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Ketoconazole


 
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  Product Info   How to use   Ingredients   Customer Reviews   Q & A  

What is Ketoconazole?

Ketoconazole is used to treat fungal infections. It is also used to treat Cushing's disease. Ketoconazole, available as 200mg scored tablets (sold per tablet), requires a prescription from your veterinarian.
For: Cats and Dogs

Benefits:
Treats various internal and external fungal infections
Easy to administer

How it works:
Ketoconazole is an antifungal medication that blocks the formation of cortisol in the adrenal glands and for that reason is used in the treatment of Cushing’s disease.

Cautions:
Ketoconazole can interact with many other drugs. Fully disclose to your veterinarian any medications your pet is taking before giving ketoconazole. Do not use in pregnant or nursing animals.


More Information:
Brand Name
Nizoral (Janssen)
Generic Name
Ketoconazole (keet-ah-coneí-ah-zole)

What is the most important information I should know about ketoconazole: Do not give this medication if your pet is taking astemizole (Hismanal), cisapride (Propulsid) or triazolam (Halcion). Combined with these drugs, ketoconazole could cause serious, even fatal side effects. In rare cases, ketoconazole can cause severe liver damage. Notify your veterinarian immediately if your pet develops nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, yellow eyes, itching, or dark urine. These symptoms may be early signs of liver damage.

What is ketoconazole: Ketoconazole is an antifungal medication. Ketoconazole is a prescription medication that is not FDA approved for use in animals; however, it is a commonly accepted practice for veterinarians to use this medication in dogs and cats to treat various internal and external fungal infections. Ketoconazole is also used to treat Cushing¿s disease. Ketoconazole is available as 200mg tablets. The usual dose of ketoconazole for dogs and cats is 2.2-13mg/pound every 12 to 24 hours, depending on the disease being treated.

What should I discuss with my veterinarian before giving ketoconazole: Do not give ketoconazole if your pet is being given astemizole (Hismanal), cisapride (Propulsid) or triazolam (Halcion). Dangerous or life threatening events may occur. Do not use this medication in animals allergic to it or similar medications. Tell your veterinarian if your pet has liver disease, or if your pet is being given antacids, stomach acid reducers or stomach ulcer medications. Tell your veterinarian if your pet is pregnant or lactating or if you plan to breed your pet.

How should this medication be given: Give ketoconazole exactly as directed by your veterinarian. If you do not understand these directions, ask your pharmacist or veterinarian to explain them to you. Ketoconazole should be given with food. Do not give ketoconazole within 2 hours of an antacid. Allow plenty of drinking water for the pet. Blood tests or other medical evaluations may be required by your veterinarian to monitor progress and side effects. Store ketoconazole at room temperature away from heat and moisture. Keep this medication out of the reach of children and other pets.

What happens if I miss giving a dose: Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication unless directed to by your veterinarian.

What happens if I overdose the pet: Contact your veterinarian or veterinary emergency room. Symptoms of ketoconazole overdose may include dizziness, headache, nausea, vomiting, diarrhea, and abdominal pain.

What should I avoid while giving ketoconazole to my pet: Ketoconazole may cause dizziness. Use caution when given with other medicines that may also cause dizziness.

What are the possible side effects of ketoconazole: If any of the following serious side effects occur, stop giving ketoconazole and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing, swelling of the lips, tongue, or face; hives); or liver damage (yellowish eyes, abdominal pain, unusual fatigue, or dark urine). Other less serious side effects may occur. If any of the following side effects occur, continue to give ketoconazole and talk to your veterinarian; nausea, vomiting, or abdominal pain; diarrhea; headache; dizziness; fatigue; itching. Side effects other than those listed in this guide may occur. Talk to your veterinarian about any side effect that seems unusual or that is especially bothersome to the pet.

What other drugs will affect ketoconazole: Do not give ketoconazole if your pet is being given astemizole (Hismanal), cisapride (Propulsid) or triazolam (Halcion). Dangerous or life threatening events may occur. Before giving ketoconazole, tell your veterinarian about any medications you are giving your pet, especially; cyclosporine (Neoral), methylprednisolone (Medrol), antacids, cimetidine (Tagamet), Nizatidine (Axid), famotidine (pepcid), ranitidine (Zantac), omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), digoxin (Lanoxin), warfarin (Coumadin), phenytoin (Dilantin), glipizide (Glucotrol). Drugs other than those listed in this guide may also interact with ketoconazole. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines, including vitamins, minerals, and herbal products.

Where can I get additional information: Your pharmacist as additional information about ketoconazole written for health professionals that you may read.


Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.

Directions:

Ketoconazole is a prescription medication used in dogs and cats to treat various internal and external fungal infections. Ketoconazole is also used to treat Cushing’s disease.
Ketoconazole should be given with food. Allow plenty of water for the pet to drink. Do not give Ketoconazole within 2 hours of antacids.
It is very important that you tell your veterinarian or pharmacist about any other medications your pet is taking.

