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Frontline Plus (Click for Larger Image)
Prevention that kills fleas within 12 hours/ticks within 48 hours
 
  • Kills Fleas
  • Kills Flea Eggs
  • Kills Flea Larvae
  • Kills Ticks
  • Kills Lice
  • Waterproof
  •  
     
     

    Frontline Plus

     
    Q & A
    Ships in one business day or less
    1_Select a Supply
     
    With 10% OFF Coupon
     
    With 10% OFF Coupon
     
    With 10% OFF Coupon
       
    2_Select your Pet's Weight
      Dogs:




      Cats:

     
    3_Enter a Quantity

     
     
     
      Product Info   How to use   Ingredients   Customer Reviews   Q & A  

    What is Frontline Plus?

    Frontline Plus is a monthly topical flea and tick preventative for dogs and cats. Frontline Plus kills 100% of adult fleas on your pet within 12 hours and 100% of all ticks and chewing lice within 48 hours. Frontline Plus contains an insect growth regulator, S-methoprene, which kills flea eggs and larvae. It’s effective against all stages of the brown dog tick, the American dog tick, the lone star tick and the deer tick (the major carrier of Lyme disease). (3 Pack = 3 doses which lasts 3 months.)
    Frontline Plus for Dogs and Cats
    For: Cats/Kittens and Dogs/Puppies (8 weeks of age and older)
     
    Benefits:
    Kills all existing fleas on your pet within 12 hours
    Each application provides a full month of protection
    Also aids in the control of sarcoptic mange infections
    Great for pets that swim since it's waterproof
    Kills ticks and chewing lice

    How it works:
    Frontline Plus contains fipronil, a broad-spectrum insecticide and slow-acting poison that disrupts the central nervous system of fleas and ticks and S-Methoprene, an insect growth regulator that kills flea eggs and larvae. The active ingredients are stored in the sebaceous glands and are wicked out of the hair follicles and continuously re-applied to the coat for long-lasting, waterproof protection.

    Cautions:
    Your pet may experience some temporary irritation at the site of application. If signs persist or become more severe within a few days of application, consult your veterinarian immediately.


    More Information:
    Brand Name
    Frontline Plus (Merial)
    Generic Name
    Fipronil, S-methoprene

    What is Frontline Plus used for: Frontline Plus provides convenient and effective flea and tick control in dogs and cats, puppies and kittens. It is effective against all stages of the brown dog tick, the American dog tick, lone star tick and deer ticks (the major carrier of Lyme disease). It also kills flea eggs and flea larvae. Frontline Plus rapidly eliminates infestations with chewing lice. Frontline Plus for Dogs and Puppies also aids in the control of sarcoptic mange infections.

    Availability of Frontline Plus: Frontline Plus is a non-prescription (OTC) product.

    How Frontline Plus should be used:
    Use Frontline Plus for Dogs (fipronil 9.8% and S-methoprene 8.8%) on dogs and puppies 8 weeks or older. Frontline Plus for Dogs is available as 0.67 ml applicators for use on dogs and puppies up to 22 lbs, 1.34 ml applicators for dogs 23-44 lbs, 2.68 ml applicators for dogs 45-88 lbs and 4.02 ml applicators for dogs 89-132 lbs. Wait 24 hours to fully dry before swimming or bathing. Do not reapply for 30 days.

    Use Frontline Plus for Cats (fipronil 9.8% and S-methoprene 11.8%), available as 0.5 ml applicators, on cats and kittens 8 weeks or older.

    Place the applicator tip through the animal's hair to the skin level between the shoulder blades. Apply the entire contents of the applicator in a single spot to the animal's skin. Use only one applicator per treatment.

    What are the side effects of Frontline Plus: Pets may experience some temporary irritation at the site of product application. If signs persist or become more severe within a few days of application, consult a veterinarian immediately.

