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Activyl

Starts $85.48 $59.98 
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info

What is Activyl?

Activyl is a monthly spot-on flea treatment that works like no other flea product on the market. Activyl works by using a method called bioactivation, a method in which the active ingredient, indoxacarb is fully activated by using the flea's own enzymes. Activyl can be used for both dogs and cats. It kills not only adult fleas but also flea eggs and larvae, thereby breaking the flea lifecycle.

For dogs only, use Activyl Tick Plus to protect against ticks.

For:

Cats/Kittens and Dogs/Puppies (8+ weeks of age)

Benefits:

  • New technology for flea control
  • Kills fleas, flea eggs and larvae
  • Breaks the flea lifecycle
  • Quick-drying and fragrance-free
  • Waterproof even after bathing

How does Activyl work?

Activyl works to break the flea lifecycle by killing not only adult fleas, but also flea eggs and larvae, which reduces the chances of your pet becoming reinfested. Activyl is spread through your pet's skin and coat. When a flea lands on your pet, it takes up the active ingredient of Activyl and causes the enzymes in the flea to change. Activyl then reaches its full active form and the flea becomes paralyzed and unable to feed. This process is called bioactivation - the newest technology in flea control. In addition, Activyl is waterproof, quick-drying, and fragrance free.

Cautions:

Do not use Activyl for dogs on cats, or allow your cat to lick or groom a dog treated with Activyl. Do not use on cats or kittens under 2 lbs, or dogs or puppies under 4 lbs, and no kittens or puppies under 8 weeks of age. Certain medications may interact with pesticides. If signs of sensitivity occur, contact your veterinarian immediately.

Brand Name:

Activyl

Generic Name:

Indoxacarb

What is the most important thing I should know about Activyl?

Activyl is a monthly spot-on flea treatment that works like no other flea product on the market. Activyl works by a method called bioactivation. This method uses the flea's own enzymes to change Activyl into its fully active form. It kills not only adult fleas, but it also kills eggs and larvae too; thereby, breaking the flea's lifecycle. Activyl is a non-prescription (OTC) product.

What should I discuss with my veterinarian before giving Activyl to my pet?

Consult your vet before using on debilitated, aged, or medicated dogs. Certain medications can interact with pesticides. If signs of sensitivity occur, contact your veterinarian immediately.

How should Activyl be applied?

Use Activyl on dogs and puppies 8 weeks of age or older. It is available as 0.51 ml applicators for dogs 4.1-14 lbs, 0.77 ml applicators for dogs 14.1-22 lbs, 1.54 ml applicators for dogs 22.1-44 lbs, 3.08 ml applicators for dogs 44.1-88 lbs and 4.62 ml applicators for dogs 88.1-132 lbs. It is also available for cats 2-9 lbs in 0.51 ml applicators and cats over 9 lbs in 1.03 ml applicators. It lasts for a full 30 days. DO NOT USE ACTIVYL FOR DOGS ON CATS. For cats, use only Activyl specifically formulated for cats and kittens.

Hold the applicator in an upright position away from your face and snap the tip by bending it and folding it back on itself. Part the hair and place the applicator tip against the skin on the base of the skull. Applying Activyl at the base of the skull will help prevent your pet from licking the product. Squeeze the applicator firmly and apply the entire contents directly to the skin. Do not allow Activyl to run off and do not have contact with the treated area until it is completely dry. Reapply Activyl every 30 days.

For Larger Dogs: Start applying the contents between the shoulder blades working your way down to the tail while applying Activyl in 2-3 spots along the way. Make sure you thoroughly part the hair on each spot so the applicator touches the skin and not just the fur.

What are the potential side effects of Activyl?

Individual sensitivities while rare, may occur after using any pesticide product. In cats, accidental ingestion may cause intermittent salivation, licking of the face, shaking of the head, and squinting.

What happens if I miss giving a dose of Activyl?

Apply the missed dose as soon as you remember. However, if is almost time for the next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not apply a double dose of the medication.

What happens if I overdose my pet on Activyl?

Contact your veterinarian or veterinary emergency room.

What should I avoid while giving Activyl to my pet?

Do not use on pregnant or lactating females. Do not use on puppies or kittens under 8 weeks of age. Use the entire contents on each cat or dog and do not split one tube between pets. Weigh your dog to ensure you are applying the right dose formulated for the weight of your dog.

Causes eye irritation. Avoid contact with skin, eyes, or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet.

