Sentinel vs. Seresto Comparison

Sentinel

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Seresto

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Kills Fleas

Repels Fleas

Kills Flea eggs and Larvae

Prevents Development

Kills Ticks

Repels Ticks

Kills and/or Repels Mosquitoes

Prevents Heartworm

Other Parasites Information

Controls adult hookworms and removes and controls adult roundworms & whipworms

Kills biting lice plus aids in the treatment & control of sarcoptic mange on dogs.

Waterproof (shampooing once a week can reduce effectiveness)

N/A

Safe for pregnant or nursing Pets

Consult veterinarian before use.

How long does it take to work

Begins to work Immediately, However, pre-existing flea populations may continue to develop and emerge.

Kills fleas within 24 hours, and reinfesting fleas are killed in 2 hours. Reinfesting ticks are repelled and/or killed in 6 hours.

Taste

Beef Flavor

Collar

Active Ingredient(s)

Milbemycin Oxime/Lufenuron

Flumethrin, Imidacloprid

RX Required

Dosage

Usage

Video

Coming soon

Vet Review

Sentinel is a wonderful combination of the heartworm prevention pill interceptor and the flea control product program both in this one pill. Many clients enjoy the convenience of having such broad acting internal and external parasites in one pill, without having to worry about giving two separate medicines. Lufenuron, which is the main flea control ingredient, stops the flea life cycle in its track at the egg and larval stage, thus being like a birth control pill for fleas who get on our pets. Given that the main problem of fleas is how rapidly they reproduce, this pill literally stops escalating growth of flea populations, before they can become established in our homes, where most of the flea life cycle occurs. The main disadvantage to this product is that it does not kill or repel adult fleas, so in situations with already established heavy infestations, it is best combined with a great topical product like advantage or front line or with the oral adulticide flea pill Capstar for maximal effect. The only other rare disadvantage I see is the slight increase in reactions when two products are combined into one like this, but fortunately this is not common in clinical practice. With milbemycin for prevention of heartworms and controlling and treating most common intestinal worms, I overall highly recommend this versatile product.

In recent years, the company Bayer has developed a revolutionary flea/tick collar for both dogs and cats that is highly effective, especially in flea control, as well as providing moderately effective tick control. The most exciting aspect of this product is that it provides BOTH repelling and killing of fleas and ticks for up to 8 months!! While it is somewhat expensive, it is actually cheaper than purchasing 8 months of Revolution, Advantage or Frontline. In many areas of the country, this protection will last the entire flea and tick season, by just properly applying the collar. Another major advantage over collars developed in prior years (i.e. Preventic collar) is that Seresto is water resistant, and can be worn with confidence, even by dogs who frequently swim. The collar also has no odor, as well as a powdery, soft feel, in addition to leaving no greasy topical residue, like many of the other topical flea and tick products available. The collar is safe if chewed and/or even eaten by the pet, which was a problem with the old Amitraz based collars such as the Preventic collar. The Bayer company has also made it radioopaque, in case an overzealous pet did ingest the collar, so as to allow radiographic tracing and/or location should it possibly get caught up in the intestinal tract. The collar also has unique technology, in that the release of the active ingredients is triggered by friction of the movement of the pet's hair and body heat. The cat collar even has a break-away apparatus to allow for the pet to safely detach from the collar should it get caught on something outside. The reflectors on the dog product also allow the dog to be seen during the hours of darkness. While the collar is very safe for most pets, I have occasionally and rarely seen reactions in sensitive, geriatric or chronically ill pets. These typically involve transient itching, redness and hair loss at the site of adherence to the skin. While most of the time this will resolve on its own in a week or two, occasionally pets will develop enough irritation where the collar may need to be removed. The major rare systemic reactions seen in sensitive pets are mild lethargy and decrease in energy, but even more rare is the development of neurological symptoms, including weakness and/or seizures. I don't recommend that it be used in pets with a history of seizures and/or neurological sensitivity or reactions. While it is amazing for killing and repelling all stages of the flea life cycle quite quickly, it can sometimes take up to several days for the maximal effects to be seen with tick control and prevention. I, therefore, give this product an overall rating of a 4 out of 5, with an ease of compliance and efficacy of a 4.5 out of 5.

Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.