4.8 out of 5 Customer Rating
Simplicef is rated 4.5 out of 5 by 35.
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prod10739 product detail number 1.0
Simplicef
Simplicef
SOLD PER TABLET

Simplicef

4.8 out of 5 Customer Rating
Simplicef is rated 4.5 out of 5 by 35.
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Reviews

Rated 5 out of 5 by from Has worked for inconclusive diagnosis of rhinitis Our 14 year old dog was diagnosed with chronic rhinitis. I say inconclusive as we were unable to do a rhinoscooy due to her age so there are others things we can’t rule out. We’ve been treating her with Simplicef on a pulse basis, one week in and two weeks off and it has kept the severe bouts at bay for that time. Before our dog suffered pretty severely.
Date published: 2018-12-31
Rated 4 out of 5 by from Caring. Maggie doesn't like the taste. I have to crush in food.It's bitter but her wound is healing nicely.
Date published: 2018-12-08
Rated 5 out of 5 by from Simplicef is a Great Antibiotic I used this with my little Shih Tzu for her skin. She would get so itchy red and irritated. Simplicef is the only medicine that helped her. We could see a difference after just one pill. I recommended to a friend for her Maltipoo and it worked for her as well. A miracle! Thanks
Date published: 2018-04-28
Rated 5 out of 5 by from simplicef is a great medication I’ve got a four year old Pure Bred Shepherd that since day one He ( MAX ) has had allergies that we up until this last few weeks we haven’t found a cure for or not so much a cure but this Med is only one to make him stop itching and ripping his fur out. So if your pet is in anguish do to allergies give this medicine (SIMPLICEF) a try. Of course not all dogs are cured by same medications so do yourself a favor and only buy a weeks worth to see if it’s going to help .god Speed for your pets quick cure for no one wishes to watch their pets in misery and agony from tearing their fur out.Have a positive reaction.
Date published: 2018-03-24
Rated 1 out of 5 by from Simplicef Adverse Side Effects My Pomeranian was given Simplicef for 14 Days. Tonight he has been screaming out and whimpering in pain really stiff. Difficulty transitioning from laying position, holding front legs and hind legs like cramping, craning his neck, comforting and consoling him rubbing near neck area. I questioned why he was given a different antibiotic for his chronic condition. I am very upset. At this moment he is having another episode of pain 3rd time in the past 3 hours 30 minutes!! I think this medicine shouldn't be given to certain dogs due to adverse side effects. He is having pain and suffering uncertainty of how long this is going to last!! Now this will become another Vetrinarian visit for him with high cost. I usually take my pets to Emergency Animal Clinic After Hours but, since just recently took both dogs to Vet given pharmaceuticals.
Date published: 2017-05-18
Rated 5 out of 5 by from Ordered meds one day 3 days later they were at my door. Very quick reasonably priced and great service . Very happy with company.
Date published: 2017-01-21
Rated 3 out of 5 by from bad product My pet was prescribed this on Tuesday Gave him a half pill for 2 days. He became very lathargic,feverish and now has some kind of muscle or joint pain. Whines when he moves. Stopped giving him the pill, hopefully he'll get back to his old self. Will never use again.
Date published: 2016-10-08
Rated 5 out of 5 by from Great service My dog gets allergies in the summer months and this product really helps his skin. I love dealing with petmeds they are great
Date published: 2015-12-14
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Questions

Do I need a perscription for Simpicef

Asked by: janie
Thank you for your question. Simplicef does require a prescription. Once an order is placed our Pharmacy would contact your veterinarian for the prescription authorization.
Answered by: Crystal RPTechnician
Date published: 2020-08-13

Can you tell me what a 200 mg SimpliCef pill looks like

Asked by: Gracie
Simplicef 200mg is an orange, oblong tablet that is scored down the middle.
Answered by: Lisa M
Date published: 2019-12-12

Can it be used as a preventative for getting a tooth pulled?

