What is Vetoryl?
Vetoryl is used to treat dogs with hyperadrenocorticism (Cushing's Disease). Vetoryl (Trilostane) is a competitive inhibitor of the enzyme 3-beta-hydroxysteroid dehydrogenase used in dogs for the treatment of pituitary dependent Cushing's Disease and Cushing's Disease due to adrenocortical tumors. It may be necessary to wait at least one month after discontinuing Lysodren before starting treatment with Vetoryl. Vetoryl requires a prescription from your veterinarian.
Dogs & Puppies (weighing 3.8+ lbs)
- Treats Cushing's Disease in dogs and puppies weighing over 3.8 lbs
- Improvement may be seen within several weeks
- Available in 10 mg, 30 mg, 60 mg or 120 mg capsules (based on weight)
How does Vetoryl work?
Vetoryl controls the adrenal gland's excess production of cortisol, a hormone released into the bloodstream during times of stress.
Do not give this medication to dogs with kidney or liver disease. Vetoryl Capsules should not be given to dogs taking certain medications or dogs that are pregnant. Speak with your veterinarian about all medications your dog is taking, including over-the-counter medicines.
What is the most important thing I should know about Vetoryl?
Vetoryl is a prescription medication FDA approved for veterinary use in the treatment of Cushing's Disease. Vetoryl is indicated for use in pituitary-dependent hyperadrenocorticism. Vetoryl also has a Minor Use designation for treatment of Cushing's Disease caused by adrenal tumors. Vetoryl is available as 10 mg capsules, 30 mg capsules, 60 mg capsules and 120 mg capsules. The usual initial starting dose to treat Cushing's Disease in dogs is 1.0 to 3.0 mg/lb given once a day based on body weight and capsule size. For dogs weighing 3.8-10 lbs, give one 10 mg capsule once a day. For dogs weighing 10-22 lbs, give one 30 mg capsule once a day. For dogs weighing 22-44 lbs, give one 60 mg capsule. For dogs weighing 44-88 lbs, give one 120 mg capsule. For dogs weighing 88-132 lbs, give one 120 mg capsule and one 60 mg capsule, totaling 180 mg. For dogs weighing over 132 lbs, give the appropriate combination of capsules. Vetoryl should be given with food. After approximately 10 to 14 days, your pet will need to be re-examined and dosage adjustments may be required. Pets may require further re-examination at 30 days, 90 days, and every 3 months thereafter.
What should I discuss with my veterinarian before giving Vetoryl to my pet?
Tell your veterinarian if your pet has kidney or liver disease. Tell your veterinarian about any other medical problems or allergies your dog has now or has had in the past. Tell your veterinarian about any medications your dog is taking including over the counter products and nutritional supplements. Tell your veterinarian if your pet is pregnant, nursing, or if you plan to breed your dog.
How should Vetoryl be given?
Give this medication exactly as directed by your veterinarian. Give this medication with food. Do not open capsules and do not attempt to split or divide capsules. Wash your hands after use. Do not handle the capsules if you are pregnant or trying to become pregnant. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you.
What are the potential side effects of Vetoryl?
If any of the following serious side effects occur, stop giving Vetoryl and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), severe depression, bloody diarrhea, collapse, or other severe reactions. Other less serious side effects such as unexpected decrease in appetite, vomiting, diarrhea, and lethargy may occur. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.
What happens if I miss giving a dose of Vetoryl?
Give the missed dose as soon as you remember. However, if is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.
What happens if I overdose my pet on Vetoryl?
Seek emergency veterinary medical treatment. Symptoms of Vetoryl overdose may include lethargy, weakness, vomiting, or collapse.
What should I avoid while giving Vetoryl to my pet?
Do not give Vetoryl to dogs with kidney or liver disease. Do not give to pregnant or nursing dogs or dogs intended for breeding. Do not touch Vetoryl capsules if you are pregnant or trying to become pregnant.