    What special precautions are there for Frontline Plus: This product is for external use on dogs and puppies, cats and kittens 8 weeks or older. Frontline Plus is approved for use on breeding, pregnant, or nursing animals. Consult a veterinarian before using on medicated animals, animals using this product with other pesticides, and debilitated, or aged animals . This product is flammable. Keep away from heat and open flame. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have patient sip water do not induce vomiting unless advised to and patient is conscious. This product can cause eye injury. Flush eyes with plenty of water. Call a physician if irritation persists. Avoid contact with skin, eyes or clothing. Wash thoroughly with soap and water after handling.

    In the event of a Frontline Plus overdose: Contact your veterinarian or veterinary emergency room.

    How should I store Frontline Plus: Store this product at room temperature. Store in the original container only. To dispose wrap original container in several layers of newspaper and discard in trash. Keep out of the reach of children and pets.

     

    Directions:
    Remove Frontline applicator from package Snap open Frontline applicator tip Apply Frontline to pet's skin
    1.) Remove the Frontline applicator from the child-resistant package. You can use scissors to snip the foil, or pull the tab to remove the applicator. 2.) Snap open the tip of the Frontline applicator - away from your body and face. 3.) Part your pets hair between the shoulder blades until you can see the skin, and place the tip of the applicator on the skin.
    Tip: Wait until application site is fully dry (usually 24 hours) before bathing your pet or letting your pet go swimming.
    Dosage:
    Pet Weight Dosage
    Dogs/Puppies:
    (8 weeks of age or older)
    Up to 22 lbs
    Apply contents of 1 applicator once a month (0.67 ml)
      23-44 lbs Apply contents of 1 applicator once a month (1.34 ml)
      45-88 lbs Apply contents of 1 applicator once a month (2.68 ml)
      89-132 lbs Apply contents of 1 applicator once a month (4.02 ml)
    Cats/Kittens:
    (8 weeks of age or older)
    All weights Apply contents of 1 applicator once a month
    (0.5 ml)
    Horses:
    Storage: Should be stored at room temperature.
    Frontline Plus for Dogs & Puppies 8 weeks or older and up to 22lbs:
    Active ingredients (per 0.67 ml applicator) Amount
    Fipronil 9.8%
    (S)-methoprene 8.8%

    Frontline Plus for Dogs 23-44 lbs:
    Active ingredients (per 1.34 ml applicator) Amount
    Fipronil 9.8%
    (S)-methoprene 8.8%

    Frontline Plus for Dogs 45-88 lbs:
    Active ingredients (per 2.68 ml applicator) Amount
    Fipronil 9.8%
    (S)-methoprene 8.8%

    Frontline Plus for Dogs 89-132 lbs:
    Active ingredients (per 4.02 ml applicator) Amount
    Fipronil 9.8%
    (S)-methoprene 8.8%

    Frontline Plus for Cats & Kittens 8 weeks or older:
    Active ingredients (per 0.50 ml applicator) Amount
    Fipronil 9.8%
    (S)-methoprene 11.8%

    Frontline Plus 3.4 5 3613 3661
    The name says it all Kash, our Bichon Frise just turned 3 years of age in March. Has never had a flea or tick. However, with all the warnings about ticks and fleas this year we decided to take heed. We put on a flea/tick collar first of March. I didn't like the sticky collar, the feel, the looks, etc. Kash didn't like it either. I went on line to 1-800-PetMeds and ordered Frontline Plus. Prompt shipping time, and good price. Price-wise, much less than buying at local PetSmart. Upon arrival, immediately followed simple instructiions. So easy to use. I'm a happy customer, Kash is quite content. We will continue to use Frontline Plus, for a healthy and happy dog. No fleas, no ticks. Love the little calendar stickers too, to remind us of next dose. 04/16/2014
    I tried a cheaper product, (even though I was using Frontline ) and boy did I regret that!!! Frontlineis a great product!!! When I used the cheaper product I was bombarded with fleas. It took only to applications of Frontline to get them back under control. Thank you 04/13/2014
    Great!! I recieved my order quickly and everything was there. Great place to do business with. My order came with directions on how to use and it makes life easier just to have it delivered to the door. I recommend this company highly. 04/13/2014
    5* I have used frontline faithfully for years now and never had a issue and NO FLEAS, thanx. 04/12/2014
    We have used this product for years on all 5 of our golden retrievers ... they have never had any fleas and minimal tics over the years- because we are in a tic infested area in new England- we always need to keep watch. Sorry for those that did not have good results-but harsh to say throwing money away- like humans why does Advil work for some and not others.. my vet of 25 years highly recommends but DOES say after every 6-7 doses switch to K9 advan for a few doses as the tics can become accustom to the ingredients. We have not had to do this as of yet.. 04/12/2014
    2 3 4 5 ... 122 Next
    1,272 Questions · 1,809 Answers

