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Advantage II - Bio Spot For Cats
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Advantage II
Bio Spot For Cats
Kills Fleas checkmark checkmark
Repels Fleas X mark X mark
Kills Flea eggs and Larvae checkmark Flea eggs
Kills Ticks X mark checkmark
Repels Ticks X mark X mark
Kills and/or Repels Mosquitoes X mark checkmark
Prevents Heartworm X mark X mark
Other Parasites Information Treats, Prevents, and Controls Lice Infestations X mark
Waterproof (shampooing once a week can reduce effectiveness) checkmark X mark
Safe for pregnant or nursing Pets Consult your veterinarian Consult your veterinarian
How long does it take to work Kills fleas in 12 hours 1-2 days.
Taste Applied to Skin Applied to Skin
Active Ingredient(s) Imidacloprid/Pyriproxyfen (S)-Methoprene/Etofenprox
RX Required X mark X mark
Dosage
Usage Advantage II Usage Bio Spot For Cats Usage
Video /images/products/video/petmeds-flea-preventative-advantage.flv
Vet Review The non-greasy, non-odor formulation is a definite plus when used on sensitive patients, especially cats. I find that advantage kills fleas and larvae more quickly than some of the other products out there,  often resulting in quicker relief of flea allergy dermatitis symptoms in dogs and cats. Overall I have found it quite safe and have seen the fewest topical or rare systemic reactions in my practice over the years.  The main disadvantage I have found is that in heavy flea infestations that the efficacy may wear off in less than one month, necessitating some vets to recommend more frequent off label use of this product every few weeks.  It also does not control ticks as well on dogs and cats.  I find that advantage works most effectively when combined with good environmental flea control at home. While an economical alternative to the more expensive topicals like Advantage or Frontline, because of safety concerns I cant recommend this product to my clients. Over the years I have seen too many side effects from topical irritation to rare and sometimes severe neurological and/or seizures in some pets. I have also found it to not be as effective in flea control as with advantage or front line. While it is marketed to work against adult fleas,  prevent development of flea eggs into larvae and adults, as well as killing ticks for 3 months, once an infestation is in place  I have not found this product to be as effective as the competitors in my opinion and experience. One of the nice few benefits I have seen is the killing and repelling of mosquitoes with use of this spot on product.  While it is easy to apply and water based, many of my clients have reported irritation reactions as well as greasy fur at the site of application.  It is for these reasons that I give this product an overall rating of a 2 with an efficacy of a 2 with ease of use a 5.
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.

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