If swallowed: Call a physician or poison control center or a doctor for treatment advice. Drink 1 or 2 glasses of water and do not induce vomiting unless told to by poison control center. Do not give anything by mouth to an unconscious person. If in eyes: Hold eyes open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, continue rinsing. Call a physician or poison control center or a doctor for treatment advice. If on skin: Wash thoroughly with plenty of soap and water. Get medical attention if irritation persists.

What other drugs will affect Activyl?

Certain medications can interact with pesticides. Consult a veterinarian before using on medicated pets.

How to Use

Activyl Directions:

  • Hold the applicator in an upright position away from your face and snap the tip by bending it and folding it back on itself.
  • Part the hair and place the applicator tip against the skin on the base of the skull. Applying Activyl at the base of the skull will help prevent your pet from licking the product.
  • Squeeze the applicator firmly and apply the entire contents directly to the skin.
  • Do not allow Activyl to run off and do not have contact with the treated area until it is completely dry.
  • Reapply Activyl every 30 days.
  • For Larger Dogs: Start applying the contents between the shoulder blades working your way down to the tail while applying Activyl in 2-3 spots along the way. Make sure you thoroughly part the hair on each spot so the applicator touches the skin and not just the fur.
Tip:

Wait until the application site is fully dry (usually 24 hours) before bathing your pet. Also, allow 24 hours before letting your dog go swimming or allowing your cat to get wet.

Dosage:
Dogs/Puppies:
(over 8 weeks of age)
Weight
Dosage
4.1-14 lbs
Apply contents of 1 applicator once a month (0.51 ml/0.02 fl oz)
14.1- 22 lbs
Apply contents of 1 applicator once a month (0.77 ml/0.03 fl oz)
22.1-44 lbs
Apply contents of 1 applicator once a month (1.54 ml/0.05 fl oz)
44.1-88 lbs
Apply contents of 1 applicator once a month (3.08 ml/0.1 fl oz)
88.1-132 lbs
Apply contents of 1 applicator once a month (4.62 ml/0.16 fl oz)
Cats & Kittens:
Weight
Dosage
2-9 lbs
Apply contents of 1 applicator once a month (0.51 ml/0.02 fl oz)
Over 9 lbs
Apply contents of 1 applicator once a month (1.03 ml/0.03 fl oz)
Horses:
Do not use!
Storage:

Do not remove tube from pack until ready to use. Store in a cool (below 77°F) dry place inaccessible to children and pets. Do not refrigerate and protect from direct sunlight.

Ingredients

Activyl Ingredients:

