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Frontline Plus

Starts $53.74 $38.69 
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05-22 lbs
23-44 lbs
45-88 lbs
89-132 lbs
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3 pack
$53.74
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6 pack
$99.98
$79.98
$71.98
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12 pack
$193.70
$154.96
$139.46
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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Frontline Plus?

Frontline Plus is a monthly topical flea and tick preventative for dogs and cats. Frontline Plus kills 100% of adult fleas on your pet within 12 hours and 100% of all ticks and chewing lice within 48 hours. Frontline Plus contains an insect growth regulator, S-methoprene, which kills flea eggs and larvae. It's effective against all stages of the brown dog tick, the American dog tick, the lone star tick and the deer tick (the major carrier of Lyme disease). (3 Pack = 3 doses which lasts 3 months.)

For:

Cats/Kittens and Dogs/Puppies (8 weeks of age and older)

Benefits:
  • Kills all existing fleas on your pet within 12 hours
  • Each application provides a full month of protection
  • Also aids in the control of sarcoptic mange infections in dogs
  • Great for pets that swim since it's waterproof
  • Kills ticks and chewing lice
How it Works:

Frontline Plus contains fipronil, a broad-spectrum insecticide and slow-acting poison that disrupts the central nervous system of fleas and ticks and S-Methoprene, an insect growth regulator that kills flea eggs and larvae. The active ingredients are stored in the sebaceous glands and are wicked out of the hair follicles and continuously re-applied to the coat for long-lasting, waterproof protection.

Cautions:

Your pet may experience some temporary irritation at the site of application. If signs persist or become severe within a few days of application, consult your veterinarian immediately.

Brand Name:

Frontline Plus (Merial)

Generic Name:

Fipronil, S-methoprene

What is Frontline Plus used for:

Frontline Plus provides convenient and effective flea and tick control in dogs and cats, puppies and kittens. It is effective against all stages of the brown dog tick, the American dog tick, lone star tick and deer ticks (the major carrier of Lyme disease). It also kills flea eggs and flea larvae. Frontline Plus rapidly eliminates infestations with chewing lice. Frontline Plus for Dogs and Puppies also aids in the control of sarcoptic mange infections.

Availability of Frontline Plus:

Frontline Plus is a non-prescription (OTC) product.

How Frontline Plus should be used:

Use Frontline Plus for Dogs (fipronil 9.8% and S-methoprene 8.8%) on dogs and puppies 8 weeks or older. Frontline Plus for Dogs is available as 0.67 ml applicators for use on dogs and puppies up to 22 lbs, 1.34 ml applicators for dogs 23-44 lbs, 2.68 ml applicators for dogs 45-88 lbs and 4.02 ml applicators for dogs 89-132 lbs. Wait 24 hours to fully dry before swimming or bathing. Do not reapply for 30 days. Use Frontline Plus for Cats (fipronil 9.8% and S-methoprene 11.8%), available as 0.5 ml applicators, on cats and kittens 8 weeks or older. Place the applicator tip through the animal's hair to the skin level between the shoulder blades. Apply the entire contents of the applicator in a single spot to the animal's skin. Use only one applicator per treatment.

What are the side effects of Frontline Plus:

Pets may experience some temporary irritation at the site of product application. If signs persist or become more severe within a few days of application, consult a veterinarian immediately.

What special precautions are there for Frontline Plus:

This product is for external use on dogs and puppies, cats and kittens 8 weeks or older. Frontline Plus is approved for use on breeding, pregnant, or nursing animals. Consult a veterinarian before using on medicated animals, animals using this product with other pesticides, and debilitated, or aged animals. This product is flammable. Keep away from heat and open flame. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have patient sip water do not induce vomiting unless advised to and patient is conscious. This product can cause eye injury. Flush eyes with plenty of water. Call a physician if irritation persists. Avoid contact with skin, eyes or clothing. Wash thoroughly with soap and water after handling.

In the event of a Frontline Plus overdose:

Contact your veterinarian or veterinary emergency room.

How should I store Frontline Plus:

Store this product at room temperature. Store in the original container only. To dispose wrap original container in several layers of newspaper and discard in trash. Keep out of the reach of children and pets.

How to Use
Directions:
  • Remove the Frontline Plus applicator from the child-resistant package. You can use scissors to snip the foil, or pull the tab to remove the applicator.
  • Snap open the tip of the Frontline applicator - away from your body and face.
  • Part your pet's hair between the shoulder blades until you can see the skin, and place the tip of the applicator on the skin.
Tip:

Wait until application site is fully dry (usually 24 hours) before bathing your pet or letting your pet go swimming.

Dosage:
Dogs/Puppies: (8 weeks of age or older)
Weight
Dosage
Up to 22 lbs
Apply contents of 1 applicator once a month (0.67 ml)
23-44 lbs
Apply contents of 1 applicator once a month (1.34 ml)
45-88 lbs
Apply contents of 1 applicator once a month (2.68 ml)
89-132 lbs
Apply contents of 1 applicator once a month (4.02 ml)
Cats/Kittens: (8 weeks of age or older)
Weight
Dosage
All weights
Apply contents of 1 applicator once a month (0.5 ml)
Horses:
Do not use!
Storage:

Should be stored at room temperature.