    Ask & Answer.

    Talk to other pet lovers about this product.

     
     
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    2 months, 3 weeks ago
    by
    pinky985
    Nevada
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    Answer: 
    Thank you for your question. Please consult your medical professional in regards to this.
    2 months, 3 weeks ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    I have purchased frontline plus for small dogs and cats from maaf and was told that bootleg frontline products have an expiration date on them when the real product does not is this true thanks
    2 months, 3 weeks ago
    by
    Anonymous
    pennsylvania
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    Answer: 
    Thank you for your question. Frontline Plus does not have an expriration date.
    2 months, 3 weeks ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    3 months, 1 week ago
    by
    curious shopper
    Hinton, Wv.
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    Answer: 
    Thank you for your question. The 3 pack includes 3 doses given once a month.
    3 months, 1 week ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    3 months, 3 weeks ago
    by
    Pat
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    Answer: 
    Thank you for your question. Frontline Plus is manufactured in France.
    3 months, 3 weeks ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    3 months, 4 weeks ago
    by
    annie
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    Answer: 
    Thank you for your question. Frontline Tritak repels fleas and ticks but does not kill or repel mosquitos like Frontline Plus does.
    3 months, 4 weeks ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    I did a treatment on my cat, it has been a week and she still has fleas, can i do another treatment
    4 months ago
    by
    Deb
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    Answer: 
    Thank you for your question. We do not recommend you use a treatment so soon, you will have to wait until the second week. We also suggest you try switching to Advantage II as pets are becoming immune to certain medications after a period of use.
    4 months ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    5 months ago
    by
    Anonymous
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    Answer: 
    Frontline Plus is an over-the-counter product, you may notice some irritation at the application site that should resolve in a couple of days. If irritation becomes worse and dose not resolve, take your pet to be examined by the veterinarian. Speak with your pet's veterinarian to choose the best flea/tick prevention for your pet.
    4 months, 4 weeks ago
    by
    Phamacist Intern
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    5 months ago
    by
    kitty
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    Answer: 
    Thank you for your question. Yes, it is possible that the cat and fleas can become immune to the treatments after using the product for an extended period of time.
    5 months ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    Answer: 
    No, I have used Frontline Plus, for years, on each of my full-time cats. I'm still using it on them.
    5 months ago
    by
    Sue
    Addison, NY
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    5 months, 4 weeks ago
    by
    Piper
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    Answer: 
    We moved to the next weight class and it still DID NOT WORK!
    5 months, 2 weeks ago
    by
    Dan0849
    Hamilton, NJ
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    Answer: 
    Thank you for your question. You would want to purchase the correct weight range for your dog. If you use a higher dose then it could result in an overdose.
    5 months, 3 weeks ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    6 months ago
    by
    Mary
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    Answer: 
    You should wait a minimum of 48 hours to apply any topical flea product after you bathe your pet. Bathing your pet removes the necessary oils to spread the medication throughout the skin and to the hairs.
    5 months, 1 week ago
    by
    jennytay
    1
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    Answer: 
    It is recommended that you wait 24-48 hours before applying the Frontline Plus after a bath is given.
    6 months ago
    by
    Maureen PetMeds Pro
    Pompano Beach, FL
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    6 months ago
    by
    ntorch
    Berks County PA
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    Answer: 
    Yes it is necessary to use Frontline in the winter since fleas can live in carpet and would re-infest your pet worse than in the summer.
    5 months ago
    by
    Barney
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    Answer: 
    It is recommended to use Frontline once a month year-round. Fleas can survive in your warm house even during winter months.
    6 months ago
    by
    Pharmacy Intern
    Pompano beach
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    6 months ago
    by
    Reese
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    Answer: 
    No, there are not 9 doses in a 3 pack.

