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Adaptil For Dogs

Starts $33.03 $22.49 
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Spray 60 ml
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Plug In with 48 ml Bottle
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48 ml Refill Bottle
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Product Info

What is Adaptil for Dogs?

Adaptil For Dogs is a plug-in diffuser that releases a calming pheromone. Just plug it into the room where your dog displays signs of stress, and get 24-hour control. Adaptil also comes in a spray that can be used on your dog's bedding.


Dogs and Puppies


  • Reduces or stops stress-related behavior, including barking, whimpering and whining, chewing, urination, and defecation
  • Helps comfort dogs in stressful situations such as being alone in the house, having visitors, adjusting to a new pet or family member, moving, and visits to the veterinarian
  • One diffuser bottle lasts for approximately 30 days and covers up to 650 square feet
  • Odorless and nontoxic (does not affect humans)
  • Also comes in a spray
  • Refills are available

How does Adaptil For Dogs work?

When you plug Adaptil into an electrical socket, it emits a scent that mimics naturally reassuring pheromones. It includes Adaptil (Dog Appeasing Pheromone), a proprietary formula that mimics the appeasing pheromones secreted by female dogs when nursing that sends a signal of comfort and safety to her puppies. When your dog senses the pheromone, he or she feels secure and comfortable, reducing anxious reactions and the urge to act out destructively.


Read all instructions before using. To reduce the risk of injury, close supervision is necessary when the product is used near children. Do not put fingers or hands into the diffuser. Adult assembly is required. The surfaces of the diffuser reach high temperatures to create evaporation of active ingredients. These surfaces should not be touched when plugged in. Don't use this product with any other type of plug-in device, or place it underneath or behind furniture. When plugged in, do not touch with metal objects or wet hands. Harmful if swallowed. Call your physician immediately.

How to Use

Adaptil for Dogs Directions:

  • For Adaptil For Dogs Plug-in Diffuser: Remove the cap from the bottle. Screw the diffuser onto the bottle and tighten. Plug the diffuser unit into an electrical outlet in the room your dog spends the most time in. One bottle of the Plug-In Diffuser lasts approximately four weeks and covers an area of approximately 500-650 sq ft.
  • Replace the bottle after 4 weeks. Use for 90 days for best results
  • Diffuser Maintenance: Oils may collect on the diffuser over time. To clean, remove the diffuser from the outlet and wipe it with a clean, dry cloth. If the diffuser is removed from the outlet, separate the refill from the diffuser and store it at room temperature in the upright position.
  • For Adaptil For Dogs Spray: Spray the area 15 minutes before introducing your dog. Use 8-10 sprays every 2 hours to help keep your dog calm and relaxed.

When using Adaptil Spray, do not spray directly onto your dog.

Adaptil for Dogs Plug In Diffuser Usage:
All weights
Plug Adaptil For Dogs diffuser unit into an electrical socket in the room most used by the dog. One bottle lasts approximately four weeks and covers an area of approximately 500 to 650 sq ft.
Adaptil for Dogs Spray Usage:
All weights
Spray on the bed or bandana, in the car, or crate 15 minutes before exposing your dog to the treatment area. Use 8-10 sprays every 2 hours. Do not spray directly on your dog.
Do not use!
Do not use!

All Adaptil products should be stored at room temperature. Always store diffuser bottles in the upright position.


Adaptil for Dogs Ingredients:

Adaptil for Dogs (48 ml Plug in Refill Bottle)
Analogue of Dog Appeasing Pheromones
Isoparaffinic Hydrocarbon (a petroleum distillate)
100 g
Adaptil for Dogs Plug in (with 48 ml Bottle)
Analogue of Dog Appeasing Pheromones
Isoparaffinic Hydrocarbon (a petroleum distillate)
100 g
Adaptil for Dogs (60 ml Spray Bottle)
Analogue of Dog Appeasing Pheromones
60 ml
Customer Reviews
Comfort Zone For Dogs is rated 2.9 out of 5 by 72.
Rated 5 out of 5 by from So far so good. We have a very energetic 1yr old pitbull who was just too much energy for the smaller dogs so we got this in hopes it'd chill him out, and it did!! He's no cat chill by any means but he's calmed down a lot and not all over the place. Noticeable change abs will continue to buy. Makes the older dogs more relaxed too, it's great!!
Date published: 2017-03-14
Rated 5 out of 5 by from Love it My Chihuahua doesn't like my brother in law or sister so when they come to visit he barks non stop and since buying it he has done a lot better.
Date published: 2016-11-15
Rated 1 out of 5 by from Disappointing I tried this product at the advise of my vet. I am looking for something to treat anxiety besides pills. I have seen no change in my dog since I started using it. The good news is 1800petmeds has refunded the full price of the product.
Date published: 2016-07-17
Date published: 2015-04-30
Rated 1 out of 5 by from Nope I bought the spray. It doesn't seem to do anything for my poor dog during thunderstorms. I'll keep trying ...
Date published: 2014-08-20
Rated 5 out of 5 by from Highly recommended--well worth the $$ I purchased this product after we got our 2ND German Sheperd puppy. The first puppy was/is really wound tight and the second puppy was a whiner. Not bad dogs just not "peaceful". The first night they slept through the night--whining was reduced to minimal and the wound tight puppy settled into a calmer presence. I recommend this product to anyone who thinks they need to help their dog be a bit calmer. We don't notice the diffuser--can't detect any odor--but the dogs have calmed considerably!! When we leave them home to run errands we are coming back to much quieter less stressed puppies.
Date published: 2014-08-07
Rated 3 out of 5 by from Dachshund Mix/Chihuahua Can't really tell yet. Only in use for 1 week.
Date published: 2014-07-31
Rated 5 out of 5 by from Transformation realized Yes we recommend this product as our 9month old Golden Retriever was mauling his food as well as always hyper and just couldn't settle down and as he grew it got know better until we found this product which seems to do the trick. He actually now leaves some food in his bowl and sleeps much better through the day and night. works continually 24/7 and only wish it was more reasonably priced for seniors of a limited lower income but we will continue using till we ane without it. Thank you Comfort Zone
Date published: 2014-07-08
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My dog is calm when only one person is in the house. With 2 or more, he acts out by climbing on me or pushing between me & other people especially if I touch anyone. Will this product help calm him down and will I need one in every room he's alooked in?

