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Vetsulin Insulin

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40 units/ml 10 ml Vial
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Product Info
How to Use
Customer Reviews
Product Info
What is Vetsulin Insulin?

Vetsulin (porcine insulin zinc suspension) is the first and only FDA-approved insulin available in the U.S. for treating diabetic dogs and cats. Vetsulin controls levels of glucose in the blood to help alleviate diabetic symptoms. It's used with U-40 insulin syringes (sold separately). Vetsulin requires a prescription from your veterinarian. Vetsulin Insulin requires refrigeration and must be kept at refrigerator temperatures at all times. To ensure proper temperature, it requires overnight shipping at an additional cost.


Dogs and Cats

  • Controls your pets glucose levels and alleviates symptoms of diabetes.
  • Improvement can usually be seen within a few days.
  • First and only FDA-approved pet insulin available in the U.S.
How it Works:

Insulin is a hormone that is naturally produced by the pancreas. When the body does not produce enough insulin, or when the insulin produced is not effective, it results in diabetes mellitus. Vetsulin is an aqueous suspension of porcine (pork) insulin that controls hyperglycemia in pets with diabetes.


Insulin requires refrigeration. Overnight shipping is required and additional shipping charges are applicable. Rarely, allergic reactions can occur. Seek emergency veterinary medical attention if your pet experiences hives, difficulty breathing, or swelling lips, tongue, or face.

Brand Name:


Generic Name:

Porcine Insulin Zinc Suspension

What is the most important information I should know about Vetsulin:

Diabetes mellitus is a disease where the body produces insufficient insulin. The low insulin levels may result in high blood glucose that could produce the following changes in a dog or cat: increased thirst, urination and appetite, weight loss, high levels of glucose in the urine, ketones in the urine, cloudy eyes and vision loss (diabetic cataracts). Vetsulin is not a cure for diabetes mellitus, it can control or eliminate many of the complications associated with the disease (such as excessive thirst, urination, and weight loss) and prevent development of life threatening ketoacidosis. Response varies from animal to animal but can be dramatic. In most cases improvement can be seen within a few days. In cats, treatment may lead to diabetes remission (insulin injections no longer required). If Vetsulin is discontinued or not given as directed, the signs of diabetes will likely return and life-threatening complications such as ketoacidosis may develop.

What is Vetsulin:

Vetsulin is a sterile aqueous zinc suspension of purified porcine insulin. Insulin is a hormone naturally produced by the pancreas. Insulin enables the body to use the sugar in food as a source of energy. When the body does not produce enough insulin, or when the insulin produced by the body is not effective enough, this condition is called diabetes mellitus. This condition allows sugar levels in the body to become very high. Vetsulin is Purified porcine (pork) insulin Zinc Suspension that is used to control hyperglycemia in dogs and cats with diabetes mellitus. Vetsulin is available by prescription as a 10 ml multi-dose vial containing 40 units (U) per mL of porcine insulin zinc suspension per ml and is given to dogs or cats by subcutaneous injection.

What should I discuss with my veterinarian before giving Vetsulin:

Do not give Vetsulin if your pet is allergic to pork or pork products. Before using Vetsulin, tell your veterinarian if your pet has any other medical conditions such as: vomiting and/or diarrhea, shows signs of extreme drowsiness or fatigue (lethargy), and/or shows signs of severe ketoacidosis. Tell your veterinarian if your pet takes any other prescription or over the counter medications, including vitamins, minerals, and herbal supplements. Tell your veterinarian if your dog or cat has any liver or kidney disease; inflamed pancreas (pancreatitis), underactive (hypo) or over-active (hyper) thyroid, Cushing's disease or if your dog or cat is pregnant, nursing, or if you plan to breed your dog or cat.

How should this medication be given:

Vetsulin should be given according to your veterinarian's instructions. Vetsulin is given using a U-40 syringe only. Use of a syringe other than a U-40 syringe will result in incorrect dosing. Vetsulin should not be shaken. Just prior to use, the vial should be mixed by rolling the vial between the palms of your hands 10 times. Do not reuse a syringe. Dispose of all syringes in an appropriate puncture-resistant disposal container. Vetsulin should be stored in an upright position under refrigeration (36º-46º F). Do not freeze. Protect from light. Keep this medication out of the reach of children and pets.

What happens if I miss giving a dose:

Follow your veterinarian's directions if you miss giving a dose of Vetsulin. To prevent missed doses, be sure to always have enough Vetsulin on hand.

What happens if I overdose the pet:

Contact your veterinarian immediately if you inject more than the prescribed amount of Vetsulin.