    A 3 pack of Frontline is a 3 month supply if you are only treating one pet. There are 3 treatment vials in one box. Each vile is to be used once per month.
    6 months ago
    by
    BillyB
    Phoenix, NY
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    0
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    Answer: 
    A three pack is for 3 individual doses.
    6 months ago
    by
    James, PetMeds Pro
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    6 months ago
    by
    weiner mom
    new jersey
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    Answer: 
    Yes
    5 months ago
    by
    Philip
    Reidsville
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    Answer: 
    Yes, the medicine is absorbed through your dog's skin and into the bloodstream. When a flea bites them, they ingest the medication and die. You may want to look into K9 Advantix II as it has an added repellent to help repel fleas, mosquitoes and flies.
    6 months ago
    by
    Maureen PetMeds Pro
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    I have heard many of these products bought on line come from overseas. I am wondering where this product is made and shipped from and then delivered to my home?
    7 months ago
    by
    46ford
    KY
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    Answer: 
    Frontline is distributed from France, which is the version sold here in the USA. We ship Frontline Plus from Florida..
    7 months ago
    by
    Cherley Petmeds Pro
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    7 months ago
    by
    Rosie's mom
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    Answer: 
    I wait a week, but I know people who bath their dog within 72 hours.
    7 months ago
    by
    Conners mommy
    Davenport, Iowa
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    Answer: 
    24 hours..
    7 months ago
    by
    Cherley Petmeds Pro
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    I have the FrontlinePlus treatment for dogs weighing up to 22 pounds. My dog only weighs 11 pounds, do I still use the whole vial on my dog?
    7 months ago
    by
    libra
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    Answer: 
    I'd assume you use the entire vial. Why not ask your vet, a person who actually knows something, or check the Frontline webpage.
    7 months ago
    by
    Tillythedog
    WV
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    Answer: 
    yes even it it was a 5 pound poodle you use all that comes in the vial.
    7 months ago
    by
    hornej816
    Lebanon, Tn
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    7 months ago
    by
    Anonymous
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    Answer: 
    3 dose package
    7 months ago
    by
    PKR
    0
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    Answer: 
    This product comes in a 3, 6 or 12 pk.
    7 months ago
    by
    Chris H, PetMedPro
    Florida
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    I have frontline for dogs on hand. The label reads
    "dog 88 - 0.091 fl. oz. Lot. No. 662303. I've lost the main packaging and need to verify if this is for a small dog (15 -20 lbs) or large dog. Can you help me.
    8 months ago
    by
    Anonymous
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    Answer: 
    dog 88 is for a large dog not a small dog.
    7 months ago
    by
    FRONTLINE PLUS FOR DOGS
    New Castle, DE
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    Answer: 
    This would be the one for large dogs.
    8 months ago
    by
    Chris H, PetMedPro
    Florida
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    I have a large breed cat (Maine Coon) he weighs 22 lbs, vet said he is totally normal weight for this breed. He's very large but not fat. The frontline plus for cats does not seem to work but my other 5 are fine and all 6-9 lbs so the frontline plus works great on them. Can I use the dog version which is based on weight or is there something else more effective? My vet is on maternity leave so I can't ask her.
    8 months ago
    by
    Pet lover
    VA
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    Answer: 
    No the ones for dogs should not be used on your cat. We would suggest to try a diffrent product on him such as Advanatage II as he may have built a tolerance to the Frontline Plus.
    8 months ago
    by
    Chris H, PetMedPro
    Florida
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    Answer: 
    I would not think of answering this unless I was a veterinarian. The wrong answer could kill your pet. I'm sure your vet has someone standing in for her if not see another vet.
    8 months ago
    by
    Freddie
    Norco, CA
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    8 months ago
    by
    Anonymous
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    Answer: 
    Most products are only for 12 weeks or older however frontline plus reformulated their product to also be used on nursing dogs and puppies down to 8 wks old. I wouldn't suggest 6 wks just because their organs and stuff is real sensitive and could cause problems but if you decide to I would use a syringe and draw out about .5 ml
    7 months ago
    by
    hornej816
    Lebanon, Tn
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    Answer: 
    No they must be atleast 8 weeks old.
    8 months ago
    by
    Chris H, PetMedPro
    Florida
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    2 answers

