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Metoclopramide


 
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  Product Info   How to use   Ingredients   Customer Reviews   Q & A  

What is Metoclopramide?

Metoclopramide is used to treat nausea, vomiting, and reflux disease in dogs and cats by normalizing their digestive system function. Metoclopramide requires a prescription and is sold per tablet.
For: Cats and Dogs
 
Benefits:
Affordable
Easy to administer

How it works:
When motility (movement) in the stomach is reduced, food pools and creates a sensation of nausea and bloating. In some cases, bile refluxes from the intestine back into the stomach, causing irritation and more nausea. Metoclopramide normalizes stomach contractions so that food and bile can pass in the correct direction. Additionally, metoclopramide is able to cross a biochemical blood-brain barrier to control nausea. Metoclopramide helps the vomiting pet by acting directly on the brain to reduce the sensation of nausea.

Cautions:
Do not use a monoamine oxidase inhibitor (MAOI) such as Anipryl, Selegiline, or a Preventic Flea Collar on your pet while giving this medication. Stop giving metoclopramide and contact your veterinarian immediately if your pet has an allergic reaction. Tell your veterinarian if your pet has kidney disease, diabetes, or high blood pressure, if your pet has had recent stomach surgery, or is pregnant or lactating.


More Information:
Brand Name
Reglan (Robins)
Generic Name
Metoclopramide (me-toe-klo’-pra-mide)

What is the most important information I should know about metoclopramide:Metoclopramide is a prescription medication that is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to use this medication in dogs and cats. Metoclopramide is available as 5mg and 10mg scored tablets. The usual dose for dogs and cats is 0.1-0.2mg/pound every 6-8 hours. Always follow the dosage instructions provided by your veterinarian. Metoclopramide is not for use in animals allergic to it. Call your veterinarian immediately if your pet exhibits uncontrollable movements or muscle spasms of the legs, lips, jaw, tongue, face or other body part, agitation, jitteriness, shortness of breath or insomnia. Metoclopramide may cause drowsiness.

What is metoclopramide: Metoclopramide is a gastrointestinal stimulant used in the treatment of nausea, vomiting, and esophageal reflux. It also used to treat post-operative nausea and vomiting and to prevent nausea and vomiting associated with cancer chemotherapy. Metoclopramide may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving metoclopramide to my pet: Tell your veterinarian if your pet has kidney disease, diabetes, high blood pressure or recent stomach surgery. Inform your veterinarian if your pet is pregnant or lactating.

How should this medication be given: Metoclopramide is usually given 3 or 4 times a day. Give each dose with plenty of water. Follow your veterinarian¿s instructions. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store metoclopramide at room temperature away from moisture and heat. Keep this medication away from children and pets. 

What happens if I miss giving a dose: Give the missed dose as soon as you remember during the same day. However, if you don¿t remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include drowsiness, confusion, and uncontrollable movements of the legs, face and tongue, muscle spasm of the neck, tremor, irritability and agitation.

What should I avoid while giving metoclopramide to my pet: Do not use Preventic Flea Collar on your pet while giving this medication.

What are the possible side effects of metoclopramide: Stop giving metoclopramide and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives), uncontrollable spasms of the legs, lips, jaw, tongue, face or other body part, anxiety, agitation, insomnia, depression, yellowing of the skin or eyes, seizures. Other less serious side effects that may occur include nausea or diarrhea, dizziness, drowsiness, confusion, fluid retention, increased urination. Continue to give the medication and contact your veterinarian.

What other drugs will affect metoclopramide: Before giving metoclopramide, tell your veterinarian if your pet is being given an MAOI such as selegiline or Anipryl (within the last 14 days), digoxin, cyclosporine, tetracycline, insulin, a narcotic pain reliever or anticholinergic or antispasmodic medications such as Bentyl (dicyclomine). Also tell your veterinarian of any other medications you are giving that may cause drowsiness such as pain relievers, anxiety medications, muscle relaxants or any other prescription or over the counter medications. 

