Skip to Main Content ›
FREE Shipping on orders over $49
20% OFFCoupon Code:
SAVE20
100% Satisfaction Guaranteed
 20% OFF w/code
SAVE20
FREE Shipping $49+
100% Satisfaction Guaranteed
My Account
Errors:

Acepromazine

1. We'll ask for your vet's info during checkout.
2. We verify your prescription and ship your order!
Close
Starts $0.69 $0.46 per tablet
Ships in one business day or less

Step 1. Select a Tablet Size:

10 mg Tab (per tablet)
$0.69
$0.58
$0.46
Price w/coupon SAVE20
25 mg Tab
$1.25
$1.06
$0.85
Price w/coupon SAVE20
Starts $0.69 $0.46 per tablet
Ships in one business day or less

Step 1. Select a Tablet Size:

10 mg Tab (per tablet)
$0.69
$0.58
$0.46
Price w/coupon SAVE20
25 mg Tab
$1.25
$1.06
$0.85
Price w/coupon SAVE20

Step 2. Select a Quantity:

-
+
Please select all product options.

Step 2. Enter Quantity:

Please select all product options.
Product Info

What is Acepromazine?

Acepromazine is a phenothiazine tranquilizer that is used prior to anesthesia and surgery because of its sedative effects and its ability to prevent vomiting. It's also used as an aid in controlling excited animals during examinations, treatments, and grooming. Acepromazine is sold per tablet and requires a prescription from your veterinarian.

For:

Cats and Dogs

Benefits:

  • An effective tranquilizer
  • Controls overly excitable animals
  • Can prevent vomiting post surgery
  • Sold affordably per tablet

How does acepromazine work?

Acepromazine is classified as a phenothiazine neuroleptic, which means it modifies the chemicals in your pets brain to change their behavior. Its a tranquilizer that depresses the central nervous system. The mechanism of action is not exactly known, however, its thought to block receptors of dopamine in the brain, a chemical used for cell-to-cell communication.

Cautions:

Tell your veterinarian if your pet has liver disease, heart disease, seizure disorders or if the pet is pregnant or lactating. Also mention other CNS medications, such as Phenobarbital, that your pet may be taking.

Brand Name:

Aceproject (Vetus), Aceprotabs (Vetus), PromAce (Fort Dodge)

Generic Name:

acepromazine (ace PRO ma zeen)

What is the most important information I should know about acepromazine:

Acepromazine is a prescription medicine FDA approved for veterinary use in dogs only; however it is a commonly accepted practice for veterinarians to use acepromazine in cats. Acepromazine is available as 10 mg and 25 mg tablets. Each tablet is quarter scored. The usual dose for dogs and cats is 0.25-1 mg/lb. Acepromazine may color the urine pink. Occasionally, this medication may have an opposite effect causing stimulation, therefore this medication should not be used to treat aggression.

What should I discuss with my veterinarian before giving acepromazine to my pet?

Tell your veterinarian if your pet has liver disease, heart disease, seizure disorders, or if the pet is pregnant or lactating. You should also mention other CNS (Central Nervous System) medications such as clomipramine, fluoxetine, and Reconcile or monoamine oxidase inhibitors such as Anipryl, Selegiline, or Preventic Collar that you are giving or using on your pet.

How should acepromazine be given?

Give acepromazine exactly as directed by your veterinarian. Acepromazine should be given 45 minutes to 1 hour prior to the procedure for the medication to take effect. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you.

What are the potential side effects of acepromazine?

Stop giving acepromazine and seek emergency veterinary medical care in the event of rare allergic reaction (difficulty breathing; swelling of the lips, tongue, or face; hives). Other, less serious side effects that have been reported but may resolve with continued treatment. Continue to give acepromazine and notify your veterinarian if your pet shows signs of sedation, depression, incoordination, low blood pressure, slower heart rate and breathing. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of acepromazine?

Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose my pet on acepromazine?

Seek emergency veterinary medical treatment. Symptoms of overdose may include excess drowsiness, slow heart rate and breathing, unsteady movement, unconsciousness, low blood pressure or seizures.

What should I avoid while giving acepromazine to my pet?

Do not give your pet epinephrine or CNS depressant medications such as Phenobarbital.

What other drugs will affect acepromazine?

Before giving acepromazine, tell your veterinarian if your pet is being given phenytoin, antiarrhythmics such as quinidine and beta blockers such as propranolol. Antidiarrheal medications and antacids may reduce the effectiveness of acepromazine.

