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Monthly heartworm and flea prevention in the convenience of a tablet.
 
  • Prevents heartworm disease
  • Controls flea population
  • Controls hookworms
  • Removes and controls roundworms
  • Removes and controls whipworms
  • Beef flavor tablet
  • For dogs only
  •  
     
     

    Sentinel

     
    Q & A
    Starts at $42.99 Ships in one business day or less
    1_Select a Weight
      Dogs:




       
     
     
      Product Info   How to use   Ingredients   Customer Reviews   Q & A  

    What is Sentinel?

     

    Sentinel is the only monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Sentinel requires a prescription from your veterinarian.

    For:
    Dogs
     
    Benefits:
    Comes in palatable flavored tabs
    Easy to administer just once a month

    How it works:
    Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle.

    Sentinel may be given along with Capstar, which treats flea infestation.

    Cautions:
    Side effects are rare, though some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, or seizures. If these or other symptoms develop contact your veterinarian. Its important to maintain good personal hygiene, since humans can contract hookworms and roundworms. Its also important to eliminate fleas and to not feed your pet uncooked meat or fish. To prevent re-infection, clean up stools on a daily basis. Consult your veterinarian for pregnant or lactating dogs.


    More Information:
    Brand Name
    Sentinel (Novartis)
    Generic Name
    Milbemycin Oxime (milí-beh-myí-sin oxí-eem) and Lufenuron (lew-fení-your-on)

    What is the most important information I should know about Sentinel: Sentinel is a prescription medication FDA-approved for use in dogs. Sentinel is available as artificial beef flavored (derived from pork and soy protein) chewable tablets. This medication should be given once a month year-round.

    What is Sentinel: Sentinel is given once a month for the prevention of heartworm disease in dogs. Sentinel also protects against hookworms, roundworms, and whipworms. Sentinel is also used to control fleas by preventing the development of flea eggs. Sentinel does not kill adult fleas. The American Heartworm Society recommends that heartworm prevention be used year-round. Sentinel may also be used for purposes other than those listed in this guide.

    What should I discuss with my veterinarian before giving Sentinel to my pet: Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

    How should this medication be given: Give Sentinel exactly as directed by the veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Sentinel for dogs 2 to 10 pounds is 2.3mg/46mg, 11 to 25 pounds is 5.75mg/115mg, 26 to 50 pounds is 11.5mg/230mg and 51 to 100 pounds is 23mg/460mg given once a month year-round. For dogs over 100 pounds give the appropriate combination of tablets. Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Sentinel for 6 months or less, re-start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Sentinel at room temperature. Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Consult your veterinarian for pregnant or lactating dogs.  

    What happens if I miss giving a dose: Give the missed dose as soon as you remember. Do not give a double dose of the medication.

    What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include depression, drowsiness, vomiting, loss of appetite, diarrhea, hypersalivation, seizures, and weakness.

    What should I avoid while giving Sentinel to my pet: Because humans can contract hookworms and roundworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household and to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.

    What are the possible side effects of Sentinel: Side effects of Sentinel are rare although some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, hypersalivation, seizures, and weakness. If these or other symptoms develop contact your veterinarian.

    What other drugs will affect Sentinel: While Sentinel is safe to use in dogs at risk for MDRI-allele mutation (Australian Shepherds, Collies, Shelties,etc.), unless tested normal, caution is advised if the pet is also being given amiodarone (Cordarone), azole antifungals such as ketoconazole, carvedilol (Coreg), cyclosporine (Atopica), diltiazem (Cardizem), erthromycin (Ery-Tabs) or clarithromycin (Biaxin), quinidine, spironolactone (Adlactone), tamoxifen, and verapamil (Calan). Do not give Sentinel to your pet if already giving an alternate heartworm medication.

    Where can I get more information: Your pharmacist has additional information about Sentinel written for health professionals that you may read.

     

    Directions:
    Give Sentinel Flavor Tabs once a month on the same day of each month year-round.
    Sentinel Flavor Tabs is for use in dogs only. Do not give to cats.
    Watch your dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.
    Tip: Do not remove Sentinel from its wrapper until ready to give to your pet.
    Dosage:
    Pet Weight Dosage
    Dogs/puppies: (4 weeks of age or older)
    2-10 lbs Give 1 Flavor Tab every month
    (Brown Box)

    11-25 lbs Give 1 Flavor Tab every month
    (Green Box)

    26-50 lbs Give 1 Flavor Tab every month
    (Yellow Box)
      51-100 lbs Give 1 Flavor Tab every month
    (White Box)

    Over 100 lbs Give combination of Flavor Tabs based on weight
    Cats:
    Horses:
    Storage: Should be stored at room temperature between 59° and 77° F.
    Sentinel Brown for Dogs 2-10 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 2.3 mg
    Lufenuron 46 mg

    Sentinel Green for Dogs 11-25 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 5.75 mg
    Lufenuron 115 mg

    Sentinel Yellow for Dogs 26-50 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 11.5 mg
    Lufenuron 230 mg

