Trifexis

5 out of 5 Customer Rating
Trifexis is rated 4.1 out of 5 by 895.
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Starts $155.70 $108.99
Most orders ship the same day

Trifexis

5 out of 5 Customer Rating
Trifexis is rated 4.1 out of 5 by 895.
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Starts $155.70 $108.99
Most orders ship the same day
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Reviews

Rated 2 out of 5 by from Difficult to use due to taste I had to switch back to Heartgard after my vet gave me this for my dog. It smells like mold coming out of the blister and must taste worse, because my dog wouldn’t touch any food I tried to hide it in. I managed to trick him a couple times by feeding him bites of meat before the pill, so he got to gulping, but even that only worked occasionally. It did seem to work for fleas when he did take it, but Heartgard plus something like Frontline is far, far easier to use and the cost is similar. Not worth the trouble.
Date published: 2020-06-14
Rated 4 out of 5 by from Effective Product Very effective, kills fleas quickly. I see my dogs scratch but never see a flea. Assuming the fleas die off as soon as they bite. Only con is the size of the pill and the difficulty to get my dogs to eat it. They don;t like it so I have to break up the pill and force it down. Not fun!
Date published: 2020-06-09
Rated 5 out of 5 by from Charley like his milk bone. I though nice tough.what I really like is the price !! GREAT!!
Date published: 2020-06-09
Rated 5 out of 5 by from Happy with Trifectis I have had all of my dogs on Trifexis for the last 9 years. I have never seen any fleas and none of their test have ever came back positive for any of covered worms. Out of my 3 all of them will eat the pill like a treat so I assume the taste is acceptable. I just wish they covered ticks as well!
Date published: 2020-06-08
Rated 4 out of 5 by from Works great...tastes awful! My only reason for 4 stars is that this medication smells and tastes REALLY bad. I have to put it in my dog's throat...there is no way he will eat it, no matter what it's wrapped in. But it's a monthly ritual that he abides...with plenty of snuggles afterwards. That said, it works well. When I rescued him, he had fleas, worms and more. Since starting Trifexis, years ago, he has never had a problem. I purchase from 1800PetMeds because it's the least expensive price I've found, they work directly with my Vet, and delivery is dependable. The treat they always send is a nice little bonus.
Date published: 2020-06-02
Rated 5 out of 5 by from Heartworms/trifexis Love this product...no fleas on cats or my three dogs...Sadie was a rescue ...she tested positive for heart worms..we kept up with the monthly Trifexis..her last checkup she was heart worm FREE... Thank you Trifexis....
Date published: 2020-06-01
Rated 1 out of 5 by from Pill had no flavor ..,have to trick/force to take The pills (near the size of a hockey puck) must have no odor or taste dogs like... my Golden will eat anything! won’t touch pill ... why a height ticket item like this can’t be made to taste ok is beyond me! I’ll be switching back to prior meds.
Date published: 2020-06-01
Rated 5 out of 5 by from Trifexis I have been purchasing this product since I have had my boxer. It will be five years ago in July that he has been using it. It has worked great on him. I am very pleased with this product. I love working with 1800PetMeds while ordering this product. I get great service. I definitely recommend this product.
Date published: 2020-05-31
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Questions

my puppy is not quite 11 weeks old and is growing fast .  I assume purchasing  her size range wont be practical in 2 months .  So can I double up  after she grows well beyond twenty pounds ? It would be a waste of four tablets otherwise .

Asked by: Buttons
For growing puppies, I recommend buying Trifexis one month at a time to ensure the correct dosage. I believe PetMeds will sell 1 tablet at a time, but please call them at 1-800-738-6337 to confirm. Othgerwise, you should be able to get Trifexis from your veterinarian one month at a time.
Answered by: SuzyCVT
Date published: 2020-08-25

Is a prescription required in order to order Trifexis for my 50 lb dog?

Asked by: Callie
Thank you for your question. Yes, Trifexis is a prescription medication. Once you place an order our Pharmacy would contact your veterinarian directly for the prescription authorization.
Answered by: Crystal RPTechnician
Date published: 2020-08-10

My fur baby takes a tablet, it is not chewable...I did not see it in pill form...