How to Use

Acepromazine Directions:

  • Acepromazine is a prescription tranquilizer use by veterinarians in dogs and cats.
  • Acepromazine is typically used prior to anesthesia and surgery because of its sedative effects and because it can prevent vomiting.
  • It is also used as an aid in controlling excited animals during examination, treatment, and grooming.
Tip:

Acepromazine may color the urine pink. Occasionally, this medication may have an opposite effect causing stimulation; therefore this medication should not be used to treat aggression.

Dosage:
Dogs/Cats:
Weight
Dosage
All weights
Give 0.25-1 mg/lb of pet's body weight by mouth. Should be given 45 minutes to 1 hour prior to the procedure
Horses:
Do not use!
Storage:

Should be stored at room temperature. Keep away from moisture and heat.

Ingredients

Acepromazine Ingredients:

Acepromazine 10 mg tablets:
Active Ingredient (per tablet)
Amount
Acepromazine Maleate
10 mg
Acepromazine 25 mg tablets:
Active Ingredient (per tablet)
Amount
Acepromazine Maleate
25 mg
Customer Reviews
Acepromazine is rated 4.1 out of 5 by 74.
Rated 4 out of 5 by from Slow acting but little side effects My 12 year old bichon has car anxiety, fireworks anxiety and severe allergies. I find this product makes him sleepy which helps in the car, and when there are fireworks. Since i don't like giving him prednisone based products for scratching, ocassionally a half a tablet aids his sleeping stops scratching at night.
Date published: 2017-10-01
Rated 5 out of 5 by from Helped Our Petrified Pup We rescued a 3 yr old yorkie/corgi mix about a year ago. He'd been in the wild for what they guessed was "over a year" according to the shelter. He's transformed into an incredible dog around our house, receives, and gives, lots of love. But outside our home, around strangers, or specifically car rides, Katy bar the door. The poor little guy is the most terrified animal, or person, I've ever witnessed. He starts hyperventilating, trembling, and just totally loses control of his faculties. He's thrown up in the car on 10 minute rides. We've tried thunder shirts, homeopathic medicine's, and behavior training. The ONLY medication we found that helps for long car rides is ace promazine. While he was still nervous on the three hour car ride, he roamed from front to back and looked out the windows (a first, instead of hiding under the backseat per usual). He did not throw up or have diarrhea, arriving perfectly awake and much calmer. He was groggy the next day, but a good nap cured that. I would highly recommend ace promazine.
Date published: 2017-08-14
Rated 1 out of 5 by from Heavy and serious sedative My dog has very serious reaction to fireworks. I tried this years ago, thought it was good at first, as it knocked her out. (Only used 1/3 of the recommended dosage) BUT after a few uses I started to see a pattern of her being completely WASTED; Heavy breathing, stumbling, panting. Membranes covering her eyes. SO, I started doing more research online and talked with a few veterinarians who advised me not to use this. In my opinion there are far better anti anxiety prescriptions that just "take the scary away" rather than just making your dog immobile.
Date published: 2017-07-13
Rated 5 out of 5 by from Worked well Our 10 year old shitzu has a very hard time going to the groomer. We give him half a tablet an hour before and another half tablet a half hour before the appt. Seems to work well and makes it much easier on the groomer and Rocky. Also, it does not seem to have any side effects like over sedation.
Date published: 2017-02-01
Rated 5 out of 5 by from Anixety relief Our little Pekingese is afraid of any loud noise, we did not know what to for the little guy. Our vet recommended this product and it works great.
Date published: 2017-01-18
Rated 5 out of 5 by from Very effective! Got this for my 6.5 lbs chihuahua. he has car motion sickness and this medicine sure does work really well. he was a little kinds drunk but i was surprised because he was still active and playing with other dogs. he didn't threw up anymore as well!
Date published: 2016-11-09
Rated 5 out of 5 by from Dog had broke foot I have a Doberman and she gets anxiety even if she had pain pills during her recovery got this medication from my veterinarian on a follow-up because my dog would jump around like a poodle and I was concerned with her injuring herself further during this healing time this medication is great it subsided her anxiety and from her bolting out the door to go to the bathroom I would give this a high review as the first time I've ever seen my dog relax as she should after surgery
Date published: 2016-09-01
Rated 4 out of 5 by from My 11 year old Rat terrier is scared to death of lighting and thunderstorms, up till recently this drug has worked great, but the last few times, even though I have only given her 1/2 the dosage, she has been experiencing light seizure activity. Very scary! I have decided to quit giving it to her entirely.
Date published: 2016-07-17
  • y_2018, m_1, d_11, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.3
  • cp_1, bvpage1
  • co_hasreviews, tv_1, tr_73
  • loc_en_US, sid_prod10209, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_1800petmeds
Q&A

