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$1.57 $1.07 per tablet
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0.1 mg (sold per tablet)
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$1.57 $1.07 per tablet
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Product Info
What is Fludrocortisone?

Fludrocortisone is used by veterinarians in the treatment of Addison's Disease. Fludrocortisone requires a prescription from your veterinarian, and is sold per tablet.


Cats and Dogs

  • Easy to administer
  • Once a day dosing, typically
How it Works:

Fludrocortisone acetate is a mineralocorticoid, similar in action to aldosterone, which acts on the kidney to help balance the concentration of sodium and potassium in your pet's body.


If your pet experiences increased blood pressure, sudden weight gain, difficulty breathing, hives, or swelling of the lips, tongue or face, stop giving Fludrocortisone and seek emergency veterinary medical attention.

Brand Name:

Florinef (Bristol-Myers Squibb)

Generic Name:

Fludrocortisone (flew-dro-cort'-ih-zone)

What is Fludrocortisone:

Fludrocortisone is a corticosteroid used to treat conditions in which the body does not produce enough of its own steroids, such as Addison's disease. Fludrocortisone may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving fludrocortisone to my pet:

Do not give fludrocortisone to your pet if the pet has a serious bacterial, viral or fungal infection. Fludrocortisone weakens the pet's immune response and its ability to fight infections. Tell your veterinarian if your pet has kidney or liver disease, heart disease, stomach ulcers, hypothyroidism, diabetes mellitus or any other medical conditions. Also tell your veterinarian if the pet is pregnant or lactating.

What is the most important information I should know about fludrocortisone:

Fludrocortisone is a prescription medication that is commonly used by veterinarians in dogs and cats for the treatment of Addison's disease. Fludrocortisone is available as 0.1mg scored tablets. Fludrocortisone should not be stopped suddenly. There should be a gradual reduction in dosage before stopping. Fludrocortisone should be taken with food to lessen stomach upset. Contact the veterinarian if the pet develops behavior changes, swelling, or unusual weight gain.

What happens if I miss giving a dose:

Give the missed dose as soon as you remember. However, if it almost time for the next dose, skip the dose missed and give only the next regularly scheduled dose. Do not give a double dose of this medication.

What should I avoid while giving Fludrocortisone to my pet:

Avoid sources of infection. Do not use any vaccines without checking with the veterinarian.

What are the possible side effects of Fludrocortisone:

If any of the following serious side effects occur, stop giving fludrocortisone and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), increased blood pressure or sudden weight gain. Other less serious side effects may occur. Continue giving fludrocortisone and talk to your veterinarian if your pet experiences insomnia, nausea, vomiting or stomach upset, fatigue, muscle weakness or joint pain, problems with diabetes control or increased hunger or thirst. Other side effects that occur rarely, usually with high doses of fludrocortisone include thinning of the skin, cataracts, glaucoma, behavior changes. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

What other drugs will affect Fludrocortisone:

Do not give any other over the counter or prescription medications, including herbal products, during treatment with fludrocortisone without first talking to the veterinarian. Tell your veterinarian if your pet is taking Phenobarbital, furosemide, insulin or glipizide, phenytoin, digoxin, warfarin, or aspirin. Drugs other than those listed may interact with fludrocortisone resulting in side effects or altered effectiveness.

Where can I get more information:

Your pharmacist has additional information about Fludrocortisone written for health professionals that you may read.

Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.

How to Use
  • Fludrocortisone is a corticosteroid available by prescription used to treat conditions in which the body does not produce enough of its own steroids, such as Addison's disease.
  • Do not give fludrocortisone to your pet if the pet has serious bacterial, viral, or fungal infection. Fludrocortisone weakens the pet's immune response and its ability to fight infections.
  • Give this medication exactly as directed by your veterinarian. Do not give more or less than is prescribed by your veterinarian.

Keep plenty of water available for the pet to drink. Fludrocortisone should be given with food. Do not stop giving this medication suddenly if the pet has been on the medication for a few weeks. A gradual reduction in dosage may be required before stopping this medication.