Tip: Results of treatment may not be seen for 1 or 2 weeks and the duration of treatment may last up to several months. The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Make sure you complete the prescription unless specifically directed by your veterinarian. Even if your pet feels better, the entire treatment plan should be completed to prevent relapse or prevent the development of resistance.
Dosage:
Pet Weight Dosage
Dogs/Cats: All weights Dosage depends on the particular disease being treated
Horses:
Storage: Store this product at room temperature.
Ketoconazole:
Active Ingredient: Amount
Ketoconazole 200 mg
Ketoconazole 3.8 5 12 12
Ketoconazole Secondary yeast and fungal infections are indeed frustrating problems to deal with both for pet and animal guardian. Yeast overgrowths are often secondary to underlying itching and skin allergies, as well as sometimes overuse of oral antibiotics. Guardians and veterinarians will often notice a musty or rotton sock odor often emanating from their pets ears or skin. Sometimes sticky discharge with dark discoloration of the skin can occur. Diagnosis of yeast infection is usually accomplished at a veterinarian's office via exam of the discharge under the microscope. This often forgotten inexpensive diagnostic technique, often leads to misuse of antibiotics in our pets, as well as a worsening of the skin problem. Once diagnosed, I have found ketoconazole a very safe and effective product in helping kill yeast overgrowth on the skin and ears, often leading to much symptomatic relief. However it is important for veterinarians to address the underlying causes of yeast overgrowth such as inhalent/contact allergies, food allergies or hormonal disorders, or the problem will recur. While in the veterinary literature there is caution with this drug in causing liver problems, I have not found this to be much of a problem in my experience and opinion. The biggest side effect I have seen in some pets is vomiting or diarrhea, which I find is usually minimized by giving with small amounts of food. This drug is also often prescribed by veterinarians in allergic dogs who are also prescribed the expensive allergy drug atopica, because it often allows vets to use lower doses of atopica to help control allergic skin symptoms. As for its other use, I have not found ketoconazole helpful in managing dogs with Cushings disease. I give this product an overall rating of a 4 with an ease of use/taste a 4 as well. 08/02/2009
Tobbey has taken it for seven years with atopica. They has relieved his allergy symptoms completely in addition to his diet change. He is very healthy. Joyce 09/13/2014
Severe liver damage can,t get liver emznye back to normal they were ok before ketoconazole. Dog in serious medical trouble 12/29/2011
My Doberman Pinscher was lactating and cleaning her new borns all the time. She develop blisters outside under her mouth and we tried a topical lotion first. It wasn't quite doing the job. Once the puppies got to 5 weeks, we weaned them off her so she could take this medicine prescribed for 21 days. It has done a better job getting rid of the skin problem but she will vomit at least once a day, mostly the early evening dose she would do this. My vet recommended to stop taking them because she was also taking an antibiotic for a different kind of insect bite infection and see if the vomiting will cease. She has recovered from the blisters and the puppies are well worth the job done for a good mom she is. 08/18/2010
Cleared up the skin problem very quickly. 03/09/2010
38 Questions · 43 Answers

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2 weeks, 1 day ago
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Anonymous
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Answer: 
The dose can only be determined by a veterinarian. After an exam and diagnosis, the vet can
prescribe the correct medication along with the proper dose.
1 week, 5 days ago
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Kelly P
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3 weeks, 6 days ago
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Anonymous
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Please contact your veterinarian. Your vet will be able to determine if the ringworm has cleared after a course of antifungal therapy.
3 weeks, 1 day ago
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Stephanie Duesler, Pharm. D, MBA
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How many tablets would I need for a 20 lb
Westie? What would be the dosage ?
10 months ago
by
horsenut
Ont.
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Answer: 
The appropriate dose to treat your pet would depend on different things, for example where the infection is and how severe it may be. Please discuss your concerns with your doctor and bring in your pet to be seen if you think she may need to be examined.
10 months ago
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Cheryl-Pharmacist
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Lasah Apso 20 pounds. 8 years

Has constant biting and licking in groin area.Is on ketoconazole.
Can ampicillin (infection) be given safely with the ketoclonazole?
1 year ago
by
Joanie
Danbury, CT
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Answer: 
Although these two medications may not have drug interactions consult with your veterinarian to see if this medication is appropriate to treat your pet. Both medications do need prescriptions from your
veterinarian and he or she may want you to bring in your pet to be evaluated.
1 year ago
by
Cheryl-Pharmacist
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I am purchasing a six week old Yorkshire Terrier puppy who has a yeast infection on her skin. I am going to take her to the Vet, however, I am doing research on the subject. I see this as a recommended medication several times but a six week old puppy needs liquid. Can I get this in liquid form? Is there anything I can purchase OTC in liquid form for yeast infection of the skin? I am going to get medicated shampoo specified for yeast infection also. Any advise would be greatly appreciated. Except: "do not buy a puppy with a yeast infection". She is a living being and needs help and I want to help her. Wish I could afford to "help" the whole litter, but I am not rich. Have a feeling just this one pup is going to be very pricy. Thanks in advance for your answers.
1 year, 6 months ago
by
Tiffany's Mama
Georgia
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Answer: 
Ketoconazole is available in liquid form that is available in liquid form. A compounding pharmacy will be able to compound the liquid for your pet. A diagnosis from a veterinarian will ensure the safety of the animal you will be adopting. Please consult with your veterinarian regarding any OTC products you intend to purchase.
1 year, 6 months ago
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Lilli Pharmacist
Pompano Beach, FL
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This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
 
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