K9 Advantix II

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What is K9 Advantix II?

K9 Advantix II is a monthly preventative for dogs that offers comprehensive protection against ticks, fleas, mosquitoes, biting flies, and chewing lice. K9 Advantix II is a top veterinarian-recommended brand because it repels and kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks). K9 Advantix II kills 98-100 percent of fleas within 12 hours and continues working for one month to prevent infestations. Fleas and ticks are killed on contact with a treated dog, which means that fleas don't have to bite and ticks don't have to attach to die. This helps prevent transmission of flea-borne and tick-borne diseases such as tapeworms, Lyme disease, tick paralysis, ehrlichia, and Rocky Mountain spotted fever. Killing fleas before they bite may also help prevent skin allergies caused by flea saliva. As well, K9 Advantix II repels mosquitoes before they bite, which may help prevent transmission of heartworms. K9 Advantix II protects your pet before parasites have a chance to bite, not after.

For:

Dogs and Puppies (7+ weeks of age, weighing 4+ lbs)

Benefits:

  • Repels and kills disease-carrying fleas, ticks, and mosquitoes before they bite
  • Kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks)
  • Kills 98-100 percent of adult fleas within 12 hours
  • Ends flea life cycle by preventing flea offspring (eggs, pupae, and larvae) from maturing into adult fleas
  • Repels biting flies and kills chewing lice
  • Provides one month of protection against ticks, fleas, mosquitoes, biting flies
  • Waterproof - remains effective following a shampoo treatment, swimming or after exposure to rain or sunlight

How does K9 Advantix II work?

K9 Advantix II combines imidacloprid and permethrin to repel and kill fleas, ticks, and mosquitoes. Both ingredients work on contact, attacking parasite nerve cells at different sites. Together these ingredients overwhelm the nervous system killing the parasite. Pyriproxyfen is an insect growth regulator. K9 Advantix II topical solution also repels biting flies and kills lice.

Cautions:

DO NOT USE ON CATS. Cats cannot metabolize the ingredients used in this product. Cats must be separated from dogs during treatment. Do not allow your cat to come in contact with a treated dog for 24 hours. Some small and medium dogs may have an adverse skin reaction.

Brand Name:

K9 Advantix II (Elanco)

What is the most important thing I should know about K9 Advantix II?

The active ingredients in K9 Advantix II are Imidacloprid (8.8%), Permethrin (44.0%), and Pyriproxyfen (0.44%). K9 Advantix II is for use on dogs and puppies weighing 4 lbs or more and 7 weeks of age or older. It is used for the topical prevention and treatment of ticks, fleas, mosquitoes, biting flies, and chewing lice on dogs. K9 Advantix II repels and kills ticks including deer ticks (the major carrier of Lyme disease), American dog ticks, Brown dog ticks and lone star ticks. Additionally, K9 Advantix II repels and kills all life stages of fleas, repels and kills mosquitoes, kills chewing lice, and repels biting flies. K9 Advantix II is a non-prescription (OTC) product available as 0.014 fl oz (0.4 ml) applicators for dogs 4-10 lbs (Green), 0.034 fl oz (1.0 ml) applicators for dogs 11-20 lbs (Teal), 0.084 fl oz (2.5 ml) applicators for dogs 21-55 lbs (Red), and 0.135 fl oz (4.0 ml) applicators for dogs over 55 lbs (Blue).

What should I discuss with my veterinarian before giving K9 Advantix II to my pet?

Consult a veterinarian before using on medicated animals and debilitated, aged, pregnant or nursing animals.

How should K9 Advantix II be applied?

For use only on dogs. Do not use on cats or on other animals. Have your dog stand for easy application. Part the hair on your dog's back between the shoulder blades, until the skin is visible. For dogs up to 20 lbs, apply the entire contents of the applicator tube to 2 or 3 spots on the top of the back from the shoulder to the base of the tail. For dogs 21 lbs and over, apply the entire contents of the applicator tube to 4 or 6 spots on the top of the back from the shoulder to the base of the tail. If your household has cats or other pets, separate them from the treated dog for 24 hours.

What are the potential side effects of K9 Advantix II?

