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Seresto - Activyl Tick Plus
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Activyl Tick Plus
Seresto
Kills Fleas checkmark checkmark
Repels Fleas X mark checkmark
Kills Flea eggs and Larvae checkmark checkmark
Kills Ticks checkmark checkmark
Repels Ticks X mark checkmark
Kills and/or Repels Mosquitoes X mark X mark
Prevents Heartworm X mark X mark
Other Parasites Information NA Kills biting lice plus aids in the treatment & control of sarcoptic mange on dogs.
Waterproof (shampooing once a week can reduce effectiveness) checkmark checkmark
Safe for pregnant or nursing Pets X mark Consult veterinarian before use.
How long does it take to work Reapply every 30 days. Kills fleas within 24 hours, and reinfesting fleas are killed in 2 hours. Reinfesting ticks are repelled and/or killed in 6 hours.
Taste Applied to skin Collar
Active Ingredient(s) Indoxacarb, Permethrin Flumethrin, Imidacloprid
RX Required X mark X mark
Dosage
Usage Activyl Tick Plus Usage Seresto Usage
Video
Vet Review When the Activyl product line came out several years ago, it was touted as a totally novel new product on the market that would not have the problems of emerging flea resistance to products that has believed to been increasing in recent years with the old standby products in some cases. It supposedly works through a unique process of bioactivation using only the flea enzymes in activating the main ingredient, indoxacarb, in killing fleas. Along with the permethrin ingredient for tick coverage and control, it would seem like this would be a first line or excellent choice for those looking for a novel and comprehensive flea/tick product for their dogs. And while it is also effective in preventing flea eggs and larvae from developing as well, and can be highly effective in today's war against fleas and ticks, I have seen occasional problems with this product, as reported by clients. While its deeper penetration in the fatty oils of the skin may be a benefit, and while the product is not reported to be absorbed systemically, I have seen occasional and severe side effects reported by animal guardians. As with most other topical products in this venue, this particular product can occasionally cause irritation and itching at the site of application, which while usually only transient for a day or two, in some pets the itching and allergic reaction has been noted to intensify, necessitating anti-itch medications for relief. Some clients have also reported an odd odor from the application site for a while, as well as an oily film, which may persist for a few days. While many clients do report this product highly effective when other competitor products may have failed them recently, these occasional reactions are important to note, especially in a very sensitive or geriatric animal, and/or one with a chronic medical condition. On very rare occasions, clients have reported digestive side effects, as well as rare neurological weakness, stiffness or even spasms. While the vast majority of clients are satisfied with this product's performance and reliability, the decision on using this stronger, newer way of flea and tick control, should be made after careful consideration of patient history, as well as discussion with the local veterinarian. I give this product an overall rating of a 4, with an ease of use of a 5, with a mid-rating safety level of 3. In recent years, the company Bayer has developed a revolutionary flea/tick collar for both dogs and cats that is highly effective, especially in flea control, as well as providing moderately effective tick control. The most exciting aspect of this product is that it provides BOTH repelling and killing of fleas and ticks for up to 8 months!! While it is somewhat expensive, it is actually cheaper than purchasing 8 months of Revolution, Advantage or Frontline. In many areas of the country, this protection will last the entire flea and tick season, by just properly applying the collar. Another major advantage over collars developed in prior years (i.e. Preventic collar) is that Seresto is water resistant, and can be worn with confidence, even by dogs who frequently swim. The collar also has no odor, as well as a powdery, soft feel, in addition to leaving no greasy topical residue, like many of the other topical flea and tick products available. The collar is safe if chewed and/or even eaten by the pet, which was a problem with the old Amitraz based collars such as the Preventic collar. The Bayer company has also made it radioopaque, in case an overzealous pet did ingest the collar, so as to allow radiographic tracing and/or location should it possibly get caught up in the intestinal tract. The collar also has unique technology, in that the release of the active ingredients is triggered by friction of the movement of the pet's hair and body heat. The cat collar even has a break-away apparatus to allow for the pet to safely detach from the collar should it get caught on something outside. The reflectors on the dog product also allow the dog to be seen during the hours of darkness. While the collar is very safe for most pets, I have occasionally and rarely seen reactions in sensitive, geriatric or chronically ill pets. These typically involve transient itching, redness and hair loss at the site of adherence to the skin. While most of the time this will resolve on its own in a week or two, occasionally pets will develop enough irritation where the collar may need to be removed. The major rare systemic reactions seen in sensitive pets are mild lethargy and decrease in energy, but even more rare is the development of neurological symptoms, including weakness and/or seizures. I don't recommend that it be used in pets with a history of seizures and/or neurological sensitivity or reactions. While it is amazing for killing and repelling all stages of the flea life cycle quite quickly, it can sometimes take up to several days for the maximal effects to be seen with tick control and prevention. I, therefore, give this product an overall rating of a 4 out of 5, with an ease of compliance and efficacy of a 4.5 out of 5.
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.

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