Ear Infections
Flea & Tick
Heart Problems
Hot Spots
Shedding Control
Skin Irritation
Tear Stains
Urinary Infections
Weight Management
See All A-Z
Ear Infections
Flea & Tick
Heart Problems
Hot Spots
Shedding Control
Skin Irritation
Tear Stains
Urinary Infections
Weight Management
See All A-Z
Breath Fresheners
Chews & Treats
Rinses & Water Additives
Toothpaste & Toothbrushes
Ear Cleansers
Ear Infection Remedies
Ear Mite Treatments
Antibiotic Anti-Infective
Artificial Tears & Lubricants
Eye Inflammation
Tear Stain Removers
Flea & Tick Prevention
Heartworm & Flea Control
Home Flea & Tick Treatment
Oral Flea Treatments
Pet Flea & Tick Control
Tick & Flea Collars
Canned Pet Food
Dry Pet Food
Raw Pet Food
Adult Pet Food
Glucose Balance
Digestive Health & Support
Grain Free
Joint Support
Kitten Food
Puppy Food
Senior Pet Food
Skin Support
Small Breed Dog Food
Weight Loss & Management
Pet Food Storage
Joint Pain
Joint Supplements
Lifting Harness
Orthopedic Beds
Steps & Ramps for Mobility
Allergy Relief
Compound Medications
Cough Relief
Digestive Health & Enzymes
High Blood Pressure
Hormonal Endocrine
Insulin & Glucose Balance
Motion Sickness & Nausea
Seizure Disorder
Urinary Tract & Kidneys
Bowls & Elevated Feeders
Car Seats & Pet Carriers
Cat Litter
Cesar Millan Training Aids
Crates & Kennels
Drinking Fountains
Elizabethan Collars
First Aid
Furniture Protectors
Grooming Tools
Leashes & Harnesses
Life Jackets
Outdoor Cat Pens
Pet Food Storage
Stain Removers
Steps & Ramps
Training Aids
Wireless Dog Fences
First Aid
Fish Oils & Omega 3
Fly Control
Grooming Tools
Hairball Remedies
Itch Relief
Ringworm Treatments
Shedding Control
Skin Care Supplements
Skin Medications
Digestive Enzymes
Fish Oils & Omega 3
Liver Support
Senior Support
Whole Food Supplements
    Click for Rx info
Monthly topical heartworm and flea prevention in a single application.
  • Prevents heartworm
  • Kills fleas & flea eggs
  • Kills ticks
  • Kills roundworms &
  • Collie/Herding Dogs:
    See cautions below


    Q & A
    Starts at $47.99 Ships in one business day or less
    1_Select a Weight


      Product Info   How to use   Ingredients   Customer Reviews   Q & A  

    What is Revolution?

    Revolution is a safe and simple monthly topical medication used to protect your pet from heartworms, fleas, and ear mites. It also protects dogs from ticks and sarcoptic mange and cats from roundworms and hookworms. Revolution for Dogs and Cats requires a prescription from your veterinarian. (3 Pack = 3 doses which lasts 3 months.)
    Revolution for Dogs and Cats
    Dogs (6 weeks of age or older and no weight requirement)
    Cats (8 weeks of age or older and no weight requirement)
    Protects your pet from heartworms and fleas
    Fights both internal and surface parasitic infections
    Treats Sarcoptic mange in dogs
    Treats and controls ear mites
    Controls American Dog Tick infestation
    Treats and controls roundworms and hookworms in cats
    Only administered once a month
    Safe and easy to use

    How it works:
    Revolution works by penetrating the skin and entering your pet's bloodstream. Concentrations of selamectin, the active ingredient, in the tissue and bloodstream prevent heartworm disease. Selamectin also redistributes into the skin from the bloodstream and kills adult fleas, American dog ticks, and ear mites, and prevents flea eggs from hatching. It is also an anthelmintic, which means it fights to expel parasitic worms. Parasites ingest the drug when they feed on the animal's blood. Revolution is safe for pregnant and lactating pets.