Monitor your dog after application. Side effects may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects (such as lethargy or agitation) occur, consult your veterinarian or call 1-800-422-9874. Individual sensitivities, while rare, may occur after using any pesticide product for pets. A small percentage of dogs have had adverse reactions to K9 Advantix II. A sensation of burning, tingling, itching, redness or numbness of the skin may occur after topical application. This sensation usually begins 1-2 hours after application. In addition, reactions have occurred in cats that have been exposed to a medicated dog. That is why it is important to separate your cat from a medicated dog for 24 hours. Elanco, the manufacturer of K9 Advantix II, indicates that some of these symptoms will dissipate within 48 hours; however, if your pet is experiencing adverse reactions, please complete the following steps:

  • Stop applying the medication
  • Wash your dog with a detergent based soap (Dawn or Palmolive dish detergents work best). Do not scrub the affected area, as this may cause more skin irritation. Please note: This process is applicable for both dogs and cats.
  • Call your veterinarian
  • Call Elanco Emergency Support Line at 1-800-422-9874. Let Elanco know your dog is having an adverse reaction to K9 Advantix by calling 1-800-422-9874. This line is staffed 24 hours a day, 7 days a week.

What happens if I miss giving a dose of K9 Advantix II?

If you miss a dose, apply the next dose as soon as possible and resume a monthly schedule.

What happens if I overdose my pet on K9 Advantix II?

Contact your veterinarian or veterinary emergency room.

What should I avoid while giving K9 Advantix II to my pet?

This product is for external use only on dogs and puppies 4 lbs or more and 7 weeks or older. Do not get this product in your dog's eyes or mouth. Do not use this product on animals other than dogs. In households with cats, separate the treated dog for about 24 hours. Due to their unique physiology and inability to metabolize certain compounds, this product must not be used on cats. If applied to a cat, or ingested by a cat which actively grooms a recently treated dog, this product may have serious harmful effects. If this occurs, contact your veterinarian immediately. It is important to apply this product no more than once a month and to use the correct strength for the weight of the dog. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have the patient sip water. Do not induce vomiting unless advised to and the patient is conscious. This product can cause substantial but temporary eye injury. Do not get in eyes or on skin or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse..

What other drugs will affect K9 Advantix II?

If your pet is on medication, consult your veterinarian before using this or any other product.

K9 Advantix II Directions:

HOW TO OPEN

  1. Be sure the tube is at the bottom of the pouch.
  2. Using scissors, cut the pouch across the top and remove the tube.

HOW TO APPLY

  1. Use only on Dogs. DO NOT USE ON CATS or other animals.
  2. Do not apply to dogs weighing less than 4 lbs.
  3. Remove the applicator tube from the package. Use scissors to peel down foil.
  4. Hold the applicator tube in an upright position. Pull the cap off the tube.
  5. Turn the cap around and place the other end of the cap back on the tube.
  6. Your dog should be standing for easy application. Evenly apply the entire contents of the K9 Advantix II tube to two or three spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of your dog. Do not get this product in your dog's eyes or allow your dog to ingest this product.
  7. Discard the empty tube as described in Storage and Disposal.
  8. In cases of severe pest infestations, retreatment is allowable earlier than four (4) weeks. Do not retreat more of often than once every seven (7) days. After pest control is attained, return to a monthly retreatment schedule.
Tip:

In households with cats, separate the treated dog for 24 hours until the product is thoroughly dry.

K9 Advantix II Dosage for Dogs:

Dogs/Puppies (7+ weeks of age, weighing 4+ lbs):
Weight Amount
1-3 lbs Do not use
4-10 lbs Apply contents of 1 applicator once a month (Green Box)
11-20 lbs Apply contents of 1 applicator once a month (Teal Box)
21-55 lbs Apply contents of 1 applicator once a month (Red Box)
Over 55 lbs Apply contents of 1 applicator once a month (Blue Box)
K9 Advantix II Dosage for Cats:
Cats
Do not use!
K9 Advantix II Dosage for Horses:
Horses
Do not use!

Storage:

Do not contaminate water, food or feed by storage or disposal.

Environmental Hazards:

This product is extremely toxic to aquatic organisms, including fish and invertebrates. Do not add directly to water. Do not contaminate water when disposing of product or packaging.

Pesticide Storage:

Store K9 Advantix II in a cool, dry place. Protect from freezing.

Pesticide Disposal and Container Handling:

Nonrefillable container.

If empty:

Do not reuse this container. Place in trash or offer for recycling, if available.

If partly filled:

Call your local solid waste agency or 1-800-422-9874 for disposal instructions. Never place unused product down any indoor or outdoor drain.

Do not refrigerate. Store in the original container only. Do not reu

K9 Advantix II Ingredients:

K9 Advantix II for Dogs 4-10 lbs (Small Dog - Green Box) (0.4 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 11-20 lbs (Medium Dog - Teal Box) (1.0 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 21-55 lbs (Large Dog - Red Box) (2.5 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs over 55 lbs (Extra Large Dog - Blue Box) (4.0 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
Product Details Product Details

What is K9 Advantix II?