Activyl for Dogs Over 4.1-14 lbs:
Active ingredients (per 0.51 ml/0.02 fl oz applicator)
Amount
Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate
19.53%
Other Ingredients
80.47%
Activyl for Dogs Over 14.1-22 lbs:
Active ingredients (per 0.77 ml/0.03 fl oz applicator)
Amount
Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate
19.53%
Other Ingredients
80.47%
Activyl for Dogs Over 22.1-44 lbs:
Active ingredients (per 1.54 ml/0.05 fl oz applicator)
Amount
Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate
19.53%
Other Ingredients
80.47%
Activyl for Dogs Over 44.1-88 lbs:
Active ingredients (per 3.08 ml/0.1 fl oz applicator)
Amount
Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate
19.53%
Other Ingredients
80.47%
Activyl for Dogs Over 88.1-132 lbs:
Active ingredients (per 4.62 ml/0.16 fl oz applicator)
Amount
Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate
19.53%
Other Ingredients
80.47%
Activyl for Cats 2-9 lbs:
Active Ingredients (per 0.51 ml/0.02 fl oz applicator)
Amount
Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate
19.53%
Other Ingredients
80.47%
Activyl for Cats Over 9 lbs:
Active Ingredients (per 1.03 ml/0.03 fl oz applicator)
Amount
Indoxacarb: (S)-methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-trifluoromethoxy)phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate
19.53%
Other Ingredients
80.47%
Customer Reviews
Activyl is rated 4.3 out of 5 by 58.
Rated 5 out of 5 by from finally I am beating the fleas Had tried several products off the shelf and the fleas laffed at me Even combed them out of the place I had applied the flea product This stuff works & my cats & dogs finally have relief from all the little biting creatures . Amen
Date published: 2017-12-08
Rated 5 out of 5 by from when everything else fails Activyl for Cats: I have 2 elderly cats and I've used Frontline for several years, then after 3 years it stopped working on the fleas, so I switched to Advantage II, worked for 2 years, then it to stopped working (fleas became immune) Now I've switched to Activyl and it started working within a few hours and both cats have been flea free for the whole month. I will continue to use this for as long as it works. The fleas this year have been especially nasty. I hope this stuff will continue to work. BTW, it has a lot less side affects then the other products.
Date published: 2017-11-27
Rated 5 out of 5 by from Wonderful Product My house cat had gotten fleas and we had tried other spot treatments that didn't seem to be working. We had used flea bombs, sprayed all the baseboards, flea wash, and were vacuuming 3 times a day. We put Activyl on our cat 2 months ago and within a week, the fleas were gone from our house. I'm so thankful I found this product!
Date published: 2017-11-25
Rated 5 out of 5 by from activyl for cats I have three cats, Mojo, Ziggy, and Carrot Top. Have been using Frontline Plus for the Ticks but it stops working after about two weeks if it does any good at all. I tried advantage it works three weeks tops. But Activyl seems to work for the full month. So far it has worked the best, and no Ticks.
Date published: 2017-08-29
Rated 4 out of 5 by from Worked! Great Have 3 dogs and cats and fleas got out of control even tho we had treated with Advantage 2, I went back to Activyl and sure enough--my dogs finally got relief and I am very satisfied with this product.
Date published: 2017-08-27
Rated 4 out of 5 by from Seems to work well The cats haven't gotten fleas since I started using this. The fleas seems to be getting resistant to other brands, so I hope this one keeps working.
Date published: 2017-08-19
Rated 1 out of 5 by from This does not protect against both ticks and fleas I am sorry to have to return this, I need the Activyl that protects against both ticks and fleas, per my vet. I cannot exchange since you no longer carry the TickPlus version of Activyl, even though you are advertising that you do.
Date published: 2017-08-17
Rated 5 out of 5 by from Happy Cats I bought this product to try out because the stuff at the vet was too pricey and it didn't work for fleas. I am so glad I got Activyl because my cats have stopped scratching and all the sores and lumps and bumps from scratching has cleared up. I wish I knew about this a long time ago. Thanks petmeds :)
Date published: 2017-08-16
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Q&A

How long after applying Activyl can i bath my pets??

Asked by: TARB4
Hello, thanks for your question. You should wait until Activyl is completely dry, which usually takes 24 hours, before bathing your pet.
Answered by: Adriane
Date published: 2017-11-27

will this kill any fleas already on my kitten?

Asked by: isela
Activyl works to break the flea's lifecycle by killing not only adult fleas, but also flea eggs and larvae, which reduces the chances of your pet becoming reinfested. Activyl is spread through your pet's skin and coat. When a flea lands on your pet, it takes up the active ingredient of Activyl and causes the enzymes in the flea to change. Activyl then reaches its full active form and the flea becomes paralyzed and unable to feed. This process is called bioactivation .
Answered by: Cherley Petmeds Pro
Date published: 2017-09-05

what happens if a cat gts a dose of actyvil for dogs? what to do when this happens?

Asked by: kitty
Thank you for your question. While the active ingredients and topical liquid look the same. There may be a difference in the inactive ingredients and for that reason we ask that you follow manufacturers directions. Do not use Activyl for dogs on cats due to inappropriate dosing. In the event of an overdose, contact your veterinarian or veterinary emergency room.
Answered by: leanniejo
Date published: 2017-08-23

Is there any indication as to when this product will be back in stock? "5/11/17" had been and gone...

Asked by: JenPA
May I suggest that you liase with your stock control dept? I received a notification email that this product is now back in stock shortly before receiving your answer!
Answered by: JenPA
Date published: 2017-05-24

What's happening with this product? There are NO options available. I've called and emailed multiple times. Give your customers answers with an explanation.

Asked by: Rykitten
This product has an expected back to stock date of 5/11/17
Answered by: Amy Petmed Pro
Date published: 2017-05-08

How long is activyl good for if stored properly and has not be opened

Asked by: Framp
Activyl does not expire..
Answered by: Amy Petmed Pro
Date published: 2017-08-23

When with this product be back in stock? I need the option for cats under 9, cats over 9, and dogs over 89. Thanks. 

Asked by: Jess1234
7/1/17
Answered by: Amy Petmed Pro
Date published: 2017-04-20

Do you ever have the largest breed dog in stock?

Asked by: Brynns
We are expecting a shipment of this product approximately 4/24/17
Answered by: Amy Petmed Pro
Date published: 2017-03-14
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