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Product Info
How to Use
Customer Reviews
Product Info

What is Percorten-V?

Percorten-V (desoxycorticosterone pivalate) is the only medication approved by the FDA for treating Canine Addison's Disease (hypoadrenocorticism). Percorten-V is a corticosteroid used to treat conditions in which the body does not produce enough of its own steroids, such as Addison's disease. It may also be used for purposes other than those listed here. Percorten-V requires a prescription from your veterinarian.

You will need a syringe to use Percorten-V, but it is not included in the package. Please see 3cc (3ml) luer slip syringe with 3/4" 25 g Needle.




  • Well tolerated
  • Low incidence of side effects

How does Percorten-V work?

Canine Addison's Disease is a condition where a dog's adrenal glands don't work properly. Normal adrenal glands produce mineralocorticoids that help regulate many bodily functions such as metabolism, blood pressure, and stress response. Percorten-V is a replacement therapy for the mineralocorticoid deficiency in dogs with Addison's disease.


Do not use any preventative vaccines such as Percorten-V without checking with your veterinarian. Talk to your veterinarian about any side effects that seem unusual or bothersome to your pet. Percorten-V should not be stopped suddenly. Percorten-V should not be given to pregnant dogs, or dogs suffering from congestive heart disease, severe renal disease or edema.

Brand Name:

Percorten-V (Novartis)

Generic Name:

Desoxycorticosterone pivalate (DOCP)

What is the most important thing I should know about Percorten-V?

Percorten-V is a prescription medication that is commonly used by veterinarians in dogs for the treatment of Addison's disease. Percorten-V is available as a 4 ml multi-dose vial containing 25 mg/ml. Percorten-V should not be stopped suddenly. Irritation at the injection site may occur. Percorten-V is administered IM (intramuscularly). Do not administer IV (intravenously). Contact the veterinarian if the pet develops behavior changes, swelling, or unusual weight gain.

What should I discuss with my veterinarian before giving Percorten-V to my pet?

Do not give Percorten-V to your pet if the pet has a serious bacterial, viral or fungal infection. Percorten-V weakens the pet's immune response and its ability to fight infections. Tell your veterinarian if your pet has kidney or liver disease, heart disease, stomach ulcers, hypothyroidism, diabetes mellitus or any other medical conditions. Also tell your veterinarian if the pet is pregnant or lactating.

How should Percorten-V be given?

Give this medication exactly as directed by your veterinarian. Do not give more or less than is prescribed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. The usual dose of Percorten-V in dogs is 1mg/pound given by IM injection every 25 days. Store Percorten-V at room temperature away from moisture and heat. Keep this medication away from children and pets.

What are the potential side effects of Percorten-V?

If any of the following serious side effects occur, stop giving Percorten-V and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), increased blood pressure or sudden weight gain. Other less serious side effects may occur. Continue giving Percorten-V and talk to your veterinarian if your pet experiences insomnia, nausea, vomiting or stomach upset, fatigue, muscle weakness or joint pain, problems with diabetes control or increased hunger or thirst. Other side effects that occur rarely, usually with high doses of Percorten-V include thinning of the skin, cataracts, glaucoma, behavior changes. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Percorten-V?

Give the missed dose as soon as you remember. However, if it almost time for the next dose, skip the dose missed and give only the next regularly scheduled dose. Do not give a double dose of this medication.

What happens if I overdose my pet on Percorten-V?

Seek emergency veterinary medical treatment. Symptoms of overdose may include swelling or water retention, high blood pressure, weight gain, low levels of potassium in the blood, and Cushing's disease.

What should I avoid while giving Percorten-V to my pet?

Avoid sources of infection. Do not use any preventative vaccines without checking with the veterinarian.

What other drugs will affect Percorten-V?

Do not give any other over the counter or prescription medications, including herbal products, during treatment with Percorten-V without first talking to the veterinarian. Tell your veterinarian if your pet is taking Phenobarbital, furosemide, insulin or glipizide, phenytoin, digoxin, warfarin, or aspirin. Drugs other than those listed may interact with Percorten-V resulting in side effects or altered effectiveness.

