Sentinel - Heartworm + Broad Spectrum Prevention Chewable Tablet for Dogs

A Spectrum of Protection - Worry Free Parasite Coverage for your Dog!
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About this product

What is Sentinel Flavor Tabs?

Sentinel Flavor Tabs are a once monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Sentinel Flavor Tabs requires a prescription from your veterinarian.

Suitable For:

Dogs and Puppies (4+ weeks of age, weighing 2+ lbs)

Benefits:

  • Sentinel Flavor Tabs come in a convenient and effective once-a-month dose, in a delicious pork liver flavored tablet
  • Dogs love the taste, making administration easy and convenient
  • Unique to Sentinel brand products, lufenuron stops flea eggs from hatching.
  • Sentinel Flavor Tabs have been shown to be safe for puppies as young as 4 weeks of age.
  • Provides broad-spectrum protection against 5 types of parasites including:
    • Heartworms: milbemycin oxime prevents heartworm disease.
    • Hookworms: milbemycin oxime treats and controls adult hookworms.
    • Roundworms: milbemycin oxime treats and controls adult roundworms.
    • Whipworms: milbemycin oxime treats and controls adult whipworms.
    • Immature Fleas: lufenuron prevents and controls flea populations

How does Sentinel Flavor Tabs work?

Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle.

Cautions:

Not for human use. Keep this and all drugs out of the reach of children. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in puppies less than four weeks of age and less than two pounds of body weight. Prior to administration of Sentinel Flavor Tabs, dogs should be tested for existing heartworm infections. Infected dogs should be treated to remove adult heartworms and microfilariae prior to initiating treatment with Sentinel Flavor Tabs. Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy have been noted in some treated dogs carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. It's also important to eliminate fleas and to not feed your pet rodents or uncooked meat or fish. To prevent re-infection, clean up stools on a daily basis. Consult your veterinarian for pregnant or lactating dogs.

Brand Name:

Sentinel Flavor Tabs (Merck)

Generic Name:

Milbemycin Oxime (mil-beh-my-sin ox-eem) and Lufenuron (lew-fen-your-on)

What is the most important information I should know about Sentinel Flavor Tabs?

Sentinel Flavor Tabs is a prescription medication FDA-approved for use in dogs. Sentinel Flavor Tabs is available as artificial beef flavored (derived from pork and soy protein) chewable tablets. This medication should be given once a month year-round.

What should I discuss with my veterinarian before giving Sentinel Flavor Tabs to my pet?

Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

How should Sentinel Flavor Tabs be given?

Give Sentinel Flavor Tabs exactly as directed by your veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Sentinel Flavor Tabs for dogs 2 to 10 pounds is 1 Flavor Tab every month (Brown Box), 11 to 25 pounds is 1 Flavor Tab every month (Green Box), 26 to 50 pounds is 1 Flavor Tab every month (Yellow Box) and 51 to 100 pounds is 1 Flavor Tab every month (White Box). For dogs over 100 pounds give the appropriate combination of tablets. To ensure adequate absorption, always administer Sentinel Flavor Tabs to dogs immediately after or in conjunction with a normal meal. Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Sentinel Flavor Tabs for 6 months or less, re-start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Sentinel Flavor Tabs in a dry place at controlled room temperature, between 59-77F (15-25 C). Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Consult your veterinarian for pregnant or lactating dogs.

What are the possible side effects of Sentinel Flavor Tabs?

The following adverse reactions have been reported in dogs after giving milbemycin oxime or lufenuron: vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, hypersalivation, and weakness. 

What happens if I miss giving a dose of Sentinel Flavor Tabs?

If a dose is missed and a 30-day interval between dosing is exceeded, administer Sentinel Flavor Tabs immediately and resume the monthly dosing schedule. If Sentinel Flavor Tabs replaces daily diethylcarbamazine (DEC) for heartworm prevention, the first dose must be given within 30 days after the last dose of DEC.

What happens if I overdose my pet on Sentinel Flavor Tabs?

Contact your veterinarian immediately.

What should I avoid while giving Sentinel Flavor Tabs to my pet?

Because humans can contract hookworms and roundworms from pets, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household.

What other drugs will affect Sentinel Flavor Tabs?

