Pancrezyme (pancreatic enzymes) is used to treat pancreatic insufficiency or maldigestion syndrome. It's used in pets whose bodies are not making a sufficient amount of pancreatic enzymes.
Pancrezyme requires a prescription from your veterinarian.
For: Cats and Dogs
Effective treatment for Pancreatic Insufficiency Disorder (PID)
Restores pet to healthy weight (weight loss is often associated with PID)
FDA-approved for use in cats and dogs
How it works:
Pancrezyme is a form of pancreatic enzymes normally produced by the pancreas for the purpose of digesting and absorbing fats, proteins, and carbohydrates It is used for those pets in which the enzymes are not produced naturally and in sufficient quantity.
Pancrezyme is a concentrate derived from whole raw pancreas of porcine origin, and therefore should not be given to pets allergic to pork. Pet owners should avoid inhaling the powder since it can irritate the mouth. If any of the following side effects occur, stop giving Pancrezyme and seek emergency veterinary medical attention: hives, difficulty breathing, swelling (lips, tongue, or face). Other side effects may also occur.
Brand Name Pancrezyme (Virbac), Viokase-V (Fort Dodge)
Generic Name Pancreatic Enzymes
What is the most important information I should know about Pancrezyme: Pancrezyme is a prescription medication FDA approved for veterinary use in dogs and cats. Pancrezyme is available as a powder. (For tablets, see our PancreVed product page) Each 1 teaspoonful of powder (2.8 Gm) contains Lipase (71,400 USP Units), Protease (388,000 USP Units) and Amylase (460,000 USP Units). The usual dose of Pancrezyme powder in dogs is 3/4-1 teaspoonful mixed with each meal. After mixing, allow the mixture to stand for 15-20 minutes before feeding it to the pet. For cats, the usual dose of Pancrezyme powder is 1/4-3/4 teaspoonful of the powder mixed with each meal. After mixing, allow the mixture to stand for 15-20 minutes before feeding it to the pet.
What is Pancrezyme: Pancrezyme consists of enzymes naturally produced by the pancreas necessary for the digestion of food. Pancrezyme is used as a digestive aid and as replacement therapy for inadequate digestion due to pancreatic insufficiency. Pancreatic enzymes are derived from whole, raw pancreas of pork origin. Pancrezyme may also be used for purposes other than those listed in this guide.
What should I discuss with my veterinarian before giving Pancrezyme to my pet: Tell your veterinarian if your pet has an allergy to pork. Tell your veterinarian if your pet is being given antacids such as Maalox, H2 blockers such as cimetidine or proton pump inhibitors such as Prilosec. Tell your veterinarian if your pet is pregnant or lactating.
How should this medication be given: Give this medication exactly as directed by your veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. The pet owner should avoid inhaling the powder as it might irritate the mouth. Pancrezyme should be given with food. Mix the powder with the pets food and let stand for 15-20 minutes before feeding the pet. Store Pancrezyme at room temperature away from moisture and heat. Keep this medication away from children and pets.
What happens if I miss giving a dose: Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.
What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of Pancrezyme overdose may include diarrhea, excess fat in the feces, increased appetite, and weight loss.
What should I avoid while giving Pancrezyme to my pet: Pancrezyme should not be given to pets allergic to it, or to pets allergic to pork. The pet owner should avoid inhaling the powder as it might irritate the mouth.
What are the possible side effects of Pancrezyme: If any of the following serious side effects occur, stop giving Pancrezyme and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips; tongue or face; hives). Continue giving Pancrezyme and talk to your veterinarian if your pet experiences diarrhea or loose stools. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
What other drugs will affect Pancrezyme: Tell your veterinarian if your pet is being given antacids such as Maalox, H2 blockers such as cimetidine or proton pump inhibitors such as Prilosec. Drugs other than those listed may also interact with Pancrezyme. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines.
Where can I get more information: Your pharmacist has additional information about Pancrezyme written for health professionals that you may read.
Pancrezyme is a digestive aid for pets with pancreatic insufficiency or maldigestion syndrome. It is a prescription medication used in dogs and cats and is available in powder form. (For tablets, see our PancreVed product page)
Pancrezyme consists of enzymes naturally produced by the pancreas necessary for the digestion of food.
Pancreatic enzymes are derived from whole, raw pancreas of pork origin.
Tip: The pet owner should avoid inhaling powder as it might irritate the mouth.
Give 3/4-1 teaspoonful of the powder thoroughly mixed in with each meal. After mixing, allow the mixture to stand for 15-20 minutes before feeding it to the pet
Give 1/4-3/4 teaspoonful of the powder thoroughly mixed in with each meal. After mixing, allow the mixture to stand for 15-20 minutes before feeding it to the pet
Storage: Store this product at room temperature, away from moisture and heat.
Ingredients (per teaspoon)
Lipase 71,400 USP units
Protease 388,000 USP units
Amylase 460,000 USP units
Esterases, peptidases, nucleases and elastase.
Pancrezyme saved our dog's life
Our 10-year-old German Shepher/Lab mix dog started losing a LOT of weight, ravenously hungry, and having really runny "cowpile" stools. She was diagnosed with EPI and we started using Pancrezyme. Within 2 weeks, we could see the weight going back on her and her old zip was back. Great product, simple to use, and it works. PetMeds is wonderful about sending the product so quickly when we need it.
Life saving product!
Zoe is a German Shepherd. She was 2 years old when she was diagnosed with EPI. She is now 4 and we have been using the Pancrezyme powder since then and haven't looked back. As long as the enzymes are on her food she never has any problem digesting her food. Nobody can believe that she has this disease. because she looks so healthy. Just wish the price wasn't so high as we go through the largest bottle of powder in one month.
This has been a miracle !!!! In one day a difference in
my dogs stool. She is more content and now just
waiting for the weight she has lost to start returning.
I must admit next month I am trying a generic brand
because I need a product under $ 100 a mo.
Chow, Female.......diagnosis EPI at 6 months old... now almost 5 yrs. old. Absolutely recommend VIRBAC Pancrezyme.... will not use any other Brand!. Excellent Results!!!
This enzyme saved my dogs life! He was losing weight very quickly because he was unable to digest his food.since starting this prescription , Yoda has regained weight and energy! Awesome stuff!
Pearl is a pound rescue I adopted. Husky GS mix. Currently weighs 46lbs. Had Parvo right after being rescued, eats her own poo and has had diarrhea for 3 months now. She also has extreme hip dysplasia. Poor thing. Anyway she has been on metronidazole. I just started the enzymes yesterday. I am using 1/2 teaspoon. Mix it in wet food and then put it on top of dry. Then let it sit 15 to 20 minutes before feeding. Is that a good enough amount?
16 lb Westie Malaki Pancrezyme was started 6 days ago . Good results ,diarrhea stopped , energy back ,Malaki is experiencing bad breath and odor is this normal ? After reading this site we realized we were not waiting 15 to 20 minutes before feeding, could that cause a problem ?
11 months ago
New Smyrna Beach FL
yes, if you were not waiting the 15 to 20 minutes before feeding....that could be the culprit. You should notice an improvement now that you are using it correctly. If you dont, please notify your vet to make sure there is no issue with the dog's gums.
My dog has been using Pancrezyme mixed with water and incubated 20 minutes on food before eating. His mouth lining way back in the cheeks are sore. What keeps the activated enzymes that stay in the mouth caught in cheek areas from starting to eat the lining of the dogs mouth? I give him extra broth with water afterwards but he uses enzymes 3 times a day. I am worried about his gums getting in poor shape and hence his teeth.
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.