Asked by: Sookie
Thank you for your question. Trifexis is made as a tasty, beef-flavored chewable tablet.
Answered by: Crystal RPTechnician
Date published: 2020-07-10

Can your pet take trefexis and something for ticks will this cause a reaction

Asked by: Jade
Since most tick medications also treat for fleas, using Trifexis would "double-dose" your pet on flea control. I recommend that you use 2 separate products, one for fleas and ticks, such as NexGard, Bravecto or Simparica, and another product for heartworm prevention, such as Interceptor (with or without the "Plus"), Milbeguard or HeartGard Plus.
Answered by: SuzyCVT
Date published: 2020-07-04

Is the extra 20 percent taken off at checkout 

Asked by: Di71
Thank you for your question. When at checkout you must apply the offer code manually. The box to enter your offer code is below your subtotal on the left when viewing your cart before you click checkout. Enter your offer code in the box then hit " apply" and then proceed with checkout.
Answered by: Crystal RPTechnician
Date published: 2020-06-19

Does this cover ticks as well?

Asked by: Nala and Simba
No. Trifexis only prevents heartworms, controls hookworm, roundworms and whipworms, and kill fleas.
Answered by: SuzyCVT
Date published: 2020-06-08

What is the side effects

Asked by: Cathy
Per the product info provided on this website: "Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Trifexis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, itching, hyperactivity. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to your pet. The use of ivermectin at higher than FDA-approved doses at the same time as Trifexis can result in serious side effects."
Answered by: SuzyCVT
Date published: 2020-06-02

Do I have to have a prescription for this

Asked by: Karen 59
Yes, all heartworm preventions require a veterinarian's prescription.
Answered by: SuzyCVT
Date published: 2020-05-22
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What is Trifexis® (spinosad + milbemycin oxime)?

Trifexis is a chewable tablet that kills fleas and prevents infestations, protects against heartworms, and treats and controls adult hookworm, roundworm, and whipworm infections. This tasty, beef-flavored tablet is easy to give your dog to protect against multiple parasites with one medication. Trifexis chewable tablets are for monthly use in dogs and puppies 8 weeks of age and older and 5 lbs of body weight or more. Trifexis requires a prescription from your veterinarian.

For:

Dogs (8+ weeks of age, weighing 5+ lbs)

Benefits:

  • Provides 3-in-1 parasite protection against heartworm, fleas, and intestinal parasites.
  • Begins killing biting fleas within 30 minutes
  • Kills fleas before they can lay eggs
  • Prevents heartworm disease
  • Treats and controls roundworms, hookworms, and whipworms
  • Artificial beef-flavored tablet
  • Easy-to-administer chewable tablet

How does Trifexis work?

Spinosad, an active ingredient in Trifexis, starts to work within 30 minutes to kill fleas and has been proven to kill 100% of all biting fleas within 4 hours. Trifexis prevents heartworm disease by killing microfilariae and larvae from maturing into adult heartworms.

Cautions:

Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis chewable tablets. Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. Puppies less than 14 weeks of age may experience a higher rate of vomiting. Consult your veterinarian for pregnant or lactating dogs.

Brand Name:

Trifexis (Elanco Animal Health)

Generic Name:

Spinosad and Milbemycin oxime

What is the most important thing I should know about Trifexis?

Trifexis is a prescription medication FDA approved for use in dogs 8 weeks of age or older and 5 lbs of body weight or more. Trifexis contains spinosad and milbemycin oxime and is indicated for the prevention of heartworm disease. Trifexis kills fleas and is indicated for the prevention and treatment of flea infestations, and the treatment and control of adult hookworm, adult roundworm, and adult whipworm infections. Trifexis is available in a Pink box for dogs 5 to 10 lbs (140 mg/2.3 mg), Orange box for dogs 10.1 to 20 lbs (270 mg/4.5 mg), Green box for dogs 20.1 to 40 lbs (560 mg/9.3 mg), Blue box for dogs 40.1 to 60 lbs (810 mg/13.5 mg), and Brown box for dogs 60.1 to 120 lbs (1620 mg/27 mg). For dogs over 120 lbs, give the appropriate combination of tablets. See Trifexis label for complete safety information.

