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Primor

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is Primor?

Primor (sulfadimethoxine/ormetoprim) is a broad-spectrum antibiotic combination used to treat susceptible bacterial infections in dogs. Primor requires a prescription from your veterinarian, and is sold per tablet.

For:

Dogs

Benefits:
  • Treats skin and soft tissue infections (wounds and abscesses)
  • Also effective against urinary tract infections caused by susceptible bacteria
  • Single, comparatively low dose provides rapid and sustained therapeutic blood levels
How it Works:

Primor is made up of two antibiotics

Cautions:

Do not use in pregnant or nursing animals. Your pet should be encouraged to drink plenty of water while being given Primor. Before giving Primor, be sure to tell your veterinarian what other medications or treatments your pet is receiving.

Brand Name:

Primor Tablets (Pfizer Animal Health)

Generic Name:

Sulfadimethoxine/Ormetoprim

What is the most important information I should know about Primor:

Primor is a prescription medication FDA-approved for veterinary use in dogs. Primor is available as scored tablets in two strengths: Primor 240 containing 200mg sulfadimethoxine and 40mg ormetoprim, and Primor 1200 containing 1000mg sulfadimethoxine and 200mg ormetoprim. The usual initial starting dose is 25mg/pound on the first day of treatment followed by 12.5mg/pound given once a day. Treatment should continue for 2 days after symptoms disappear. However, treatment should not exceed 21 consecutive days. Always follow the dosage instructions provided by your veterinarian. Do not give Primor to any pet other than the pet for whom it was prescribed. Primor is not for use in animals allergic to it or other sulfa drugs.

What is Primor:

Primor is a potentiated sulfa drug used in dogs for the treatment of skin and soft tissue infections (wounds and abscesses), and urinary tract infections caused by susceptible bacteria. Primor may also be used for other conditions not listed.

What should I discuss with my veterinarian before giving Primor to my pet:

Tell your veterinarian if your pet is allergic to Primor or other sulfonamides (sulfa drugs). Tell your veterinarian if your pet has liver disease or blood dyscrasias, is dehydrated, or is pregnant or lactating. Also tell your veterinarian what other medication, including vitamins and supplements, that you are giving your pet while giving Primor.

How should this medication be given:

Give this medication exactly as directed by your veterinarian. Give Primor by mouth. It may be given with food. Leave plenty of water for your pet to drink. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Primor at room temperature in a tight, light-resistant container. Keep this medication away from children and pets. 

What happens if I miss giving a dose:

Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose the pet:

Seek emergency veterinary medical treatment. Symptoms of overdose may include side effects listed below and may also include behavioral changes.

What should I avoid while giving Primor to my pet:

Antacids may decrease the effectiveness of sulfa drugs such as Primor. Give antacids 2-3 hours before or after giving a dose of Primor.

What are the possible side effects of Primor:

Sulfa crystals may appear in your pet's urine. Your pet should be allowed to drink plenty of water while taking this medication. Other side effects that may occur include KCS or dry eye, anemia, fever, loss of appetite, vomiting or diarrhea, joint inflammation, kidney damage, or skin rash. Stop the medication and contact your veterinarian if any of the above symptoms occur. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet. If your pet experiences an allergic reaction, signs may include facial swelling, hives, scratching, and sudden onset of diarrhea, vomiting, shock, seizures, or coma. If these signs occur, contact your veterinarian immediately.

What other drugs will affect Primor:

Before giving Primor, tell your veterinarian if your pet is being given methotrexate, warfarin, phenylbutazone, thiazide diuretics, aspirin, probenecid, or phenytoin.

Where can I get more information:

Your pharmacist has additional information about Primor written for health professionals that you may read.

How to Use
Directions:
  • Primor is a prescription medication used in dogs for the treatment of skin and soft tissue infections (wounds and abscesses), and urinary tract infections caused by susceptible bacteria.
  • Pets should be encouraged to drink plenty of water while being given Primor. Primor may be given with food.
Tip:

If your pet shows no improvement after 2 or 3 days, have your veterinarian re-evaluate your pet's diagnosis. Treatment should not exceed 21 consecutive days.

