Compare

Activyl - Simparica
Call Us: 1-800-738-6337
Activyl
Simparica
Kills Fleas checkmark checkmark
Repels Fleas X mark X mark
Kills Flea eggs and Larvae checkmark X mark
Kills Ticks X mark checkmark
Repels Ticks X mark X mark
Kills and/or Repels Mosquitoes X mark X mark
Prevents Heartworm X mark X mark
Other Parasites Information NA X mark
Waterproof (shampooing once a week can reduce effectiveness) checkmark N/A
Safe for pregnant or nursing Pets X mark The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs.
How long does it take to work Reapply Activyl every 30 days. Begins to kill adult fleas within 3 hours and ticks within 8 hours of administration.
Taste Applied to skin Liver flavor
Active Ingredient(s) indoxacarb sarolaner
RX Required X mark checkmark
Dosage
Usage Activyl Usage Simparica Usage
Video Video coming soon
Vet Review Another recently available new topical flea preventative for dogs and cats. This new product works by being activated by only the flea's enzyme systems into a flea specific mechanism which paralyzes and kills the adult flea. The company claims that it does not get into the blood stream, but stays only in the superficial skin layers of the pet. Any adult fleas which come into contact with this product are quickly killed so that fleas do not have to actually bite the pet, which is tremendously helpful in those flea-allergic pets, where it only takes a few flea bites to set off an extensive itchy allergic reaction. Another wonderful benefit of this product is that it is waterproof, which is especially helpful in those active outside pets who are exposed to rain or like to swim. This effective product starts working within 12 hours of application, where over 90% of adult fleas are killed. Another excellent benefit of this product is that it also inhibits the development of flea eggs and larvae in the environment, which is a big bonus since much of the flea life cycle occurs in the home environment. While Activyl is very safe and effective for most pets, I have seen occasional rare reactions in sensitive pets, which most commonly is seen as irritation or excessive itchiness at the site of application. While the company says that it is odorless, some of my clients have said that they do sense an odor within the first several days of application, as well as leaving an occasional oily film for the first day or two following application. This film, however usually quickly disappears. The only other very rare reactions include digestive upset and/or drooling/neurological reactions, and certainly if a pet has any chronic digestive weaknesses or history of seizures, etc then the local veterinarian should be consulted before applying the product. I give this product an overall rating of 4, with an ease of use of 4. Within the past few years, we have seen a surge of new flea and tick parasiticides for dogs and cats, especially important as we are discovering increased transmission of health-threatening disease to our animal companions. In the past year, the very trustworthy and reliable pharmaceutical company Zoetis has come out with a revolutionary liver flavored chewable tablet, Simparica, that is highly effective against fleas and multiple species of ticks. Compared to similar oral tablets, as well as other topical products, I find that Simparica works even more quickly than competitor products, starting to kill fleas within 3 hours, and ticks within 8 hours. Unlike other products labeled for monthly use, studies and my clinical experience show that Simparica is actually effective up to 35 days, not dropping off in efficacy as many other products do in killing fleas and ticks toward the end of the month. I also find that the many flexible dosing packages offer convenience to canine guardians, even in small dogs who weigh under 5 pounds. In addition to the efficacy against fleas and ticks, the product is also labeled effective against scabies mites. Many veterinarians and dermatologists are also now reaching for Simparica as a quick, safe and effective off-label treatment of demodex mange mites, which have long been very difficult to manage in veterinary medicine. I have found that in many cases one dose of Simparica will clear up many demodex mange cases within one month of the first pill. I have found that most dogs tolerate this product very well, especially when given with food. I have occasionally seen mild digestive upset in some sensitive pets, as well as rare neurological reactions. If a dog has a history of seizures, I would probably be cautious in using this product or ones of a similar class. Most dogs readily take this chewable tablet. I give this product an overall rating of a 4.5, with an efficacy of 4.5, and ease of use a 4.5.
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.

Most Recent Comparisons

Previous Month October 2020
Sun Mon Tue Wed Thu Fri Sat
1 2 3
4 5 6 7 8 9 10
11 12 13 14 15 16 17
18 19 20 21 22 23 24
25 26 27 28 29 30 31