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Frontline Plus

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Frontline Plus?

Frontline Plus is a monthly topical flea and tick preventative for dogs and cats. Frontline Plus kills 100% of adult fleas on your pet within 12 hours and 100% of all ticks and chewing lice within 48 hours. Frontline Plus contains an insect growth regulator, S-methoprene, which kills flea eggs and larvae. It's effective against all stages of the brown dog tick, the American dog tick, the lone star tick and the deer tick (the major carrier of Lyme disease). (3 Pack = 3 doses which lasts 3 months.)

For:

Cats/Kittens and Dogs/Puppies (8 weeks of age and older)

Benefits:
  • Kills all existing fleas on your pet within 12 hours
  • Each application provides a full month of protection
  • Also aids in the control of sarcoptic mange infections in dogs
  • Great for pets that swim since it's waterproof
  • Kills ticks and chewing lice
How it Works:

Frontline Plus contains fipronil, a broad-spectrum insecticide and slow-acting poison that disrupts the central nervous system of fleas and ticks and S-Methoprene, an insect growth regulator that kills flea eggs and larvae. The active ingredients are stored in the sebaceous glands and are wicked out of the hair follicles and continuously re-applied to the coat for long-lasting, waterproof protection.

Cautions:

Your pet may experience some temporary irritation at the site of application. If signs persist or become severe within a few days of application, consult your veterinarian immediately.

Brand Name:

Frontline Plus (Merial)

Generic Name:

Fipronil, S-methoprene

What is Frontline Plus used for:

Frontline Plus provides convenient and effective flea and tick control in dogs and cats, puppies and kittens. It is effective against all stages of the brown dog tick, the American dog tick, lone star tick and deer ticks (the major carrier of Lyme disease). It also kills flea eggs and flea larvae. Frontline Plus rapidly eliminates infestations with chewing lice. Frontline Plus for Dogs and Puppies also aids in the control of sarcoptic mange infections.

Availability of Frontline Plus:

Frontline Plus is a non-prescription (OTC) product.

How Frontline Plus should be used:

Use Frontline Plus for Dogs (fipronil 9.8% and S-methoprene 8.8%) on dogs and puppies 8 weeks or older. Frontline Plus for Dogs is available as 0.67 ml applicators for use on dogs and puppies up to 22 lbs, 1.34 ml applicators for dogs 23-44 lbs, 2.68 ml applicators for dogs 45-88 lbs and 4.02 ml applicators for dogs 89-132 lbs. Wait 24 hours to fully dry before swimming or bathing. Do not reapply for 30 days. Use Frontline Plus for Cats (fipronil 9.8% and S-methoprene 11.8%), available as 0.5 ml applicators, on cats and kittens 8 weeks or older. Place the applicator tip through the animal's hair to the skin level between the shoulder blades. Apply the entire contents of the applicator in a single spot to the animal's skin. Use only one applicator per treatment.

What are the side effects of Frontline Plus:

Pets may experience some temporary irritation at the site of product application. If signs persist or become more severe within a few days of application, consult a veterinarian immediately.

What special precautions are there for Frontline Plus:

This product is for external use on dogs and puppies, cats and kittens 8 weeks or older. Frontline Plus is approved for use on breeding, pregnant, or nursing animals. Consult a veterinarian before using on medicated animals, animals using this product with other pesticides, and debilitated, or aged animals. This product is flammable. Keep away from heat and open flame. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have patient sip water do not induce vomiting unless advised to and patient is conscious. This product can cause eye injury. Flush eyes with plenty of water. Call a physician if irritation persists. Avoid contact with skin, eyes or clothing. Wash thoroughly with soap and water after handling.

In the event of a Frontline Plus overdose:

Contact your veterinarian or veterinary emergency room.

How should I store Frontline Plus:

Store this product at room temperature. Store in the original container only. To dispose wrap original container in several layers of newspaper and discard in trash. Keep out of the reach of children and pets.

How to Use
Directions:
  • Remove the Frontline Plus applicator from the child-resistant package. You can use scissors to snip the foil, or pull the tab to remove the applicator.
  • Snap open the tip of the Frontline applicator - away from your body and face.
  • Part your pet's hair between the shoulder blades until you can see the skin, and place the tip of the applicator on the skin.
Tip:

Wait until application site is fully dry (usually 24 hours) before bathing your pet or letting your pet go swimming.

Dosage:
Dogs/Puppies: (8 weeks of age or older)
Weight
Dosage
Up to 22 lbs
Apply contents of 1 applicator once a month (0.67 ml)
23-44 lbs
Apply contents of 1 applicator once a month (1.34 ml)
45-88 lbs
Apply contents of 1 applicator once a month (2.68 ml)
89-132 lbs
Apply contents of 1 applicator once a month (4.02 ml)
Cats/Kittens: (8 weeks of age or older)
Weight
Dosage
All weights
Apply contents of 1 applicator once a month (0.5 ml)
Horses:
Do not use!
Storage:

Should be stored at room temperature.

