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Denamarin Chewable Tabs

$55.56 $38.99 
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Dogs 30 ct
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$55.56 $38.99 
Ships in one business day or less

Step 1. Select an Option:

Dogs 30 ct
Price w/coupon SAVE20
You save $16

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Please select all product options.

Step 2. Select a Quantity:

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Product Info
What are Denamarin Chewable Tablets?

Denamarin Chewable Tablets are a nutritional supplement containing S-Adenosylmethionine (225 mg) and Silybin (24 mg) to provide a multi-faceted approach to liver support.



  • Supports healthy liver function by raising antioxidant levels
  • Silybin aids digestion and absorption of nutrients from your pet's diet
  • Tasty pork liver flavored chewable tablet
  • No known side effects
How it works:

Denamarin combines pure S-Adenosylmethionine (SAMe) with Silybin to provide a one-two punch to keep your pets liver healthy. Silybin supports the flow of bile through the liver which helps with the digestion and absorption of nutrients from your pet's diet. Silybin also helps to regenerate liver cells and may enhance levels of glutathione, an antioxidant that helps to protect cells from toxins such as free radicals. It comes in a pork liver flavored chewable tablet that most dogs love.


Store in a cool dry place, not to exceed 86°F.

Brand Name:


Active Ingredient(s):

S-Adenosylmethionine (225 mg), Silybin A+B (24 mg)

What is this product used for:

Denamarin Chewable Tablets for dogs of all sizes is a patented nutritional supplement for veterinary use in dogs. Denamarin combines a pure and stabilized S-Adenosylmethionine with Silylbin to provide a multi-faceted approach to liver support.


Denamarin Chewable Tablets is a non-prescription (OTC) product available in bottles of 30 liver flavored chewable tablets for dogs of all sizes.

How this product should be used:

The daily dose for dogs up to 6 lbs is 1/4 tablet. For dogs 7-15 lbs give 1/2 tablet. For dogs 16-30 lbs give 1 tablet. For dogs 31-45 lbs give 1 nad 1/2 tablet. For dogs 46-60 lbs give 2 tablets. For dogs 61-75 lbs give 2 and 1/2 tablets. For dogs 76-90 lbs give 3 tablets. For dogs 91-105 lbs give 3 and 1/2 tablets, and for dogs over 105 lbs give 4 tablets. The tablets should be given on an empty stomach at least one hour before a meal for optimal absorption. For owners who find it difficult to administer tablet(s) to their pets, Denamarin may be disguised in a small bite of food. The number of tablets administered may be gradually reduced, or increased, at any time at the recommendation of your veterinarian.

What are the side effects:

There are no reported side effects when used in dogs.

What special precautions are there:

This product is for veterinary use in dogs only. Denamarin Chewable Tablets should be given on an empty stomach at least one hour before a meal for optimal absorption. Denamarin Chewable Tablets are sensitive to moisture and heat. The bottle contains 1 non-toxic desiccant to help preserve freshness and ensure the shelf life of the product.

In the event of overdose:

Contact your veterinarian or veterinary emergency room.

How should I store this product:

Store in a cool dry place not to exceed 86 F. Keep bottle closed with desiccant inside when not removing tablets. Tablets are sensitive to moisture and heat.

How to Use

Denamarin Chewable Tabs Directions:

  • Please refer to the chart below for dosing recommendations.
  • The number of chewable tablets administered may be gradually reduced, or increased, at any time at the recommendation of your veterinarian.

The tablets should be given on an empty stomach at least one hour before a meal for optimal absorption.

Denamarin Chewable Tabs Dosage:

Denamarin Chewable Tabs Dosage for Dogs
Up to 6 lbsGive ¼ tablet
7-15 lbsGive ½ tablet
16-30 lbsGive 1 tablet
31-45 lbsGive 1 ½ tablets
46-60 lbsGive 2 tablets
61-75 lbsGive 2 ½ tablets
76-90 lbsGive 3 tablets
91-105 lbsGive 3 ½ tablets
Over 105 lbsGive 4 tablets
Denamarin Chewable Tabs Dosage for Horses
Do not use!
Denamarin Chewable Tabs Dosage for Cats
Do not use!

Store in a cool dry place, not to exceed 86°F.


Denamarin Chewable Tablets for Dogs Ingredients:

