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What is Semintra?
Semintra is the only FDA approved treatment for the control of systemic hypertension in cats. The easy-to-give liquid formula is designed to make management of feline hypertension easier for cat parents and veterinarians. It can be given directly by mouth, or next to or on top of a small amount of food. Semintra requires a prescription from your veterinarian.
Cats (9 months of age or older)
- Controls systemic hypertension in cats
- Easy to give liquid formula
- Give directly by mouth, or next to or on top of a small amount of food
How does Semintra work?
Semintra (telmisartan oral solution) is a clear, colorless to yellowish viscous solution containing 10 mg/mL telmisartan. Telmisartan is an orally active, non-peptide, selective angiotensin II subtype 1 (AT1) receptor blocker, which helps control hypertension.
Semintra has not been evaluated in cats with systolic blood pressure >200 mm Hg. Semintra can cause mild anemia or non-regenerative anemia. Cats should be monitored for anemia when initiating treatment with Semintra. Semintra may cause inappetence (loss of appetite) and weight loss in some cats. Cats should be monitored for weight loss when initiating treatment with Semintra. Use with caution in cats with a history of vomiting, inappetence or weight loss. The safe use of Semintra in cats with hepatic disease has not been evaluated. Semintra is metabolized by the liver. The safe use of Semintra has not been evaluated in cats less than 9 months of age. The safe use of Semintra has not been evaluated in cats that are pregnant, lactating, or intended for breeding. The safe use with other anti-hypertensive medications has not been evaluated.
Seminta (Boehringer Ingelheim)
Telmisartan oral solution
What is the most important thing I should know about Semintra?
Semintra is indicated for the control of systemic hypertension in cats. It requires a prescription from your veterinarian. It can be given by the mouth or over a small amount of food. Semintra comes with an oral dosing syringe. Semintra can cause mild anemia or non-regenerative anemia. Cats should be monitored for anemia when initiating treatment with Semintra.
What should I discuss with my veterinarian before giving Semintra to my pet?
Let your veterinarian know if your cat is prone to vomiting, inappetence, or weight loss, or if they have hepatic disease, or if they are pregnant, nursing, or may be used for breeding.
How should Semintra be given?
Semintra should be administered using the dosing syringe provided in the package. Semintra can be administered directly into the mouth, or next to or on top of a small amount of food. Do not mix into food. The initial dose is 0.68 mg/lb dose twice daily for 14 days, followed by 0.91 mg/lb once daily to maintain control. The dose may be reduced by 0.23 mg/lb increments to a minimum of 0.23 mg/lb to optimize dosing and prevent hypotensive state.
What are the potential side effects of Semintra?
The most common side effects reported in field studies include: vomiting, diarrhea, lethargy, anemia, dehydration, poor appetite, and weight loss.
What happens if I miss giving a dose of Semintra?
Give the missed dose as soon as you remember. If it is too close to the next dose, skip the missed dose and resume a regular dosing schedule.
What happens if I overdose my pet on Semintra?
If an overdose is suspected, contact your veterinarian immediately.
What other drugs will affect Semintra?
The safe use with other anti-hypertensive medications has not been evaluated. Talk to your veterinarian
- Semintra should be administered using the dosing syringe provided in the package. The dosing syringe fits onto the bottle and has 0.1 mL incremental marks. The dose should be rounded to the nearest 0.1 mL.
- Semintra can be administered directly into the mouth, or next to or on top of a small amount of food. Do not mix into food.
- After administration close the bottle tightly with the cap. Rinse the dosing syringe with water and let air dry.
If your cat vomits within 30 minutes of dosing, your cat may be re-dosed.
The initial dose of Semintra is 1.5 mg/kg (0.68 mg/lb) orally twice daily for 14 days, followed by 2 mg/kg (0.91 mg/lb) orally once daily. The dose may be reduced by 0.5 mg/kg (0.23 mg/lb) increments to a minimum of 0.5 mg/kg (0.23 mg/lb) orally once daily to manage Semintra-induced hypotension.
|Dogs||Do not use!|
|Horses||Do not use!|
Keep out of reach of children and pets. Store at or below 77°F with excursions permitted up to 104°F. Once the bottle is opened, use the contents within six months.
|Active Ingredient (per ml)||Amount|
|Telmisartan oral solution||10 mg/ml|