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Clomicalm

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Product Info

What is Clomicalm?

Clomicalm (clomipramine) is used to treat separation anxiety in dogs in connection with behavior modification and training. This medication affects chemicals in the brain that may become unbalanced leading to behavioral problems in dogs. Clomicalm requires a prescription from your veterinarian.

For:

Dogs (6+ months of age)

Benefits:

  • Treats separation anxiety in dogs
  • Helps reduce symptoms caused by separation anxiety such as, excessive barking, inappropriate elimination, and other destructive tendencies
  • It is not a tranquilizer or a sedative, and should not affect your dog's personality or memory

How does Clomicalm work?

Clomicalm (clomipramine) is a tricyclic antidepressant that affects chemicals in the brain (serotonin) that may become unbalanced leading to behavioral problems in dogs. Clomicalm treats separation anxiety in dogs. Separation anxiety is, in many cases, the root cause of behaviors such as excessive barking, inappropriate elimination, and other destructive tendencies. When used in conjunction with a training program, Clomicalm may be used to help decrease or eliminate these behaviors by helping treat the root cause.

Cautions:

Don't use Clomicalm if your pet is taking a monoamine oxidase inhibitor (MAOI) such as Anipryl, or selegiline, or has been using a Preventic Collar in the last 14 days. Clomicalm may increase the effects of other drugs and may cause drowsiness. Stop giving your pet Clomicalm and contact your vet if your pet displays any of the following reactions: difficulty breathing, hives, irregular heartbeat, difficulty urinating, seizures, fever with increased panting, muscle stiffness or weakness, or swelling of the lips, tongue, or face.

Brand Name:

Anafranil (Novartis), Clomicalm (Novartis)

Generic Name:

Clomipramine (klo-mip'-ra-meen)

What is the most important thing I should know about Clomicalm?

Clomicalm is a prescription medication FDA approved for veterinary use in dogs. Clomicalm is available as 20 mg, 40 mg and 80 mg tablets. The usual dose of Clomicalm in dogs is 0.5-1.5 mg/lb every 24 hours. Clomicalm may also be useful in cats, but cats tend to be more sensitive to tricyclic antidepressant drugs. Dosing of cats may be difficult with the commercially available products. Clomicalm may not help symptoms right away. It may take a number of days before symptoms begin to lessen. Contact your veterinarian if symptoms get worse or if new symptoms develop while your pet is on this medication. Clomicalm may cause drowsiness or dizziness.

What should I discuss with my veterinarian before giving Clomicalm to my pet?

Do not give this medication if your pet has taken or used a monoamine oxidase inhibitor (MAOI) such as selegiline, Mitaban Dip or Preventic Collar within the last 14 days. Tell your veterinarian if your pet has liver or kidney disease, asthma, thyroid disease, diabetes, stomach or intestinal problems, high blood pressure or heart disease, difficulty urinating, seizures, or glaucoma. Tell your veterinarian if your pet is pregnant or lactating.

How should Clomicalm be given?

Give this medication exactly as directed by your veterinarian. Allow your pet to drink plenty of water. If you do not understand the directions, ask your pharmacist or veterinarian to explain them to you. Store Clomicalm at room temperature away from moisture and heat. Keep this medication away from children and pets.

What are the potential side effects of Clomicalm?

If any of the following serious side effects occur, stop giving Clomicalm and seek emergency veterinary medical attention: an allergic reaction (difficulty breathing, swelling of the lips, tongue or face, or hives), seizures, a fast or irregular heartbeat, high blood pressure, difficulty urinating, fever with increased panting, muscle stiffness or muscle weakness. Other less serious side effects may occur. Continue giving Clomicalm and talk to your veterinarian if your pet has drowsiness or dizziness, dry mouth and eyes, constipation, panting, mild agitation, weakness or headache, nausea or loss of weight or appetite. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Clomicalm?

Give the missed dose as soon as you remember. However, if is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.

What happens if I overdose my pet on Clomicalm?

If an overdose of Clomicalm is suspected, contact your veterinarian or emergency veterinary clinic immediately.

What should I avoid while giving Clomicalm to my pet?

Clomicalm may cause dizziness or drowsiness. Do not stop giving Clomicalm suddenly. This could cause symptoms such as nausea and malaise.

What should I avoid while giving Clomicalm to my pet?

Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines including herbal products.

What other drugs will affect Clomicalm:

Do not give this medication if your pet has taken or used a monoamine oxidase inhibitor (MAOI) such as selegiline, Mitaban Dip or Preventic Collar within the last 14 days. Clomicalm may increase the effects of other drugs that may cause drowsiness, including other antidepressants, antihistamines, sedatives, pain relievers, anxiety medications, and muscle relaxants. Drugs other than those listed may also interact with Clomicalm.