All weights
The usual dose is 0.009mg per pound of pet's body weight once daily with food
All weights
The usual dose is 0.1mg once daily with food
Do not use!

Store this product at room temperature.

Fludrocortisone Acetate Tablet:
Active Ingredient
Fludrocortisone Acetate
0.1 mg
Customer Reviews
Fludrocortisone is rated 5.0 out of 5 by 1.
Rated 5 out of 5 by from Great product, highly recommend Marley has been taking Fludrocortisone for 6 months and is doing very well. He takes a half a pill every 12hrs. He has Addison's and Fludrocortisone has balanced and maintained his levels very well. Without this medicine Marley would not be with us any longer so this has saved his life.
Date published: 2013-06-18
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My vet wants to stop fluorine and start him on injections each month what are the risks for him.

Asked by: Ernie
Taking a steroid injection once monthly versus a steroid pill daily comes with the same side effects and risks. However, your pet may experience an injection site reaction, such as pain, swelling, and redness, which is rare, but can occur with any injection,. If you have any concerns, speak with your veterinarian. Taking a monthly injection may work better for some animals, while taking an oral pill daily may work better for others.
Answered by: Christine
Date published: 2017-02-19

Florinef as it was sold in the UK is being discontinued due to the license running out and a new injectable drug being released specifically for dogs.  Is this tablet you are selling readily available and still being manufactured?

Asked by: Gina1970
Yes, fludrocortisone is still available.
Answered by: Christine
Date published: 2016-10-11

Is $1,19 the price per tablet or per 100 tablets?

Asked by: Jorge Mtnez
That is the sale price per tablet for now however the price does vary.
Answered by: Lilli Pharmacist
Date published: 2015-09-22

My dog will be taking Fludrocortisone for the rest of his life.

My Great Dane was prescribed Fludrocortisone for the treatment of addison's disease. Because of his weight, he was prescribed 0.6 MG cap. Can you match the dosage and at what price? I can obtain a prescription from my vet when necessary.
Asked by: eestubbs
Unfortunately we do not carry this strength. Please check with your veterinarian or local pharmacy.
Answered by: S Duesler PharmD MBA
Date published: 2015-03-26

Can fludrocortisone make a dog itchy and lose hair?

Asked by: Cathy
This is not a usual side effect of this medication. If you do notice this when using the medication on your pet let you veterinarian know right away.
Answered by: Cheryl-Pharmacist
Date published: 2017-02-21

I have an Addison's dog that takes .75mg of Fludrocortisone. I just accidentally gave the pill to my healthy 65lb dog. Will this dog be ok?

Asked by: bg
Please consult with your veterinarian.
Answered by: Lilli Pharmacist
Date published: 2017-02-19

Abatement of symptoms

My dog has been on florinef for nearly one month. He is being treated for iotregenic Addison's and is doing infinitely better - thankfully. He is almost back to normal with the exception of his continued polydipsia and polyuria. How long before those symptoms subside? His electrolytes are approaching normal and he'll have an ATCH test in month to see if the Addison's is staying or if he'll revert back to Cushings. I'm just curious as to how long the symptoms will last. It's rainy season in southern Japan so going out every hour or so is not fun for anyone. Thank you.
Asked by: RowerChick
It is difficult to say how long the symptoms will last but once his electrolytes and ACTH tests are normal then the symptoms should subside.
Answered by: Janine M./Pharmacist
Date published: 2017-02-19

percorten & florinef together

if my dog had a percorten injection and then doubled the dose of florinef and doubled her dose of prednisone and then put her on an iv na/cl fluids for 28 hours.....all this because her na was a bit low....and my dog is epileptic and on phenobarbitol....could this cause problems?
Asked by: jenna
Percorten and Florinef may be given together. Percorten should be used with caution along with certaiin drugs such as Phenobarbital. Further discussion with your veterinarian is recommended.
Answered by: Lisa M
Date published: 2017-02-19
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