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Adequan


 
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  Product Info   How to use   Ingredients   Customer Reviews   Q & A  

What is Adequan?

Adequan Canine (for dogs) is used to control symptoms associated with degenerative or traumatic arthritis. Adequan requires a prescription from your veterinarian. A syringe is needed, but not included in the package. Please see 3cc (3ml) luer lock syringe with 3/4" 25 g Needle.
Adequan for Dogs and Horses
For: Dogs
Benefits:
Helps control non-infectious degenerative or traumatic arthritis
Good for post-surgery treatment
Starts to work within hours and stays in the joint for about three days

How it works:
Adequan inhibits enzymes that break down cartilage within your dog's joints. It reduces inflammation and increases the thickness of joint (synovial) fluid.

Cautions:
Do not give this medication to breeding, pregnant, or lactating animals. Use with caution in animals with kidney or liver disease, or bleeding disorders.


More Information:
Brand Name
Adequan (Manufactured by Luitpold)
Generic Name
Polysulfated Glycosaminoglycan (PSGAG) Solution

What is the most important information I should know about Adequan:
Adequan is a prescription medication used in dogs to control signs associated with degenerative or traumatic arthritis. Adequan Canine 100mg/ml is available by prescription in a box containing 2 x 5 ml vials. The usual dose in dogs is 2mg per lb given by intramuscular injection only, twice a week for up to 4 weeks. Do not mix this medication with other drugs or chemicals.
 
What is Adequan:
Adequan belongs to a unique class of drugs called Disease-Modifying Osteoarthritis Drugs (DMOAD). It is an injectable polysulfated glycosaminoglycan (PSGAG) and is the only FDA approved product of its type. Adequan has been clinically shown to help treat the disease while giving relief from pain. It modifies the disease cycle, stimulates cartilage repair processes and diminishes joint damage while reducing the pain caused by osteoarthritis.
 
What should I discuss with my veterinarian before giving Adequan:
Tell your veterinarian if your dog has any known or suspected bleeding disorders. Tell your veterinarian if your dog has any liver or kidney disease. Tell your veterinarian if your dog is breeding, pregnant or lactating.
 
How should this medication be given:
Give this medication exactly as directed by your veterinarian. Adequan is given by intramuscular (IM, into the muscle) injection. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. If you have difficulty giving the medication, contact your veterinarian. Store Adequan at room temperature (64º-77º F). Keep this medication out of the reach of children and pets.
 
What happens if I miss giving a dose:
Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication.
 
What happens if I give an overdose:
Overdose is extremely rare. Symptoms that may indicate toxicity include joint pain, swelling and lameness.
 
What should I avoid while giving Adequan:
Do not give this medication to breeding, pregnant or lactating animals. Use with caution in animals with kidney or liver disease, or blood clotting or coagulation disorders.
 
What are the possible side effects of Adequan:
Few side effects are seen following Intramuscular injection. Stop giving Adequan and seek emergency veterinary medical attention if an allergic reaction (facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma) should occur. Bleeding from the nose, blood in the feces, or dark and tarry stools may indicate a decreased ability of blood to clot. Contact your veterinarian if you notice these symptoms. Other side effects may also occur. Talk to your veterinarian about any side effects that seem unusual or bothersome to the animal.
 
What other drugs will affect Adequan:
Consult your veterinarian before using any other prescription or over the counter medicines including vitamins and supplements.
 
Where can I get more information:
Your pharmacist has additional information about Adequan Canine written for health professionals that you may read.

Directions:
Adequan is a prescription medication used in dogs for the control of signs associated with
non-infectious degenerative and/or traumatic arthritis of canine synovial joints and following surgical procedures involving a joint.
Tip: Do not give this medication to breeding, pregnant, or lactating animals. Use with caution in animals with kidney or liver disease, or blood clotting or coagulation disorders.
Dosage:
Pet Weight Dosage
Dogs: All weights Inject 2mg per lb given only by intramuscular (IM) injection twice a week for up to 4 weeks (a maximum of 8 injections)
Cats:
Horses:
Storage: Store at room temperature (64-77 F).
Adequan (for Dogs):
Active Ingredients Amount
Polysulfated Glycosaminoglycan 100 mg
benzyl alcohol (a preservative) 0.9% v/v
water  

Other Ingredients:
Sodium hydroxide and/or hydrochloric acid added when necessary to adjust pH. Sodium Chloride may be added to adjust tonicity

