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$3.68 $2.50 per tablet
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100 mg Tablets
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$3.68 $2.50 per tablet
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100 mg Tablets
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Product Info

What is Fluconazole?

Fluconazole is an antifungal medicine in tablet form that is used to treat a variety fungal infections, including yeast infections. It is typically used to treat skin infections, and more intense fungal infections of the lungs and other organs that can occur after your pet inhales fungus from infected soil. Fluconazole is often used in pets who have been unable to tolerate other types of antifungal medication. It is also used for difficult-to-treat fungal infections, such as those that have spread to internal organs. Fluconazole is an antifungal used to treat systemic fungal infections such as cryptococcal meningitis, blastomycosis, and histoplasmosis. Fluconazole may also be used in treating fungal infections of the skin such as superficial candidiasis, or ringworm. Fluconazole may be used for other purposes than those listed here. Fluconazole is sold per tablet and requires a prescription from your veterinarian.

NOTE: Ketoconazole is also available for treatment of fungal infections.


Cats and Dogs


  • Treats a variety of internal and external fungal infections
  • Treats serious fungal infections of the central nervous system (CNS) more effectively than many other antifungals
  • Has fewer side effects than most other antifungals
  • Is effective against ringworm

How does fluconazole work?

Fluconazole is related to ketoconazole, but it is more successful in treating infections of the central nervous system (CNS) because it more effectively crosses the blood-brain barrier, allowing the medication to find its way to the infected areas of the body. When your pet takes fluconazole, the active ingredient within the medicine kills the fungus that causes infections by interfering with the cell membranes of the fungus. This inhibits growth of the fungus, which keeps the fungal cells from reproducing, and eventually eradicates the infection.


Fluconazole can interact with many other drugs. It is important to tell your veterinarian about any other medications, vitamins, or supplements your pet is taking before giving fluconazole to your pet. Do not give to pets who have liver disease or impairment. If your pet has kidney disease or kidney failure, discuss the risks versus benefits with your veterinarian before giving fluconazole. Do not give to pregnant pets or pets that are nursing unless your veterinarian says the benefits outweigh the risks. Do not give fluconazole to any pets who are sensitive or allergic to other "azole" antifungal medications, such as ketoconazole. If you have any concerns about this medication, talk with your veterinarian before giving it to your pet.

Brand Name:

Diflucan (Pfizer)

Generic Name:


What is the most important thing I should know about fluconazole?

Fluconazole is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to use this medication in dogs and cats.

What should I discuss with my veterinarian before giving fluconazole to my pet?

Do not give this medication if your pet is allergic to fluconazole or other azole antifungal agents. Do not use fluconazole if your pet is pregnant unless the benefit outweighs the risk. Tell your veterinarian if your pet is allergic to any medications, or if your pet has liver disease or kidney disease.

How should fluconazole be given?

Give fluconazole exactly as it was prescribed by your veterinarian. Do not give in larger amounts or use it for longer than recommended by your veterinarian. Follow the instructions on the prescription label. If you do not understand these directions speak to your pharmacist or veterinarian. The usual dose of fluconazole in dogs can vary from 5.5 mg to 22 mg/lb of pet's weight every 12 to 24 hours, depending on the condition being treated. The usual dose in cats is typically 50 mg once a day. The actual dose and duration of treatment depends on the specific condition being treated. Fluconazole should be given to your pet for the entire length of time prescribed by your veterinarian. Treatment with fluconazole may take several months and improvement may not be seen for one or two weeks after treatment begins. Your veterinarian may want to perform blood tests on a regular basis to make sure the medication is not causing harmful effects.

What are the potential side effects of fluconazole?

Seek emergency veterinary medical attention if your pet experiences any signs of an allergic reaction (hives; difficulty breathing; swelling of the face, lips, tongue, or throat). Talk to your veterinarian immediately if your pet develops any of these side effects: jaundice, loss of appetite, vomiting, depression, tiredness, anemia, skin rash. Talk to your veterinarian about any side effect that seems unusual or that is especially bothersome to your pet.

What happens if I miss giving a dose of fluconazole?

Give the missed dose as soon as you remember. However, if it almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication.

What happens if I overdose my pet on fluconazole?

Seek emergency veterinary medical attention if you think you have used too much of this medication. Symptoms of overdose may include loss of appetite, vomiting, jaundice, depression, tiredness, anemia, or a skin rash.

What should I avoid while giving fluconazole?

Do not use fluconazole in animals with liver disease. Use with caution in pets with kidney disease. Do not use in pregnant pets unless the benefit outweighs the risk.

What other medications will affect fluconazole?

Tell your veterinarian if your pet is using any of the following medications: Buspirone, cisapride, cyclophosphamide, cyclosporine, thiazide diuretics (Dyazide, Diuril), NSAIDS (Rimadyl, Novox), theophylline/aminophylline, tricyclic antidepressants (clomipramine, Clomicalm, amitriptyline), sulfonylurea ant-diabetics (glipizide, glyburide), warfarin (Coumadin). There may be other drugs not listed that can affect fluconazole. Tell your veterinarian about all prescription and non-prescription (OTC) medications, including vitamins, minerals, herbal products, and drugs prescribed by other veterinarians. Do not start using a new medication without telling your veterinarian.

