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Product Info

What is Cholodin?

Cholodin is a chewable dietary supplement that helps remedy various conditions in senior dogs. It has been recommended by veterinarians for age-related problems, including fatigue, poor coat, constipation, inappropriate urination, poor appetite, and poor mental performance.




  • Fights many more ailments than most supplements
  • Prevents inflammation in the liver and retains optimal liver function
  • Restores youthful health for senior dogs
  • Contains vitamin B12 (cyanocobalamin), which is important for your dog's nervous system
  • It's an easily-fed chewable tablet

How does Cholodin work?

Cholodin contains choline (a nutrient in the vitamin B family), amino acids, vitamins, and minerals to help restore a youthful vigor in your pet. The tablets should be given on a daily basis, and can be fed by hand or crumbled and mixed with food.


If your dog shows increased neurological activity (hyperactivity, social agitation, muscular twitching), contact your veterinarian. Infrequently, pets on a choline loading regimen will show signs of increased neurological activity such as hyperactivity, social agitation, muscular twitching, etc. If these responses are noticed, cessation of tablet administration will quickly result in disappearance of these irregularities. After a period of 3 or 4 days, your pet may resume the same dosage, usually with no adverse reaction. Keep out of reach of children and pets.

How to Use

Cholodin Directions:

  • Cholodin is a chewable dietary supplement containing Choline (a nutrient in the B Vitamin family), amino acids, vitamins, and minerals.
  • Cholodin is formulated for use in geriatric pets.
  • Cholodin is for dogs only. Do not give to cats.
  • The chewable tablets can be fed directly to the pet by hand or crumbled and mixed with food.

In rare instances a pet may become hyperactive. Discontinue giving the product for 3 or 4 days and then resume the same dosage.

Small Dogs (25 lbs or less)
Give ½ chewable tablet daily
Medium Dogs (25-50 lbs)
Give 1 chewable tablet daily
Large Dogs (over 50 lbs)
Give 2 chewable tablets daily
Do not use!
Do not use!

Should be stored at room temperature.


Cholodin Ingredients:

Active Ingredients (per chewable tablet): Lactose, Lecithin, Powdered Cellulose, Silicon Dioxide, Choline Chloride, DL-Methionine, Inositol, Animal Liver Meal (Pork), Dried Beans, Magnesium Stearate, Torula Dried Yeast, DL-Alpha Tocopheryl Acetate, Zinc Oxide, Thiamine Mononitrate, Niacinamide, Riboflavin, Calcium Pantothenate, Pyridoxine HCL, Sodium Selenite, Vitamin B12 supplement.

Guaranteed analysis per tablet: all values are in minimum quantities

Amino Acids:
55 mg
7.2 mg
0.02 mg
Vitamins and Others:
Vitamin E
5 IU
1.5 mg
1.5 mg
Pantothenic Acid
1 mg
5 mg
1 mg
Vitamin B12
2.0 mcg
40 mg
40 mg