While Sentinel Flavor Tabs is safe to use in dogs at risk for MDRI-allele mutation (Australian Shepherds, Collies, Shelties, etc.), unless tested normal, caution is advised if your pet is also being given amiodarone (Cordarone), azole antifungals such as ketoconazole, carvedilol (Coreg), cyclosporine (Atopica), diltiazem (Cardizem), erythromycin (Ery-Tabs) or clarithromycin (Biaxin), quinidine, spironolactone (Aldactone), tamoxifen, and verapamil (Calan). Do not give Sentinel Flavor Tabs to your pet if already giving an alternate heartworm medication.

Storage:

Store in a dry place at controlled room temperature, between 59° and 77° F.

See more

Sentinel Flavor Tabs Directions:

  • Sentinel Flavor Tabs must be administered monthly, preferably on the same date each month. Treatment may begin at any time of year.
  • In geographic areas where mosquitoes and fleas are seasonal, the treatment schedule should begin one month prior to the expected onset and should continue until the end of “mosquito and flea season. In areas with year-round infestations, treatment should continue through the entire year without interruption.
  • Sentinel Flavor Tabs are given one a month month orally, year-round, at the recommended minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime and 4.55 mg/lb (10 mg/kg) lufenuron. Dogs over 100 lbs are provided the appropriate combination of tablets.
  • To ensure adequate absorption, always administer Sentinel Flavor Tabs to dogs immediately after or in conjunction with a normal meal. Food is essential for adequate absorption of lufenuron.
  • Sentinel Flavor Tabs are palatable and most dogs will consume the tablet when offered by the owner. As an alternative to direct dosing, the tablets can be hidden in food.
  • Watch your dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.
  • To speed control of flea infestation, products that kill adult fleas like Capstar Flea Treatment Tablets may be used temporarily with Sentinel Flavor Tabs depending on the severity of the infestation.
Tip:

It is important to treat all dogs in the household for fleas. Cats in the same household should be treated with approved products for heartworm prevention for cats.

Sentinel Flavor Tabs Dosage:

Dogs/puppies: (4+ weeks of age, weighing 2+ lbs)
Weight Dosage
2-10 lbs Give 1 Flavor Tab every month (Brown Box)
11-25 lbs Give 1 Flavor Tab every month (Green Box)
26-50 lbs Give 1 Flavor Tab every month (Yellow Box)
51-100 lbs Give 1 Flavor Tab every month (White Box)
Over 100 lbs Give combination of Flavor Tabs based on weight
 Dosage for Cats:
Cats
Do not use!
 Dosage for Horses:
Horses
Do not use!

Sentinel Flavor Tabs for Dogs Ingredients:

Sentinel Flavor Tabs Brown Box for Dogs 2-10 lbs:
Active Ingredient (per tablet) Amount
Milbemycin Oxime 2.3 mg
Lufenuron 46 mg
Sentinel Flavor Tabs Green Box for Dogs 11-25 lbs:
Active Ingredient (per tablet) Amount
Milbemycin Oxime 5.75 mg
Lufenuron 115 mg
Sentinel Flavor Tabs Yellow Box for Dogs 26-50 lbs:
Active Ingredient (per tablet) Amount
Milbemycin Oxime 11.5 mg
Lufenuron 230 mg
Sentinel Flavor Tabs White Box for Dogs 51-100 lbs:
Active Ingredient (per tablet) Amount
Milbemycin Oxime 23 mg
Lufenuron 460 mg
Product Details
plus minus

What is Sentinel Flavor Tabs?

Sentinel Flavor Tabs are a once monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Sentinel Flavor Tabs requires a prescription from your veterinarian.

Suitable For:

Dogs and Puppies (4+ weeks of age, weighing 2+ lbs)

Benefits:

  • Sentinel Flavor Tabs come in a convenient and effective once-a-month dose, in a delicious pork liver flavored tablet
  • Dogs love the taste, making administration easy and convenient
  • Unique to Sentinel brand products, lufenuron stops flea eggs from hatching.
  • Sentinel Flavor Tabs have been shown to be safe for puppies as young as 4 weeks of age.
  • Provides broad-spectrum protection against 5 types of parasites including:
    • Heartworms: milbemycin oxime prevents heartworm disease.
    • Hookworms: milbemycin oxime treats and controls adult hookworms.
    • Roundworms: milbemycin oxime treats and controls adult roundworms.
    • Whipworms: milbemycin oxime treats and controls adult whipworms.
    • Immature Fleas: lufenuron prevents and controls flea populations

How does Sentinel Flavor Tabs work?

Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle.

Cautions:

Not for human use. Keep this and all drugs out of the reach of children. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in puppies less than four weeks of age and less than two pounds of body weight. Prior to administration of Sentinel Flavor Tabs, dogs should be tested for existing heartworm infections. Infected dogs should be treated to remove adult heartworms and microfilariae prior to initiating treatment with Sentinel Flavor Tabs. Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy have been noted in some treated dogs carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. It's also important to eliminate fleas and to not feed your pet rodents or uncooked meat or fish. To prevent re-infection, clean up stools on a daily basis. Consult your veterinarian for pregnant or lactating dogs.

Brand Name:

Sentinel Flavor Tabs (Merck)

Generic Name:

Milbemycin Oxime (mil-beh-my-sin ox-eem) and Lufenuron (lew-fen-your-on)

What is the most important information I should know about Sentinel Flavor Tabs?

Sentinel Flavor Tabs is a prescription medication FDA-approved for use in dogs. Sentinel Flavor Tabs is available as artificial beef flavored (derived from pork and soy protein) chewable tablets. This medication should be given once a month year-round.

What should I discuss with my veterinarian before giving Sentinel Flavor Tabs to my pet?

Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

How should Sentinel Flavor Tabs be given?

Give Sentinel Flavor Tabs exactly as directed by your veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Sentinel Flavor Tabs for dogs 2 to 10 pounds is 1 Flavor Tab every month (Brown Box), 11 to 25 pounds is 1 Flavor Tab every month (Green Box), 26 to 50 pounds is 1 Flavor Tab every month (Yellow Box) and 51 to 100 pounds is 1 Flavor Tab every month (White Box). For dogs over 100 pounds give the appropriate combination of tablets. To ensure adequate absorption, always administer Sentinel Flavor Tabs to dogs immediately after or in conjunction with a normal meal. Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Sentinel Flavor Tabs for 6 months or less, re-start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Sentinel Flavor Tabs in a dry place at controlled room temperature, between 59-77F (15-25 C). Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Consult your veterinarian for pregnant or lactating dogs.

What are the possible side effects of Sentinel Flavor Tabs?

The following adverse reactions have been reported in dogs after giving milbemycin oxime or lufenuron: vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, hypersalivation, and weakness. 

What happens if I miss giving a dose of Sentinel Flavor Tabs?

If a dose is missed and a 30-day interval between dosing is exceeded, administer Sentinel Flavor Tabs immediately and resume the monthly dosing schedule. If Sentinel Flavor Tabs replaces daily diethylcarbamazine (DEC) for heartworm prevention, the first dose must be given within 30 days after the last dose of DEC.

What happens if I overdose my pet on Sentinel Flavor Tabs?

Contact your veterinarian immediately.

What should I avoid while giving Sentinel Flavor Tabs to my pet?

Because humans can contract hookworms and roundworms from pets, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household.

What other drugs will affect Sentinel Flavor Tabs?

While Sentinel Flavor Tabs is safe to use in dogs at risk for MDRI-allele mutation (Australian Shepherds, Collies, Shelties, etc.), unless tested normal, caution is advised if your pet is also being given amiodarone (Cordarone), azole antifungals such as ketoconazole, carvedilol (Coreg), cyclosporine (Atopica), diltiazem (Cardizem), erythromycin (Ery-Tabs) or clarithromycin (Biaxin), quinidine, spironolactone (Aldactone), tamoxifen, and verapamil (Calan). Do not give Sentinel Flavor Tabs to your pet if already giving an alternate heartworm medication.

Storage:

Store in a dry place at controlled room temperature, between 59° and 77° F.