Denamarin Chewable Tablets for Dogs
Active Ingredients (per tablet)Amount
S-Adenosylmethionine225 mg
Silybin A+B24 mg
Customer Reviews
Denamarin Chewable Tabs is rated 4.0 out of 5 by 11.
Rated 5 out of 5 by from Life Saver My 14 year old miniature dauschund was having seizures due to a faulty liver. My vet recommended this. After one month of taking this, she is back to her old self, her seizures have decreased to bout only 1 a month, and her liver blood results have not gotten worse. Thank God for this miracle in a bottle!!1
Date published: 2017-03-28
Rated 1 out of 5 by from Not palatable for my dog My dog will not ingest this product as he finds the taste unpalatable. The first time I tried to give it to him he spit the tablet back out. He would not even attempt to take it on future attempts as he does not consider it food. This is even the one of my dogs that will eat almost anything. The tablet is too large to fit down his throat without breaking it up and I don't want to force a jagged shaped pill down his throat. Next time don't sell a "chewable" product that dogs don't want to chew.
Date published: 2017-01-21
Rated 5 out of 5 by from It works My dog is 16 years old and has "stable" Cushings. His started taking Denamarin several months ago, and blood test a couple weeks ago shows his liver function has improved, considerably.
Date published: 2016-11-20
Rated 4 out of 5 by from Huge pills I am convinced that these will help my dog, who has Cushings disease and is recovering from an Erlichia infection. The problem is how to get him to take them. He is supposed to take two chewable tablets, but they are each as big around as a penny! He doesn't like the smell and is suspicious of medications right now and they are too big to hide in a piece of sausage. I ground it up and mixed it with chicken, but after a close examination he wouldn't eat it. Any ideas how to get him to eat even one pill? He normally eats anything, but not since being sick.
Date published: 2016-02-18
Rated 5 out of 5 by from Impressed! I really think these work. Our Miniature Schnauzer is almost 15 years old and last year we noticed he wasn't doing as great as he normally was although he has a great diet and lives the comfy life. We just thought it was his age. The vet mentioned something about his liver enzymes being very low and suggested this. It was worth a shot in the name of his health although our first thoughts were that this was expensive and we were skeptical. After a month we noticed his health really improve. He loves these and he is doing fabulous. We really notice a difference in his overall behavior. He has even started playing again. We will certainly keep up the supplementation.
Date published: 2012-11-11
Rated 5 out of 5 by from Decreased her liver enzymes 14 year old border collie with elevated enzymes and bad breath. After 4 weeks of taking chewables breath was much better and her levels came down!! Keeping her on them! Probably will extend her life!!
Date published: 2012-07-18
Rated 5 out of 5 by from Denamarin My Chihuahua has been on Denamarin for about 4 years now and I am convinced that it has helped to spare her life! She has a liver shunt and toxicity levels in her body were extremely high. We tried this as a "last ditch effort" to improve her liver functioning - 4 years later I am happy to report that she is a happy healthy girl!!!
Date published: 2012-04-12
Rated 3 out of 5 by from high liver enzymes My dog Princess has had high liver enzymes. I was at a loss of what to do. I was told there was nothing I could do, but then got online and asked some vets and they suggested an ultrasound so against my vets advise I did and found that she had lobes in her liver. We are not sure if they are cancerous or not but that is prob. why her liver enzymes are high. Also her kidneys are not filtering quite as effectively as they should So I put her on Science Diet kidney function and after a couple of months I took her in for a blood panel and her liver enzymes have come down a lot. Not completely where they should be but quite a lot. You may want to try this since all of the organs work together. I am going to try this to see if it helps to get the liver enzymes down even further.
Date published: 2011-12-07
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My dog has diabetes, do the chewable contain sugar.

Asked by: Kellyh
Thank you for your question. The ingredients in Denamarain are S-Adenosylmethionine and Silybin A+B. S-adenosylmethionine (also known as SAMe) is a manmade form of a chemical that occurs naturally in the body. SAMe has been used in alternative medicine as a likely effective aid in reducing the symptoms of depression, and in treating osteoarthritis.Flavonolignans from milk thistle (Silybum marianum) .
Answered by: Crystal PetMed Pro
Date published: 2017-11-15

My dog is 24 lbs. he has quite a few fatty tumors all over. He is 15 yrs old. They are not cancererous. Would this be be something if he was take help get rid them.

Asked by: Martha
Denamarin is a liver support supplement. It is best to consult with your vet in regards to what they would recommend for your furbaby who has fatty tumors.
Answered by: Crystal PetMed Pro
Date published: 2017-08-28

What is the recommended length of treatment?

Asked by: nanner
Hello, please speak to your Vet about how long they want your pet on this product.
Answered by: Roseanna Pharmacy Intern
Date published: 2017-04-18

Denamarin chewable

My dog loves these but our vet mentioned that the non-chewable were individually wrapped so they would be more effective. Are they actually better?
Asked by: Sal
The active ingredients are the same for the regular tablets and chewable tablets, so they should be just as effective.
Answered by: Christine
Date published: 2017-10-15

do you have denamarin in the 75 tblet bottle

Asked by: Judy
I'm so sorry, we only have the denamarin available in 30 ct. bottles.
Answered by: Cherley Petmeds Pro
Date published: 2016-01-24

Can I give my 15 lb. cat, 1/2 of a Denamarin chew-able tablet?

My 15lb cat loves treats, but is not so thrilled about being pilled. (He is on one Denamarin for small cats and dogs once a day.) If I could get him to take 1/2 of a chewable as a "treat", it would make our lives much happier. But I don't want to overdose him. If my math is correct, it seems that this ( 1/2 chewable tablet )would be OK. If it is, I'll tgive it a try.
Asked by: ski
Please consult with your veterinarian as the Chews are not indicated to be used in cats by the manufacturer.
Answered by: Lilli Pharmacist
Date published: 2015-09-22

Use for cats

I noticed someone else asked if this can be used for cats and the answer was no. Could someone please explain why. It's the exact same ingredients just higher mg.-couldn't you just cut them into quarters or halves? I have a cat that will not take the reg pill and the "Marin" product that was suggested does not have the same active ingredients. Thank you!
Asked by: LB
The answer given by the staff doesn't really make any sense since the directions instruct you to cut the pills into quarters or halves depending on your pets' weight. I have a 3lb Chi who is on this same supplement. I cut his into quarters
Answered by: pommom1016
Date published: 2015-04-14

My Chihuahua will not swallow the Denamarin tablets. He will not chew the chewable tablets either.

I have been crushing 1/4 chewable tablet and mixing with peanut butter or spray cheese. I worry that he may not be absorbing the supplement because it is mixed with food. I don't know how to administer it any other way. Does anyone have a suggestion to administer another way?
Asked by: Maura
yes, I had problems with my dog taking pills in general, I went to the pet store and purchased pill pockets. I have had no issue , he thinks he is getting a treat. Switch up on flavors, to keep him interested.
Answered by: suzie
Date published: 2017-04-30
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