What is Primor?
Primor (sulfadimethoxine/ormetoprim) is a broad-spectrum antibiotic combination used to treat susceptible bacterial infections in dogs. Primor is sold per tablet and requires a prescription from your veterinarian.
- Treats skin and soft tissue infections (wounds and abscesses)
- Also effective against urinary tract infections caused by susceptible bacteria
- Single, comparatively low dose provides rapid and sustained therapeutic blood levels
- Sold per tablet
How does Primor work?
Primor is made up of two antibiotics: sulfadimethoxine and ormetoprim. Together, these antibiotics are even more powerful than when they are used alone, as they block two sequential steps in bacterial folic acid synthesis. The net effect is not only the limiting of bacterial growth, but the killing of bacteria as well.
Do not use in pregnant or nursing pets. Your pet should be encouraged to drink plenty of water while being given Primor. Before giving Primor, be sure to tell your veterinarian what other medications or treatments your pet is receiving.
Primor Tablets (Pfizer Animal Health)
What is the most important thing I should know about Primor?
Primor is a potentiated sulfa drug used in dogs for the treatment of skin and soft tissue infections (wounds and abscesses), and urinary tract infections caused by susceptible bacteria. Primor may also be used for other conditions not listed.Primor is a prescription medication FDA-approved for veterinary use in dogs. Primor is available as scored tablets in two strengths: Primor 240 which contains 200 mg sulfadimethoxine and 40 mg ormetoprim, and Primor 1200 which contains 1000 mg sulfadimethoxine and 200 mg ormetoprim. Primor is not for use in pets allergic to it or other sulfa drugs.
What should I discuss with my veterinarian before giving Primor to my pet?
Tell your veterinarian if your pet is allergic to Primor or other sulfonamides (sulfa drugs). Tell your veterinarian if your pet has liver disease or blood dyscrasias, is dehydrated, or is pregnant or lactating. Also tell your veterinarian what other medication, including vitamins and supplements, that you are giving your pet while giving Primor.
How should Primor be given?
The usual initial starting dose is 25 mg/lb on the first day of treatment followed by 12.5 mg/lb given once a day. Treatment should continue for 2 days after symptoms disappear. However, treatment should not exceed 21 consecutive days. Give Primor by mouth. It may be given with food. Leave plenty of water for your pet to drink. Always follow the dosage instructions provided by your veterinarian. Do not give Primor to any pet other than the pet for whom it was prescribed. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. Store Primor at room temperature in a tight, light-resistant container. Keep this medication away from children and pets.
What are the potential side effects of Primor?
Sulfa crystals may appear in your pet's urine. Your pet should be allowed to drink plenty of water while taking this medication. Other side effects that may occur include KCS or dry eye, anemia, fever, loss of appetite, vomiting or diarrhea, joint inflammation, kidney damage, or skin rash. Stop the medication and contact your veterinarian if any of the above symptoms occur. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet. If your pet experiences an allergic reaction, signs may include facial swelling, hives, scratching, and sudden onset of diarrhea, vomiting, shock, seizures, or coma. If these signs occur, contact your veterinarian immediately.
What happens if I miss giving a dose of Primor?
Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.
What happens if I overdose my pet on Primor?
Seek emergency veterinary medical treatment. Symptoms of overdose may include side effects listed below and may also include behavioral changes.
What should I avoid while giving Primor to my pet?
Antacids may decrease the effectiveness of sulfa drugs such as Primor. Give antacids 2-3 hours before or after giving a dose of Primor.
What other drugs will affect Primor?
Before giving Primor, tell your veterinarian if your pet is being given methotrexate, warfarin, phenylbutazone, thiazide diuretics, aspirin, probenecid, or phenytoin.
- Primor is a prescription medication used in dogs for the treatment of skin and soft tissue infections (wounds and abscesses), and urinary tract infections caused by susceptible bacteria.
- Pets should be encouraged to drink plenty of water while being given Primor. Primor may be given with food.
If your pet shows no improvement after 2 or 3 days, have your veterinarian re-evaluate your pet's diagnosis. Treatment should not exceed 21 consecutive days.
The initial dose is 25 mg/lb of pet's body weight on the first day of treatment followed by 12.5 mg/lb of pet's body weight given once a day thereafter. Treatment should continue for at least 2 days after symptoms disappear.
Store this medication at room temperature away from moisture and heat.
Primor is rated
Rated 5 out of
No side effects
We are day ten into UTI treatment. No problems for 10 week old female Rottweiler. Happy active puppy with good appetite. We also had bladder relaxer for first three days. And UTI is white cell elevated based, not Nitrates
Date published: 2017-08-04
Rated 3 out of
My dog is using the Primor 600 Mg. It has caused a loss of appetite. She usually has a good appetite. Also I noticed some of the rash from the skin infection is still there and will call my doctor today. So far she has been on it for 7 days.
Date published: 2014-09-22
Rated 5 out of
I am using this for a second time in 4 months to treat diarrhea/bowel incontinence in my 8 year old malti-poo. The vet thinks she might have been suffering from a bacterial overload, and both times this has cleared up the symptoms quickly, with no side effects.
Date published: 2014-01-18
Rated 5 out of
Primore only med to help uti.
My Pittie had a chronic uti for months with no reliefe from other antiboditics. Primor is the only med strong enough that has cleared up the uti issue for my dog. I would definitely use again because I have tried everything else.
Date published: 2013-04-18
Rated 4 out of
My 2 year old dog had a bacterial infection from scratching due to dermatitis. My vet prescribed this for him to take 12 days. He had no side effects and is back to his normal self. I did ask my vet questions about the medicine when given to me though. After all, he is my kiddo and I wanted to be sure of everything before administering it to him.
Date published: 2013-03-22
Rated 1 out of
I do not recommend
My shepherd mix was given this for her respiratory issues a couple of years ago. A couple of days into the medication she had a seizure and fell off of the couch. I stopped the medicine at once and she has never had a seizure since then. There are other medications that can be given in place of this that I feel do the job better and are a lot less dangerous!
Date published: 2012-03-29
Rated 1 out of
STAY AWAY FROM PRIMOR
I have six schnauzer's. The first time I used primor on one of my schnauzer's it was used to prevent bladder stones. My poor girl developed dry eye that they say may never clear completely. She may have to have surgery to treat this. Another one of my girls was given Primor for a bladder infection. She developed nausea and diarhea(with severe bleeding) and refused to eat for six days and was severely dehydrated. She is 12 years old, and I thought for sure I was going to lose her. She is FINALLY doing better, but now I am having trouble getting her weight back up. I will NEVER use Primor again. As far as I am concerned it should be outlawed.
Date published: 2011-12-28
Rated 1 out of
Primor caused my dog to Shake and was Scared! :(
My poor Maltese, who is 6 yrs old had bladder surgery to remove a stone. 2 weeks after surgery he continue to have urges to urine. Took him to the Vet and they gave him Primor to address a new UTI. The first Dose was strong (2 tablets, 240 each). NEVERA AGAIN! My dog reacted so strange to it . My husabnd went to kiss him and he jumped out of his skin. He was shaking like a leaf. Walking around the house with his tail down. Ended up going to the emergency. They gave him a Valium IV to calm him down and had a fever of 102.9.....AWEFUL EXPERIENCE! The E.R Vet said this is an OLD Drug with too many side effects. He informed us that the newer drugs don't have as many side effect........My little guy was freaked out! I thought something was going to happen. What a scary experience! Becareful--I would hate for your dog to experience the same thing!
Date published: 2011-05-08