How to Use

Percorten-V Directions:

  • Percorten-V is a prescription medication that is commonly used by veterinarians in dogs for the treatment of Addison's disease.
  • Percorten-V is a corticosteroid used to treat conditions, such as Addison's disease, in which the body does not produce enough of its own steroids.
  • Percorten-V is available as a 4 ml multi-dose vial containing 25 mg/ml and is administered IM (intramuscularly). Do not administer IV (intravenously).

Percorten-V should not be stopped suddenly. Irritation at the injection site may occur.

All weights
Shake well before using. Give 1 mg/lb of body weight by IM (intramuscular) injection every 25 days
Do not use!
Do not use!

Store this product at room temperature, away from moisture and heat.


Percorten-V Ingredients:

Active Ingredients (per ml)
Desoxycorticosterone Pivalate
25 mg
10.5 mg
Sodium Carboxymethylcellulose
3 mg
Polysorbate 80
1 mg
Sodium Chloride
8 mg
Thimerosal (a preservative)
Customer Reviews
Percorten-V is rated 4.9 out of 5 by 40.
Rated 5 out of 5 by from Amazing Chloe has been using her pecorten-v monthly and she is again a happy healthy dog!
Date published: 2017-02-26
Rated 5 out of 5 by from Percorten-V Gold Standard Tx for A-dogs My dog was diagnosed 28 months ago after being in critical condition. When I heard about Percorten-V I told the Vet I wanted to switch and I would give the injection myself, along with a daily small replacement dose of Prednisone. It was definitely the BEST move we made with her treatment, and by far the most cost effective on the "Low Dose Protocol". She will be 4 years old next month and her electrolytes are perfect. She's 100% normal and living a healthy, happy life!
Date published: 2017-02-14
Rated 5 out of 5 by from Percorten Chloe my chihuahua mix rescue was diagnosed with Addisons recently. I called 1800petmeds to ask questions before I purchased. The young lady was so helpful & answered all my questions. The medication arrived promptly.....actually a day before the scheduled time. Chloe's condition has improved drastically since her 1st injection. I couldn't t be happier with this medication & 1800petmeds. I will definitely keep ordering from y'all.
Date published: 2017-02-08
Rated 5 out of 5 by from Every time I order from 800petmeds(I order once a month) ...they are always polite/helpful/quick to get my med's to me... I highly recommend them! While I order several things... the percorten is of great importance for my dogs survival...the med is high quality and works perfect!
Date published: 2016-12-19
Rated 5 out of 5 by from Percorten V I bought this product for my Westie due to her having Addison's Disease. My Vet is over a half hour away from my home and it was more expensive to buy it from my Vet then to get the great discount I received from Pet Meds and it was delivered right to my door. Thank you Pet Meds!!
Date published: 2016-11-06
Rated 5 out of 5 by from great product My pomeranian/dashaund dog piglet has addison disease and i could not see myself putting him to sleep so i asked our vet if there was something i could give him and he said percortenv and ever since i gave him his injections every month he has been alot better thankyou 1800petmeds for keeping my dog alive
Date published: 2016-02-29
Rated 5 out of 5 by from This product keeps my dog alive! My Boston Terrier dog has Addison's Disease, and he would not be alive if not for monthly Percorten-V injections! At 1-800-PetMeds, I can get this for about a hundred dollar less then at my Vet's office!
Date published: 2015-05-01
Rated 5 out of 5 by from great product/ great price Maggie was diagnosed with Addison's disease and has responded very well to her treatment. She is on Percorten (every 25 days) and Prednisone (daily). It is very helpful to be able to purchase her medications at a better price through PetMeds, especially given that this is a treatment for life. She is a medium dog (30 lbs) so we save about $250 a year when purchasing through PetMeds than through other pharmacies. Thank you!
Date published: 2015-04-19
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have a 10% dsct coupon, but can see when it expires .. pls advise

Asked by: sara
Please contact our sales department for pricing information.
Answered by: S Duesler PharmD MBA
Date published: 2016-11-17

Can per item be shipped to Canada

Asked by: Anonymous
Yes. There is a $14.99 shipping charge to ship to Canada.
Answered by: Christine
Date published: 2016-10-22

If you accidentally give your dog their shot a week apart will they get sick?

