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Methimazole


 
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  Product Info   How to use   Ingredients   Customer Reviews   Q & A  

What is Methimazole?

Methimazole is used to treat hyperthyroidism in cats. It has largely replaced propylthiouracil in this treatment process since it has a lower incidence of adverse side effects. Methimazole requires a prescription from your veterinarian, and is sold per tablet.
For: Cats
 
Benefits:
Effectively treats hyperthyroidism in cats
Rapid results
Affordably sold per tablet

How it works:
Hyperthyroidism is a condition that occurs when the thyroid gland produces too much thyroid hormone. Methimazole inhibits the production of thyroid hormones.

Cautions:
Blood tests must be done to check for proper dosage. Do not use in pregnant or nursing animals. Do not give your pet a live vaccine while giving methimazole. Contact your veterinarian immediately if your pet develops signs of an infection.


More Information:
Brand Name
Tapazole (Jones)
Generic Name
Methimazole

What is the most important information I should know about Methimazole: Methimazole is a prescription medication not FDA approved for veterinary use; however, it is a commonly accepted practice for veterinarians to use this medication in cats. Methimazole is available as a 5mg scored tablet. The usual initial dose for cats is 5mg every 8 to 12 hours. Do not give methimazole to pregnant or nursing animals. Methimazole can increase the risk of bleeding. Methimazole can lower the blood cells that help fight infections. Your veterinarian will need to give blood tests on a regular basis to be sure these blood cells do not get too low. Do not give the pet a "live" vaccine while the pet is taking methimazole. Methimazole is needed for the life of the pet. If the medication is stopped, the symptoms will reappear.

What is Methimazole: Methimazole prevents the thyroid gland from producing too much thyroid hormone. Methimazole is used to treat overactive thyroid (hyperthyroidism). It is also used before thyroid surgery or radioactive iodine treatment. Methimazole may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving Methimazole to my pet: Tell your veterinarian if your pet has an allergy to methimazole or if your pet has liver disease, a blood cell disorder, or a weak immune system. Tell your veterinarian if the pet is pregnant or nursing. Inform your veterinarian of any other medications, including vitamins and supplements your pet may be taking while receiving methimazole.

How should this medication be given: Give this medication exactly as directed by your veterinarian. Do not give in larger amounts, or give it for longer than recommended by your veterinarian. Follow the directions on the prescription label. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Methimazole can be given with or without food. Allow plenty of water for the pet to drink. Store methimazole at room temperature away from moisture and heat. Keep this medication away from children and pets. 

What happens if I miss giving a dose: Give the missed dose as soon as you remember during the same day. However, if you don¿t remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of methimazole overdose may include nausea, vomiting, upset stomach, joint pain, headache, fever, itching, swelling, and easy bruising or bleeding.

What should I avoid while giving Methimazole to my pet: Do not give the pet a "live" vaccine while the pet is taking methimazole. Contact your veterinarian at once if your pet develops signs of an infection.

What are the possible side effects of Methimazole: If any of the following serious side effects occur, stop giving methimazole and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips; tongue or face; hives). Stop giving methimazole and contact your veterinarian at once if your pet develops any of these serious side effects; fever, chills, body aches; easy bruising or bleeding, unusual weakness; blood in the urine or stools; severe blistering, peeling, and skin rash; nausea, low fever, loss of appetite, dark urine, jaundice. Other less serious side effects may occur. Continue giving methimazole and talk to your veterinarian if your pet experiences headache, drowsiness, dizziness; mild nausea, or vomiting; itching; muscle, joint, or nerve pain; swelling; hair loss. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

What other drugs will affect Methimazole: Tell your veterinarian if your pet is taking theophylline (Theo-Dur), warfarin (Coumadin), digoxin (Lanoxin), a beta blocker such as atenolol (Tenormin), metoprolol (Lopressor), or propranolol (Inderal). Drugs other than those listed may also interact with Methimazole. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines.

Where can I get more information: Your pharmacist has additional information about methimazole written for health professionals that you may read.

Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.

Directions:

Methimazole is a prescription medication used by veterinarians to treat overactive (hyper) thyroid in cats.
Methimazole is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to prescribe this medication for cats.
Methimazole is also used before thyroid surgery or radioactive iodine treatment.
Periodic blood tests will be necessary while the cat is taking this medication.

Tip: Do not use in pregnant or nursing animals. Methimazole can be given with or without food.
Dosage:
Pet Weight Dosage
Cats: All weights The usual initial dose varies from 2.5-5mg 2 or 3 times a day. Periodic blood testing is required to monitor liver function and for any toxic effects on blood cells
Dogs:
Horses:
Storage: Store methimazole at room temperature, away from moisture and heat.
Methimazole:
Active Ingredients (per tablet) Amount