How to Use

Clomicalm Tablets Directions:

  • Clomicalm Tablets is a prescription medication used in dogs to treat separation anxiety.
  • Clomicalm Tablets is not for cats.
  • Clomicalm Tablets is classified as a tricyclic antidepressant. Clomicalm Tablets affect chemicals in the brain that may become unbalanced leading to behavioral problems in dogs.
  • Clomicalm Tablets can be administered as a single daily dose or twice daily based on pets response. To minimize side effects, you may want to initiate treatment in divided doses.
Tip:

Clomicalm Tablets may not help alleviate symptoms right away. It may take a number of days before symptoms begin to lessen.

Clomicalm Dosage for Dogs:

Dogs:
WeightDosage
11-22 lbs (Blue Box)Give one 20 mg tablet once daily with food. Allow pet to have plenty of water to drink
44.1-88 lbs (Green Box)Give one 80 mg tablet once daily with food. Allow pet to have plenty of water to drink
88.1 - 176 lbs (Green Box)Give two 80 mg tablets once daily with food. Allow pet to have plenty of water to drink
Clomicalm Dosage for Cats:
Cats
Do not use!
Clomicalm Dosage for Horses:
Horses
Do not use!
Storage:

Store Clomicalm Tablets at room temperature away from moisture and heat.

Ingredients

Clomicalm Ingredients:

Clomicalm Blue for Dogs 11-22 lbs
Active IngredientsAmount
Clomipramine Hydrochloride20 mg
Clomicalm Purple for Dogs 22.1-44 lbs
Active IngredientsAmount
Clomipramine Hydrochloride40 mg
Clomicalm Green for Dogs 44.1- 176 lbs
Active IngredientsAmount
Clomipramine Hydrochloride80 mg
Customer Reviews
Clomicalm is rated 4.4 out of 5 by 47.
Rated 2 out of 5 by from No effect Although it was well tolerated by my four year old greyhound, it had no effect on her behavior. I was seeking a medication to ease her separation anxiety and thunder phobia. After about 12 weeks of use I saw little to no changes.
Date published: 2017-08-24
Rated 5 out of 5 by from wonderful! Thank god my vet thought this would be an appropriate medication for my dog! Very friendly boy but he has always been over protective of me and EXTREMELY anxious (he tried to go through my window once because I left for work **Scary Stuff!!**), our first vet wasn't much help so we switched to our new vet (we love him!), and we went to three different trainers all who use different training styles, and consulted with a behavior specialist at University of Pennsylvania to try and fix some issues. All of which didn't end in a complete fail but we didn't get the results that were needed. After all the craziness our vet suggested clomicalm. This medication has worked wonders! I will say that if I don't exercise him as much as needed he'll be a little more on edge because of excess energy but other than that it has made all the difference in the world for my dog!
Date published: 2017-08-18
Rated 5 out of 5 by from Works for my pup My chihuahua was on me like a tick on a dog, licking, sitting on me, with a little pitiful cry, pacing while riding in car, so I could get her to focus on anything else. Clomicalm has helped all of those behaviors, she is relaxed in the car and will nap now, her incessant fixation on me is gone and I have a loving, sweet pup now. I was able with PetMeds help use 20 mg pills broken into 4 doses to lower my monthly price! Much more affordable on senior income.
Date published: 2017-08-15
Rated 5 out of 5 by from Lifesaver! Clomicalm was a lifesaver for us. We had a senior Golden Retriever that suffered from anxiety whenever she sensed a thunderstorm brewing. Later in her life, she had ear surgery. Her hearing was gone but she still heard the humming/vibration from the A/C units and knew when it was thundering. Clomicalm worked to soothe her anxiety without any negative side effects.
Date published: 2017-06-01
Rated 3 out of 5 by from Not strong enough for severe cases I'm still trying to figure out how I feel about this med - it has definitely helped my dog with severe separation anxiety, but not enough to stop her behaviors completely. I have an issue with a noisy neighbor, on top of my dog's anxiety issues - not sure if this is what's triggering her, but she's been on this medication for almost 2 months, and I still occasionally come home to find chewed up laundry baskets, boxes, papers, etc. Don't get me wrong - it's better than coming home to chewed up carpet and baseboards (which is what I was dealing with before) but I'm just not convinced this is strong enough for my little girl. Also, I'm still trying to figure out the timing of dosages - it takes about an hour to kick in, and it seems like the effects of the meds last for 12 hours and then wear off? I've noticed if I give her the night dose around 5pm (she's on 40mg per dose), she will wake up at 5am freaking out and pawing at my head, and shaking! It's really strange. I don't know if that's when it wears off, or something is triggering her to wake up with anxiety at this time, but it's weird. Also!! For us, things got way WORSE before they got better. I first put her on this med because she chewed up a bit of carpet by the door...1-2 weeks after starting the med, the little spot that was chewed turned into THE WHOLE ROOM DESTROYED. I ended up putting her in doggy day care until she adjusted to the meds, because I couldn't keep coming home to damage to my apartment!! All in all, this may be good for dogs with mild to moderate anxiety issues, but for severe cases, it might not be strong enough. Considering switching to doggie Prozac :/
Date published: 2017-04-13
Rated 5 out of 5 by from Great results! My dog can't survive with this medication. He suffers from severe separation anxiety and this is the only medication that works for noon.
Date published: 2017-03-13
Rated 5 out of 5 by from Amazing! I have a 2 year old rescued boxer/lab and ever since she was an 3 month old puppy she has had horrible separation anxiety. She would bark until no end, she has destroyed sofas, our wooden coffee table, shoes, you name it she's destroyed it. No matter how much conditioning training sessions I've done nothing has ever helped. The only way to keep her out of trouble was crate training which worked, but I felt horrible leaving her in a crate all day. A month ago my vet recommended this medication and I fully understood between him and these reviews that it can take weeks to months for it to take effect and I was prepared to give her at least 2 months in waiting time. A week into the medication and I was able to leave her out of her crate without a single worry! It's been a month she's been on this medication and I honestly cannot believe how my baby has done a complete 180! She is even starting to get over her fear of strangers and is slowly starting to open up to other dogs. I've already recommended this to many of my friends who have pups with separation anxiety!
Date published: 2017-03-05
Rated 4 out of 5 by from Finally, something that workS. At first I didn't like what it did to my 16 year old baby. He was very constipated & so out of it. When I took him for his walks, it was like he was lost & would just stand frozen in place. So, I I cut his dose in half & now we're both happy. I can now leave the house & he doesn't bark. He's relaxed & I have less stress worrying about getting thrown out of my apartment. He's a senior with limited sight & hearing. So, his fear was being alone. We're both happy campers.
Date published: 2017-02-03
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Q&A

