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Product Info
How to Use
Customer Reviews
Product Info
What is Ketoconazole?

Ketoconazole is used to treat fungal infections. It is also used to treat Cushing's disease. Ketoconazole, available as 200mg scored tablets (sold per tablet), requires a prescription from your veterinarian.


Cats and Dogs

  • Treats various internal and external fungal infections
  • Easy to administer
How it Works:

Ketoconazole is an antifungal medication that blocks the formation of cortisol in the adrenal glands and for that reason is used in the treatment of Cushing's disease.


Ketoconazole can interact with many other drugs. Fully disclose to your veterinarian any medications your pet is taking before giving ketoconazole. Do not use in pregnant or nursing animals.

Brand Name:

Nizoral (Janssen)

Generic Name:

Ketoconazole (keet-ah-cone'-ah-zole)

What should I discuss with my veterinarian before giving ketoconazole:

Do not give ketoconazole if your pet is being given astemizole (Hismanal), cisapride (Propulsid) or triazolam (Halcion). Dangerous or life threatening events may occur. Do not use this medication in animals allergic to it or similar medications. Tell your veterinarian if your pet has liver disease, or if your pet is being given antacids, stomach acid reducers or stomach ulcer medications. Tell your veterinarian if your pet is pregnant or lactating or if you plan to breed your pet.

What is the most important information I should know about ketoconazole:

Do not give this medication if your pet is taking astemizole (Hismanal), cisapride (Propulsid) or triazolam (Halcion). Combined with these drugs, ketoconazole could cause serious, even fatal side effects. In rare cases, ketoconazole can cause severe liver damage. Notify your veterinarian immediately if your pet develops nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, yellow eyes, itching, or dark urine. These symptoms may be early signs of liver damage.

How should this medication be given:

Give ketoconazole exactly as directed by your veterinarian. If you do not understand these directions, ask your pharmacist or veterinarian to explain them to you. Ketoconazole should be given with food. Do not give ketoconazole within 2 hours of an antacid. Allow plenty of drinking water for the pet. Blood tests or other medical evaluations may be required by your veterinarian to monitor progress and side effects. Store ketoconazole at room temperature away from heat and moisture. Keep this medication out of the reach of children and other pets.

What happens if I miss giving a dose:

Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication unless directed to by your veterinarian.

What should I avoid while giving ketoconazole to my pet:

Ketoconazole may cause dizziness. Use caution when given with other medicines that may also cause dizziness.

What are the possible side effects of ketoconazole:

If any of the following serious side effects occur, stop giving ketoconazole and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing, swelling of the lips, tongue, or face; hives); or liver damage (yellowish eyes, abdominal pain, unusual fatigue, or dark urine). Other less serious side effects may occur. If any of the following side effects occur, continue to give ketoconazole and talk to your veterinarian; nausea, vomiting, or abdominal pain; diarrhea; headache; dizziness; fatigue; itching. Side effects other than those listed in this guide may occur. Talk to your veterinarian about any side effect that seems unusual or that is especially bothersome to the pet.

What other drugs will affect ketoconazole:

Do not give ketoconazole if your pet is being given astemizole (Hismanal), cisapride (Propulsid) or triazolam (Halcion). Dangerous or life threatening events may occur. Before giving ketoconazole, tell your veterinarian about any medications you are giving your pet, especially; cyclosporine (Neoral), methylprednisolone (Medrol), antacids, cimetidine (Tagamet), Nizatidine (Axid), famotidine (pepcid), ranitidine (Zantac), omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), digoxin (Lanoxin), warfarin (Coumadin), phenytoin (Dilantin), glipizide (Glucotrol). Drugs other than those listed in this guide may also interact with ketoconazole. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines, including vitamins, minerals, and herbal products.

How to Use
  • Ketoconazole is a prescription medication used in dogs and cats to treat various internal and external fungal infections. Ketoconazole is also used to treat Cushing's disease.
  • Ketoconazole should be given with food. Allow plenty of water for the pet to drink. Do not give Ketoconazole within 2 hours of antacids.
  • It is very important that you tell your veterinarian or pharmacist about any other medications your pet is taking.

Results of treatment may not be seen for 1 or 2 weeks and the duration of treatment may last up to several months. The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Make sure you complete the prescription unless specifically directed by your veterinarian. Even if your pet feels better, the entire treatment plan should be completed to prevent relapse or prevent the development of resistance.

All weights
Dosage depends on the particular disease being treated
Do not use!

Store this product at room temperature.