    Sentinel White for Dogs 51-100 lbs:
    Active Ingredient (per tablet) Amount
    Milbemycin Oxime 23 mg
    Lufenuron 460 mg

    Sentinel 4.4 5 582 589
    Does more than other products Besides prevention of HeartWorm, Sentinel also prevents whipworm and some other parasites, which other products don't do, including Heartgard. My dog had WhipWorm once, and after was cured has had no re-occurrance since using Sentinel Regularly. For me it is worth the extra money since, antibiotics for other parasites can add up quickly. Besides the price the only other minor negative for me was my dog won't take the chewable tablet unless it hide it in cheese or meat. He use to eat the Heartgard without hiding it like any other treat. 01/25/2015
    my dogs love this! I used Sentinel for years until it was not available and had to switch to another brand that also needed a flea protectant. No matter which flea protection I used it smelled something horrible and my dogs hid away so I couldn't put it on them. .So glad Sentinel is back. They love the taste, no oils to put on their backs and they no longer hide from it. 01/13/2015
    The product has great features I also use this with my dog, Brutus! It's great having an all in one pill. It's also cheaper, taste great as he eats the pill!! Which is a plus!! I've had issues with the liquid flea and tick, it seems like it burns his skin. I was so happy to find the Sentinel. I would recommend this product!! Thanks. 01/09/2015
    Great product We love using Sentinel for all of our dogs. It has everything including flea prevention so we don't have to purchase another product for that. We have been using it for years and haven't ever had any reactions while our dogs are taking Sentinel. We also have had great experience with 1-800 Pet meds, delivery is prompt and everyone is very pleasant to deal with. 12/25/2014
    Great for Shelties Since they discontinued Interceptor, Sentinel is the next best thing for Shelties or breeds who may not be able to take Ivermectin which is in Heartguard. I sincerely hope this heartworm preventive is not discontinued! 12/22/2014
    2 3 4 5 ... 21 Next
    346 Questions · 641 Answers

    Ask & Answer.

    Talk to other pet lovers about this product.

     
     
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    1 week ago
    by
    Khaleesi'sOwner
    Answer this question

    Answers

    Answer: 
    Thank you for your question. There are six doses per pack.
    1 week ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    2 weeks, 6 days ago
    by
    mrs.knoll
    Houston TX
    Answer this question

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    Answer: 
    there are times when both comfortis and sentinel are used together. The ultimate decision is up
    to your vet since both are prescription items.
    1 week, 6 days ago
    by
    Linda M 1800petmeds pharmacist
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    1 answer

    Fleas

    I have been using Sentinel for awhile now and have noticed my dogs are scratching. I put the flea comb to them and they have a few fleas. Not many but still they scratch. Can I use frontline or something else to rid us of the fleas ?
    3 weeks ago
    by
    jean
    Answer this question

    Answers

    Answer: 
    Be careful, this product only claims to break the flea cycle at the egg stage, it DOES NOT KILL ADULT fleas. The box even says so. So YES will still need another product to keep the adult fleas away or kill them. I still use Frontline, or Advantix for adult fleas. Advantix appears to be one of the few that claim to Repel fleas. The box also says Capstar may be used to kill adult fleas Temporarily, to speed up flea control. When I had another dog that brought fleas into the house I also had to use a Flea Spray around the whole house and carpet to kill the infestation in the house, rugs, corners and areas the dog slept. Be careful with those products and read the directions very carefully.
    User submitted photo
    4 days ago
    by
    Rufus300
    Northern Indiana
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    3 weeks, 5 days ago
    by
    Nancy
    Answer this question

    Answers

    Answer: 
    NO, It doesn't even kill ADULT fleas. It only is for worms and parasites, and only "Breaks" the flea cycle by killing flea Larva and eggs. And it does a great job at that. But you still need to use another Product for Adult fleas, and Ticks. Use the comparison feature on this site. It is great for sorting out what some products do compared to others. I say that because not all flea products handle ticks.
    User submitted photo
    4 days ago
    by
    Rufus300
    Northern Indiana
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    Answer: 
    No. Sentinel does not treat ticks as it does not contain an ingredient that will get rid of this pest. Your best bet is to discuss with your vet what would be the best way to fend off ticks.
    3 weeks, 5 days ago
    by
    Kay
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    I keep my dog on this year round. She got her last monthly dose on 10/9/14. I would like to give it to her on 11/6/14 if it is safe to do so.
    3 months ago
    by
    Anonymous
    Answer this question

    Answers

    Answer: 
    I'm not a vet, but I am pretty sure 3 days early would be fine. After all, February only has 28 days in it, compared to 30 and 31 for the other months.
    User submitted photo
    4 days ago
    by
    Rufus300
    Northern Indiana
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    Answer: 
    Yes, you can do that safely.
    2 months, 4 weeks ago
    by
    Linda M 1800petmeds pharmacist
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    2 3 4 5 ... 13 Next
    2 3 4 5 ... 13 Next
    This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
    Note: Any trademarks are the property of their respective companies.
     
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