Methimazole

5 mg
Other Ingredients:
Lactose Monohydrate, Povidone, Talc, Croscarmellose Sodium, Magnesium Stearate, Corn Starch.
Methimazole 4.6 5 96 96
she is doing well on it As much as I do not like drugs, I can say Kiwi is doing well on it...she has gained weight and spry. She is 16 this year and still acting like a younger cat, so far. I would recommend this, as I have seen the improvement it brings with two cats, now 03/06/2014
Amazing changes Jack lost several pounds; he look frail and his coat was flat. Methimazole allows him to keep weight on. It has improved his coat. He is healthy and looks handsome, just like his old self! 01/11/2014
Excellent fast acting med My brother Boo was losing weight, grumpy as all get out (to ME, imagine, the soul of sweetness) and losing weight. Our owners took him to the vet and he has gained weight, is his usual self (he's bore) and he looks almost as gorgeous as I do -- but that is impossible! 01/04/2014
Works great At the end of August, my cat Candy was diagnosed with Hyperthyroidism. Her thyroid level was 4X what it should be, she had lost 2.5lbs. she had elevated liver enzymes & a heart murmur. After six weeks on Methimazole 1/2 a pill every 12hrs. Candy's thyroid level & liver enzymes are back down to normal, she gained back the 2.5lbs. she lost & her heart murmur is gone. Candy looks great & is acting like her old self. My vet was shocked by how quickly she responded to treatment. I use pill pockets Candy loves the taste & that makes giving her the medication much easier for me. 11/09/2013
Very successful My cat, Twtan, was an indoor-outdoor cat, before we got a dog last May. He then took a great dislike to coming back to the house when the dog never went away (in his experience, visiting dogs all eventually went home! But this one didn't! As a result, Twtan went rogue, and refused to come home, although we once caught him and brought him home - he was ravenous. Neighbors were asked NOT to feed him(which they'd done) in the hopes that the cat would return. NO such luck. Eventually caught him and found he was just a bundle of bones with fur - so thin. Ate like a horse, but put on no weight. Took him to the vet and found he had severe thyroid condition, and had gone down from 11lbs, to under 7. Given this med (5 mg.3x a day) and it soon began to work wonders. Now down to 2x a day and cat has regained his weight and fur looks great. By the way, I use a "pill popper" plunger device to get the pill to the back of his throat, and it works great. Heartily recommend it. Saves me from scratches and saves having to buy Pill Pockets or suchlike. Cat doesn't care for it but puts up with it. Used to wrap him in a towel to stop him wriggling, now no need. Thanks, Methimazole! 10/20/2013
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100 Questions · 136 Answers

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1 answer

tapazole 5 mg

I am to give my cat a half a pill of tapazole 5mg every 12 hours which is 2 times a day. I gave it to him about 45 minutes early can he have a reaction due to giving it to him early. I ask because we set our clocks ahead today and usually I give it to him at 6am and 6pm so this morning it would technically have been like at 5:15 am. He vomited 6 hours after taking the pill 2 times. I did call an emergency vet and they said that it probably wasn't the meds but I wanted to check with you. What are the guidelines as far as following the dosage time exactly. Can it hurt if given an hour early even though my vet said every 12 hours.I don't plan on doing this again but then we have the time changes it messes things up a bit.
1 month ago
by
Diane Floyd
Columbia Pa
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Answer: 
No , it wont hurt to give it a little bit early.
1 month ago
by
Linda M 1800petmeds pharmacist
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My cat was on Methimazole for about a month. She stopped eating and drinking and when the vet ran tests, discovered she was in kidney failure. After 11 days of fluids, meds, etc. she did bounce back, however I haven't put her back on the Methimazole as I'm afraid it caused the kidney failure. Vet says "no" it was most likely a bacterial infection. What do you think?
2 months, 1 week ago
by
KittyKattLover
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Answer: 
What the vet is saying makes sense. If you do not treat your cats hyperthyroidism, the end result could likely be more kidney damage. Its unlikely that the methimazole caused kidney failure, if
anything, it will help preserve kidney function and even possibly reverse some damage.
I recommend having more discussion with your vet to explain the pros and cons of treating
hyperthroidism. Perhaps you can obtain a second opinion to help you decide what is best for your pet. Also, do your own research on the matter. Good luck to you and your pet !!
1 month, 3 weeks ago
by
Linda M 1800petmeds pharmacist
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Previously you said it wasn't available, but it's been over a year, so I thought I'd ask again, even though I don't see it online. I'm currently getting 2.5mg coated tablets of felimazole through my vet, but I'm hoping to find an online resource (to save both time and money).
User submitted photo
5 months, 2 weeks ago
by
winegirl1973
Chicago
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Answer: 
If you can use the uncoated tabs,they can be broken in half. Not sure if that would be a nuisance every day, but I know I have broken the 5 mgs in half sometimes to hide them better in our cat's food.
3 months ago
by
Jack the cat
Syracuse, NY
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Answer: 
we carry methimazole 5 mg tablets only. We also offer the methimazole compounded in
a transdermal gel to be applied to base of the ear...or a methimazole chew tablet. Please call
us to find out prices. Thank You.
5 months, 1 week ago
by
Linda M 1800petmeds pharmacist
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Cat has been losing weight, hungry all the
time, using the cat pan all the time, and
vocalizing alot. After the first few days
the cat was acting more normally. Now he
is still losing weight, using the kitty pan alot,
and hungry all the time.
6 months ago
by
Nana
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Answer: 
Your veterinarian may want to reevaluate your pet to see if it is necessary for your pet to be on the medication long term. Contact your veterinarian if your pet's condition has not improved.
6 months ago
by
Cheryl-Pharmacist
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1 answer

Meds comparison

What is the difference between Methimazol & Tapazol? Is one med & other generic & actually the same?
11 months ago
by
L'il Debi
West Palm Beach, FL
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Answer: 
Methimazole is the generic available on the market for the brand drug Tapazole
11 months ago
by
Lilli Pharmacist
Pompano Beach, FL
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This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
 
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