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Adequan for Dogs

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$192.36 $134.99 
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100 mg/ml 2 x 5 ml Vials
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$192.36 $134.99 
Ships in one business day or less

Step 1. Select an Option:

100 mg/ml 2 x 5 ml Vials
Price w/coupon SAVE20
Free Shipping
You save $57

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Product Info

What is Adequan Canine?

Adequan Canine (for dogs) is used to control symptoms associated with degenerative or traumatic arthritis. It is an injectable polysulfated glycosaminoglycan (PSGAG) and is the only FDA approved product of its type. Adequan has been clinically shown to help treat the disease while giving relief from pain. It modifies the disease cycle, stimulates cartilage repair processes and diminishes joint damage while reducing the pain caused by osteoarthritis. Adequan requires a prescription from your veterinarian. A syringe is needed, but not included in the package.




  • Helps control noninfectious degenerative or traumatic arthritis
  • Good for postsurgery treatment
  • Starts to work within hours and stays in the joint for about three days

How does Adequan Canine work?

Adequan inhibits enzymes that break down cartilage within your dog's joints. It reduces inflammation and increases the thickness of joint (synovial) fluid.


Not for use in humans. Do not give this medication to breeding, pregnant, or lactating pets. Use with caution in pets with kidney or liver disease, or bleeding disorders.

Brand Name:

Adequan (Manufactured by Luitpold)

Generic Name:

Polysulfated Glycosaminoglycan (PSGAG) Solution

What should I discuss with my veterinarian before giving Adequan Canine?

Tell your veterinarian if your dog has any known or suspected bleeding disorders. Tell your veterinarian if your dog has any liver or kidney disease. Tell your veterinarian if your dog is breeding, pregnant or lactating.

How should Adequan Canine be given?

Give this medication exactly as directed by your veterinarian. Adequan is given by intramuscular (IM, into the muscle) injection. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. If you have difficulty giving the medication, contact your veterinarian. Store Adequan at 68 - 77 F (20 - 25 C) excursions permitted to 59 - 86 (15 - 30 C). Keep this medication out of the reach of children and pets.

What are the possible side effects of Adequan Canine?

Few side effects are seen following Intramuscular injection. Stop giving Adequan and seek emergency veterinary medical attention if an allergic reaction (facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma) should occur. Bleeding from the nose, blood in the feces, or dark and tarry stools may indicate a decreased ability of blood to clot. Contact your veterinarian if you notice these symptoms. Other side effects may also occur. Talk to your veterinarian about any side effects that seem unusual or bothersome to your pet.

What happens if I miss giving a dose of Adequan Canine?

Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication.

What should I avoid while giving Adequan Canine?

Do not give this medication to breeding, pregnant or lactating animals. Use with caution in animals with kidney or liver disease, or blood clotting or coagulation disorders.

What other drugs will affect Adequan Canine?

Consult your veterinarian before using any other prescription or over the counter medicines including vitamins and supplements.

How to Use

Adequan for Dogs Directions:

  • Adequan is a prescription medication used in dogs for the control of signs associated with non-infectious degenerative and/or traumatic arthritis of canine synovial joints and following surgical procedures involving a joint.

Do not give this medication to breeding, pregnant, or lactating animals. Use with caution in animals with kidney or liver disease, or blood clotting or coagulation disorders.

Adequan for Dogs Dosage for Dogs:

All weightsInject 2 mg per lb of body weight given only by intramuscular (IM) injection twice a week for up to 4 weeks (a maximum of 8 injections)
Adequan for Dogs Dosage for Cats:
Do not use!
Adequan for Dogs Dosage for Horses:
Do not use!

Store Adequan at 68° - 77° F (20° - 25° C) excursions permitted to 59° - 86° (15° - 30° C). Keep this medication out of the reach of children and pets.


Adequan Ingredients:

