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Profender Cat Wormer

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  Product Info   How to use   Ingredients   Customer Reviews   Q & A  
What is Profender?
Profender is the first-ever, topical dewormer used to treat and control intestinal parasites in cats, such as hookworms, tapeworms and roundworms. Not only is Profender easy to use, safe and effective, it also works in a single-dose capacity so there is no need for that pesky second dose! Profender requires a prescription from your veterinarian.
For: Cats (8 weeks of age or older)
Kills hookworms, tapeworms and roundworms
Fast-acting, powerful topical treatment
One-time application
Safe and effective

How it works:
Profender works by using the time-tested active ingredient praziquantel and a unique compound called emodepside to eradicate intestinal parasites. Once Profender encounters your cat's skin, it rapidly enters the bloodstream and travels to the intestines, controlling and eliminating unwanted parasites.

Not for use on kittens under 8 weeks old or those under 2.2 lbs. and safe use in breeding, pregnant, or lactating pets has not been determined. Use with caution in sick or debilitated cats. Keep out of reach of children, and to prevent accidental ingestion of the product, children should not come in contact with the application site for 24 hours while the product is being absorbed. Pregnant women or women who may become pregnant should avoid direct contact with, or wear disposable gloves when applying this product.

Profender for Cats

More Information:
Brand Name
Profender (Bayer)
Generic Name
emodepside + praziquantel
What is the most important information I should know about Profender: Profender is a prescription-required topical solution that is FDA-approved for the treatment and control of hookworm, roundworm, and tapeworm infections in cats 8 weeks of age and older and weighing at least 2.2 lbs. Profender is packaged in single unit dosing applicator tubes and is available as 0.35 ml tubes containing emodepside 7.5 mg and praziquantel 30 mg for use on cats 2.2-5.5 lbs, 0.70 ml tubes containing emodepside 15 mg and praziquantel 60.1 mg for use on cats 5.6-11 lbs, and 1.12 ml tubes containing emodepside 24 mg and praziquantel 96.1 mg for use on cats 11.1-17.6 lbs. For cats over 17.6 lbs, the appropriate combination of tubes should be used.

What is Profender: Profender contains a combination of insecticides (emodepside and praziquantel) and is used for the treatment and control of hookworm, roundworm, and tapeworm infections in cats.

What should I discuss with my veterinarian before applying Profender: Tell your veterinarian if your pet is breeding, pregnant or lactating since safe use of this product has not been determined in such pets. Do not use in animals allergic to Profender or to either of the individual ingredients emodepside or praziquantel (Droncit, Tape Worm Tabs).

How should this medication be used: Profender is applied topically to the skin. It is not given by mouth. Do not apply to broken skin or if the hair coat is wet. Follow the manufacturer's directions for application. A single treatment is effective and a second treatment should not be necessary. If re-infection occurs, the product can be re-applied after 30 days. If you do not understand the directions, or if you have difficulty applying the medication, contact your pharmacist or veterinarian. Store Profender at or below 77ļ F.

What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include increased salivation, tremors, or drowsiness.

What should I avoid when applying Profender: Always follow the dosage instructions provided by your veterinarian. If you do not understand these instructions ask your veterinarian or pharmacist to explain them to you. Do not use in cats under 8 weeks of age or less than 2.2 lbs. Do not use on cats that are sick, debilitated, or underweight. Do not allow any animal to lick the application site for 24 hours. Separation of treated animals may be necessary. Children should not come in contact with the application site for 24 hours after application. Pregnant women, or women who may become pregnant, should avoid direct contact with, or wear disposable gloves when applying this product. In humans, Profender can cause skin or eye irritation and may be harmful if swallowed. Wash hands thoroughly with soap and water after handling. In case of accidental ingestion or if skin or eye irritation occurs, call a poison control center or physician for treatment advice.

What are the possible side effects of Profender: Side effects that may occur include licking/excessive grooming, scratching at treatment site, salivation, lethargy, alopecia (loss of hair), agitation/nervousness, vomiting, diarrhea, eye irritation, respiratory irritation, and shaking/tremors. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What other drugs will affect Profender: Talk to your veterinarian or pharmacist regarding any other medications, including vitamins and supplements, and other flea and tick products your pet is using.

Where can I get more information: Your pharmacist has additional information about Profender for Cats written by health professionals that you may read.

Profender is a prescription topical medication for the treatment and control of hookworm, roundworm, and tapeworm infections in cats and kittens.
Apply only once to your pet's skin and use the entire contents for one application.
Twist cap off the appropriate tube of Profender based on your cat's weight and part your pet's hair at the base of the neck until your cat's skin is visible (be sure your cat's skin is dry).
Place the tip of the tube on the exposed skin and squeeze entire contents directly onto your cat's skin. Lift tube away from the skin before releasing pressure on the tube.
Tip: Do not allow any animal to lick the application site for one hour after application, and make sure not to get the product in your cat's mouth or eyes. In houses with multiple pets, separation of treated animals may be necessary.
Pet Weight Dosage
(8 weeks of age or older)
2.2-5.5 lbs Apply contents of 1 tube once (Green box)
5.6-11 lbs Apply contents of 1 tube once (Orange box)
11.1-17.6 lbs Apply contents of 1 tube once (Purple box)
Over 17.6 lbs Treat with the appropriate combination of tubes
Storage: Store at room temperature 15- 30C (59- 86F).
Profender for Kittens 2.2-5.5 lbs (Green box):
Active Ingredient (per single dose .35 mL tube)                            Amount
Praziquantel 30 mg
Emodepside 7.5 mg