    Side effects are uncommon, with less than 1% of dogs showing signs of digestive upsets. It is not advisable to use Revolution in pets that are ill or underweight. Collies and herding dog breeds may have a reaction to the ingredient selamectin if given over the recommended dosage amount. If your dog is a collie or other herding dog breed and your veterinarian has prescribed Revolution, we urge you to monitor your pet for 8 hours and call your vet if your dog displays any signs of weakness, staggering, dilated pupils, trembling, drooling, or pressing his or her head against a wall.

    More Information:
    Brand Name
    Revolution (Pfizer Animal Health)
    Generic Name
    Selamectin (see-la-mekí-tin)

    What is the most important information I should know about Revolution: Revolution is a prescription medication applied topically once a month. Do not use Revolution on puppies under 6 weeks of age or kittens under 8 weeks of age with no weight requirements. According to the product literature, Revolution is safe for use on pregnant or lactating dogs and cats.

    What is Revolution: Revolution is a topical parasiticide applied once a month for the prevention of heartworm disease in dogs and cats. Revolution is also used on dogs for the treatment or prevention of fleas, the American Dog Tick, ear mites, and canine sarcoptic mange. When used on cats it is also used to treat or prevent fleas, ear mites, hookworms, and roundworms. It is recommended that heartworm prevention be used year-round. Revolution may also be used for purposes other than those listed in this guide.

    What should I discuss with my veterinarian before applying Revolution on my pet: Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

    How should this medication be used: Apply Revolution exactly as directed by your veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. Revolution is available as unit of use applicator tubes containing the specific amount of medication based on the weight of your pet. Revolution is available as a 15mg/0.25ml puppy/kitten dose for puppies older than 6 weeks and kittens older than 8 weeks weighing up to 5 lbs. Revolution is also available for cats 5.1-15 lbs (45mg/0.75ml), 15.1-22 lbs (60mg/1ml), and for dogs 5.1-10 lbs (30mg/0.25ml), dogs 10.1-20 lbs (60mg/0.5ml), 20.1-40 lbs (120mg/1 ml), 40-1-85 lbs (240mg/2 ml) and 85.1-130 lbs (360mg/3ml). For dogs over 130 lbs use the appropriate combination of tubes. The entire contents of the tube should be used. Do not split the contents as the accuracy of the dose and effectiveness of the medication cannot be assured. Bathing or shampooing your pet 2 or more hours after treatment will not reduce the effectiveness of Revolution. Keep this medication away from children and pets. 

    What happens if I miss applying a dose: Give the missed dose as soon as you remember. Do not give a double dose of the medication.

    What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose, while rare, may include salivation and lack of coordination, as well as symptoms listed below as side effects.

    What should I avoid while using Revolution on my pet: Because humans can contract hookworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household and to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended. Do not use on sick, weak, or underweight animals. Do not apply to wet hair. Dogs should be tested for heartworms prior to using Revolution. In humans, Revolution may be irritating to skin and eyes. Wash hands thoroughly after applying Revolution to your pet.

    What are the possible side effects of Revolution: Side effects of Revolution that may occur include temporary hair loss at the site of application, loss of appetite, drooling, vomiting, diarrhea, drowsiness, rapid breathing, increased heart rate, and muscle tremors.

    What other drugs will affect Revolution: Do not apply Revolution to your pet if already giving an alternate heartworm medication. When switching from another heartworm medication, begin Revolution when the next dose of the heartworm medication is due.

    Where can I get more information: Your pharmacist has additional information about Revolution written for health professionals that you may read.


