AYRADIA (metronidazole) Oral Suspension

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AYRADIA (metronidazole) Oral Suspension
- 125 mg/ml - 30 ml
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What is AYRADIA (metronidazole) Oral Suspension?

AYRADIA (metronidazole oral suspension) for dogs is an antibiotic, it is the first FDA-approved flavored oral metronidazole solution for dogs and puppies. AYRADIA oral suspension is for the treatment of Giardia duodenalis infection in dogs.

Suitable for:

Dogs

Benefits:

  • AYRADIA oral suspension is indicated for the treatment of Giardia duodenalis infection in dogs
  • AYRADIA oral suspension is the first FDA-approved flavored oral metronidazole solution for dogs and puppies
  • The active ingredient is metronidazole, with both antibacterial and antiprotozoal activities
  • Metronidazole is well established as effective and safe when given as prescribed
  • The flavored liquid formulation makes accurate dosing easy for dogs and puppies
  • AYRADIA oral suspension can be given with a small amount of food or directly into your dog’s mouth

How does AYRADIA (metronidazole) Oral Suspension work?

The active ingredient is metronidazole, with both antibacterial and antiprotozoal activities. Metronidazole is well-established as effective and safe when given as prescribed. The flavored liquid formulation makes accurate dosing easy for dogs and puppies. AYRADIA oral suspension can be given with a small amount of food or directly into your dog’s mouth.

Caution:

Keep out of reach of children. Not for use in humans. Metronidazole has been found to cause cancer in laboratory animals; however, there is inadequate evidence of carcinogenicity in humans. People with known sensitivity to metronidazole or other nitroimidazole derivatives should avoid contact with AYRADIA oral suspension. This product is not a skin or eye irritant but is a skin sensitizer which can potentially cause allergic contact dermatitis. Wash hands after use. Avoid contact with skin. In case of skin contact, wash the affected area thoroughly. Persons who come in contact with the dog’s saliva during the first five minutes after administration should wash their hands. If the drug has been applied to dog food, the dog food should be kept away from children until after the dog has finished eating. Avoid accidental ingestion. In case of accidental ingestion, seek medical advice immediately.

How should I store this product?

Keep AYRADIA oral suspension in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Store below 86°F (30°C) in the upright position. Once opened, use within 6 months.

What is the most important information I should know about AYRADIA (metronidazole) Oral Suspension?

Your veterinarian has prescribed this medication because AYRADIA oral suspension is indicated for the treatment of Giardia duodenalis infection in dogs. Giardia is a protozoan parasite that is transmitted from the feces of another animal infected with the parasite. It can be commonly found in soil, food, and water contaminated with parasite-infected feces, and then ingested. Do not give this to any other animal that does not have a prescription.

What should I discuss with my veterinarian before giving AYRADIA (metronidazole) Oral Suspension to my pet?

Always talk with your veterinarian if you have any questions about your dog’s condition or medications. Tell your veterinarian if your pet is allergic to any medications. Do not give this medication if your pet is allergic to nitroimidazole compounds, including metronidazole. Tell your veterinarian if your pet has a history of liver problems. Tell your veterinarian if your pet is pregnant or lactating or if you plan to breed your pet.

How should AYRADIA (metronidazole) Oral Suspension be given/administered?

Give AYRADIA to your pet exactly as prescribed by your veterinarian, including the dosage, timing, and duration of treatment. Ensure your dog completes the entire course of treatment unless advised otherwise by your veterinarian — even if your dog seems to be feeling better.

What are the potential side effects of AYRADIA (metronidazole) Oral Suspension?

The most common side effects seen were diarrhea or vomiting. Other side effects seen included hyperactivity, excessive salivation, abdominal pain, excessive thirst, excessive urination, not eating, ear infection, and lethargy. Contact your veterinarian if you observe any signs of illness.

What happens if I overdose my pet on AYRADIA (metronidazole) Oral Suspension?

Contact your veterinarian immediately.

What special precautions are there?

Use with caution in dogs with liver dysfunction. Neurologic effects have been associated with AYRADIA oral suspension use at high doses, but individual variation in sensitivity of dogs to the neurologic effects of metronidazole has been reported. The safe use of this drug in dogs intended for breeding purposes and in pregnant or lactating dogs has not been evaluated.