Where can I get more information: Your pharmacist has additional information about metoclopramide written for health professionals that you may read.

 

Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.

Directions:

Metoclopramide is a prescription medication used to treat nausea, vomiting, and reflux disease in dogs and cats.
Metoclopramide is also used to treat post-operative nausea and vomiting and to prevent nausea and vomiting associated with cancer chemotherapy.

Tip: Give each dose with plenty of water. Give exactly as directed by your veterinarian.
Dosage:
Pet Weight Dosage
Dogs/Cats: All weights The usual dose is 0.1–0.2mg per pound of pet’s body weight every 6–8 hours
Horses:
Storage: Store at room temperature, away from moisture and heat.
Metoclopramide (5 mg):
Active Ingredients (per tablet)
Metoclopramide 5 mg
Other Ingredients:
Anhydrous lactose, Magnesium Stearate, Povidone, Pregelatinized Starch, Sodium Starch Glycolate, D&C Yellow #10, and FD&C Blue #1.

Metoclopramide (10 mg):
Active Ingredients (per tablet)
Metoclopramide 10 mg
Other Ingredients:
Anhydrous lactose, Magnesium Stearate, Povidone, Pregelatinized Starch, Sodium Starch Glycolate, D&C Yellow #10, and FD&C Blue #1.

Metoclopramide (250 mg):
Active Ingredients (per tablet)
Metoclopramide 250 mg
Other Ingredients:
Anhydrous lactose, Magnesium Stearate, Povidone, Pregelatinized Starch, Sodium Starch Glycolate, D&C Yellow #10, and FD&C Blue #1.

Metoclopramide (500 mg):
Active Ingredients (per tablet)
Metoclopramide 500 mg
Other Ingredients:
Anhydrous lactose, Magnesium Stearate, Povidone, Pregelatinized Starch, Sodium Starch Glycolate, D&C Yellow #10, and FD&C Blue #1.

Metoclopramide 4.5 5 11 11
Finally Success When my mom passed away I inherited her cat and she would eat and immediately vomit up the food before it had time to be digested. I had every test done and we finally tried metoclopramide which worked immediately. I give her a one quarter of a 5mg pill before each meal. I put the pill in a chicken pill pocket for ease of giving. As we know it's not easy giving pills to cats. I do suggest giving three small meals a day as my cat can not handle large meals and seems to like always having some food in her stomach. I feed her at 7am, 4pm and some before I go to bed. The few times I didn't give her the pill she threw up so I know this pill works. The food I feed her is Physician's diet dry food. " Venison and Green Pea. I do think the type of food you feed is important to their digestion. I hope this helps. I know how helpless I felt till we found this pill. 03/23/2012
Probably life saver After taking a month to get our Vet to give the OK for the prescription we requested from you, Dante has shown great improvement. She's an old dog and still brings up phlegm occasionally but her quality of life has markedly improved. We were about to give her the last kindness! 04/09/2011
Worked wonders for our dog This stuff has been a miracle drug for our 8.5 year old Chow/Shepard mix. We have had her since she was a puppy, and for the first year of her life she was normal, but one day she started vomiting for no apparent reason. We spent years, and THOUSANDS of dollars at multiple different vets to try to figure out what the problem was but nobody could diagnose it. The general consensus was that it was nothing life threatening (since she had been vomiting every night for most of her life no matter what food she eat) and not to worry too much. Easy for someone else to say, when they don't have to clean up dog puke EVERY day. Finally, after ingesting some contaminated water shortly after we moved to Tegucigalpa, Honduras, the vet recommended Clopofar (local equivalent) and we haven't looked back. Our almost 9 year old girl is a puppy again! She is 100% happier, more playful, and no longer underweight. We are absolutely thrilled. 02/04/2011
Miracle Drug I have an 19yr old Beagle mix that just had his teeth pulled, and he became sick afterwards, started vomiting and was constipated and flatulent. I took him to the vet, who can him an injectable of metoclopramide, and he is running around, jumping, playing, eating, and acting like a 2yr old puppy!!! This is a miracle drug! Great stuff, and I highly recommend it!! 01/25/2011
together with small amounts of food metoclopramide seems to work. simon, my cat, used to throw up on a daily basis. since he is given a quarter of the 20 mg pill AND i monitor his quantity intake all seems to be well. i also found that giving him finely ground fancy feast (instead of chunky) helps his digestion trememdeously. 07/31/2010
24 Questions · 33 Answers