What should I discuss with my veterinarian before giving Trifexis to my pet?

Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog has a history of seizures (epilepsy).

How should Trifexis be given?

Give Trifexis chewable tablets once a month with food. Trifexis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose your pet with another full dose. Consult your veterinarian for pregnant or lactating dogs.

What are the potential side effects of Trifexis?

Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Trifexis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, itching, hyperactivity. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to your pet. The use of ivermectin at higher than FDA-approved doses at the same time as Trifexis can result in serious side effects.

What happens if I miss giving a dose of Trifexis?

Give the missed dose with food as soon as you remember and resume a monthly dosing schedule.

What happens if I overdose my pet on Trifexis?

Overdose of this medication is unlikely. However, if an overdose is suspected, contact your veterinarian or veterinary emergency room. Symptoms of overdose that may occur include vomiting.

What should I avoid while giving Trifexis to my pet?

Your pet may maintain normal activities and interactions while being given Trifexis. The safe use of Trifexis chewable tablets in male dogs intended for breeding has not been established.

What other drugs will affect Trifexis?

Talk to your veterinarian before giving any prescription or over the counter medications.

Trifexis Directions:

  • Please view the chart below for the correct dosage of Trifexis for your dog.
Tip:

Always provide fresh drinking water.

Trifexis Dosage for Dogs (8+ weeks of age, weighing 5+ lbs)

Dogs (8+ weeks of age, weighing 5+ lbs)
WeightDosage
5-10 lbsGive one tablet (Pink box)
10.1-20 lbsGive one tablet (Orange box)
20.1-40 lbsGive one tablet (Green box)
40.1-60 lbsGive one tablet (Blue box)
60.1-120 lbsGive one tablet (Brown box)
Over 120 lbsAdminister the appropriate combination of tablets
Trifexis Dosage for Cats:
Cats
Do not use!
Trifexis Dosage for Horses:
Horses
Do not use!
Storage:

Store Trifexis at room temperature (68°-77° F). Keep out of the reach of children.

Trifexis Ingredients:

Trifexis Pink box (5-10 lbs):
Active Ingredients per tabletAmount
Spinosad140 mg
Milbemycin oxime2.3 mg
Trifexis Orange box (10.1-20 lbs):
Active Ingredients per tabletAmount
Spinosad270 mg
Milbemycin oxime4.5 mg
Trifexis Green box (20.1-40 lbs):
Active Ingredients per tabletAmount
Spinosad560 mg
Milbemycin oxime9.3 mg
Trifexis Blue box(40.1-60 lbs):
Active Ingredients per tabletAmount
Spinosad810 mg
Milbemycin oxime13.5 mg
Trifexis Brown box(60.1-120 lbs):
Active Ingredients per tabletAmount
Spinosad1620 mg
Milbemycin oxime27 mg

What is Trifexis® (spinosad + milbemycin oxime)?

Trifexis is a chewable tablet that kills fleas and prevents infestations, protects against heartworms, and treats and controls adult hookworm, roundworm, and whipworm infections. This tasty, beef-flavored tablet is easy to give your dog to protect against multiple parasites with one medication. Trifexis chewable tablets are for monthly use in dogs and puppies 8 weeks of age and older and 5 lbs of body weight or more. Trifexis requires a prescription from your veterinarian.

For:

Dogs (8+ weeks of age, weighing 5+ lbs)

Benefits:

  • Provides 3-in-1 parasite protection against heartworm, fleas, and intestinal parasites.
  • Begins killing biting fleas within 30 minutes
  • Kills fleas before they can lay eggs
  • Prevents heartworm disease
  • Treats and controls roundworms, hookworms, and whipworms
  • Artificial beef-flavored tablet
  • Easy-to-administer chewable tablet

How does Trifexis work?

Spinosad, an active ingredient in Trifexis, starts to work within 30 minutes to kill fleas and has been proven to kill 100% of all biting fleas within 4 hours. Trifexis prevents heartworm disease by killing microfilariae and larvae from maturing into adult heartworms.