*Not recognized as an essential nutrient by the AAFCO Dog Food Nutrient Profile

Customer Reviews
Cholodin is rated 4.6 out of 5 by 22.
Rated 5 out of 5 by from Life saving product. Wish I could give this 10 stars. I have an 18 1/2 year old pekingese (I'm beyond grateful) and as i have no kids he really is like my child! His neurologist recommended these as he has begun to display clear cognitive issues. The most prominent being what is called "Sundowners Syndrome" Same as with elderly humans with Alzheimer's or dementia -as the sun sets, he becomes extremely agitated. Barks, paces, pants, will not settle for hours until he's worn himself completely out. It was painful and deeply upsetting to witness this night after night. We tried melatonin (helps some) but he's not allowed sedatives due to other health issues. I WISH his doc had recommended this much sooner, but better late than never. While he still shows some agitation at night, it is maybe 90% improved in such a short time. I'd say I saw an improvement by day 2 which is just mind blowing to me. I'm eternally grateful to see such a marked improvement in my senior baby and would highly recommend it to any pets who are beginning to have cognitive issues. **update** I had copied my original review from Amazon to share it here. Since the initial review, after several weeks he begun to act agitated again, this time even during the day. My instinct was to increase his dose. I'm SO glad I did not. I researched it and sure enough, the manufacturer says if this happens to stop the supplement for 3-4 days, then restart it, potentially at a lower dose. I did just this and thank heavens my pup seems good again! Did I mention how great this stuff is? I want to shout it from the rooftops!!
Date published: 2016-08-09
Rated 5 out of 5 by from Definitely worth trying (Copied from Amazon. Original review 2009 and additional information 2116) I purchased this product in early January in the hopes of helping my very senior dachshund with her canine equivalent to Alzheimer's. In all fairness, this supplement does work and I saw definite response within about 48 hours. However, I ended up euthanizing her after she had only been on it for two weeks (unrelated problem) so my experience with it is somewhat limited. Where I did see almost immediate improvement was in her alertness. At nearly 17, nothing was going to reverse her problems completely, but that symptom did show quite dramatic improvement almost overnight. Within the two weeks that she was on the supplement, I saw improvements in panic attacks and awareness of her surroundings. Her physical symptoms improved, too, though in all fairness, the supplement might have done more good there if she had not been suffering from the results of a spinal stroke she had had two and a half years ago. I didn't see a lot of incontinence improvements, but again, her physical issues may have been the culprit there. What I didn't see a response was in the sleep/wake patterns and the vocalization that generally accompanies those problems. Again, though, she was only on the supplement for two weeks, so that might take more time. All in all, I'd say I saw a moderate positive response to most of the symptoms this supplement is meant to address. Again, nothing was going to reverse 17 years of aging, but if you have a dog who is beginning to show (or as in my dog's case, is well on the way) the "Old Dog Syndrome", this is definitely something to try. Also, one thing to keep in mind is that a 20 lb dog is going to generally get 1/2 a pill a day. You might want to keep that in mind if you're ordering a bottle to "try." Fast forward 7 years from the 2009 review. Since my review, my husband and I began fostering nothing but senior dogs, and this product has become a staple on my "dog shelf." I have now used it on at least a half dozen seniors, and I've seen marked improvement in each dog. Keep in mind that each dog will show improvement to a different degree on different things. The two areas I've seen the most consistent improvement on is in eating and the neurological areas...circling, confusion, lost in corners. I've also experienced a couple of the negative side effects the manufacturer talks about, but after taking them off the supplement for a few days and then returning them to it, the side effect disappears (usually some form of vocalization or mild anxiety). Cholodin is my default go to when I start seeing difficulty in my seniors. In a couple of cases, I've used it as a dog has begun to go blind, and this has helped them through the initial trauma of losing their sight; something that can be very helpful for a lot of dogs. it's also my first go to when I see some of the beginnings of senior dog dementia. As I said in my 2009 review, this isn't a miracle drug. Some animals benefit from it more than others (I've had one that benefited, but still needed more help from a prescription drug), and all of them to varying degrees. If you have a dog under 25 lbs, you have 1/2 a tablet per day, and that 50 tablet bottle is well worth the price to see if your dog will improve. And generally I begin to see improvement by the third day; and by the third week, I know I've gotten about as much as I'm going to get from it, which is hugely helpful. I'm changing this from 4 to 5 stars, and I highly recommend giving Cholodin a try if you have an older dog who is beginning to have difficulties.
Date published: 2016-01-18
Rated 5 out of 5 by from Very effective My small rat terrier is 16 years old. She would often walk around the house as if she was lost or confused & then stop & stare off into space. Sometimes she would just squat & potty on the floor, not even asking to go outside. After she took Cholodin for approximately 2 or maybe 3 months her behavior improved. She no longer seems to be confused & she doesn't stare off into space anymore. I don't know if it helped her pottying on the floor issue because I watch her closer, taking her out right away after playing & eating.
Date published: 2015-08-07
Rated 5 out of 5 by from Saved his life! 20 months ago my husband and I were confronted with the decision to put our beloved 12 yr old Cocker down. His "doggie dementia" was so bad that he trembled with anxiety and fear, got lost in corners, and had a blank stare of complete unrecognition. Our vet gave us several prescriptions to try, but nothing worked and the cost was really high. Out of desperation, I searched the internet and found Cholodin. Within 4 days the improvement was very noticeable, and a week after that he was nearly normal. We will never be without this great product. Thanks for the gift of his well being.
Date published: 2015-05-08
Rated 4 out of 5 by from Putting Our Lab Back on this I started giving our 11 year old female lab this product last year when she started having cognitive issues (not sleeping, standing in corners) and it seemed to make a big difference. My husband thought it was a waste of money so he had me stop for a few months. She got much worse off the cholodin and started having severe separation anxiety as well. I can't wait to get her back on this to PROVE to my husband it really made a huge difference. This works great for our old female lab.
Date published: 2015-01-11
Rated 1 out of 5 by from Didn't make a differnce I gave this to my elderly male min. poodle and did not make a difference, now I have a elderly female Aussie and again no difference. Why? I am giving her the dosage my Vet. wrote on the script.
Date published: 2014-01-11
Rated 5 out of 5 by from This product changed our lives I can't believe what a difference Cholodin made in or Whippet. Once a sweet loving dog she became very aggressive and nervous and had to be muzzled at all times. After only 2 weeks we noticed her becoming calmer. She has been on the supplement for several months and is no longer aggressive at all. She is now agian the sweet dog we thought we had lost forever. So glad I found and tried this product!
Date published: 2013-09-19
Rated 5 out of 5 by from This supplement has helped the doggie dementia This supplement has helped the doggie dementia for our 13 year old Brittany spaniel. Before our dog would growl at my husband like he was a stranger, and when he would go outside he would just stand there and stare like he forgot why he went outside. Now he recognizes my husband, and when he goes outside he acts like he knows where he is, and why he is there. Our dog even eats this tablet like it’s a treat, so we don’t have to hide it in his food.
Date published: 2013-01-09
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My dog is on a hip and joint health supplement containing glucosamine,chondrotin,MSM, Turmeric and 15 mg of zinc. Is Cholodin safe to use while on this current supplement as well, since both contain zinc? 