How long does a 25ng tablet last in a 55lb dog 

Asked by: Kava
Thank you for your question. The effects may last 6-8 hours.
Answered by: Adriane
Date published: 2017-12-15

My veterinarian gave this medication, half tablet, to my dog last night for symptoms of anxiety, she's a female boxer, approx 70 lb, . My dog came home and had a seizure. Why would this happen?

Asked by: NyLew
Acepromazine is classified as a phenothiazine neuroleptic, which means it modifies the chemicals in your pets brain to change their behavior. Its a tranquilizer that depresses the central nervous system. The mechanism of action is not exactly known, however, its thought to block receptors of dopamine in the brain, a chemical used for cell-to-cell communication. Acepromazine can lower the seizure threshold and be a factor in eliciting seizures in dogs who are pre-disposed.
Answered by: Lisa M
Date published: 2017-11-24

If drug expired in 2012, is it still safe to give? Got prescription for 4th of July for anxiety so only use a couple of days a year

Asked by: Maria
This medication actually does not help wit anxiety and is generally a bad idea to give to anxious animals as it can have the opposite effect. They are still anxious in their head but can't focus or move really. The drug is just a tranquilizer to make them tired/sedated/calm. If your dog has anxiety, it may make them panic because they feel have little control over themselves and will feel the need to be defensive. I am a vet tech at an animal shelter and we generally use this drug to help with overly excited animals that need to remain calm like heartworm positive dogs undergoing treatment, or injured dogs. There are far better medications for dogs with anxiety where you do not need to worry about it having an opposite effect. Alprazolam and trazodone both work well. 
Answered by: Nicki
Date published: 2017-09-18

My dog weighs 9 ponds how many milligrams do I give him?

Asked by: Carr0313
Thank you for your question. The dosing instructions for the medication states to give 0.25-1 mg/lb of pet's body weight by mouth. The exact mg dosage is determined by your veterinarian.
Answered by: Crystal PetMed Pro
Date published: 2017-09-05

My dog bites when you try to groom his face. Does this calm them down enough to keep him from biting?

Asked by: Carr0323
Yes. Acepromazine is classified as a phenothiazine neuroleptic, which means it modifies the chemicals in your pets brain to change their behavior. Its a tranquilizer that depresses the central nervous system.
Answered by: Cherley Petmeds Pro
Date published: 2017-09-03

How long does the effects of the pill last?

Asked by: Cole14
An acepromazine dose typically lasts about 6 to 8 hours.
Answered by: Lisa M
Date published: 2017-08-31

I gave my 16 lb. Yorkiepoo 2.5 mg. about q 4 hrs. and it only took the edge off her anxiety re off-roading. Can I give her 5 mg. q 4 hrs.? She was very quiet the day after; was it the med aftereffect?

Asked by: Dutchmom
Hello Dutchmom, the recommended dose for this medication is 0.25-1 mg per pound of pet's body weight. Please, give only as prescribed by a veterinarian as to avoid any side effects in your pet. This medication is very strong and its effects, including sedation, usually last 6 – 8 hours after taking it. If you're thinking about raising the dose, it's best to consult your veterinarian, as they may have an safer alternative medication that they might want your pet to try.
Answered by: Nemi Pharmacy Intern
Date published: 2017-07-22

I have a SUPER hyperactive 9 month old, 8 pound Chihuahua Mix. I cant take her to clip her nails without her nearly drawing blood from either myself or the groomer. Can i give her this medication to calm her down enough to get through the nail clipping?

Asked by: AMA20
Yes this medication is ok to give to your dog. Consult with your veterinarian on dose and a prescription.
Answered by: Ben B
Date published: 2017-02-21
  • y_2018, m_1, d_11, h_9CST
  • bvseo_bulk, prod_bvqa, vn_bulk_2.0.3
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_102
  • loc_en_US, sid_prod10209, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_1800petmeds
Get 10% OFF Now Offer
Close
Live Chat Share Website Feedback