K9 Advantix II is a monthly preventative for dogs that offers comprehensive protection against ticks, fleas, mosquitoes, biting flies, and chewing lice. K9 Advantix II is a top veterinarian-recommended brand because it repels and kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks). K9 Advantix II kills 98-100 percent of fleas within 12 hours and continues working for one month to prevent infestations. Fleas and ticks are killed on contact with a treated dog, which means that fleas don't have to bite and ticks don't have to attach to die. This helps prevent transmission of flea-borne and tick-borne diseases such as tapeworms, Lyme disease, tick paralysis, ehrlichia, and Rocky Mountain spotted fever. Killing fleas before they bite may also help prevent skin allergies caused by flea saliva. As well, K9 Advantix II repels mosquitoes before they bite, which may help prevent transmission of heartworms. K9 Advantix II protects your pet before parasites have a chance to bite, not after.

For:

Dogs and Puppies (7+ weeks of age, weighing 4+ lbs)

Benefits:

  • Repels and kills disease-carrying fleas, ticks, and mosquitoes before they bite
  • Kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks)
  • Kills 98-100 percent of adult fleas within 12 hours
  • Ends flea life cycle by preventing flea offspring (eggs, pupae, and larvae) from maturing into adult fleas
  • Repels biting flies and kills chewing lice
  • Provides one month of protection against ticks, fleas, mosquitoes, biting flies
  • Waterproof - remains effective following a shampoo treatment, swimming or after exposure to rain or sunlight

How does K9 Advantix II work?

K9 Advantix II combines imidacloprid and permethrin to repel and kill fleas, ticks, and mosquitoes. Both ingredients work on contact, attacking parasite nerve cells at different sites. Together these ingredients overwhelm the nervous system killing the parasite. Pyriproxyfen is an insect growth regulator. K9 Advantix II topical solution also repels biting flies and kills lice.

Cautions:

DO NOT USE ON CATS. Cats cannot metabolize the ingredients used in this product. Cats must be separated from dogs during treatment. Do not allow your cat to come in contact with a treated dog for 24 hours. Some small and medium dogs may have an adverse skin reaction.

Brand Name:

K9 Advantix II (Elanco)

What is the most important thing I should know about K9 Advantix II?

The active ingredients in K9 Advantix II are Imidacloprid (8.8%), Permethrin (44.0%), and Pyriproxyfen (0.44%). K9 Advantix II is for use on dogs and puppies weighing 4 lbs or more and 7 weeks of age or older. It is used for the topical prevention and treatment of ticks, fleas, mosquitoes, biting flies, and chewing lice on dogs. K9 Advantix II repels and kills ticks including deer ticks (the major carrier of Lyme disease), American dog ticks, Brown dog ticks and lone star ticks. Additionally, K9 Advantix II repels and kills all life stages of fleas, repels and kills mosquitoes, kills chewing lice, and repels biting flies. K9 Advantix II is a non-prescription (OTC) product available as 0.014 fl oz (0.4 ml) applicators for dogs 4-10 lbs (Green), 0.034 fl oz (1.0 ml) applicators for dogs 11-20 lbs (Teal), 0.084 fl oz (2.5 ml) applicators for dogs 21-55 lbs (Red), and 0.135 fl oz (4.0 ml) applicators for dogs over 55 lbs (Blue).

What should I discuss with my veterinarian before giving K9 Advantix II to my pet?

Consult a veterinarian before using on medicated animals and debilitated, aged, pregnant or nursing animals.

How should K9 Advantix II be applied?

For use only on dogs. Do not use on cats or on other animals. Have your dog stand for easy application. Part the hair on your dog's back between the shoulder blades, until the skin is visible. For dogs up to 20 lbs, apply the entire contents of the applicator tube to 2 or 3 spots on the top of the back from the shoulder to the base of the tail. For dogs 21 lbs and over, apply the entire contents of the applicator tube to 4 or 6 spots on the top of the back from the shoulder to the base of the tail. If your household has cats or other pets, separate them from the treated dog for 24 hours.

What are the potential side effects of K9 Advantix II?