Asked by: Dobiemom
No, this product cannot be used a preventative for getting a tooth pulled.
Answered by: Crystal RPTechnician
Date published: 2019-05-12

Can this be used to treat kennel cough

Asked by: maria
Simplicef is a once-a-day antibiotic used to treat skin infections (wounds and abscesses) caused by susceptible strains of bacteria. Simplicef is an antibiotic belonging to a class of drugs called cephalosporins that fight bacteria in the body. Simplicef can be used to treat many different types of infections such as bronchitis or pneumonia as well as ear, skin, and urinary tract infections. It may also be used for purposes other than those listed. Please consult with your veterinarian so he/she can prescribe the appropriate medication for your furry baby.
Answered by: Cherley Petmeds Pro
Date published: 2019-05-31

My vet gave this for our dog he wieghs 75lbs its 200mg tablet he's on his second day he was fine on 1st pill 2nd was given today at 130pm he's acting like he can't get comfortable trying to stretch his body stomach ect he has been acting this way

Asked by: shannon
Your dog could be having an atypical reaction to Simplicef. Consult your veterinarian if his behavior continues or worsens.
Answered by: Lisa M
Date published: 2018-01-27

Does this medicine have an  expiration date ?

Asked by: Shar
Yes, the expiration dates for the product we currently have in stock are 4/2019 for Simplicef 100 mg tablets and 7/2019 for the 200 mg tablets.
Answered by: Lisa M
Date published: 2018-08-15

Can I give this to my cat ? 

Asked by: Debbie
Thank you for your question. This medication is by prescription only and is for use in dogs unless otherwise specified by a veterinarian.
Answered by: Crystal RPTechnician
Date published: 2019-03-01

Your website on 2 of my browsers after, clearing cookies, cache etc.still isn't showing Customer Reviews 9 to 31. The arrow is greyed out not allowing to read the remaining customer reviews. My Second Request to fix the issue in order to show the Vet

Asked by: beautybodacious
Thank you for your question. The product only has 31 reviews total, the reviews are only two pages long. The first page is 1-8 reviews second page is 8-31 reviews individually.
Answered by: Crystal RPTechnician
Date published: 2017-05-26
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What is Simplicef?

Simplicef is a once-a-day antibiotic used to treat skin infections (wounds and abscesses) caused by susceptible strains of bacteria. Simplicef is an antibiotic belonging to a class of drugs called cephalosporins that fight bacteria in the body. Simplicef can be used to treat many different types of infections such as bronchitis or pneumonia as well as ear, skin, and urinary tract infections. It may also be used for purposes other than those listed. Simplicef requires a prescription from your veterinarian, and is sold per tablet.

For:

Dogs

Benefits:

  • FDA-approved for treating canine bacterial skin infections
  • Simple once-a-day dosing
  • Can be given with or without food
  • Comes in a film-coated tablet for easy administration

How does Simplicef work?

Simplicef is effective against most gram-positive and gram-negative bacteria. Cephalosporin antibiotics suppress the growth of micro-organisms such as bacteria, fungi, or protozoa.

Cautions:

Contact your veterinarian in the event of an allergic reaction (such as shortness of breath, hives, swelling, rash, fainting, vomiting, diarrhea, mucus or blood in the stool, unusual bleeding, or bruising). Do not give Simplicef at the same time as antacids such as Maalox or other stomach acid-reducers, like Tagamet.

Brand Name:

Simplicef (Zoetis), Vantin (Pharmacia and Upjohn)

Generic Name:

Cefpodoxime proxetil

What is the most important thing I should know about Simplicef?

Simplicef is a prescription medication FDA-approved for use in dogs. Simplicef is available as 100 mg elliptical scored tablets and 200 mg tablets that can either be elliptical, unscored tablets marked 5229 or capsule-shaped, scored tablets marked 5229. The usual dose of Simplicef in dogs is 2.3-4.5 mg/lb, given by mouth, once a day for 5 to 7 days or 2 to 3 days beyond the cessation of clinical signs, up to a maximum of 28 days. Simplicef should be given with food to increase absorption by the body. Give all of the Simplicef that is prescribed for your pet. Symptoms may begin to improve before the infection is completely treated.

What should I discuss with my veterinarian before giving Simplicef to my pet?