I have a pit mix and he is very aggressive to others, even jealous towards of my son. I need something to calm my dog down. I have raise for 7 weeks old n don't wanna put down.

Asked by: Redd
Theres no need to put your dog down. If you cant handle the dog, you need to bring him to a RESCUE. Thats irresponsible of you to kill you dog because of behaviour.
Answered by: Bard brd
Date published: 2017-12-14

What dosage do I give a 4.6lb Miniature Pinscher?

Asked by: Chris
Your veterinarian decides the dose for your dog. The usual dose for a dog that size can be 5mg per day. Consult with your veterinarian.
Answered by: Ben B
Date published: 2017-03-13

how long is it safe for a dog to be on this medication?

Asked by: Puddles
This drug lasts in your dogs body for about a day. Some pets can stay on the drug long-term. I would recommend using it for however long your veterinarian has prescribed it.
Answered by: Ben B
Date published: 2017-02-21

My dog's prescription is for 50 mg.  Is that available?

Asked by: Linda
No, we only have 20 mg and 80 mg available. You could take two and a half of the 20 mg tablets to equal 50 mg.
Answered by: Christine
Date published: 2016-10-04

Is it ok to mix clomicalm with calming chews?

Asked by: Megan4245
Yes, it is okay to give your pet both Clomicalm and calming chews, if needed.
Answered by: Christine
Date published: 2016-10-04

Is it addictive

Asked by: Jmorain
This medication is not addictive. However, if this medication is stopped, it should be tapered off slowly as directed by your veterinarian. Your pet can build up a tolerance to this medication, and stopping immediately may cause withdrawals and adverse effects.
Answered by: Christine
Date published: 2016-10-03

Hi I have a pug/lab mix we adopted him from a shelter when he was 6 months. He has awful separation aniexty,he barks constantly if we are not their. We have been putting him in a crate sence we got him a year ago and he still isn't used to it. Please help

Asked by: Maddie21
Clomicalm (clomipramine) is used to treat separation anxiety in dogs in connection with behavior modification and training. Clomicalm requires a prescription from your veterinarian.
Answered by: Christine
Date published: 2017-05-31

is clomicalm suitable for older dogs

Asked by: mack
It may be a suitable medication for an older dog with anxiety issues. Its really up to your veterinarian to decide if its a good choice for your individual pet based on over all health , symptoms, etc.
Answered by: Linda petmeds pharmacist
Date published: 2015-07-14
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