Monitor your dog after application. Side effects may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects (such as lethargy or agitation) occur, consult your veterinarian or call 1-800-422-9874. Individual sensitivities, while rare, may occur after using any pesticide product for pets. A small percentage of dogs have had adverse reactions to K9 Advantix II. A sensation of burning, tingling, itching, redness or numbness of the skin may occur after topical application. This sensation usually begins 1-2 hours after application. In addition, reactions have occurred in cats that have been exposed to a medicated dog. That is why it is important to separate your cat from a medicated dog for 24 hours. Elanco, the manufacturer of K9 Advantix II, indicates that some of these symptoms will dissipate within 48 hours; however, if your pet is experiencing adverse reactions, please complete the following steps:

  • Stop applying the medication
  • Wash your dog with a detergent based soap (Dawn or Palmolive dish detergents work best). Do not scrub the affected area, as this may cause more skin irritation. Please note: This process is applicable for both dogs and cats.
  • Call your veterinarian
  • Call Elanco Emergency Support Line at 1-800-422-9874. Let Elanco know your dog is having an adverse reaction to K9 Advantix by calling 1-800-422-9874. This line is staffed 24 hours a day, 7 days a week.

What happens if I miss giving a dose of K9 Advantix II?

If you miss a dose, apply the next dose as soon as possible and resume a monthly schedule.

What happens if I overdose my pet on K9 Advantix II?

Contact your veterinarian or veterinary emergency room.

What should I avoid while giving K9 Advantix II to my pet?

This product is for external use only on dogs and puppies 4 lbs or more and 7 weeks or older. Do not get this product in your dog's eyes or mouth. Do not use this product on animals other than dogs. In households with cats, separate the treated dog for about 24 hours. Due to their unique physiology and inability to metabolize certain compounds, this product must not be used on cats. If applied to a cat, or ingested by a cat which actively grooms a recently treated dog, this product may have serious harmful effects. If this occurs, contact your veterinarian immediately. It is important to apply this product no more than once a month and to use the correct strength for the weight of the dog. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have the patient sip water. Do not induce vomiting unless advised to and the patient is conscious. This product can cause substantial but temporary eye injury. Do not get in eyes or on skin or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse..

What other drugs will affect K9 Advantix II?

If your pet is on medication, consult your veterinarian before using this or any other product.

K9 Advantix II Directions:

HOW TO OPEN

  1. Be sure the tube is at the bottom of the pouch.
  2. Using scissors, cut the pouch across the top and remove the tube.

HOW TO APPLY

  1. Use only on Dogs. DO NOT USE ON CATS or other animals.
  2. Do not apply to dogs weighing less than 4 lbs.
  3. Remove the applicator tube from the package. Use scissors to peel down foil.
  4. Hold the applicator tube in an upright position. Pull the cap off the tube.
  5. Turn the cap around and place the other end of the cap back on the tube.
  6. Your dog should be standing for easy application. Evenly apply the entire contents of the K9 Advantix II tube to two or three spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of your dog. Do not get this product in your dog's eyes or allow your dog to ingest this product.
  7. Discard the empty tube as described in Storage and Disposal.
  8. In cases of severe pest infestations, retreatment is allowable earlier than four (4) weeks. Do not retreat more of often than once every seven (7) days. After pest control is attained, return to a monthly retreatment schedule.
Tip:

In households with cats, separate the treated dog for 24 hours until the product is thoroughly dry.

K9 Advantix II Dosage for Dogs:

Dogs/Puppies (7+ weeks of age, weighing 4+ lbs):
Weight Amount
1-3 lbs Do not use
4-10 lbs Apply contents of 1 applicator once a month (Green Box)
11-20 lbs Apply contents of 1 applicator once a month (Teal Box)
21-55 lbs Apply contents of 1 applicator once a month (Red Box)
Over 55 lbs Apply contents of 1 applicator once a month (Blue Box)
K9 Advantix II Dosage for Cats:
Cats
Do not use!
K9 Advantix II Dosage for Horses:
Horses
Do not use!

Storage:

Do not contaminate water, food or feed by storage or disposal.

Environmental Hazards:

This product is extremely toxic to aquatic organisms, including fish and invertebrates. Do not add directly to water. Do not contaminate water when disposing of product or packaging.

Pesticide Storage:

Store K9 Advantix II in a cool, dry place. Protect from freezing.

Pesticide Disposal and Container Handling:

Nonrefillable container.

If empty:

Do not reuse this container. Place in trash or offer for recycling, if available.

If partly filled:

Call your local solid waste agency or 1-800-422-9874 for disposal instructions. Never place unused product down any indoor or outdoor drain.

Do not refrigerate. Store in the original container only. Do not reu

K9 Advantix II Ingredients:

K9 Advantix II for Dogs 4-10 lbs (Small Dog - Green Box) (0.4 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 11-20 lbs (Medium Dog - Teal Box) (1.0 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 21-55 lbs (Large Dog - Red Box) (2.5 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs over 55 lbs (Extra Large Dog - Blue Box) (4.0 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
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