermatitis and atopic dermatitis in dogs over 12 months of age.
REFERENCES
1. Data on file: Study Report A161C-US-21-C02, Zoetis Inc., 2022.
2. Visser M, Walsh K, King V, Sture G, Caneva L. Acceptance of oclacitinib maleate(Apoquel) chewable tablets in client-owned dogs with allergic and atopic dermatitis. BMC veterinary research. 2022;18(1):103. doi:10.1186/s12917-022-03210-x
3. Cosgrove SB, Wren JA, Cleaver DM, et al. Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. Vet Dermatol. 2013;24(5):479- e114. doi: 10.1111/vde.12047.
4. Cosgrove SB, Cleaver DM, King VL, et al. Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Vet Dermatol. 2015;26(3):171-179, e35. doi: 10.1111/vde.12194.
5. Gonzales AJ, Bowman JW, Fici GJ, et al. Oclacitinib (APOQUEL(®) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Journal of Veterinary Pharmacology and Therapeutics. 2014;37(4):317-324. doi:10.1111/vp.12101.
6. Olivry T, DeBoer DJ, Favrot C, et al. for the International Committee on Allergic Diseases of Animals. Treatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA). BMC Vet Res. 2015;11:210. doi: 10.1186/s12917-015-0514-6.
Controls pruritus (itching) associated with allergic dermatitis and atopic dermatitis in dogs over 12 months of age.
REFERENCES
1. Data on file: Study Report A161C-US-21-C02, Zoetis Inc., 2022.
2. Visser M, Walsh K, King V, Sture G, Caneva L. Acceptance of oclacitinib maleate(Apoquel) chewable tablets in client-owned dogs with allergic and atopic dermatitis. BMC veterinary research. 2022;18(1):103. doi:10.1186/s12917-022-03210-x
3. Cosgrove SB, Wren JA, Cleaver DM, et al. Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. Vet Dermatol. 2013;24(5):479- e114. doi: 10.1111/vde.12047.
4. Cosgrove SB, Cleaver DM, King VL, et al. Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Vet Dermatol. 2015;26(3):171-179, e35. doi: 10.1111/vde.12194.
5. Gonzales AJ, Bowman JW, Fici GJ, et al. Oclacitinib (APOQUEL(®) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Journal of Veterinary Pharmacology and Therapeutics. 2014;37(4):317-324. doi:10.1111/vp.12101.
6. Olivry T, DeBoer DJ, Favrot C, et al. for the International Committee on Allergic Diseases of Animals. Treatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA). BMC Vet Res. 2015;11:210. doi: 10.1186/s12917-015-0514-6.
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