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What is the most important information I should know about cyclosporine modified:
Notify your veterinarian immediately if your pet develops fever or chills, unusual bleeding or
bruising, pale stools, or darkened urine. These symptoms could be early signs of dangerous side
effects.
What is cyclosporine modified: Cyclosporine modified is an immunosuppressant available
by prescription. Cyclosporine modified is FDA approved for use in the treatment of atopic
dermatitis in dogs at least 6 months of age and at least 4.5 pounds. Cyclosporine is not FDA
approved for veterinary use in cats. However, it is a commonly accepted practice for
veterinarians to use this medication in cats. Cyclosporine modified is available as 25mg, 50mg
and 100mg blister packs, each containing 30 capsules. The usual dose of cyclosporine modified
in dogs is 2.5mg/pound and for cats the usual dose is 2.3-3.1mg/pound. The medication is
usually given once a day to start until satisfactory improvement is seen, usually 4 to 8 weeks.
The medication can then be given every other day until the clinical signs of atopic dermatitis
are satisfactorily controlled, then the medication can be given every 3 or 4 days.
What should I discuss with my veterinarian before giving cyclosporine modified: Tell
your veterinarian if your pet has liver disease, kidney disease, cancer, high blood pressure, a
viral, bacterial or fungal infection, or any other serious or chronic condition. Tell your
veterinarian if your pet is pregnant or lactating, and if you plan to breed your pet.
How should this medication be given: Give cyclosporine modified exactly as directed by
your veterinarian. If you do not understand these directions, ask your veterinarian or
pharmacist to explain them to you. Always give cyclosporine modified 2 hours before or 2 hours
after a meal. Allow plenty of water for the pet to drink. Do not remove a capsule from the
blister pack until required for use. When the capsule is removed from the blister pack there is
a characteristic, noticeable smell which is normal. Your veterinarian may want your pet to have
regularly scheduled blood tests during treatment to monitor effectiveness and side effects.
Store cyclosporine modified at room temperature away from moisture and heat.
What happens if I miss giving a dose: Give the missed dose as soon as you remember. If
it is almost time for the next dose, skip the dose you missed and give the next regularly
scheduled dose. Do not give a double dose unless otherwise directed by your veterinarian.
What happens if I overdose the pet: Seek emergency veterinary medical treatment.
What should I avoid while giving cyclosporine modified to my pet: The safe use in
breeding, pregnant or lactating dogs has not been determined. Do not use cyclosporine modified
in dogs with known allergy to the medication. The drug should not be used in dogs with kidney
disease, stomach ulcers, and certain blood disorders. Prolonged use of cyclosporine modified
can result in bacterial or fungal infection related to a decreased effect of the immune
system.
What are the possible side effects of cyclosporine modified: If any of the following
serious side effects occur, stop giving cyclosporine modified and seek emergency veterinary
medical attention; an allergic reaction (difficulty breathing, swelling of the lips, tongue or
face, and hives). Other less serious side effects may occur. Continue giving cyclosporine
modified and talk to your veterinarian if your pet develops vomiting, soft stools or diarrhea,
muscle cramps, muscle weakness, loss of appetite, and change of hair coat. Other side effects
may occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to
the animal.
What other drugs will affect cyclosporine modified: There are many drug/drug
interactions that occur when taking cyclosporine modified. Tell your veterinarian what
medications your pet is currently using and any new products, including herbal remedies you may
start to give. Drug/drug interactions could cause a decrease in effectiveness or an increase in
side effects of either cyclosporine modified or the other medication being given. Examples of
medications that may cause drug/drug interactions are; SMZ-TMP (Bactrim, Septra), gentamicin,
etodolac (EtoGesic), piroxicam (Feldene), ketoconazole (Nizoral), cimetidine (Tagamet),
ranitidine (Zantac), itraconazole (Sporanox), methylprednisolone (Medrol), erythromycin,
Allopurinol (Zyloprim), metoclopramide (Reglan), prednisOLOne, digoxin (Lanoxin), any type of
vaccination.
Where can I get more information: Your pharmacist has additional information about
cyclosporine modified written for health professionals that you can read.
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