How to Use

Fluconazole Directions:

  • Give fluconazole to your pet with food and always make sure your pet has plenty of fresh water to drink while taking this medication.
  • Do not give fluconazole within 2 hours of giving antacids because it could affect the dosage your pet receives.

You may not notice a visible improvement until you've been treating your pet for 1 to 2 weeks, and you may need to treat your pet with fluconazole for several months. Make sure you continue giving the prescription to your pet until the end of the treatment regimen unless your veterinarian specifically directs you to discontinue giving fluconazole. Your pet may feel better, and you may notice an improvement in visible fungal infections before the treatment has ended, but it's important to complete the treatment to prevent a relapse and to prevent the possibility of future resistance to fluconazole or other antifungal medications.

All weights
Dosage and how frequently you will need to administer the medication depends upon the particular infection being treated. Follow your veterinarian's instructions.
Do not use!

Store this product at room temperature in child-proof containers. Keep out of reach of children and pets.


Fluconazole Ingredients:

Active Ingredients
100 mg
Customer Reviews
Fluconazole is rated 4.0 out of 5 by 3.
Rated 4 out of 5 by from Much less expensive elsewhere I found this same drug and dose for one dollar a pill at allivet My dog has lupus and constantly gets skin infections and this helps some, but doesn't take the infections altogether away.
Date published: 2017-03-12
Rated 3 out of 5 by from Valley Fever Max was diagnosed with Valley Fever and this medication was prescribed to get rid of the Valley Fever. It is difficult to determine if he is getting better as the symptoms Max is experiencing the same symptoms as the side effects of the medication. Loss of appetite, depression, weak, weight loss. This is only the first week. He is prescribed to continue this med for at least six months. Will continue to monitor and update weekly.
Date published: 2017-01-10
Rated 5 out of 5 by from Works great My 8 mth old puppy has food allergy and developed a secondary yeast infection. Worked great on clearing it right up! Great price too!!!!
Date published: 2011-09-12
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I have to go out of town and there isn't anyone that can give my cat his dosage. Is there a danger with him missing 2-3 doses in a row? He's been taking it since 11-3-17. His is a liquid that is compounded.

Asked by: TXKay
Thank you for your question. The danger with your pet not taking his doses is that his infection could get worse. There are places available that will board pets while their owners are out of town for a very reasonable fee and they will give your pet his medication, which is something you may want to consider. I hope this helps!
Answered by: Adriane
Date published: 2017-12-13

Is this for fever in dogs

Asked by: John
This is not for fever in dogs. Some conditions that cause fever however could be treated with this medication therefore reducing the fever. This medication must be prescribed by a veterinarian for a specific type of infection. If you have any more questions about this please call your 1800PetMeds Pharmacist or your veterinarian.
Answered by: 1800Petmeds Pharmacist
Date published: 2016-12-21

Brand name

Is the fluconazole that you sell manufactured by Pfizer or is it generic?
Asked by: schnitzelwitz7
Diflucan is the brand name of the generic medication Fluconazole. We do not sell Diflucan, only the generic. It is manufactured by Glenmark.
Answered by: Christine
Date published: 2016-10-21

can this help with valley fever?

Asked by: greg2511
Valley Fever (coccidioidomycosis) usually requires treatment with long term anti-fungal therapy. Ketoconazole is commonly used to treat dogs with valley fever. Fluconazole may also be effective. These both require prescriptions from your veterinarian.
Answered by: Christine
Date published: 2016-10-20

My English bulldog has a serious ear infection. He had this before and the vet prescribed clindamycin 300mg 2x's a day. So, is that literally 4pills of the 150mg ? Also I think he was prescribed fluconazole but I'm not sure, so are.those 2 compatible?

Asked by: Pampam
Yes, taking 4 of the Clinamycin 150 mg pills is equivalent to taking 2 of the 300 mg pills. There is no interaction between Fluconazole and Clindamycin, so these can be taken together if prescribed by your veterinarian.
Answered by: Christine
Date published: 2016-10-18

My English bulldog has a serious ear infection, besides clindamycin, should I use a ear drop liquid and if so what kind?

Asked by: Pampam
Yes, ear infections are typically treated with antibiotic ear drops. These require a prescription from your veterinarian. Your vet would be able to determine which antibiotic ear drop is best for your bulldog after assessing them.
Answered by: Christine
Date published: 2016-10-18

my little dog is on the 40mg of Fluconazole. for valley fever. she will be on this medication for at least 12 months or longer.I can't seem to find the pricing for this mg. how do I find it.

Asked by: linkeogh
Unfortunately, we only have 100 mg tablets available. However, we also carry Fluconazole liquid 50 mg/mL. Giving your dog 0.8 mL would equal 40 mg. The link to the Fluconazole liquid is listed below.
Answered by: Christine
Date published: 2017-11-06

dosage for 7lbs daushand of fluconazle 

Asked by: jack
Dosage and how frequently you will need to administer the medication depends upon the particular infection being treated. Follow your veterinarian's instructions.
Answered by: paulpharmacistintern
Date published: 2016-08-13
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