Ingredients
Frontline Plus for Dogs & Puppies 8 weeks or older and up to 22lbs:
Active ingredients (per 0.67 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 23-44 lbs:
Active ingredients (per 1.34 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 45-88 lbs:
Active ingredients (per 2.68 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 89-132 lbs:
Active ingredients (per 4.02 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Cats & Kittens 8 weeks or older:
Active ingredients (per 0.50 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
11.8%
Customer Reviews
Frontline Plus is rated 3.4330708661417324 out of 5 by 3,937.
Rated 1 out of 5 by from Waste of Money Bought this product 1 month ago and now after applying a 2nd dose my dog's condition is worse....do not waste your money..totally ineffective
Date published: 2016-09-23
Rated 1 out of 5 by from waste of money I put this medication on both my daschund and Chihuahua. The fleas never seemed to dissipate and both pups required daily bathing to get rid of the fleas this product did not seem to touch
Date published: 2016-09-16
Rated 1 out of 5 by from I think it actually ATTRACTS fleas I applied this to my two cats, and during the summer (and beyond), they did nothing but scratch...and fleas are EVERYWHERE. I would recommend not purchasing this.
Date published: 2016-09-14
Rated 1 out of 5 by from Ineffective for our cats. I seem to remember when Frontline was effective. Two years ago I realized it was a waste of money. Advantage II works. Maybe fleas that were immune to Frontline survived and became the dominant cat pest.
Date published: 2016-09-07
Rated 1 out of 5 by from Don't waste your money! My 5 month old Saint Bernard was spending most of his day biting at his skin and it was terrible to see him this way so I went and bought frontline plus because apparently it's one of the "reliable" brands. Boy was that a mistake. For about 3 days following the treatment, he seemed tick free, but about a week later he was infested with fleas. It got so bad his fur started to fall of (didn't happen before). I eventually took him to the vet where they gave him Nexguard which has worked very well. I recommend that product instead!
Date published: 2016-08-16
Rated 5 out of 5 by from #1 Flea Protection Choice I've heard that you're supposed to switch up your flea protection once in a while to prevent the fleas from getting immune to the same stuff. I once switched to K 9 Advantix and always end up coming back to Frontline. I have never found 1 flea on my dogs after using this.
Date published: 2016-08-12
Rated 1 out of 5 by from DOES NOT WORK! I would give negative stars if I could. Worthless product.
Date published: 2016-08-12
Rated 1 out of 5 by from Bought this product last year and did not work, thought maybe it was a bad batch so tried this summer again and still didn't work, worse product ever, do not waste your money, using Advantage ll now
Date published: 2016-08-11
  • 2016-09-27T06:02CST
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Q&A

How long until the product expires?

Asked by: Suzannes67
The Frontline Plus does not expire.
Answered by: Cherley Petmeds Pro
Date published: 2016-08-31

If the first dose doesn't help how soon can I use it again?

Asked by: myrtle beach
As long as it has been at least two weeks, it is safe to apply another dose.
Answered by: Cherley Petmeds Pro
Date published: 2016-08-31

Do I need a vet or can I apply myself?

Asked by: Feki
You do not need a vet. You can apply yourself, however check with your vet if your pet is on any other medications.
Answered by: paulpharmacistintern
Date published: 2016-08-09

First off, I love this product and used it on my cats for many years. Now i have a kitten and a question! Is it OK to use this on a kitten if the kitten has already been given an oral anti-flea pill? Do I need to wait until 30 days has passed?

Asked by: librarianalex
It could depend on the prior medication. Please check with your veterinarian to make sure when you can start the Frontline Plus on your kitten.
Answered by: paulpharmacistintern
Date published: 2016-08-03

My puppy is 9 weeks old but only weighs 4 pounds. Can I still use the 5 to 22 pound frontline plus on her or wait until she's 5 pounds? 

Asked by: Bharrison
Unfortunately, we are unable to recommend applying the 5-22 lbs dose on a 4 lbs dog. You will have to wait until your furry baby is at least 5 lbs or purchase something that is safe for your furry baby's weight range.
Answered by: Cherley Petmeds Pro
Date published: 2016-08-03

My small dog was damp from a bath when my husband applied Frontline. 24 hrs later fleas are still crawling all over the poor baby. Help.

Asked by: Sheri
You may want to re-dose your furry baby. It is recommended to apply the Frontline Plus 24-48 hours before or after you bathe your furry baby.
Answered by: Cherley Petmeds Pro
Date published: 2016-08-03

I have some Frontline plus for a dog 4-22 lbs can I use it on my 10 lb cat?

Asked by: Nacole
Hi there, No you cannot use this on your cat. You can only use the frontline plus for cats.
Answered by: James PetMeds Pro
Date published: 2016-07-20

I have a 15 pound dog that I applied Frontline plus on three weeks ago, 24 hours after application I gave him a bath. I have been noticing a lot of fleas on him and he is scratching a lot. Can I apply another dose one week before, or will this harm him

Asked by: Beck
Hi there, You need to wait a minimum of 3 weeks to reapply the medication unless your vet tells you you can apply it earlier. In the future, its 24 hours that your pet can come in contact with water after applying the frontline or you would need to wait 48 hours when washing the pet with any soap, shampoo etc.
Answered by: James PetMeds Pro
Date published: 2016-07-20
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