    frontline plus cats

    I APPLIED FRONTLINE PLUS TO BOTH OF MY CATS IT HAS BEEN WELL OVER A WEEK SINCE I APPLIED FLP AND BOTH OF MY CATS ARE SCRACHING AND ITCHING ALOT MORE SINCE THE APPLICATION WAS APPLED HELP
    8 months ago
    by
    mandy
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    Answer: 
    Your cats may be allergic ...please check with your vet.
    8 months ago
    by
    Tuffy's Shield
    Weed, California
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    0
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    Answer: 
    We are sorry that you and your furry pals are having trouble with fleas. If they had fleas before the application was used it can take 2-3 months to break the entire flea life cycle. It is important to also treat the surrounding areas to help control the fleas as well.
    8 months ago
    by
    Chris H, PetMedPro
    Florida
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    I am not sure where to apply the medication also not sure which pack to get
    8 months ago
    by
    browneyez
    Tulsa
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    Answer: 
    You apply the medcine at the base of the shoulder blades downwards so your animalt will not be able to lick it off.
    You should just get what you can afford based on your animales weight.
    8 months ago
    by
    Revan
    0
    0
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    Answer: 
    Frontline plus is placed at the base of the neck or the center of your furry pals shoulder blades. As for which one to get this would depend if its for a cat or a dog, and how much they weigh.
    8 months ago
    by
    Chris H, PetMedPro
    Florida
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    Our dog took interceptor but it isn't on the market anymore. The vet gave me sentinel but she still has fleas. Can I use frontline plus for the fleas along with the sentinel for the heartworm.
    8 months ago
    by
    mel
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    Answer: 
    Sentinel is supposed to be for the fleas and the heartworm.
    If it don't work for the fleas I would contact the vet and see if you can use something else for the fleas.
    7 months ago
    by
    FRONTLINE PLUS FOR DOGS
    New Castle, DE
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    Answer: 
    Please consult with your veterinarian.
    8 months ago
    by
    Lilli Pharmacist
    Pompano Beach, FL
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    Two days ago we started a 2-week course of Clavamox, combined with Betagen spray, for 'hot spots' on my dog's head. Will using Frontline plus at the same time interfere with the treatment of the skin infection?
    8 months ago
    by
    Anonymous
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    Answer: 
    The only reason I think I know this answer is because it happened to my dog. He had hotspots because of itching from the fleas. I put the Frontline on Conner away from his hot spots - I usually cut three spots in his hair on his back so I can make sure the meds get into his skin, one being where his tail connects to his body, & within 3 days he started healing beautifully :-) Good luck. If you still aren't sure, I would call your local vet. Good luck!
    7 months ago
    by
    Conners mommy
    Davenport, Iowa
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    Answer: 
    Please consult with your veterinarian.
    8 months ago
    by
    Lilli Pharmacist
    Pompano Beach, FL
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    2 answers