Asked by: Waldo
Hello Waldo, Cholodin is safe to use while taking his other supplement as the maximum zinc that can be fed is much higher than that. Here is a link for reference:
Answered by: Nemi Pharmacy Intern
Date published: 2017-06-15

What time of day do I give the CHOLODIN CHEWABLE TABLETS?

Asked by: Pamela
The chewable tablets can be fed directly to the pet by hand or crumbled and mixed with food. You may feed to pet whatever time of day is convenient.
Answered by: Amy Petmed Pro
Date published: 2017-02-03

Does cholodin have wheat or corn in any form? My 12 year old dog sometimes poops in the house.

Asked by: Leodog
Wheat or corn is not listed as an ingredient included in this product.
Answered by: Amy Petmed Pro
Date published: 2016-12-16

Vet just started my 13 yr old Boston on Anipryl for pacing and signs of dementia. Can I give him Cholodin along with that? My vet was not familiar with Cholodin.

Asked by: Destin
There are no contraindication between those two products.
Answered by: Carolyn Petmed Pro
Date published: 2016-12-07

Hello!  Can a dog be given turmeric cur cumin along with Cholodin?  Also, can melatonin also be given with Cholodin?  Thank you.

Asked by: papervsglue
There is no interactions with Cholodin and the other supplements.
Answered by: paulpharmacistintern
Date published: 2016-07-26

what drugs can you mix with the cholodin

can you mix theophyline and prednisone withe the cholodin .
Asked by: floyd
When you are taking any prescription medications you would need to ask your vet about any supplements you are going to use. He would know your Furry Child the best and would be able to provide the correct medical answer your looking for.
Answered by: James PetMeds Pro
Date published: 2015-03-31

expiration date

is there an expiration date for cholodin
Asked by: brian mclaughlin
Thank you for your question. Yes, this product will have an expiration date printed on the bottle.
Answered by: Maureen PetMeds Pro
Date published: 2014-11-21

safe to use with other suppliments

My 14 year old Boston Terrier has shown significant improvment with joint problems from taking a multi vitamin glucosamine suppliment. Is it safe to add this to her treatment as well?
Asked by: Lisa
Thank you for your question. Yes, this will be perfectly fine to add to your furry pal's daily intake.
Answered by: Maureen PetMeds Pro
Date published: 2014-10-04
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