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Lactulose Solution

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  Product Info   How to use   Ingredients   Customer Reviews   Q & A  

What is Lactulose Solution?

Lactulose is used in cats and dogs as a laxative. Lactulose requires a prescription from your veterinarian.
For: Cats and Dogs
Liquid is easy to administer
No restrictions on food, drink, or activity unless otherwise directed by the veterinarian.

How it works:
Lactulose is a disaccharide sugar composed of galactose and fructose. Unlike other sugars, its not absorbed into the blood. It passes unchanged to the large intestine. In the large intestine, lactulose is broken down by bacteria, resulting in the production of various acids. These acids draw water into the colon, softening the stool and increasing the volume, resulting in a laxative effect.

Side effects of lactulose include symptoms of flatulence, bloated stomach, and cramping. Diarrhea and dehydration are symptoms of overdose. Tell your veterinarian if your pet is diabetic, or pregnant or lactating.

More Information:
Brand Name
Chronulac or Cephulac (Hoeschst-Marion Roussel), Constulose or Enulose (Alpharma)
Generic Name
Lactulose (lakí-chew-lows)

What is the most important information I should know about Lactulose: Lactulose is a prescription medication that is not FDA approved for use in animals; however, it is a commonly accepted practice for veterinarians to use lactulose in dogs and cats as a laxative. Lactulose is available as a 10 Gm/15ml liquid. The usual laxative dose in dogs and cats is 1 ml per 2 pounds of body weight given every 8 hours initially, then use as needed. Notify the veterinarian if the pet develops excessive diarrhea.

What is Lactulose: Lactulose is a type of sugar (disaccharide) that is broken down into mild acids in the end part of the intestinal tract or colon. These acids cause water to be drawn into the colon and this water helps soften the stool. Lactulose is used to treat constipation. Lactulose may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving lactulose to my pet: Tell your veterinarian if your pet is diabetic. Tell your veterinarian if your pet is pregnant or lactating.

How should this medication be given: Give this medication exactly as directed by your veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Lactulose may be mixed with fruit juice, water, or milk to improve the taste. It may take 24 to 48 hours before the effects of lactulose are seen. Lactulose may darken slightly in color. This change is harmless. However, if lactulose becomes very dark or uneven in consistency do not use the product. Store lactulose at room temperature, away from moisture and heat. Keep this medication away from children and pets. 

What happens if I miss giving a dose: Give the missed dose as soon as you remember. However, if is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.

What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of lactulose overdose are unknown but diarrhea, abdominal cramping, and possible complications of dehydration from excessive diarrhea are possible.

What should I avoid while giving Lactulose to my pet: There are no restrictions on food, drink or activity unless otherwise directed by the veterinarian.

What are the possible side effects of Lactulose: If any of the following serious side effects occur, stop giving lactulose and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips; tongue or face; hives). Other less serious side effects may occur. Continue giving lactulose and talk to your veterinarian if your pet experiences flatulence, abdominal cramps, diarrhea or nausea and vomiting. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

What other drugs will affect Lactulose: Tell your veterinarian if your pet is being given an antacid as this may decrease the effects of lactulose. Drugs other than those listed may also interact with Lactulose. Talk to your veterinarian before giving your pet any prescription or over the counter medicines.

Where can I get more information: Your pharmacist has additional information about Lactulose written for health professionals that you may read.


Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.