Adequan 4.7 5 68 68
Adequan For Dogs Adequan product review: One of the first products of its kind in veterinary medicine, now in use over many years and thousands of dogs and happy dog guardians , my clinical experience with this pioneering injectable FDA approved joint supplement has also been very positive. By injecting this product intramuscularly, one avoids some of the problems with absorption that is occasionally seen with other natural joint supplements given orally. The polysulfated glycosaminglycan solution quickly goes to the joints that need it, modifying the disease process of degenerative joint disease, by inhibiting enzymes that break down the supportive cartilage of the joints, while at the same time increasing the thickness of the lubricating joint fluid, just as shock absorbers do for ones automobile. The results are a decrease in inflammation and joint pain. I have even used this product in cats on occasion with terrific results, which is so important, given the paucity of effective and safe drugs for cats available on the market for arthritis. Results can be seen within hours to days. I usually will follow the manufacturer's recommendations giving it twice weekly for first 4 weeks. Some pets will have long term relief, while others will need periodic injections anywhere from every 2-4 weeks. I will often combine use of this product with omega 3 fatty acids, as well as antioxidants like proanthozone, also available from 1800petmeds, and find that with this multipronged supplement approach, that I often can avoid the need for stronger prescription drugs which may have occasional side effects. The only side effects I have occasionally seen in animals is very rare bleeding tendencies. This is best avoided by having blood work done first by your veterinarian to make sure there are no pre existing problems of the liver or kidneys that may predispose to this. The only other negative I can see is the need to get your vet to write a prescription for it, and the need for some clients to get over the fear of learning how to give these injections to their pets at home. Once I have shown clients the first time, they often find it quite easy and money saving to do right at home themselves. I give this product an overall efficacy rating of a 5, with an ease of use a 3. . 04/20/2009
I had my elderly Akita on Adequan and between that and acupuncture she lived to be 13 1/2 and was able to get around and lead a good life. I now have my 4 year old Akita on it. He has elbow dysplasia and even though he had surgery to help the problem, this seems to be keeping swelling and any need to limp away. I do think it's beneficial. 03/03/2014
Excellent Product My 25 pound 9 year old corgi was diagnosed with terrible arthritis in her front elbows. We used to be able to walk about 3 miles a day but it got to the point that she could barely make it around the block. I have been using Adequin now for over 2 months, starting with twice a week, to once a week and now to once every two weeks and eventually once a month. While she still limps a little we are now back to our regular walks and combined with Metacam she seems to be doing great. I just found Adequin on 1800PetMeds and it is $50 less expensive than my vet. I will order her meds now through this website when she is due for more. 02/15/2014
Really helped my Dog My dog needed to be taken off of Rmadyl due to damage it seemed to be causing her liver, so the vet recommended we try adequan instead. Wow! Wish we had switched sooner. It is expensive, but it really made a difference. We started with two doses a week for the first month and now are down to once a week. She has been on it for about 2 months now. We hope to try to decrease to two times a month soon. She is a 13 year old Shepard/cattle dog mix. It does not seem to help too much with some localized arthritis she has in a front elbow, however it seems to make such a big difference everywhere else that is she is able to favor that side without seeming like she is in pain all over. She is able to go on longer walks again and even runs around once in awhile. She is also on Tramadol. She was previously on Rimadyl and Tramadol, and is now on Tramadol and Adequan. She looks better now then she ever did on the Rimadyl. 02/08/2014
good and safe product I have used Adequan for both equines and canines with really good results and without fear of side effects. I would encourage people to try it sooner for a better quality of life for your pet. 02/08/2014
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98 Questions · 122 Answers

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1 answer

Adequan for dogs

I have a 19 lb. pug, the vet has suggested I read about Adequan. As the medication is expensive how long can I expect a vial to last? The recommended dosage was once weekly for 6 weeks, then once a week for 6 weeks and then once monthly.
2 weeks, 6 days ago
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kjo
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Answer: 
please call our pharmacy so we can give you the best answer. How many ml's did the vet
instruct you to give ?
2 weeks, 1 day ago
by
Linda M 1800petmeds pharmacist
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4 weeks, 1 day ago
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Kanch
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Answer: 
The response to the medication depends on the severity of the arthritis in your dog, you may need to use additional pain medication to alleviate the pain.
4 weeks ago
by
Pharmacist
Pompano beach
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1 month, 1 week ago
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Kanch
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Yes, these medications can be used together
1 month ago
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Linda M 1800petmeds pharmacist
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When will Adequan for canines be available for purchase again?
7 months ago
by
Anonymous
Ferndale, MI
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We are expecting the target date for product availablilty to be between October and January.
7 months ago
by
Lisa M
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1 answer

Adequan canine

Do you have availability for one box (2 vials ) to deliver currently? I know the manufacturer has stopped production of this product, so looking for immediate delivery.
8 months ago
by
Picasso
ca
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No, this medication is currently out of stock. You may discuss other alternatives with your veterinarian such as oral Metacam, Novox and Previcox.
8 months ago
by
Stephanie Duesler, Pharm. D, MBA
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This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
 
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