Primor (sulfadimethoxine/ormetoprim) is a broad-spectrum antibiotic combination used to treat susceptible bacterial infections in dogs. Primor requires a prescription from your veterinarian, and is sold per tablet.
For: Dogs
Benefits:
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Treats skin and soft tissue infections (wounds and abscesses)
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Also effective against urinary tract infections caused by susceptible bacteria
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Single, comparatively low dose provides rapid and sustained therapeutic blood levels
How it works: Primor is made up of two antibiotics: sulfadimethoxine and ormetoprim. Together, these antibiotics are even more powerful than when they are used alone, as they block two sequential steps in bacterial folic acid synthesis. The net effect is not only the limiting of bacterial growth, but the killing of bacteria as well.
Cautions: Do not use in pregnant or nursing animals. Your pet should be encouraged to drink plenty of water while being given Primor. Before giving Primor, be sure to tell your veterinarian what other medications or treatments your pet is receiving.
More Information:
Brand Name Primor Tablets (Pfizer Animal Health)
Generic Name Sulfadimethoxine/Ormetoprim
What is the most important information I should know about Primor: Primor is a prescription medication FDA-approved for veterinary use in dogs. Primor is available as scored tablets in two strengths: Primor 240 containing 200mg sulfadimethoxine and 40mg ormetoprim, and Primor 1200 containing 1000mg sulfadimethoxine and 200mg ormetoprim. The usual initial starting dose is 25mg/pound on the first day of treatment followed by 12.5mg/pound given once a day. Treatment should continue for 2 days after symptoms disappear. However, treatment should not exceed 21 consecutive days. Always follow the dosage instructions provided by your veterinarian. Do not give Primor to any pet other than the pet for whom it was prescribed. Primor is not for use in animals allergic to it or other sulfa drugs.
What is Primor: Primor is a potentiated sulfa drug used in dogs for the treatment of skin and soft tissue infections (wounds and abscesses), and urinary tract infections caused by susceptible bacteria. Primor may also be used for other conditions not listed.
What should I discuss with my veterinarian before giving Primor to my pet: Tell your veterinarian if your pet is allergic to Primor or other sulfonamides (sulfa drugs). Tell your veterinarian if your pet has liver disease or blood dyscrasias, is dehydrated, or is pregnant or lactating. Also tell your veterinarian what other medication, including vitamins and supplements, that you are giving your pet while giving Primor.
How should this medication be given: Give this medication exactly as directed by your veterinarian. Give Primor by mouth. It may be given with food. Leave plenty of water for your pet to drink. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Primor at room temperature in a tight, light-resistant container. Keep this medication away from children and pets.
What happens if I miss giving a dose: Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.
What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include side effects listed below and may also include behavioral changes.
What should I avoid while giving Primor to my pet: Antacids may decrease the effectiveness of sulfa drugs such as Primor. Give antacids 2-3 hours before or after giving a dose of Primor.
What are the possible side effects of Primor: Sulfa crystals may appear in your pet's urine. Your pet should be allowed to drink plenty of water while taking this medication. Other side effects that may occur include KCS or dry eye, anemia, fever, loss of appetite, vomiting or diarrhea, joint inflammation, kidney damage, or skin rash. Stop the medication and contact your veterinarian if any of the above symptoms occur. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet. If your pet experiences an allergic reaction, signs may include facial swelling, hives, scratching, and sudden onset of diarrhea, vomiting, shock, seizures, or coma. If these signs occur, contact your veterinarian immediately.
What other drugs will affect Primor: Before giving Primor, tell your veterinarian if your pet is being given methotrexate, warfarin, phenylbutazone, thiazide diuretics, aspirin, probenecid, or phenytoin.
Where can I get more information: Your pharmacist has additional information about Primor written for health professionals that you may read.
Directions:
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Primor is a prescription medication used in dogs for the treatment of skin and soft tissue infections (wounds and abscesses), and urinary tract infections caused by susceptible bacteria.
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Pets should be encouraged to drink plenty of water while being given Primor. Primor may be given with food.
Tip: If your pet shows no improvement after 2 or 3 days, have your veterinarian re-evaluate your pet’s diagnosis. Treatment should not exceed 21 consecutive days.