Cautions:

Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis chewable tablets. Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. Puppies less than 14 weeks of age may experience a higher rate of vomiting. Consult your veterinarian for pregnant or lactating dogs.

Brand Name:

Trifexis (Elanco Animal Health)

Generic Name:

Spinosad and Milbemycin oxime

What is the most important thing I should know about Trifexis?

Trifexis is a prescription medication FDA approved for use in dogs 8 weeks of age or older and 5 lbs of body weight or more. Trifexis contains spinosad and milbemycin oxime and is indicated for the prevention of heartworm disease. Trifexis kills fleas and is indicated for the prevention and treatment of flea infestations, and the treatment and control of adult hookworm, adult roundworm, and adult whipworm infections. Trifexis is available in a Pink box for dogs 5 to 10 lbs (140 mg/2.3 mg), Orange box for dogs 10.1 to 20 lbs (270 mg/4.5 mg), Green box for dogs 20.1 to 40 lbs (560 mg/9.3 mg), Blue box for dogs 40.1 to 60 lbs (810 mg/13.5 mg), and Brown box for dogs 60.1 to 120 lbs (1620 mg/27 mg). For dogs over 120 lbs, give the appropriate combination of tablets. See Trifexis label for complete safety information.

What should I discuss with my veterinarian before giving Trifexis to my pet?

Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog has a history of seizures (epilepsy).

How should Trifexis be given?

Give Trifexis chewable tablets once a month with food. Trifexis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose your pet with another full dose. Consult your veterinarian for pregnant or lactating dogs.

What are the potential side effects of Trifexis?

Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Trifexis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, itching, hyperactivity. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to your pet. The use of ivermectin at higher than FDA-approved doses at the same time as Trifexis can result in serious side effects.

What happens if I miss giving a dose of Trifexis?

Give the missed dose with food as soon as you remember and resume a monthly dosing schedule.

What happens if I overdose my pet on Trifexis?

Overdose of this medication is unlikely. However, if an overdose is suspected, contact your veterinarian or veterinary emergency room. Symptoms of overdose that may occur include vomiting.

What should I avoid while giving Trifexis to my pet?

Your pet may maintain normal activities and interactions while being given Trifexis. The safe use of Trifexis chewable tablets in male dogs intended for breeding has not been established.

What other drugs will affect Trifexis?

Talk to your veterinarian before giving any prescription or over the counter medications.

Trifexis Directions:

  • Please view the chart below for the correct dosage of Trifexis for your dog.
Tip:

Always provide fresh drinking water.

Trifexis Dosage for Dogs (8+ weeks of age, weighing 5+ lbs)

Dogs (8+ weeks of age, weighing 5+ lbs)
WeightDosage
5-10 lbsGive one tablet (Pink box)
10.1-20 lbsGive one tablet (Orange box)
20.1-40 lbsGive one tablet (Green box)
40.1-60 lbsGive one tablet (Blue box)
60.1-120 lbsGive one tablet (Brown box)
Over 120 lbsAdminister the appropriate combination of tablets
Trifexis Dosage for Cats:
Cats
Do not use!
Trifexis Dosage for Horses:
Horses
Do not use!
Storage:

Store Trifexis at room temperature (68°-77° F). Keep out of the reach of children.

Trifexis Ingredients:

Trifexis Pink box (5-10 lbs):
Active Ingredients per tabletAmount
Spinosad140 mg
Milbemycin oxime2.3 mg
Trifexis Orange box (10.1-20 lbs):
Active Ingredients per tabletAmount
Spinosad270 mg
Milbemycin oxime4.5 mg
Trifexis Green box (20.1-40 lbs):
Active Ingredients per tabletAmount
Spinosad560 mg
Milbemycin oxime9.3 mg
Trifexis Blue box(40.1-60 lbs):
Active Ingredients per tabletAmount
Spinosad810 mg
Milbemycin oxime13.5 mg
Trifexis Brown box(60.1-120 lbs):
Active Ingredients per tabletAmount
Spinosad1620 mg
Milbemycin oxime27 mg