Lactulose Solution is a prescription medication used in dogs and cats as a laxative.
Lactulose is also used to reduce blood ammonia levels in the prevention and treatment of hepatic encephalopathy.
Lactulose Solution is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to prescribe this medication for dogs and cats.
Because Lactulose is a type of sugar (disaccharide) tell your veterinarian if your pet is diabetic.
Antacids may decrease the effects of Lactulose.
Tip: Lactulose may be mixed with water or milk to improve the taste. It may take 24 to 48 hours before the effects of Lactulose are seen. Notify your veterinarian if your pet develops excessive diarrhea.
Pet Weight Dosage
Dogs/Cats: All weights The usual does is 1 ml for every 2 lbs of pet's body weight every 8 hours to start, or as directed by your veterinarian, then use as needed
Storage: Store at room temperature, away from heat and moisture.
Lactulose Solution:
Active Ingredients (per 15 mL) Amount
Lactulose 10 g
Lactose Less than 1.6 g
Other sugars Less than 1.2 g
Lactulose Solution 4.8 5 58 58
GREAT PRODUCT...GREAT PRICE My HORSE is a slender 15.5./16 pound cat. He was a throw-away when we discovered him bawling pitifully in our yard late fall when he was about 10 months old...14 years ago. He was a bag of bones and couldn't even eat regular food...we had to give him pablum and baby food to get him started eating. He has always had larger, dry stools but about 3 months ago he really started struggling. He could barely go and became slightly distended. He actually got almost totally bound up, That necessitated a trip to the vet with an overnight stay that included 3 enemas. Poor guy. She put him on 1 ml of Lactulose twice a day. He didn't realy enjoy having to drink it so we mix half a ml in two feedings of soft food morning and night. This stuff works wonderfully. He goes much easier and his stools are a little less large, but then he is a big boy. I was delighted to find it at PetMeds at considerably less cost then the vet charges as he will remain on it the rest of his life. We are so blessed to have caught this before it became megacolon and to find it at a reasonable cost here at PetMeds. I surely does work. 03/19/2011
Gets the job done Our big cat with mega colon hates Lactose and puts up a fight (with claws), when administered orally, but it really gets the job done. He doesn't eat it if mixed with food. We told him it was either this stuff or his life was going to be short-lived. It takes 2 of us to administer 6 cc daily. Without Lactulose solution, he would be totally blocked. He's 9 years old - acts like a kitten when he's regular - and really a loving and precious guy. I'm so greatful for this product, which I understand is safe for long-term use. I rate this product "5" for effectiveness, but not for taste (sweet syrup) and ease of use. 08/22/2014
My (rescue) Lab Maggie has hepatic encephalopathy due to a damaged liver of unknown causes-- so her liver can no longer process protein, therefore the ammonia levels build up in her blood causing life threatening problems-- after a week in the ER hospital it now is under control with diet and 2 to 3 doses of lactulose daily to remove the ammonia. I am very happy with the results, she will have to remain on this medication for the rest of her life, thank goodness it is working for her and doing exactly what it is suppose to do-- I definitely recommend this product for this problem. 07/22/2014
Best product I've ever used! Little Bitz is a rescue cat who would not be alive without this medication. It's so easy to mix in with his food that he doesn't even know it's there. This has kept him happy and very healthy for 4 years now. We tried other products but this is by far the most efficient and convenient. 07/05/2014
Lactulose really helps! My cat Skunky is 14 years old. She developed cirrhosis of the liver several years ago. As long as she takes her Lactulose once a day, she does well. If she experiences difficulty, I give her an extra dose in the evening. She also had diabetes, but it has been cured due to her high protein diet. She acts like a kitten now. 05/11/2014
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25 Questions · 47 Answers

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How many cc's would one give to 3 year old 6 lb. Mi-Ki?

Lactulose, liquid, gold in color and thick like a pancake syrup
2 months, 3 weeks ago
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Only your veterinarian can prescribe the amount of lactulose to give your pet.
2 months, 2 weeks ago
Kelly P
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1 answer


Is this version (the one sold on 1800petmeds) unflavored?
The version I got from my vet is pina colada flavored which is not great for cats.
4 months, 1 week ago
Brooklyn, NY
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This product does not have any particular flavoring.
3 months, 4 weeks ago
Lilli Pharmacist
Pompano Beach, FL
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Under what conditions would Lactuose be given to a cat for an extended amount of time? Possibly on a permanent basis?
2 years, 2 months ago
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Yes, Lactulose can be given to a cat on a permanent basis. My four year old cat will have to take Lactulose for the rest of her life.
This was per my vet. If I stop the medicine, the problem will reoccur. She has cronic constipation. Make sure to give your cat a dosage recommended by your vet.
1 year, 11 months ago
Noelle's Mom
Chicago, IL
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Lactulose may be given on a maintenance basis with conditions causing chronic constipation. Your veterinarian will determine the length of therapy based specifically on your pet.
2 years, 2 months ago
Lisa M
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2 years, 7 months ago
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The Lactulose that I get from PetMeds is not any different from the type that you would get from a pharmacy for people. I have had this medication from my doctors prescription for constipation and found out from him that it's the same stuff, just that the pharmacy dispense it in smaller quantities.
User submitted photo
1 year, 9 months ago
New Jersey
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The lactulose sold for pets is the human use product. Electrolyte disorders such as hypercalcemia are usually associated (in humans) with excessive doses of the medication.
2 years, 7 months ago
Gary, Pharmacist
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2 years, 8 months ago
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Lactulose only comes in one strength (10mg/15ml)... There are different manufacturer's who may use different inactive ingredients but the active drug remains the same.
2 years, 8 months ago
Janine, Pharmacist 1800PetMeds
Pompano Beach, Florida
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This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
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