    Frontline plus

    Does this repel Miskitos?
    8 months ago
    by
    Pam
    Tn.
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    Answer: 
    No. Frontline does not repel fleas, ticks, or mosquitos.
    7 months ago
    by
    Smash
    Michigan
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    Answer: 
    Frontline plus does not repel mosquitos, however K9 advantix does repel and kill mosquitos.
    8 months ago
    by
    Stephanie Duesler, Pharm. D, MBA
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    2 answers

    packs clarification

    you have 3 pack, 6 pack, and 12 packs. if there are 6 doses per pack, does that mean the 3 pack has 18 doses?

    Thanks
    8 months ago
    by
    DTL
    Chicago
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    Answer: 
    I just bought a 3 pack of Frontline and it gave me 3 doses which equals out to be 3 months. I am not sure what you are reading. I wish a 3 pack would give me 18 doses! That would be fantastic! Good luck :-)
    7 months ago
    by
    Conners mommy
    Davenport, Iowa
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    Answer: 
    Frontline plus comes in 3, 6 and 12 pack sizes. This mean it comes in 3, 6 and 12 month supplies.
    Ie. (3 pack= 3 doses which lasts 3 months.)
    8 months ago
    by
    Stephanie Duesler, Pharm. D, MBA
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    i put one fronline on my cat on june 13 im flea bombing house now can i put another dose early on my cat now since i flea bombed
    9 months ago
    by
    racki
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    Answer: 
    vets recommend just waiting 2 weeks between doses to prevent irritation.
    9 months ago
    by
    Oscar's Mommy
    San Diego, CA
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    Answer: 
    If necessary you may apply the frontline plus a few days early.
    9 months ago
    by
    Janine M./Pharmacist
    Pompano beach
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    I have a 10 week old kitten. Can Frontline for cats be used on her? She has had two flea dips already before we obtained her, but she really likes hanging out in my basement (which is unfinished) and I would rather be safe than sorry! Any advice??
    9 months ago
    by
    Lucys mom
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    Answer: 
    The instructions say for 6 weeks and older so its safe and treat the basement for flees since she likes to hang out there.
    9 months ago
    by
    grumpybear
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    Answer: 
    Yes, Frontline Plus may be used for kittens 8 weeks or older. However, please consult with your vet
    before applying the product since she has been exposed to a few flea dips.
    9 months ago
    by
    Lilli Pharmacist
    Pompano Beach, FL
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    2 answers

    flea tick control

    My poodle is very allergic to to one of the controls and now I don't know which one I have used both advantix and frontline but there is one ingrediant in one she cannot tolerate did anyone have this problem? Vet doesnt know so I have quit using any help with bad ingrediant?
    9 months ago
    by
    Sue
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    Answer: 
    The best thing for that would be tea tree oil and dawn to get rid of the flees.
    9 months ago
    by
    grumpybear
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    Answer: 
    We are sorry but every pet can have different allergies and we would have no idea without any testing. Please contact your vets office.
    9 months ago
    by
    Chris H, PetMedPro
    Florida
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    2 answers

    Change in Flea Med ?

    I have used Comfortis for a couple of years on my pet, would there be a problem changing to Advantage Plus....tired of having to go to vet for a prescription and office charge ?
    10 months ago
    by
    Jane
    Nashville Tn
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    Answer: 
    Hi Jane,
    I would stay with Comfortis. With my experience every time I have used Frontline or Advantage my pets have gotten fleas. The products are just not effective anymore.
    9 months ago
    by
    Rach
    San Antonio, TX
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    Answer: 
    There shouldn't be a problem changing from the Comfortis, an oral medication for fleas, to the topical advantage II which is over the counter and additionally covers lice. Speak to your veterinarian to see if this would be an appropriate switch.
    10 months ago
    by
    Cheryl-Pharmacist
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    This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
    Note: Any trademarks are the property of their respective companies.
     
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