What other drugs will affect Vetoryl?
Before giving Vetoryl, tell your veterinarian if your pet is also taking ACE inhibitors such as enalapril, potassium sparing diuretics such as spironolactone, ketoconazole, or potassium supplements. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines or nutritional supplements.
- Vetoryl is used to treat dogs with hyperadrenocorticism, also known as Cushing's Disease.
- Vetoryl capsules should be given with food.
Do not open capsules and do not attempt to split or divide capsule.
Dogs/Puppies (weighing 3.8+ lbs):
One 10 mg capsule daily
One 30 mg capsule daily
One 60 mg capsule daily
One 120 mg capsule daily
One 120 mg capsule plus one 60 mg capsule daily (180 mg total)
Over 132 lbs
Administer the appropriate amount of capsules based on your dog's weight. Speak with your veterinarian to help you determine the correct dosage for your dog.
Store Vetoryl at controlled room temperature (77°F) with excursions to 86° F allowed. Keep this medication away from children and other pets.
Vetoryl is rated
Rated 1 out of
Thus is almost $20 more than my Vets office
Date published: 2016-09-28
Rated 5 out of
My doxie Sandi was diagnosed with cushings at age 10. She was on the meds for 5 years until she passed this year at age 15. Once a dog is diagnosed with cushings, they are expected to live an average of 3 more years before the tumor can no longer be managed. My Sandi lived for 5 years. Vetoryl was amazing for her. Within weeks of starting it, she showed huge improvements. She lived a full and happy life with no side effects from the medication. It helped give us many great years together. It was also much cheaper than the original meds my vet wanted to prescribe.
Date published: 2016-04-16
Rated 5 out of
I bought Vetoryl because the vet advise my family it would help our dog (lapsa apso), she was diagnosed with cushing disease and she lost all her hair and energy. After just 5 months she has improved incredibly and her hair is growing back FAST!
Date published: 2016-03-27
Rated 5 out of
Meds have helped!
Since my dog has been on the vetoryl capsules, she seems to her old self.
That have made a difference in her quality of life.
Date published: 2016-03-12
Rated 5 out of
The product has helped my dog greatly.
The product is excellent. The price on this website is outrageous. I can get it for much less at my vet's office.
Date published: 2014-03-08
Rated 5 out of
Wonderful for Cushings Syndrome
Our girl, Molly, an Australian Cattle Dog, was drinking water and eating all the time. She would even eat rocks as she was thinking she was thirsty and hungry all the time. She got so fat and we were cleaning up "accidents" all the time. I found what I thought was her problem on the internet and advised our Vet of what I thought it was. We did all the "tests" and nothing was conclusive. But convinced Vet to put her on a Cushings Medication. She choose Vetoryl 120 mg. It took a couple of weeks before we noticed a difference. It has been 5 months and Molly is back to herself! Her eyes were bulging as she has the Pituitary Cushings, her stomach was huge and she had no energy, her fur was falling out and she had no muscle tone. She is now acting like a pup again and she is 11 years old. Amazing stuff! Thank you God!
Date published: 2013-07-20
Rated 1 out of
Careful of Diagnosis and Dose
Vet determined our German Shorthair had Cushings. Prescribed 60mg dose for 60# dog. Caused her to pace uncontrollably and lose balance. Backed off to 30mg dose with similar results in about 5 days of drug. Have backed her off of Vetoryl completely - she was much healthier and happier without this prescription. Not clear why it didn't work for our dog.
Date published: 2013-02-06
Rated 5 out of
Wow, We too have a 14 year old cocker spaniel and she had uncontrollable shakes and panting. drinking water non stop and urinating uncontrollably.my wife diagnosed using internet. Vet prescribed Vetoryl capsules and it saved her life, shes old but is back to normal, if we miss a day on the pill she gets symptoms right back so we give it to her every other day and shes just fine. Thanks, Tony
Date published: 2012-02-03