Tell your veterinarian if your pet has ever had an allergic reaction to another penicillin or to a cephalosporin. Tell your veterinarian if your pet has kidney disease or stomach or intestinal disease. Tell your veterinarian if your pet is pregnant or lactating.

How should Simplicef be given?

Give this medication exactly as directed by your veterinarian. Simplicef should be given with food to increase absorption in the body. Keep plenty of water available for your pet to drink. Do not give Simplicef at the same time as giving antacids such as Maalox or other stomach acid reducers such as Tagamet as this may decrease the absorption of Simplicef. Give all of the Simplicef even if your pet appears to be better. Symptoms may improve before the infection is completely treated. Store tablets at room temperature away from moisture or heat. 

What are the potential side effects of Simplicef?

Stop giving Simplicef and seek emergency veterinary medical care in the event of an allergic reaction (shortness of breath; hives; swelling of the lips, tongue, or face; rash; or fainting), severe nausea, vomiting or diarrhea, mucus or blood in the stool, and unusual bleeding or bruising. Other, less serious side effects such as mild nausea, diarrhea, or yeast infection may be more likely to occur.  Continue to give Simplicef and notify your veterinarian if these symptoms occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Simplicef?

Give the missed dose as soon as you remember. Do not give a double dose unless otherwise directed by your veterinarian.

What happens if I overdose my pet on Simplicef?

Seek emergency veterinary medical treatment if an overdose is suspected. Symptoms of overdose may include nausea, vomiting, diarrhea, and abdominal cramps.

What should I avoid while giving Simplicef to my pet?

Do not give Simplicef at the same time as giving antacids such as Maalox or other stomach acid reducers such as Tagamet.

What other drugs will affect Simplicef?

Before giving Simplicef, tell your veterinarian if your pet is being given another antibiotic (for the same or a different infection), probenecid, a loop diuretic such as furosemide, or warfarin. You may need to have the dosage adjusted. Drugs other than those listed here may also interact with Simplicef. Talk to your veterinarian or pharmacist before giving any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Simplicef Directions:

  • Simplicef is an antibiotic belonging to a class of drugs called cephalosporins that fight bacteria in the body.
  • Simplicef can be used to treat many different types of infections such as bronchitis and pneumonia as well as ear, skin, and urinary tract infections.
Tip:

Simplicef should be given with food to increase absorption by the body.

Simplicef Dosage:

Simplicef Dosage for Dogs
Weight Dosage
All weights Give this medication exactly as directed by your veterinarian. The usual dose of Simplicef in dogs is 2.3-4.5 mg/lb, given by mouth, once a day for 5 to 7 days or 2 to 3 days beyond the cessation of clinical signs, up to a maximum of 28 days.
Simplicef Dosage for Cats
Cats
Do not use!
Simplicef Dosage for Horses
Horses
Do not use!

Storage:

Should be stored in a cool dry place.

Simplicef Ingredients:

Simplicef 100 mg Tablets
Active Ingredient (per tablet) Amount
Cefpodoxime proxetil 100 mg
Simplicef 200 mg Tablets
Active Ingredient (per tablet) Amount
Cefpodoxime proxetil 200 mg

What is Simplicef?

Simplicef is a once-a-day antibiotic used to treat skin infections (wounds and abscesses) caused by susceptible strains of bacteria. Simplicef is an antibiotic belonging to a class of drugs called cephalosporins that fight bacteria in the body. Simplicef can be used to treat many different types of infections such as bronchitis or pneumonia as well as ear, skin, and urinary tract infections. It may also be used for purposes other than those listed. Simplicef requires a prescription from your veterinarian, and is sold per tablet.

For:

Dogs

Benefits:

  • FDA-approved for treating canine bacterial skin infections
  • Simple once-a-day dosing
  • Can be given with or without food
  • Comes in a film-coated tablet for easy administration

How does Simplicef work?

Simplicef is effective against most gram-positive and gram-negative bacteria. Cephalosporin antibiotics suppress the growth of micro-organisms such as bacteria, fungi, or protozoa.

Cautions:

Contact your veterinarian in the event of an allergic reaction (such as shortness of breath, hives, swelling, rash, fainting, vomiting, diarrhea, mucus or blood in the stool, unusual bleeding, or bruising). Do not give Simplicef at the same time as antacids such as Maalox or other stomach acid-reducers, like Tagamet.