AYRADIA (metronidazole) Oral Suspension Directions:

  • Using the supplied syringe, administer the dose prescribed by your veterinarian twice daily for five consecutive days.
  • Shake the bottle vigorously before use
  • Unscrew and remove the protective overcap.
  • Firmly push the valve on the bottle with the tip of the syringe.
  • Insert the syringe into the upper white part of the delivery system (finger-grip) by pushing firmly, then, while pushing, turn the syringe to the right (clockwise) until the green smile appears.
  • Turn the bottle upside down and fill the syringe with the prescribed volume of the product by pulling the plunger, in the upside-down position, until it reaches the graduation corresponding to the correct mL dose as indicated at the top of the syringe ring. Each line on the included dosing syringe represents 0.1 mL of oral suspension.
  • Once the correct volume of the product has been drawn into the syringe, turn the bottle right side up. Unscrew the syringe from the delivery system without pushing by turning it to the left (counterclockwise) until the red smile appears again, then continue to turn in order to unfasten the syringe. The system can also be closed by turning the finger-grip manually.
  • Screw the protective overcap back on. Administer the product orally or in a small amount of food.
  • For dogs over 15 kg (33 lb), using the included 3 mL syringe, repeat steps as needed to administer the total dose.
Tip:

For dogs weighing more than 15 kg (33 lb), the total dose volume will be divided over multiple syringe draws because the dosing syringe only holds up to 3 mL. Alternatively, a standard luer lock syringe that holds more than 3 mL can also be used.

AYRADIA (metronidazole) Oral Suspension Dosage:

Dosage for Dogs
WeightDosage
All WeightsAYRADIA oral suspension is administered orally at a dose of 25 mg/kg (11.3 mg/lb) of body weight, using the supplied syringe, twice daily for five consecutive days.
Dosage for Cats
Cats
Do not use!
Dosage for Horses
Horses
Do not use!

AYRADIA (metronidazole) Oral Suspension Ingredients:

Active Ingredient
metronidazole

What is AYRADIA (metronidazole) Oral Suspension?

AYRADIA (metronidazole oral suspension) for dogs is an antibiotic, it is the first FDA-approved flavored oral metronidazole solution for dogs and puppies. AYRADIA oral suspension is for the treatment of Giardia duodenalis infection in dogs.

Suitable for:

Dogs

Benefits:

  • AYRADIA oral suspension is indicated for the treatment of Giardia duodenalis infection in dogs
  • AYRADIA oral suspension is the first FDA-approved flavored oral metronidazole solution for dogs and puppies
  • The active ingredient is metronidazole, with both antibacterial and antiprotozoal activities
  • Metronidazole is well established as effective and safe when given as prescribed
  • The flavored liquid formulation makes accurate dosing easy for dogs and puppies
  • AYRADIA oral suspension can be given with a small amount of food or directly into your dog’s mouth

How does AYRADIA (metronidazole) Oral Suspension work?

The active ingredient is metronidazole, with both antibacterial and antiprotozoal activities. Metronidazole is well-established as effective and safe when given as prescribed. The flavored liquid formulation makes accurate dosing easy for dogs and puppies. AYRADIA oral suspension can be given with a small amount of food or directly into your dog’s mouth.

Caution:

Keep out of reach of children. Not for use in humans. Metronidazole has been found to cause cancer in laboratory animals; however, there is inadequate evidence of carcinogenicity in humans. People with known sensitivity to metronidazole or other nitroimidazole derivatives should avoid contact with AYRADIA oral suspension. This product is not a skin or eye irritant but is a skin sensitizer which can potentially cause allergic contact dermatitis. Wash hands after use. Avoid contact with skin. In case of skin contact, wash the affected area thoroughly. Persons who come in contact with the dog’s saliva during the first five minutes after administration should wash their hands. If the drug has been applied to dog food, the dog food should be kept away from children until after the dog has finished eating. Avoid accidental ingestion. In case of accidental ingestion, seek medical advice immediately.