Dosage:
Pet
Weight
Dosage
Dogs:
All weights
The initial dose is 25mg per pound of pet’s body weight on the first day of treatment followed by 12.5mg per pound of pet’s body weight given once a day thereafter. Treatment should continue for at least 2 days after symptoms disappear.
Cats:
Horses:
Storage: Store this medication at room temperature away from moisture and heat.
I have six schnauzer's. The first time I used primor on one of my schnauzer's it was used to prevent bladder stones. My poor girl developed dry eye that they say may never clear completely. She may have to have surgery to treat this. Another one of my girls was given Primor for a bladder infection. She developed nausea and diarhea(with severe bleeding) and refused to eat for six days and was severely dehydrated. She is 12 years old, and I thought for sure I was going to lose her. She is FINALLY doing better, but now I am having trouble getting her weight back up. I will NEVER use Primor again. As far as I am concerned it should be outlawed.
"Primor caused my dog to Shake and was Scared! :("
My poor Maltese, who is 6 yrs old had bladder surgery to remove a stone. 2 weeks after surgery he continue to have urges to urine. Took him to the Vet and they gave him Primor to address a new UTI. The first Dose was strong (2 tablets, 240 each). NEVERA AGAIN! My dog reacted so strange to it . My husabnd went to kiss him and he jumped out of his skin. He was shaking like a leaf. Walking around the house with his tail down. Ended up going to the emergency. They gave him a Valium IV to calm him down and had a fever of 102.9.....AWEFUL EXPERIENCE! The E.R Vet said this is an OLD Drug with too many side effects. He informed us that the newer drugs don't have as many side effect........My little guy was freaked out! I thought something was going to happen. What a scary experience! Becareful--I would hate for your dog to experience the same thing!
I had this prescribed for a uti/uterus infection that would not clear up with another antibiotic. It worked wonderful and the dog is happy and healthy now. No side effects.
My Chi. had a UTI and itchy skin. Within a week of using Primor his infection was cleared. I saw no results of it clearing his itchy skin,though. I was very scared to give this after reading the other reviews. Always read reviews and talk to your vet if you feel the need.
My dog was given primor for a rash. We had to deal with loose bowels the entire duration of the treatment. Now for no know reason my dog has been limping and protecting a paw. The second day now she has gotten worse. I thought I would check out the side effects and joint inflamation is a side effect. I suppose I'll wait to see if it passes. I don't want to take her to the vet, because I don't want her on another medicine.
Schauzner 16 years old. Had digestion problems in past, Lately intermitent agression, diarrhea, tiredness. Vet meds were primor 20mg/1 time daily, sucralfate no mg, 1/2 twice daily, clomipraminr 25mg 1 twice daily. A late question because I lost him a few days ago--could these meds have had any bad effect on an old dog?
Each of the medications you mention have potential side effects. Side effects that may occur with Primor can include KCS or dry eye, anemia, fever, loss of appetite, vomiting or diarrhea, joint inflammation, kidney damage, or skin rash. A side effect that may occur with sucralfate is constipation. Side effects of clomipramine may include seizures; a fast or irregular heartbeat; high blood pressure; difficulty urinating; or fever with increased panting, muscle stiffness or muscle weakness; drowsiness or dizziness; dry mouth and eyes; constipation; panting; mild agitation, weakness or headache; nausea or loss of weight or appetite.
I am not aware of a caution to use gloves when administering this medication unless you have an allergy to sulfa drugs then you should probably consider using gloves.
There is a remote possibility of hypoglycemia. You should be aware of your pets normal behavior and look for any signs that would indicate hypoglycemia such as weakness; depression, lethargy, sluggishness; staggering gait; behavioral changes; muscle twitching; seizures.
the dr,started ti give us Clavimox but too much $ so they gave my cat primor but it says it is for dogs not cats will it hsrm my cat she is our baby not a lab rat Please answer stst
Primor is FDA approved for use in dogs only. Primor is metabolized in the kidneys and if the pet is not properly hydrated with fluids, crystals can form in the kidneys.
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.
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