Adequan (for Dogs)
Active IngredientsAmount
Polysulfated Glycosaminoglycan100 mg
Benzyl alcohol (a preservative)0.9% v/v
Other Ingredients: Sodium hydroxide and/or hydrochloric acid added when necessary to adjust pH. Sodium Chloride may be added to adjust tonicity.
Customer Reviews
Adequan for Dogs is rated 4.7 out of 5 by 117.
Rated 5 out of 5 by from A Miracle Drug My dog has arthritis in most joints in her body, including her spine. She was so crippled before the Adequan, but now she walks and runs with no problem at all. She started out getting injections twice a week. Now all it takes to keep her in good shape is an injection every two weeks. I couldn't be happier for her.
Date published: 2018-01-07
Rated 5 out of 5 by from Visible Improvement My veterinarian daughter recommended Adequan for my 13 year old standard poodle who was having difficulty walking and getting up to standing position. It was like a miracle for her. She improved significantly and actually plays with the other dogs instead of sleeping all day. Her pain is significantly decreased.
Date published: 2018-01-01
Rated 5 out of 5 by from No cons to this Our 6 year old boxer mix was diagnosed with spondylosis and our vet recommended this instead of pain meds. We just started his loading doses and amazingly seeing positive changes in his behavior.
Date published: 2017-12-12
Rated 5 out of 5 by from Adequan When my vet wa discussing Adequan for my senior pit who has always had issues with hip dysplasia, subluxated knee cap and now arthritis, I have to admit I was skeptical. But after about 2 weeks she has become a completely new dog. Moving MUCH more easily, with energy and what seems like a lot less pain. Well worth the expense.
Date published: 2017-11-19
Rated 5 out of 5 by from Extra mobility for dysplasia My 5yr old Rott/GSD mix has hip dysplasia with arthritis. The Adequan injection every two weeks has kept her moving without so much pain. (She takes a pain med and supplements as well and the combination works great)
Date published: 2017-10-24
Rated 5 out of 5 by from Wonder drug for aging pets I've used Adequan Injectable on my horses in the past with very good results. After trying many oral supplements and anti-inflammatory drugs on my 11 yr old Golden Retriever Maggie I figured why not Adequan for her too? We just finished our "loading dose" protocol and will now do our once a month injection for a few months. I already see a HUGE difference in her!!! She's now able to jump up onto the couch and her favorite chair again without help. She's running and playing fetch and racing around with her 2 yr old sister Lily. She's brighter and wagging her tail all the time again. I have my youngster back again!!! Golden's remain young at heart for life. Why not keep their bodies right there too? I HIGHLY recommend Adequan Canine to anyone in a similar situation.
Date published: 2017-07-31
Rated 5 out of 5 by from Really great product. I have been using Adequan for awhile now for my dog and I can't believe the effectiveness of it. She went to crying when she walked to running with me on the trails again.
Date published: 2017-07-29
Rated 5 out of 5 by from our vet had told us last summer that if this medication didn't work we would have to make a decision for Stormy.She is loaded with arthritis in her back and hips and could barely move. Adequan literally turned back the clock for her! Without it we wounld be Stormy-less. Awesome results!
Date published: 2017-07-25
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Do you sell one-vial packages of adequan?  I need a smaller quantity because my dog is on maintenance now.  If I bought 2 vials, the second vial would no longer be good after its May 2018 expiration date.

Asked by: Paula
We carry Adequan in a 2x5 ml vial box. We do not sell single vials.
Answered by: Lisa M
Date published: 2018-01-02

After 8 injections, how long should a dog be off before starting treatment (8 injections) again?

Asked by: 4misst
Your veterinarian will determine the duration of treatment based on your pet's condition and response to the drug.
Answered by: Lisa M
Date published: 2017-12-30

My 57 English bulldog just had TPLO surgeries on both knees. Ortho recommen Adequan. I’m confused about the dosage, how much would she need? 

Asked by: Lauren
The recommended dose of Adequan is 2 mg per lb of body weight given twice a week for up to 4 weeks (a maximum of 8 injections). Your veterinarian, however, will determine the appropriate dose for your pet's condition.
Answered by: Lisa M
Date published: 2017-12-27

Gave Adequan years ago per ortho vet. We did subdural not IM. Dog is 80 pounds. How many doses will I get out of one box?

Asked by: Carolbh
Thanks for your question. A single dose for your dog would be 160 mg (1.6 mL). One box would be enough for 6 doses total. This medication is to be given twice weekly for up to 4 weeks. I hope this is helpful!
Answered by: Adriane
Date published: 2017-12-04

I have a 150lb many viles would we need if he needs 2 injections per week for the first month?

Asked by: shedaisy0505
Hello, Thanks for your question. The volume to inject for your dog will be 3 mL intramuscularly twice weekly. You will need to purchase 5 vials of adequan to last 4 weeks. Currently we sell a package of Adequan that contains 2 vials, so you will need to purchase 3 of the packages.
Answered by: Adriane
Date published: 2017-11-27

when does this batch expire?

Asked by: utell
The expiration date for the Adequan that we currently have in stock is 5/2018.
Answered by: Lisa M
Date published: 2017-10-16

Can you only inject one area at a time?  My lab has severe arthritis and the vet says we will need to alternate injections each time (i.e. Left and right leg).  Can you not do multiple injections?

Asked by: WabiSabi
Adequan is usually injected in one site for each dose. Alternating injection sites is recommended. Consult your veterinarian for the best way to administer Adequan to your pet.
Answered by: Lisa M
Date published: 2017-09-21

What is the maintenance dose for long term use?

Asked by: Tony
We have had good results doing 4 weekly injections then going to monthly which is how our naturopathic vet suggested it be used
Answered by: Xanadulady
Date published: 2017-09-15
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