What should I avoid while giving Vetsulin:

Vetsulin should be given to dogs and cats only. Vetsulin should not be administered to humans. Call a physician immediately if you accidentally inject yourself with Vetsulin. Do not give a dose of Vetsulin to a pet experiencing an episode of low blood glucose (hypoglycemia). Common causes for hypoglycemia include excessive doses of insulin, failure to eat, accidental doubling of insulin dose, and strenuous exercise.

What are the possible side effects of Vetsulin:

Rarely, allergic reactions to insulin can occur. Seek emergency veterinary medical attention if an allergic reaction is experienced (difficulty breathing, swelling of the lips, tongue, or face, or hives). Other serious side effects can occur with or without warning. The most common insulin-related side effect is low blood sugar (hypoglycemia) with symptoms that include; lethargy, staggering gait, seizure or coma. Contact your veterinarian immediately if your pet has a medical problem or side effect from Vetsulin therapy. Other side effects may occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What other drugs will affect Vetsulin:

Vetsulin can be given with other medications, but the dose may need to be adjusted due to the medication resulting in either increased or decreased insulin requirements. Progestogen (such as megestrol) and glucocorticoids (such as cortisone, prednisone, dexamethasone, triamcinolone) should be avoided during Vetsulin therapy. Progestogen, glucocorticoids, and certain endocrine diseases may counter the effect of insulin. Do not give any other prescription or over the counter medications, including vitamins, minerals and herbal products, without first talking to your veterinarian or pharmacist during treatment with Vetsulin.

Where can I get more information:

Your pharmacist has additional information about Vetsulin written for health professionals that you can read. 

How to Use
  • Vetsulin (porcine insulin zinc suspension) is a prescription medication used to control hyperglycemia in dogs and cats with diabetes mellitus.
  • Vetsulin is available in 10ml vials containing 40 U/ml.
  • Vetsulin is given subcutaneously (SQ) using a U-40 insulin syringe only. Use of an insulin syringe other than a U-40 syringe will result in incorrect dosing.

Just prior to use, the vial should be mixed by gently rolling the vial between the palms of your hands 10 times.

All weights
Vetsulin should be given according to your veterinarian's instructions using a U-40 syringe only
Do not use!

Vetsulin should be stored in an upright position in the refrigerator. Do not freeze, protect from light.

Vetsulin Insulin:
Active Ingredient (per mL)
Porcine Insulin Zinc Suspension
40 U
Zinc Chloride
0.08 mg
Sodium Acetate Trihydrate
1.36 mg
Sodium Chloride
7.0 mg
Methylparaben (preservative)
1.0 mg
*pH is adjusted with hydrochloric acid and/or sodium hydroxide.
Customer Reviews
Vetsulin Insulin is rated 4.4375 out of 5 by 32.
Rated 5 out of 5 by from Has worked wonders I have been using vetsulin for over a year my cat is a diabetic the other insulins just weren't working for him. I also changed his diet. High protein low carbs no grains. Dry food is his treats we use canned food its better on his kidneys. Great improvement.
Date published: 2016-10-06
Rated 1 out of 5 by from What?????? I can get this same insulin from my vet for 35.00. I thought medication was supposed to be cheaper here>
Date published: 2016-09-10
Rated 5 out of 5 by from Working Great for Turbo! Turbo, our miniature wire-haired Dachshund, is a mill dog rescue. He is diabetic, has Cushings disease and an auto-immune disorder. The Cushings makes it harder to control his diabetes, so we have had to increase his Vetsulin dose quite a bit since his diabetes diagnosis a few months ago. His diabetes is currently under control, and he seems to be a happy guy.
Date published: 2016-03-13
Rated 5 out of 5 by from Works great. We switched to Vetsulin several months ago. It is nearly half the cost of Lantus and works just as well. Because we give a larger amount of Vetsulin (3 vials equal one of Lantus) we've started using U40 syringes which are easier to read. So, all and all it is a win. I would recommend it to anyone.
Date published: 2016-03-11
Rated 5 out of 5 by from Vetsulin Insulin ..convenient and a GREAT buy!! My vet charges $60 for insulin and $50 for 100 needles and needle dispenser. For $200 I was able to purchase 2 bottles of insulin and 400 needles. I'm VERY PLEASED.
Date published: 2016-03-11
Rated 5 out of 5 by from Vet put my kitty on Vetsulin. Unfortunately it is not controlling his diabetes. She wanted to put him on Levemir, which is beyond my budget. I told her I would continue with the Vetsulin, which is better than not. I don't think it is the insulin, I just think kitty is becoming resistant to anything.
Date published: 2016-01-18
Rated 5 out of 5 by from It made my dog his old self again. Great product. Great customer service. I love using 1800pet Meds.
Date published: 2015-12-18
Rated 4 out of 5 by from Works ok, do refrigerate it! Review of PetMeds in general: Fast delivery as promised, very polite and competent phone and computer customer service. Vetsulin: Hard to review a prescription product really but here's my experience: my vet had me try Vetsulin since Humulin did not work on my dog at all (Humulin is more easily available and at that time cheaper though this is probably no longer true#. His blood sugar levels have improved so-so on Vetsulin which is better than nothing on Humulin. We are gradually increasing the dose to see if those can be improved. My vet reminds me that you DO have to shake Vetsulin a little before using. #unlike Humulin which under no circumstances should the bottle be shaken) Caution - I believe I had a big problem for a few days when I accidentally left the bottle out for about 12 hours. You should always always refrigerate! I used it anyway because I was 'broke' and couldn't afford to buy more. My dog became very symptomatic, urinating a lot and stumbling around in an uncoordinated way. When I finally got paid and could buy more, he did get better again. I don't know if the nonrefrigeration just made it lose effectiveness or if it actually 'went bad' but I do not want to risk this again! Anyway, there's hope that we'll find a dose that works. Diabetes is almost completely unknown in Ibizans and there's no hereditary background for him based on info I trust. I don't know why he got it but he had become overweight which was strange since most Ibizans are very light eaters.
Date published: 2015-08-14
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My vet as prescribed my dog human insulin 9 units twice a day. If I switch my dog to vetsulin will the dosage be the same or would it be adjusted. Thanks.