    Revolution is a prescription medication.
    Apply Revolution once a month on the same day of each month year round.
    Use the entire contents of the tube. Do not split the contents since the dose and therefore the effectiveness of the product can be reduced.
    Part your pets hair at the base of the neck between the shoulder blades until you can see the skin, and place the tip of the tube on the skin.
    Apply the contents of the tube to a single spot on the skin at the base of the neck between the shoulder blades.
    Tip: Revolution is quick drying. The pet can be bathed 2 or more hours after applying.
    Pet Weight Dosage
    Puppies: (6 weeks of age or older) Up to 5 lbs Apply contents of 1 tube once a month (Mauve Box)
    Dogs: 5.1-10 lbs Apply contents of 1 tube once a month (Purple Box)
    10.1-20 lbs Apply contents of 1 tube once a month (Brown Box)
    20.1-40 lbs Apply contents of 1 tube once a month (Red Box)
    40.1-85 lbs Apply contents of 1 tube once a month (Teal Box)
    85.1-130 lbs Apply contents of 1 tube once a month (Plum Box)
    Over 130 lbs Use the appropriate combination of tubes
    Kittens: (8 weeks of age or older) Up to 5 lbs Apply contents of 1 tube once a month (Mauve Box)
    Cats: 5.1-15 lbs Apply contents of 1 tube once a month (Blue Box)
    15.1-22 lbs Apply contents of 1 tube once a month (Taupe Box)
    Storage: Should be stored at room temperature.
    Revolution for Puppies/Kittens up to 5 lbs:
    Active Ingredient (per single dose tube) Amount
    Selamectin 15 mg

    Revolution for Cats 5.1-15 lbs:
    Active Ingredient (per single dose tube) Amount
    Selamectin 45 mg

    Revolution for Cats 15.1-22 lbs:
    Active Ingredient (per single dose tube) Amount
    Selamectin 60 mg

    Revolution for Dogs 5.1-10 lbs:
    Active Ingredient (per single dose tube) Amount
    Selamectin 30 mg

    Revolution for Dogs 10.1-20 lbs:
    Active Ingredient (per single dose tube) Amount
    Selamectin 60 mg

    Revolution for Dogs 20.1-40 lbs:
    Active Ingredient (per single dose tube) Amount
    Selamectin 120 mg

    Revolution for Dogs 40.1-85 lbs:
    Active Ingredient (per single dose tube) Amount
    Selamectin 240 mg

    Revolution for Dogs 85.1-130:
    Active Ingredient (per single dose tube) Amount
    Selamectin 360 mg
    Revolution 4.5 5 1558 1572
    Revolution is Perfect! Revolution is the only flea/tick/heartworm medication my vet wants Penny on! I haven't seen any of these parasites since I began using Revolution on my previous dog when it was first on the market, and I would need a really good reason to switch to another product. Penny hates oral meds, so I wouldn't use any of those kinds of meds, and the effectiveness of Revolution makes it hands-down my choice. The fact that it's effective against heart worm as well as fleas and ticks means I can eliminate yet another routine medication. Just a monthly dose of Revolution onto the neck, and we can forget it (I actually go 6 weeks between doses because Penny is mostly an indoor dog). There is only one potential problem using this medication. You can't forget to apply it for a long time (your vet has to define what "a long time" means for your area), and then go back to using it without another vet visit. The reason is that this is a heart worm medication and if your dog gets infected with heart worm while off of Revolution, giving it the medication can actually be fatal for your dog. So use the included stickers on your calendar or date book to remind you to apply it regularly. Finally, you may see this as an inconvenience that Revolution is a prescription medication (no doubt, because of the heart worm preventative in it). Your vet needs to make sure your dog is free of heart worm with a blood test before prescribing. But once that's assured, you can order Revolution from 1-800-PetMEDS and they will handle refill approvals from your vet from then on. As long as your vet knows you've been using Revolution without fail, she'll no doubt approve all requests for the refills without a visit. Go Revolution! 07/27/2014
    Love Revolutions! :) Revolutions keeps both my kitties flea- and everything else-free! :) Nothing's is alive on or in them except them! :) 06/13/2011
    the best I love this product! Easy to use and takes care of everythng. 05/24/2011
    My cat's skin reacted but she is used to it now My cat is an indoor but she spends most of her time in the balcony throughout the summer so the Vet recommended Revelution. She got hairless on the spot I applied it for the first and second time so I stopped using the product for a year. Then I decieded to try it again as she didn't intake any pills for Hearworm. This time I didn't apply it on just one spot between her shoulder blade. I asked the Vet and she suggested me to put the medication on three different spots close to each other around the shoulder blade area which even makes it more effective and sure enough this time she didn't show any skin reaction. I applyied the third applications last month with no problem. Happy 05/23/2011
    I really like this product! This is the best product I've found for fleas. And I like that it's effective for ticks and heartworm as well. In past years, I've used other products, but with much less effectiveness. My vet said it can take several weeks for the other products I've used to build up their effectiveness in the cat's system. Meanwhile, on nice days when we take her outside on a leash, she brought fleas back into the house. They got into the carpet and furniture, and were biting the people in the house too. With Revolution, the fleas were gone within DAYS. And ticks seem to be more prevalent in our area now, thanks to irresponsible people dropping off cats in our rural area. Yet my cat has avoided being a host to them. My own cat has never had any adverse reactions to Revolution, although I understand that it's a possibility for particularly sensitive individuals. I can only suggest that you try it in a limited quantity to see how your cat/dog reacts to it. But in my own opinion, I don't think there's a better product available than Revolution. 03/16/2011
    2 3 4 5 ... 53 Next
    823 Questions · 1,134 Answers