See more
How to use
plus minus

Sentinel Flavor Tabs Directions:

  • Sentinel Flavor Tabs must be administered monthly, preferably on the same date each month. Treatment may begin at any time of year.
  • In geographic areas where mosquitoes and fleas are seasonal, the treatment schedule should begin one month prior to the expected onset and should continue until the end of “mosquito and flea season. In areas with year-round infestations, treatment should continue through the entire year without interruption.
  • Sentinel Flavor Tabs are given one a month month orally, year-round, at the recommended minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime and 4.55 mg/lb (10 mg/kg) lufenuron. Dogs over 100 lbs are provided the appropriate combination of tablets.
  • To ensure adequate absorption, always administer Sentinel Flavor Tabs to dogs immediately after or in conjunction with a normal meal. Food is essential for adequate absorption of lufenuron.
  • Sentinel Flavor Tabs are palatable and most dogs will consume the tablet when offered by the owner. As an alternative to direct dosing, the tablets can be hidden in food.
  • Watch your dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.
  • To speed control of flea infestation, products that kill adult fleas like Capstar Flea Treatment Tablets may be used temporarily with Sentinel Flavor Tabs depending on the severity of the infestation.
Tip:

It is important to treat all dogs in the household for fleas. Cats in the same household should be treated with approved products for heartworm prevention for cats.

Sentinel Flavor Tabs Dosage:

Dogs/puppies: (4+ weeks of age, weighing 2+ lbs)
Weight Dosage
2-10 lbs Give 1 Flavor Tab every month (Brown Box)
11-25 lbs Give 1 Flavor Tab every month (Green Box)
26-50 lbs Give 1 Flavor Tab every month (Yellow Box)
51-100 lbs Give 1 Flavor Tab every month (White Box)
Over 100 lbs Give combination of Flavor Tabs based on weight
 Dosage for Cats:
Cats
Do not use!
 Dosage for Horses:
Horses
Do not use!
Ingredients
plus minus

Sentinel Flavor Tabs for Dogs Ingredients:

Sentinel Flavor Tabs Brown Box for Dogs 2-10 lbs:
Active Ingredient (per tablet) Amount
Milbemycin Oxime 2.3 mg
Lufenuron 46 mg
Sentinel Flavor Tabs Green Box for Dogs 11-25 lbs:
Active Ingredient (per tablet) Amount
Milbemycin Oxime 5.75 mg
Lufenuron 115 mg
Sentinel Flavor Tabs Yellow Box for Dogs 26-50 lbs:
Active Ingredient (per tablet) Amount
Milbemycin Oxime 11.5 mg
Lufenuron 230 mg
Sentinel Flavor Tabs White Box for Dogs 51-100 lbs:
Active Ingredient (per tablet) Amount
Milbemycin Oxime 23 mg
Lufenuron 460 mg
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Hedi Dog
3 months ago
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Breed Dachshund
Tablets
They’re great but I have to crush them and mix it with her food so she can eat it.
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Helpful?
Tess and Eliza great
4 months ago
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Breed Maltepoo
My girls are on it and they are doing fine thank you.
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Sadie
6 months ago
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Breed Mixed
Great value for the money
My dog has been taking the med (willingly), and doing great!
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Daisy
7 months ago
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Breed Yorkie
Daisy has been on sentinel for almost 6 years. She has not had any fleas . I am very happy, l love doing business with pet med because I don’t have to worry about when to order. When Daisy is do . They automatically send me her packs. That’s a great peace of mind. Thank you PetMed .
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NathanTB
7 months ago
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Breed German shepherd/black lab
The standard
My dog has never had fleas nor tested positive for heartworms while on Sentinel, so it definitely gives me peace of mind. I have no intention of switching brands from this.
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DIVA
8 months ago
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Breed Shih-Poo
My Shih-Poo has never had a flea.
Casey has been using it for years and I have been giving her it for years.She is a healthy 15 yr old without any fleas. If the Diva likes it she is happy and so am I. Easy to order and they always check with my vet before shipping.
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Beverly
9 months ago
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Breed Silky
Product was shipped on time and in good condition. I crush the pill, add peanut butter, but it is still a struggle to get him to take it. Any suggestions?
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MKPres
9 months ago
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Breed Yorkie
She has been on it since birth
She is an 8 year old yorkie. My other two yorkies were on it as well.They lived to be 16 and 13. It works fine.
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