Asked by: Theresa
Comfort Zone with Adaptil For Dogs is a plug-in diffuser that releases a calming pheromone. Just plug it into the room where your dog displays signs of stress, and get 24-hour control. Comfort Zone also comes in a spray that can be used on your dog's bedding. This should help calm him down. You would need one for every room he's in, since it is plugged in and releases the calming pheromones in that area.
Answered by: Christine
Date published: 2016-10-05

Can I keep the same plug in and just put new refill bottles in as needed?

How long do the PLUG INS last? Can I just keep putting refill bottles on same plug in as needed?
Asked by: dog lover
Thank you for your question. Yes, you can use the same plug in and just use different refills. Each refill lasts 30 days.
Answered by: Maureen PetMeds Pro
Date published: 2014-08-30

Does this affect cats?

I have a dog and three cats. Our dog is the one stressed out and anxious. Will this have an adverse reaction on our cats?
Asked by: AJ
No, the kitty will not be affected
Answered by: Linda petmeds pharmacist
Date published: 2014-07-30

Multiple dogs only 1 has anxiety.

We have 3 dogs. Only one of them is experienceing anxiety. The other 2 have polar opposite personalities though. Our oldest is extremely laid back and lazy througout the day. The youngest is hyper at times, but nothing out of the ordinary. It is out middle dog that has anxiety. She chews her paws almost constantly. Will this product have any adverse effect on our older dog since he is already pretty mellow? I don't want him being any calmer than he his lol.
Asked by: stan26351
Hi there, great question, no worries, your dog that does not have any issues should not experience any reaction with this product.
Answered by: James PetMeds Pro
Date published: 2014-07-24

my DAP difusser is not lasting 30 days anymore, seems to be running out after 24- 25 days.

I have using the DAP difusser for about one year,the refill are only lasting 24-25 days. Why ?
Asked by: Linda
you need to replace the difusser ever 6mo. not just the refill. this will make the refill last 30 days
Answered by: deb
Date published: 2013-10-22

i have two female dogs a mother and daughter will this cause them to have not get along when using it around both

I know that it release female pheromones like when they are pregnant and have babies and I know that females get a little aggressive when in heat or have babies will this cause my two to not get along well when used around both at the same time?
Asked by: CrazyLady
Thank you for your question. This product is designed to keep your furry pals calm and relieve stress. We do suggest you speak with your vet prior to using this, as there are no listed side effects but we want to ensure your babies are safe.
Answered by: Maureen PetMeds Pro
Date published: 2013-10-22

Not sure that this is working, may end up returning

My dog is elderly and has developed separation anxiety over the past 6 months. She is destructive and urinates on the carpet and area rugs anytime I leave the house. I was hoping that this product would help alleviate these behaviors, but so far it has not. Now, I've only had the product a week, but I am leaving it plugged in 24/7. My home is very small. I only bought 1 diffuser because my dog only has access to the first floor of the house while I am gone, and the square footage on the first floor is not bigger than what is recommended on the box. So, how long should I give this before making the decision whether to return it? The box also says allow 3-4 weeks to start working, but then further goes on to say to use for 90 days for full effectiveness. I find this very confusing, especially considering that other customers are saying that they only plug in the diffuser as needed for stressful situations with their dog. Please provide some guidance on this. Thank you.
Asked by: blue
It doesn't effect.....he still destroys things and urinates in his crate.
Answered by: Satchmo
Date published: 2013-10-22

Can this product harm birds?

I have a pet cockatiel and do not want to use anything that will harm my bird.
Asked by: Tina
Comfort Zone with DAP uses a parrafin wax base to spread a species-specific pheromone to reduce some unwanted behaviors. The ambient effect is similar to an unscented candle. Birds are very sensitive due to their respiratory system, and if you do not use non-scented candles in the home, then we would not recommend using the diffuser. If there are no concerns using candles near your bird, the diffuser should be placed on the opposite wall of the birds at least 9 ft away or in another room.
Answered by: Chris H, PetMedPro
Date published: 2013-10-22
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