Ingredients
Frontline Plus for Dogs & Puppies 8 weeks or older and up to 22lbs:
Active ingredients (per 0.67 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 23-44 lbs:
Active ingredients (per 1.34 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 45-88 lbs:
Active ingredients (per 2.68 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Dogs 89-132 lbs:
Active ingredients (per 4.02 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
8.8%
Frontline Plus for Cats & Kittens 8 weeks or older:
Active ingredients (per 0.50 ml applicator)
Amount
Fipronil
9.8%
(S)-methoprene
11.8%
Customer Reviews
Frontline Plus is rated 3.436 out of 5 by 3,908.
Rated 5 out of 5 by from Terrific price! I was getting this thru the vet, who recommended it after we had a neighbor bring her dog inside and gave fleas to our indoor cat. It worked immediately. Purchasing it here saved me over 10.00$, even with the shipping. Love this site.
Date published: 2016-04-25
Rated 5 out of 5 by from Great product Great product. Does what it says
Date published: 2016-04-25
Rated 5 out of 5 by from Never worry about fleas again! When regular use of Frontline no worry about fleas. Easy to use. Grooming problems after use are non-existent.
Date published: 2016-04-24
Rated 5 out of 5 by from Frontline Plus I have been using Frontline plus for many years and I am very happy with the results as I live in a very highly flea populated area .
Date published: 2016-04-09
Rated 5 out of 5 by from Has worked for years! I have bought Frontline Plus for a number of years for a number of my outdoor cats. They roam 30+ acres of woods and I have not had one issue with fleas or ticks. I believe you can't go wrong purchasing this product.
Date published: 2016-03-23
Rated 5 out of 5 by from Great product. Good price. I shopped around locally to compare prices. 1800petmed with about 10% cheaper.
Date published: 2016-03-05
Rated 3 out of 5 by from Effective product Effective product for fleas but found we also needed to use in conjunction with the flea/tick collar to control wood ticks! We appreciated lower price by using PetMeds, but it took 10 days via Fed Ex to receive! Disappointed in delivery responsiveness.
Date published: 2016-03-02
Rated 1 out of 5 by from Did not work Must have changed it. Because it did not work this time. It had always been quite useful in the past for my dogs. But made the fleas worse if possible this time.
Date published: 2016-02-29
  • 2016-05-01T06:08CST
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Q&A

BoughtFrontline Plus have 2mos on fleas hasn!t let up yet, why?

Asked by: Elloise Amaral
Most flea products kill adult fleas and stop them laying eggs, but none work instantly. In fact most take around 8-24 hours to kill each flea that jumps on your pet. Unlike many parasites, most fleas live in the environment, not on your pet. And there are always plenty of new fleas waiting in the wings, ready to replace those that are killed. It is recommended to treat your home as well when there is a flea infestation. Frontline Plus kills 100% of adult fleas on your pet within 12 hours and 100% of all ticks and chewing lice within 48 hours. We guarantee your complete satisfaction or you get your money back. Please call us at 1-800-738-6337 or email us at customerservice@1800petmeds.com if you need an exchange or refund.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-20

Is it toxic if the cat locks it

Asked by: lindac
The recommended application spot for Frontline is a place where the cat cannot lick, such as the base of the back of the head. Unfortunately, with almost otherworldly contortion abilities, he/she may reach it anyway. If your cat manages to ingest the medication, the side effects are usually mild.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-17

Is it toxic for a cat to lick it

Asked by: lindac
The recommended application spot for Frontline is a place where the cat cannot lick, such as the base of the back of the head. Unfortunately, with almost otherworldly contortion abilities, he/she may reach it anyway. If your cat manages to ingest the medication, the side effects are usually mild.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-19

Does this have a strong smell?

Asked by: GinaM
The Frontline Plus does not have a strong smell.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-08

Price for 12 pk. cat front line says its $139.46, but at check out cost is $154.96. I do not understand.

Asked by: Patricia
It looks like the ten percent discount was not applied at checkout. Please enter code TOP10 in the offer code box located in your shopping cart to receive your ten percent discount. The offer code will bring it down to the sale price listed at $139.46.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-08

Should I give my dog's a bath before using this product?

Asked by: gina
It is safe to use this product 24-48 hours before or 24-48 hours after bathing your furry baby.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-01

I put frontline on multiple dogs, should I keep them separated until it dries?

Asked by: Jnwaller72
Yes, keeping them separate until it dries. which should be about an hour or so, would be a great idea to prevent them from licking each other.
Answered by: Cherley Petmeds Pro
Date published: 2016-03-30

I have the dog frontline plus and it states "do not use on cats". It has the same ingredients, the cat has a little more S-methoprene. If measured correctly, can I use it on my cats?

Asked by: bbeepsue
As a licensed pharmacy, we cannot recommend using the dog Frontline Plus on a cat. This is to prevent over or under medicating your furry baby.
Answered by: Cherley Petmeds Pro
Date published: 2016-03-24
  • 2016-05-01T06:13CST
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