Dosage:
Dogs:
Weight
Dosage
All weights
The initial dose is 25mg per pound of pet's body weight on the first day of treatment followed by 12.5mg per pound of pet's body weight given once a day thereafter. Treatment should continue for at least 2 days after symptoms disappear.
Cats:
Do not use!
Horses:
Do not use!
Storage:

Store this medication at room temperature away from moisture and heat.

Ingredients
Primor 240:
Ingredient
Strength (per tablet)
Sulfadimethoxine
200 mg
Ormetoprim
40 mg
Primor 1200:
Ingredient
Strength (per tablet)
Sulfadimethoxine
1000 mg
Ormetoprim
200 mg
Customer Reviews
Primor is rated 2.7333333333333334 out of 5 by 15.
Rated 3 out of 5 by from Skin Infection My dog is using the Primor 600 Mg. It has caused a loss of appetite. She usually has a good appetite. Also I noticed some of the rash from the skin infection is still there and will call my doctor today. So far she has been on it for 7 days.
Date published: 2014-09-22
Rated 5 out of 5 by from effective I am using this for a second time in 4 months to treat diarrhea/bowel incontinence in my 8 year old malti-poo. The vet thinks she might have been suffering from a bacterial overload, and both times this has cleared up the symptoms quickly, with no side effects.
Date published: 2014-01-18
Rated 5 out of 5 by from Primore only med to help uti. My Pittie had a chronic uti for months with no reliefe from other antiboditics. Primor is the only med strong enough that has cleared up the uti issue for my dog. I would definitely use again because I have tried everything else.
Date published: 2013-04-18
Rated 4 out of 5 by from Primor 240 My 2 year old dog had a bacterial infection from scratching due to dermatitis. My vet prescribed this for him to take 12 days. He had no side effects and is back to his normal self. I did ask my vet questions about the medicine when given to me though. After all, he is my kiddo and I wanted to be sure of everything before administering it to him.
Date published: 2013-03-22
Rated 1 out of 5 by from I do not recommend My shepherd mix was given this for her respiratory issues a couple of years ago. A couple of days into the medication she had a seizure and fell off of the couch. I stopped the medicine at once and she has never had a seizure since then. There are other medications that can be given in place of this that I feel do the job better and are a lot less dangerous!
Date published: 2012-03-29
Rated 1 out of 5 by from STAY AWAY FROM PRIMOR I have six schnauzer's. The first time I used primor on one of my schnauzer's it was used to prevent bladder stones. My poor girl developed dry eye that they say may never clear completely. She may have to have surgery to treat this. Another one of my girls was given Primor for a bladder infection. She developed nausea and diarhea(with severe bleeding) and refused to eat for six days and was severely dehydrated. She is 12 years old, and I thought for sure I was going to lose her. She is FINALLY doing better, but now I am having trouble getting her weight back up. I will NEVER use Primor again. As far as I am concerned it should be outlawed.
Date published: 2011-12-28
Rated 1 out of 5 by from Primor caused my dog to Shake and was Scared! :( My poor Maltese, who is 6 yrs old had bladder surgery to remove a stone. 2 weeks after surgery he continue to have urges to urine. Took him to the Vet and they gave him Primor to address a new UTI. The first Dose was strong (2 tablets, 240 each). NEVERA AGAIN! My dog reacted so strange to it . My husabnd went to kiss him and he jumped out of his skin. He was shaking like a leaf. Walking around the house with his tail down. Ended up going to the emergency. They gave him a Valium IV to calm him down and had a fever of 102.9.....AWEFUL EXPERIENCE! The E.R Vet said this is an OLD Drug with too many side effects. He informed us that the newer drugs don't have as many side effect........My little guy was freaked out! I thought something was going to happen. What a scary experience! Becareful--I would hate for your dog to experience the same thing!
Date published: 2011-05-08
Rated 5 out of 5 by from worked great I had this prescribed for a uti/uterus infection that would not clear up with another antibiotic. It worked wonderful and the dog is happy and healthy now. No side effects.
Date published: 2011-02-17
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Q&A

Benefit of primor vs. bactrim for staph infection?