Asked by: Diane
Overdosing your pet may cause polyuria (frequent urination), polydipsia (increased thirst), high sodium levels, high blood pressure, edema (swelling due to fluid retention), and low potassium. Excessive weight gain may be indicative of fluid retention secondary to sodium retention. If your dog is acting different or seems sick or lethargic call your vet; electrolytes may be off and may need to be monitored.
Answered by: Christine
Date published: 2016-09-28

My dog has Addisons and weighs 85 lbs

My dog weighs 85 lbs. If I get this bottle of 4 ML and she gets 1mg per LB, she will get 3.4 ml per shot correct?
Asked by: Anonymous
Please consult your veterinarian regarding dosing for your pet.
Answered by: S Duesler PharmD MBA
Date published: 2016-07-09

Does this drug stimulate hair growth?

Percorten-V Since our dog has received this medication she is doing much better. The question I have is does it cause hair growth? She has grown hair on her belly that she has never had before and other places. Thank you.
Asked by: Anonymous
No, no more than before the starting Percorten.
Answered by: Anonymous
Date published: 2015-05-01

How does percorten compare to flurodrocortizone

What is the difference in these two drugs for dogs with Addisons?
Asked by: Anonymous
They both are used to treat Addisons. The main difference is that the Percorten is injectable and given at intervals that can range from 3 to 4 weeks while the fludrocortisone is an oral tablet that is usually given daily or a few days each week.
Answered by: Anonymous
Date published: 2015-04-09


How much comes in a bottle of percorten? And how many doses?
Asked by: Anonymous
4 mL comes in one bottle. My dog originally got a shot of 2.4 mL when she was first diagnosed. Now I have her electrolytes tested every month and her dose is now at 1.6 mL. My vet has been dropping it by approximately .2mL a month. However, I will keep testing her electrolytes until I find out her ideal, low dosage.
Answered by: Anonymous
Date published: 2016-07-09

Once percorten-v is opened how many doses can I give him

I was told by Novartis that after two months (I give the Percorten-v every 28 days) I must get a new bottle. Please help.
Asked by: Anonymous
My dog's a Min Pin who's been on .57 of it for 6 yrs & his vet is one of my best friends. I get 5 doses give or take (due to drawing wrong occasionally & losing a little to squirting) The last dose of the bottle (5 mos) shows the very obvious boost & that little "fountain of youth" effect I see if he's been especially stressed after the 25 day post dose, then I know the signs that it's time early or not to give him his shot on the 25th day. But that is just what my Friend/Vet told me to do. He also said if he shows none of what are his clear signs, HE (MY DOG) can even go a day or two past 30th day (perhaps because of his size. I know exactly when I have no more than two days to give him that shot based on quite a few signs. It varies with how much stress or excitement he's had when close to the regular 30 day mark. If I see the "signs" I'll give it to him even if it's only been 23 days since last dose. *This is what my Vet has supervised for many years but my kid like all is not like any other so always make sure your Vet agrees. Of course a drug company would say that. One thing my friend/Vet was always fastidious about when he was doing the injection was he shakes the bottle for a really long time, at least a minute or two. (Make sure there's no sign of powder at the bottom when you turn the vial over) I keep it in the fridge & find that it's easier to shake if you take it out 15 mins or so & let it get to room temperature *following the drugs included leaflet instructions as to the temperatures which are safe for it to be stored at. It's OK up to 80 degrees I believe - but don't rely on me.
Answered by: Anonymous
Date published: 2013-10-22
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