Profender for Cats 5.6-11 lbs (Orange box):
Active Ingredient (per single dose .70 mL tube)                            Amount
Praziquantel 60.1 mg
Emodepside 15 mg

Profender for Cats 11.1-17.6 lbs (Purple box):
Active Ingredient (per single dose 1.12 mL tube) Amount
Praziquantel 96.1 mg
Emodepside 24 mg
Profender Cat Wormer 3.6 5 17 17
Worked For Me 24 hours after treatment, I saw dead roundworms in my cat's "end-product". No more worms seen since. No adverse reactions from my cat. Gave treatment to all inside cats (4 total) since they use same litter box. No adverse reactions from the other cats. Vet tech said one treatment per year should be given to cats. So, from now on I will do this once per year. Very satisfied with this treatment. 01/24/2014
THE BEST STUFF EVER!!! I used this on an outside cat that had the worst case of worms I'd ever seen. 2 days after application all the worms were gone!!! I'm recommending this to everyone!!! 12/18/2013
This product didn't work I recently adopted a rescue kitten that had a lot of problems to begin with. He was infested with fleas and we combed all of them off of him before we even took him inside our house. We found three more fleas on him the first two days that he had been inside the house. I have washed his beds and blankets regularly since then, just to be on the safe side. We treated him with Advantage II as soon as we got the fleas off of him and have seen absolutely no more signs of fleas since those last three (which was over a month ago). Well a little over a week ago we found the live and dried up tapeworm segments on his rear end. The vet prescribed Profender for the tapeworm and after a few days I was still finding the live and dried up segments. I called the vet again and they said it could take up to a week for it all to pass, depending on how long the tapeworm was. Well today it has been almost 10 days since he was treated and I'm still finding live segments today. I called the vet yet again and they blamed it on "the environment" in my house saying that he got re-infected from fleas. That is a load of bull because there have been no signs of fleas on him since we treated him over a month ago (he has even had the second treatment of Advantage II this month as well). Our other adult cat has never had fleas and doesn't have tapeworm either. Now the vet is prescribing another de-wormer that is an oral treatment. I would strongly suggest not even bothering with Profender because I strongly believe it didn't even work in the first place and that he didn't get re-infected. He is still infected with the one that Profender didn't get rid of!! I strongly suggest not using Profender after my experience! I know that my house doesn't have fleas because I have been in a house that has had them, and you find them all over the pets, all over the house, and on the people as well. This is not the case for me. As I said before I wash his bedding and our bedding regularly and I vacuum regularly. I think my adult cat would be showing signs of fleas or tapeworm too if my kitten was being re-infected!! 12/16/2013
Unexpected consequences We adopted two male cats - one 14 lbs and one 7 lbs. - and they tolerated the application pretty well. Got this from the vet as she did not have any Drontal at the time. The smell is not as overpowering as some topical flea treatments. The amount of liquid packaged for large cats is a lot so even though you apply it to a small area, the ensuing scratching spreads it into an area on the body that could be reached by the cat's tongue. The parasite positive cat already had loose bowels before the treatment but fair warning, this stuff gave both cats projectile pooping! I'm sure by the time the drug has run its course, things down South should normalize (crossing fingers). Until then, keep a disinfecting rag handy :) For the cost, I would rather chance pilling the cats with Drontal. 11/01/2013
Stress free?? They advertise this product as being a stress free way of de-worming your cat as opposed to the tablet variety. Stress free in whose opinion? I found the whole process to be very stressful. My cat absolutely hated the drops going on and ran around like crazy trying to get it off. There is the worry that your cat will ingest the stuff as contrary to popular veterinary belief, a cat can groom the back of it's neck. It must really irritate as well as she wouldn't stop grooming and scratching the area and was unhappy about us touching her there. The next day she was lethargic and quiet, so one wonders what the heck we are doing to our pet by forcing these poisons into them. Okay, the worms have to go, but unless you are absolutely certain that your cat has worms or if you have just picked her up from a shelter, routine de-worming is to be avoided. Does it work though? I don't know and it is very hard to ascertain. 10/11/2013
27 Questions · 35 Answers

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1 answer


how long after applying profender do worms and/or eggs disappear? i gave my three cats profender and kept them in their room while i sprayed and vacuumed entire house for fleas and eggs. i don't want them to come back out while they are still infected and start the cycle again.
3 months, 3 weeks ago
New York
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Profender rapidly enters the bloodstream and travels to the intestines, controlling and eliminating unwanted parasites. A single treatment is effective and a second treatment is not usually necessary. It can be re-applied after 30 days if re-infection occurs.
3 months, 2 weeks ago
Lisa M
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Profender Worm Med.
7 months ago
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Safety has not been determined. You will have to ask your vet.
7 months ago
Linda M 1800petmeds pharmacist
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I put this on one of my cats but he of course is able to lick part of the area behind his head. I am sure he was able to lick some of it because he has had diareaha. Should I have any other concerns?
1 year ago
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Probably not. Even when put well above the cat's shoulders, subsequent scratching of the area will spread the liquid into a reachable area for ingestion. Unless your cat LIKES the taste, a small amount of ingestion will produce temporary side effects. After all, the drug is designed to get into the digestive system via blood circulation. As always, read package info.
1 year ago
Clarkesville, GA
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1 year ago
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just received my order today and only one tube.
5 months ago
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Thank you for your question. There is one tube in each box.
1 year ago
Maureen PetMeds Pro
Pompano Beach, FL
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This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
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