Brand Name:

Simplicef (Zoetis), Vantin (Pharmacia and Upjohn)

Generic Name:

Cefpodoxime proxetil

What is the most important thing I should know about Simplicef?

Simplicef is a prescription medication FDA-approved for use in dogs. Simplicef is available as 100 mg elliptical scored tablets and 200 mg tablets that can either be elliptical, unscored tablets marked 5229 or capsule-shaped, scored tablets marked 5229. The usual dose of Simplicef in dogs is 2.3-4.5 mg/lb, given by mouth, once a day for 5 to 7 days or 2 to 3 days beyond the cessation of clinical signs, up to a maximum of 28 days. Simplicef should be given with food to increase absorption by the body. Give all of the Simplicef that is prescribed for your pet. Symptoms may begin to improve before the infection is completely treated.

What should I discuss with my veterinarian before giving Simplicef to my pet?

Tell your veterinarian if your pet has ever had an allergic reaction to another penicillin or to a cephalosporin. Tell your veterinarian if your pet has kidney disease or stomach or intestinal disease. Tell your veterinarian if your pet is pregnant or lactating.

How should Simplicef be given?

Give this medication exactly as directed by your veterinarian. Simplicef should be given with food to increase absorption in the body. Keep plenty of water available for your pet to drink. Do not give Simplicef at the same time as giving antacids such as Maalox or other stomach acid reducers such as Tagamet as this may decrease the absorption of Simplicef. Give all of the Simplicef even if your pet appears to be better. Symptoms may improve before the infection is completely treated. Store tablets at room temperature away from moisture or heat. 

What are the potential side effects of Simplicef?

Stop giving Simplicef and seek emergency veterinary medical care in the event of an allergic reaction (shortness of breath; hives; swelling of the lips, tongue, or face; rash; or fainting), severe nausea, vomiting or diarrhea, mucus or blood in the stool, and unusual bleeding or bruising. Other, less serious side effects such as mild nausea, diarrhea, or yeast infection may be more likely to occur.  Continue to give Simplicef and notify your veterinarian if these symptoms occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Simplicef?

Give the missed dose as soon as you remember. Do not give a double dose unless otherwise directed by your veterinarian.

What happens if I overdose my pet on Simplicef?

Seek emergency veterinary medical treatment if an overdose is suspected. Symptoms of overdose may include nausea, vomiting, diarrhea, and abdominal cramps.

What should I avoid while giving Simplicef to my pet?

Do not give Simplicef at the same time as giving antacids such as Maalox or other stomach acid reducers such as Tagamet.

What other drugs will affect Simplicef?

Before giving Simplicef, tell your veterinarian if your pet is being given another antibiotic (for the same or a different infection), probenecid, a loop diuretic such as furosemide, or warfarin. You may need to have the dosage adjusted. Drugs other than those listed here may also interact with Simplicef. Talk to your veterinarian or pharmacist before giving any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Simplicef Directions:

  • Simplicef is an antibiotic belonging to a class of drugs called cephalosporins that fight bacteria in the body.
  • Simplicef can be used to treat many different types of infections such as bronchitis and pneumonia as well as ear, skin, and urinary tract infections.
Tip:

Simplicef should be given with food to increase absorption by the body.

Simplicef Dosage:

Simplicef Dosage for Dogs
Weight Dosage
All weights Give this medication exactly as directed by your veterinarian. The usual dose of Simplicef in dogs is 2.3-4.5 mg/lb, given by mouth, once a day for 5 to 7 days or 2 to 3 days beyond the cessation of clinical signs, up to a maximum of 28 days.
Simplicef Dosage for Cats
Cats
Do not use!
Simplicef Dosage for Horses
Horses
Do not use!

Storage:

Should be stored in a cool dry place.

Simplicef Ingredients:

Simplicef 100 mg Tablets
Active Ingredient (per tablet) Amount
Cefpodoxime proxetil 100 mg
Simplicef 200 mg Tablets
Active Ingredient (per tablet) Amount
Cefpodoxime proxetil 200 mg