    Ask & Answer.

    Talk to other pet lovers about this product.

    « Back
    what would be the appropriate dosage for a cat weighing 35 lbs. Can a combination of different weight doses be used to achieve results.
    3 days ago
    Answer this question
    I have 2 cats and they tend to lick flea medication off of each other.
    1 week, 4 days ago
    Stonewall, LA
    Answer this question
    My dog fluxuates around 82-87 pounds, should i get the 40-85 dose, or the 85 and up dose?
    User submitted photo
    2 weeks, 6 days ago
    Answer this question


    It depends on the pets history and if the pet tends to be borderline. It is okay to go with the higher dose usually. Ultimately your vet will decide when prescribing.
    2 weeks, 4 days ago
    Kelly P
    Vote as Best Answer
    Thanks for Voting
    This is the first time I've used this product. I have a small dog (pug/jack russel cross). After putting it on him, I noticed his fur is hard in the area and I'm concerned I didn't get it down right to his skin. Should it all have been absorbed in his skin or is having some on his fur normal?
    1 month, 3 weeks ago
    Answer this question


    It is very normal for there to be some of it on the their fur. All of the medicine was absorbed, it is just a dry spot where you put the medicine.
    1 month, 2 weeks ago
    Arlington, WA
    Vote as Best Answer
    Thanks for Voting
    2 3 4 5 ... 29 Next
    2 3 4 5 ... 29 Next
    This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
    Note: Any trademarks are the property of their respective companies.
    Facebook Twitter Pin It
    You May Also Like
    Be Flea Free Shampoo 18oz

    Be Flea Free Shampoo
    Be Flea Free Shampoo 18oz

    Shop Now
    Also For Your Pet

    Kill Roundworms, Hookworms, Whipworms & Tapeworms:



    Tape Worm Tabs:



    Homeopathic Wormer:



    Health and Well Being:



    Your Pet's Dream Den:



    Squeaky Max Toy :


    Help / Customer Service
    My Account
    PetMeds® Sites
    PetMeds® Programs
    Our 100% Guarantee
    About Us
    Contact Us
    PetMeds® Help
    Privacy Policy
    Printable Order Form
    Site Map
    Vet Directory
    Request a Catalog

    Email Preferences
    Easy refill
    Track my order
    My Account Page
    My pet has passed away
    PetMedsģ Blog
    PetHealth 101ģ
    PetMedsģ Charitable Causes
    1-800-PetMedsģ Careers
    PetMeds® Investor Relations
    pet meds
    Pet Meds Photos
    Pet Meds News
    Pet Health Articles
    Affiliate Program
    Shelter & Rescue Program
    Join our Social Network
        PetMeds® on Facebook
        PetMeds® on Twitter
        PetMeds® on YouTube
        PetMeds® Google+
        PetMeds® LinkedIn
    Copyright © 2014 PetMed Express, Inc. All Rights Reserved.
 has earned Veterinary-Verified Internet Pharmacy Practice Sites(CM) (Vet-VIPPS(CM)) accreditation through the National Association of Boards of Pharmacy® (NABP®).
    Verisign Secured Click for the BBB Business Review of this Pharmacies in Pompano Beach FL