What is Phenylzone Paste?

Benefits:
•	Relieves pain and inflammation
•	Particularly good for osteoarthritis
•	Reduces fever

How it works:
Phenylzone Paste is a non-steroidal anti-inflammatory drug (NSAID) which through its anti-inflammatory action can relieve pain, reduce inflammation and reduce fever.

Cautions:
Do not use in pregnant or lactating mares. Do not give phenylbutazone with other NSAIDs, corticosteroids, or other ulcer-causing medications.

What is the most important information I should know about Phenylzone Paste: Phenylzone Paste is a prescription medication FDA approved for use in horses. It is available by prescription as a 12 Gm oral syringe. The usual dose in horses is 1 or 2 Gm per 500 pounds, but not to exceed 4 Gm daily. Doses should be reduced after the first 48 hours of treatment to the lowest dose that gives the desired effect. Phenylzone Paste should be given with food. Phenylzone Paste should not be given to animals that are dehydrated or have stomach ulcers; anemia or bleeding disorders; liver, kidney or heart disease.

What is Phenylzone Paste: Phenylzone Paste is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with the musculoskeletal system in horses. Phenylzone Paste may be used for purposes other than those listed in this medication guide.

What should I discuss with my veterinarian before giving Phenylzone Paste to my horse: Tell your veterinarian if your horse has ever had an allergic reaction to Phenylzone Paste or any other NSAID. Tell your veterinarian if your horse has any liver, kidney or heart disease. Tell your veterinarian if your horse is pregnant or lactating.

How should this medication be given: Give this medication exactly as directed by your veterinarian. If you do not understand the directions, ask your pharmacist or veterinarian to explain them to you. Phenylzone Paste should be given with food. Store this medication at room temperature. Keep out of the reach of children and pets.

What happens if I miss giving a dose: Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication.

What happens if I overdose the horse: In the event of overdose, contact your veterinarian or veterinary emergency room. Symptoms of overdose may include decreased urine production and blood in the urine; jaundice (yellowing of the skin, gums and eyes); pale gums, weakness, and ulcers.

What should I avoid while giving Phenylzone Paste to my horse: Do not use Phenylzone Paste in animals allergic to it or other NSAIDs. Do not use in pregnant or lactating mares. Do not give Phenylzone Paste with other NSAIDs, corticosteroids, or other ulcer causing medications.

What are the possible side effects of Phenylzone Paste: Side effects that may occur when using Phenylzone Paste may include ulcers, kidney damage, bloody stool, decreased white blood cells and platelets as well as an allergic reaction (facial swelling, hives, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, coma). Stop the medication at the first sign of gastrointestinal upset, or jaundice. Authenticated cases of Agranulocytosis associated with the drug have occurred in man. Fatal reactions, although rare, have been reported in dogs after long term therapy. Routine blood counts should be conducted at weekly intervals at the beginning of therapy and at 2 week intervals thereafter. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

What other drugs will affect Phenylzone Paste: Use caution when giving Phenylzone Paste with phenytoin, warfarin, sulfonamides, glipizide, digoxin, barbiturates, rifampin, chlorpheniramine or diphenhydramine. Talk to your veterinarian or pharmacist before using Phenylzone Paste with any prescription or over the counter medications, including vitamins, minerals and herbal supplements.

Where can I get more information: Your pharmacist has additional information about Phenylzone Paste written for health professionals that you may read.