How should I store this product?

Keep AYRADIA oral suspension in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Store below 86°F (30°C) in the upright position. Once opened, use within 6 months.

What is the most important information I should know about AYRADIA (metronidazole) Oral Suspension?

Your veterinarian has prescribed this medication because AYRADIA oral suspension is indicated for the treatment of Giardia duodenalis infection in dogs. Giardia is a protozoan parasite that is transmitted from the feces of another animal infected with the parasite. It can be commonly found in soil, food, and water contaminated with parasite-infected feces, and then ingested. Do not give this to any other animal that does not have a prescription.

What should I discuss with my veterinarian before giving AYRADIA (metronidazole) Oral Suspension to my pet?

Always talk with your veterinarian if you have any questions about your dog’s condition or medications. Tell your veterinarian if your pet is allergic to any medications. Do not give this medication if your pet is allergic to nitroimidazole compounds, including metronidazole. Tell your veterinarian if your pet has a history of liver problems. Tell your veterinarian if your pet is pregnant or lactating or if you plan to breed your pet.

How should AYRADIA (metronidazole) Oral Suspension be given/administered?

Give AYRADIA to your pet exactly as prescribed by your veterinarian, including the dosage, timing, and duration of treatment. Ensure your dog completes the entire course of treatment unless advised otherwise by your veterinarian — even if your dog seems to be feeling better.

What are the potential side effects of AYRADIA (metronidazole) Oral Suspension?

The most common side effects seen were diarrhea or vomiting. Other side effects seen included hyperactivity, excessive salivation, abdominal pain, excessive thirst, excessive urination, not eating, ear infection, and lethargy. Contact your veterinarian if you observe any signs of illness.

What happens if I overdose my pet on AYRADIA (metronidazole) Oral Suspension?

Contact your veterinarian immediately.

What special precautions are there?

Use with caution in dogs with liver dysfunction. Neurologic effects have been associated with AYRADIA oral suspension use at high doses, but individual variation in sensitivity of dogs to the neurologic effects of metronidazole has been reported. The safe use of this drug in dogs intended for breeding purposes and in pregnant or lactating dogs has not been evaluated.

AYRADIA (metronidazole) Oral Suspension Directions:

  • Using the supplied syringe, administer the dose prescribed by your veterinarian twice daily for five consecutive days.
  • Shake the bottle vigorously before use
  • Unscrew and remove the protective overcap.
  • Firmly push the valve on the bottle with the tip of the syringe.
  • Insert the syringe into the upper white part of the delivery system (finger-grip) by pushing firmly, then, while pushing, turn the syringe to the right (clockwise) until the green smile appears.
  • Turn the bottle upside down and fill the syringe with the prescribed volume of the product by pulling the plunger, in the upside-down position, until it reaches the graduation corresponding to the correct mL dose as indicated at the top of the syringe ring. Each line on the included dosing syringe represents 0.1 mL of oral suspension.
  • Once the correct volume of the product has been drawn into the syringe, turn the bottle right side up. Unscrew the syringe from the delivery system without pushing by turning it to the left (counterclockwise) until the red smile appears again, then continue to turn in order to unfasten the syringe. The system can also be closed by turning the finger-grip manually.
  • Screw the protective overcap back on. Administer the product orally or in a small amount of food.
  • For dogs over 15 kg (33 lb), using the included 3 mL syringe, repeat steps as needed to administer the total dose.
Tip:

For dogs weighing more than 15 kg (33 lb), the total dose volume will be divided over multiple syringe draws because the dosing syringe only holds up to 3 mL. Alternatively, a standard luer lock syringe that holds more than 3 mL can also be used.

AYRADIA (metronidazole) Oral Suspension Dosage:

Dosage for Dogs
WeightDosage
All WeightsAYRADIA oral suspension is administered orally at a dose of 25 mg/kg (11.3 mg/lb) of body weight, using the supplied syringe, twice daily for five consecutive days.
Dosage for Cats
Cats
Do not use!
Dosage for Horses
Horses
Do not use!

AYRADIA (metronidazole) Oral Suspension Ingredients:

Active Ingredient
metronidazole

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