Percorten-V (desoxycorticosterone pivalate) is the only medication approved by the FDA for treating Canine Addison's Disease (hypoadrenocorticism). Percorten-V requires a prescription from your veterinarian.
How it works:
Canine Addison's Disease is a condition where a dog's adrenal glands don't work properly. Normal adrenal glands produce mineralocorticoids that help regulate many bodily functions such as metabolism, blood pressure, and stress response. Percorten-V is a replacement therapy for the mineralocorticoid deficiency in dogs with Addisons disease.
Do not use any preventative vaccines such as Percorten-V without checking with your veterinarian. Talk to your veterinarian about any side effects that seem unusual or bothersome to your pet. Percorten-V should not be stopped suddenly. Percorten-V should not be given to pregnant dogs, or dogs suffering from congestive heart disease, severe renal disease or edema.
Brand Name Percorten-V (Novartis)
Generic Name Desoxycorticosterone pivalate (DOCP)
What is the most important information I should know about Percorten-V: Percorten-V is a prescription medication that is commonly used by veterinarians in dogs for the treatment of Addison's disease. Percorten-V is available as a 4 ml multi-dose vial containing 25mg/ml. Percorten-V should not be stopped suddenly. Irritation at the injection site may occur. Percorten-V is administered IM (intramuscularly). Do not administer IV (intravenously). Contact the veterinarian if the pet develops behavior changes, swelling, or unusual weight gain.
What is Percorten-V: Percorten-V is a corticosteroid used to treat conditions in which the body does not produce enough of its own steroids, such as Addison's disease. Percorten-V may also be used for purposes other than those listed in this guide.
What should I discuss with my veterinarian before giving Percorten-V to my pet: Do not give Percorten-V to your pet if the pet has a serious bacterial, viral or fungal infection. Percorten-V weakens the pet's immune response and its ability to fight infections. Tell your veterinarian if your pet has kidney or liver disease, heart disease, stomach ulcers, hypothyroidism, diabetes mellitus or any other medical conditions. Also tell your veterinarian if the pet is pregnant or lactating.
How should this medication be given: Give this medication exactly as directed by your veterinarian. Do not give more or less than is prescribed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. The usual dose of Percorten-V in dogs is 1mg/pound given by IM injection every 25 days. Store Percorten-V at room temperature away from moisture and heat. Keep this medication away from children and pets.
What happens if I miss giving a dose: Give the missed dose as soon as you remember. However, if it almost time for the next dose, skip the dose missed and give only the next regularly scheduled dose. Do not give a double dose of this medication.
What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include swelling or water retention, high blood pressure, weight gain, low levels of potassium in the blood, and Cushing's disease.
What should I avoid while giving Percorten-V to my pet: Avoid sources of infection. Do not use any preventative vaccines without checking with the veterinarian.
What are the possible side effects of Percorten-V: If any of the following serious side effects occur, stop giving Percorten-V and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), increased blood pressure or sudden weight gain. Other less serious side effects may occur. Continue giving Percorten-V and talk to your veterinarian if your pet experiences insomnia, nausea, vomiting or stomach upset, fatigue, muscle weakness or joint pain, problems with diabetes control or increased hunger or thirst. Other side effects that occur rarely, usually with high doses of Percorten-V include thinning of the skin, cataracts, glaucoma, behavior changes. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
What other drugs will affect Percorten-V: Do not give any other over the counter or prescription medications, including herbal products, during treatment with Percorten-V without first talking to the veterinarian. Tell your veterinarian if your pet is taking Phenobarbital, furosemide, insulin or glipizide, phenytoin, digoxin, warfarin, or aspirin. Drugs other than those listed may interact with Percorten-V resulting in side effects or altered effectiveness.
Where can I get more information: Your pharmacist has additional information about Percorten-V written for health professionals that you may read.
Percoten-V is a prescription medication that is commonly used by veterinarians in dogs for the treatment of Addison’s disease.
Percoten-V is a corticosteroid used to treat conditions, such as Addison’s disease, in which the body does not produce enough of its own steroids.
Percoten-V is available as a 4 ml multi-dose vial containing 25mg/ml and is administered IM (intramuscularly). Do not administer IV (intravenously).
Tip: Percoten-V should not be stopped suddenly. Irritation at the injection site may occur.
Shake well before using. Give 1mg per pound of body weight by IM (intramuscular) injection every 25 days
Storage: Store this product at room temperature, away from moisture and heat.
Active Ingredients (per mL)
Thimerosal (a preservative)
Vino is now up to 30 day lapse between injections. He is his normal self and only taking 1/2 prednisone tablet which has made his hair stop falling out and has its sheen back. Thank you 1800PetMeds for helping to make the medication available at the lowest cost available.
Rosco was diagnosed with Addisons about 2 years ago and thanks to the Percorten-V and the Prednisone he's living a happy and healthy life He gets his shot every 30 days and 2.5 mg of Prednisone every morning he is now 7 years old Thanks you PetMeds for making his medication available every month at great price
My lab was diagnosed at 9 months old with Addison's Disease, he is going to be 9 years old in April.
Percoten V along with Prednisone saved his life and has lived a full life so far and still going strong.
This product to has helped save my dog's life. It works well and she is here because of it. Percorten is easy to draw and administer with the proper syringe for the proper dosage.
This product is a lifesaver
My dog Tela was diagnosed with Addison's early last June. Since then I have been giving her monthly injections of Percorten (1 every 28 days). I do have her electrolytes tested once a month and have been lowering her dosage slowly. Percorten has saved her life and I strongly recommend it if your dog has Addison's disease.
How much comes in a bottle of percorten? And how many doses?
1 year, 6 months ago
4 mL comes in one bottle. My dog originally got a shot of 2.4 mL when she was first diagnosed. Now I have her electrolytes tested every month and her dose is now at 1.6 mL. My vet has been dropping it by approximately .2mL a month. However, I will keep testing her electrolytes until I find out her ideal, low dosage.
1 year, 4 months ago
percorten 25mg/ml comes in a 4 ml multi use vial. If you provide the dose prescribed by your veterinarian, we will be happy to tell you how many doses in one vial. Please call us with details.
Hair growth is not a known side effect of this drug, you may obtain more information from the manufacturer to see if they have had similar reports from other people. Otherwise you should check with your veterinarian to see if there may be any other causes for the hair growth.
Thank you for the question. A little oozing of the medication is normal when a needle is pulled out from the vial. If you notice considerable amount of oozing, it could be due to improper medication drawing technique. Please ask your veterinarian to show proper medication withdrawal from the vial.
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.