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2 months ago
by
pearl
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Answer: 
Pearl,

Thank-you for your question. First, double check that the liquid solution is 5mg/5ml. If this is correct, a dosage of 0.9ml is appropriate for a dog weighing 4 pounds. Give the medication as instructed by your veterinarian. This medication is typically used as needed every 6-8 hours. Hope this helps!

Jessica A.
Pharmacy Intern
1800Petmeds
1 month, 3 weeks ago
by
Dulcineas17
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2 months ago
by
rudytutu
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Answer: 
Rudytutu,

Thank-you for your question! Metoclopramide is typically dosed 0.1-0.2mg per pound every 6-8 hours as needed. A 0.9mg dose is okay for your 4 pound dog. The tablets are only available as 5mg and 10mg, which would make dosing for your dog very difficult,if not impossible. It will be much easier to give the correct dose in a liquid form (a little less than 1ml per dose). They are the same medication, just different strengths/dosage forms. The tablets are much easier to use when dosing in larger dogs. Hope this helps!

Jessica A.
Pharmacy Intern
1800PetMeds
2 months ago
by
Dulcineas17
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can the 5mg pill be given or does it have to be liquid form?
3 months, 1 week ago
by
roxiefoxie08
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Answer: 
The usual dose for dogs and cats is 0.1 to 0.2mg per pound every 8 to 12 hours. The liquid may be necessary to obtain a small dose. Unfortunately, we do not compound Metoclopramide liquid. Consult your veterinarian for the appropriate dose and how to obtain the medication.
3 months, 1 week ago
by
Lisa M
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6 months ago
by
Anonymous
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Answer: 
For pets with nausea, a newer product is a available on the market called Cerenia. Cerenia does not have any restrictions in regards to breeds that possess the MDR1 gene. Please consult with your veterinarian to discuss the use of Cerenia for your pet.
6 months ago
by
Lilli Pharmacist
Pompano Beach, FL
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My 4 year young 15 lb Min Pin Mix was prescribed Metoclopramide for GERD 7 days ago. The dosage is 5 mg 30 minutes before each meal (twice a day). It was prescribed to control the GERD and stop the occasional vomiting (usually in the morning). The medication worked great. However, the day after starting the medication, my dog began drinking more water and had to go out more often. This did not concern me because I knew this was a known side effect. What did concern me is that my dog also had weakening of his anal sphincter muscle. Thankfully, he did not have an accident in the house, but while being walked the sphincter muscle would relax and sometimes a small amount of stool would just fall out as he was walking (not squatting). This went on every day for an entire week. The vet assured me that it was NOT the Metoclopramide that was causing this. However, after my dog urinated in his sleep, I stopped giving him the Metoclopramide. One day later (yesterday), the fecal and urinary incontinence stopped. It is glaringly obvious that the Metoclopramide caused these problems. According to your dosage instructions, a 15 lb dog should get 1.5 to 3 mg per dose. Was the 5 mg the vet prescribed too much? Do you think a lower dosage would work without causing the problems I noted above?
Thank You
11 months ago
by
Vought
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Answer: 
you have a good point.....the dose of 1.5 to
3 mg which is the usual dose...may be
completely adequate.......Since the tablet comes 5mg ( and is scored )....a dose of
2.5mg sounds very reasonable. However
I am not a prescriber and I am not questioning the vet's judgement.......My advice would be to let the vet know you are going to try the 2.5 mg dose and determine if it works well and has no adverse effects.
11 months ago
by
Linda M 1800petmeds pharmacist
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Product Q&A

24 Questions | 33 Answers
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
 
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