My English bulldog has severe pododermatitis with a deepening wound that was cultured, staph and e. coli present. Primor was ordered by vet for $145. What is the benefit of such a costly medication as opposed to Bactrim DS? Is there $145 worth of efficacy to justify the Primor?
Asked by: Andrea
The Primor is a more broad spectrum antibiotic that will cover the staph infection.
Answered by: Kelly P
Date published: 2015-04-09

can Primor be used for ear infections in dogs?

Asked by: Laura B
Primor is a prescription medication typically used in dogs for the treatment of skin and soft tissue infections (wounds and abscesses), and urinary tract infections caused by susceptible bacteria. If your pet has an ear infection please contact your veterinarian to suggest an appropriate course of treatment.
Answered by: Stephanie Duesler, Pharm. D, MBA
Date published: 2015-01-14

Can Primor be crushed?

Our dog has a large aversion to taking pills. Is Primor a pill that can be crushed and put in the dog's food.
Asked by: chuckie
Hi, I would not recommend crushing the tablet, because the medication may lose it's effectiveness if all of the active ingredient is not ingested; however, it can be administered with food. Thanks!
Answered by: Rich - Student Pharmacist
Date published: 2012-08-10

Condition is severe. Can we give our dog 1 primor in morning and 1 at night for a couple of days?

Condition is severe. Our dog is 15 and has a life threatening situation. We administered 1 in morning & 1 at night for 2 days in a row now because conditioning was worsening by the minute. It seems to have definitely helped being that we gave our dog the 2nd dose on the 2nd day even though indications said to administer 1 in morning 1 at night on 1st day then 1 a day for next couple of days. Is this okay to continue this way? Thnx
Asked by: rick
I don't know what the condition is, nor do I know what you mean by it's worsening. What I do know is you should not give Primor unless specifically told to do so by your veterinarian. I would strongly suggest you contact your veterinarian right away if your pet is that sick.
Answered by: Gary, Dir. of Pharmacy Services
Date published: 2012-03-09

reactions to various meds

Schauzner 16 years old. Had digestion problems in past, Lately intermitent agression, diarrhea, tiredness. Vet meds were primor 20mg/1 time daily, sucralfate no mg, 1/2 twice daily, clomipraminr 25mg 1 twice daily. A late question because I lost him a few days ago--could these meds have had any bad effect on an old dog?
Asked by: issa
Each of the medications you mention have potential side effects. Side effects that may occur with Primor can include KCS or dry eye, anemia, fever, loss of appetite, vomiting or diarrhea, joint inflammation, kidney damage, or skin rash. A side effect that may occur with sucralfate is constipation. Side effects of clomipramine may include seizures; a fast or irregular heartbeat; high blood pressure; difficulty urinating; or fever with increased panting, muscle stiffness or muscle weakness; drowsiness or dizziness; dry mouth and eyes; constipation; panting; mild agitation, weakness or headache; nausea or loss of weight or appetite.
Answered by: Gary, Dir. of Pharmacy Services
Date published: 2011-11-28

why use gloves when administering

Asked by: angel
I am not aware of a caution to use gloves when administering this medication unless you have an allergy to sulfa drugs then you should probably consider using gloves.
Answered by: Gary, Dir. of Pharmacy Services
Date published: 2010-08-26

Does primor cause problems with blood sugars in diabetic dog?

Asked by: Theo
There is a remote possibility of hypoglycemia. You should be aware of your pets normal behavior and look for any signs that would indicate hypoglycemia such as weakness; depression, lethargy, sluggishness; staggering gait; behavioral changes; muscle twitching; seizures.
Answered by: Gary, Dir. of Pharmacy Services
Date published: 2009-12-31

what is the best medicine for worms in puppies

Asked by: karen
If your puppy weighs at least 6 lbs, you can use a product called Dog Worms 3. If your pet weighs less than 6 lbs, you can use Panacur C.
Answered by: Gary, Dir, of Pharmacy Services
Date published: 2009-10-08
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