Asked by: Rachel H
The dosage for human insulin is usually 100 units/mL, while Vetsulin is 40 units/mL. Therefore, your vet would need to adjust your dogs dosage if you are going to switch from human insulin to vetsulin.
Answered by: Christine
Date published: 2016-10-10

I have a prescription for my cat for PZI. It says Siq: 1 unit SQ BID. My Vet said this medicine is the cheapest, Is this vetsulin? If not, what is it she prescribed? Thank You!

Asked by: bobesioux
PZI is a type of Insulin. It is not exactly the same as Vetsulin, which is also a type of insulin.
Answered by: Christine
Date published: 2016-10-05

I currently purchase Vetsulin from a different company for my cat.. if I purchase from you do I need my Veterinarian's approval? I purchase it with a company he is hooked up with.

Asked by: RMACSR
Yes, you do need your verterinarian's approval to purchase Vetsulin. At checkout, we will ask for your vets information and contact them for approval to fill this prescription.
Answered by: Christine
Date published: 2016-09-28

Hi.. can u deliver it to India also.. and pls confirm if any additional charges applicable. Thanks 

Asked by: Nitin
Unfortunately, we do not ship insulin to India. To ensure proper temperature, Vetsulin requires overnight shipping and we do not have an overnight shipping option for orders shipped to India. We do ship other products to India via Global Priority mail at a shipping fee in the amount of $14.99.
Answered by: Cherley Petmeds Pro
Date published: 2016-02-02

Does Vetsulin expire like Lantus/Glargine?

Lantus/Glargine expires 28 days after the first needle stick whether it's refrigerated or not. Because of this, I am throwing out 2/3's, only using 1/3, every 28 days and paying $270 per 100ml Lantus bottle. Does Vetsulin have an expiration date?
Asked by: SuzanneK
From the leaflet: Use contents within 42 days of first vial puncture.
Answered by: Sundance Cat
Date published: 2016-01-19


My dog is on humilinN insulin do you carry this item or is there something similar
Asked by: Candi
Hi we do not carry humilin N. Vetsulin is a great insulin however you would need to consult your vet prior to changing your pets insulin.
Answered by: James PetMeds Pro
Date published: 2015-10-03

Do I need a prescription for this since it is for my dog?

I am not sure how expensive it will be from the Vet because I am a newly diabetic diagnosed doggy. My mommy is trying to save money wherever she can. Also, does my mommy need a prescription for the needles and the storage container? Thanks, Diamond
Asked by: Diamond
Vetsulin will require a prescription from your veterinarian. The syringes are over the counter in some states and prescription required in others. You will need a prescription from your veterinarian for syringes if you reside in Connecticut, Delaware, New Hampshire, New Jersey, Oklahoma, Florida (Broward and Dade counties) or New York.
Answered by: Kelly P
Date published: 2015-03-31

If Vetsulin is not available in the USA then how do i get it?

Asked by: MARLEY
The best place to look for this is on-line, there may be some independant pharmacy's that can order this for you, or ask your veterinarian if he could prescribe another type of insulin. Thanks for your question.
Answered by: Marty, Pharm. D.
Date published: 2012-10-11
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