Active Ingredient:
200 mg
Customer Reviews
Ketoconazole is rated 4.0 out of 5 by 15.
Rated 5 out of 5 by from Allergies I have used this for my Zoe and it worked so good for her.
Date published: 2016-03-22
Rated 5 out of 5 by from Definitely helped with cushings When my Charlie was diagnosed with Cushings disease I was worried because he'd lost weight and hair in patches here and there. After taking ketoconazole he's back to his normal weight and his hair is coming back and the dandruff is gone. He seems like he feels better too!
Date published: 2014-11-19
Rated 5 out of 5 by from Wonderful! My 60 lb shepherd mix was on 100 mg of Atopica daily and would still get occasional ear infections. Vet changed to Ketoconazole (3/4 tablet) and 50 mg Atopica and it made a huge difference. I am now giving this dosage every other day and will try to go to every three days. The Ketoconazole has been a life saver.
Date published: 2014-11-15
Rated 5 out of 5 by from Tobbey has taken it for seven years with atopica. They has relieved his allergy symptoms completely in addition to his diet change. He is very healthy. Joyce
Date published: 2014-09-13
Rated 1 out of 5 by from Severe liver damage can,t get liver emznye back to normal they were ok before ketoconazole. Dog in serious medical trouble
Date published: 2011-12-30
Rated 4 out of 5 by from My Doberman Pinscher was lactating and cleaning her new borns all the time. She develop blisters outside under her mouth and we tried a topical lotion first. It wasn't quite doing the job. Once the puppies got to 5 weeks, we weaned them off her so she could take this medicine prescribed for 21 days. It has done a better job getting rid of the skin problem but she will vomit at least once a day, mostly the early evening dose she would do this. My vet recommended to stop taking them because she was also taking an antibiotic for a different kind of insect bite infection and see if the vomiting will cease. She has recovered from the blisters and the puppies are well worth the job done for a good mom she is.
Date published: 2010-08-19
Rated 5 out of 5 by from Cleared up the skin problem very quickly.
Date published: 2010-03-09
Rated 5 out of 5 by from All Over Yeast Infection My lab, Bo, who is now 11, has been battling yeast infections for a couple of years now. A few summers back, after spending most of his time swimming in our pool, Bo became very, very stinky. Like old gym socks. The vet put him on this product and within a few weeks, the infection began to clear and the smell started going away. I use it year round, but reduce the dose down to 1x a week, or not at all in the winter. Because he likes the water so much, and his coat is dense, he is prone to this type of infection, so by summer, I am usually using it 3x's to 4x's a week. Last summer, because I was proactive, he never broke out into an all over body infection and what little there was, never got out of control.
Date published: 2010-01-26
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May I apply Ketoconazole Cream to open wound?

It seems as though my dog was injured by another dog as they were playing. My dog wasn't bitten but she received a laceration on the right cheek(it's a small circle about 3/4 inch in diameter). It is an opened wound. I have Ketoconazole cream 2%. Did I apply to the wound or no?
Asked by: Anonymous
I would recommend that you contact your veterinarian prior to using something on your dogs open wound. Your veterinarian may want to examine your pet to see if antibiotics are necessary. Ketoconazole is an antifungal and may not be appropriate.
Answered by: Cheryl-Pharmacist
Date published: 2015-04-13

Anal Furunculosis

I found on a web page a study on anal furunculosis which my dog has had for 2 years he is miserable the study which mentioned ketoconazole as a must when using atopica for treatment why can i not buy this drug in the UK and what are your recommendations for anal furunculosis.America always seems to be way ahead on treatments that work.
Asked by: Fee
Your veterinarian will determine the appropriate treatment regimen for you particular pet. Similarly, information regarding drug availability in your area may also be obtained from your veterinarian.
Answered by: Lisa M
Date published: 2015-04-07

If my Cat has ringworm? How many should I give per day?

Asked by: Anonymous
The dose can only be determined by a veterinarian. After an exam and diagnosis, the vet can prescribe the correct medication along with the proper dose.
Answered by: Kelly P
Date published: 2014-10-07

How long will a dog taking this for ringworm be contagious?

Asked by: Anonymous
Please contact your veterinarian. Your vet will be able to determine if the ringworm has cleared after a course of antifungal therapy.
Answered by: Stephanie Duesler, Pharm. D, MBA
Date published: 2014-09-29

How many tablets would I need for a 20 lb westie?

How many tablets would I need for a 20 lb Westie? What would be the dosage ?
Asked by: horsenut
The appropriate dose to treat your pet would depend on different things, for example where the infection is and how severe it may be. Please discuss your concerns with your doctor and bring in your pet to be seen if you think she may need to be examined.
Answered by: Cheryl-Pharmacist
Date published: 2013-12-03

can ketoconazole be safely given with ampicillin?

Lasah Apso 20 pounds. 8 years Has constant biting and licking in groin area.Is on ketoconazole. Can ampicillin (infection) be given safely with the ketoclonazole?
Asked by: Joanie
Although these two medications may not have drug interactions consult with your veterinarian to see if this medication is appropriate to treat your pet. Both medications do need prescriptions from your veterinarian and he or she may want you to bring in your pet to be evaluated.
Answered by: Cheryl-Pharmacist
Date published: 2013-09-23

Can I get a liquid form for puppy

I am purchasing a six week old Yorkshire Terrier puppy who has a yeast infection on her skin. I am going to take her to the Vet, however, I am doing research on the subject. I see this as a recommended medication several times but a six week old puppy needs liquid. Can I get this in liquid form? Is there anything I can purchase OTC in liquid form for yeast infection of the skin? I am going to get medicated shampoo specified for yeast infection also. Any advise would be greatly appreciated. Except: "do not buy a puppy with a yeast infection". She is a living being and needs help and I want to help her. Wish I could afford to "help" the whole litter, but I am not rich. Have a feeling just this one pup is going to be very pricy. Thanks in advance for your answers.
Asked by: Tiffany's Mama
Ketoconazole is available in liquid form that is available in liquid form. A compounding pharmacy will be able to compound the liquid for your pet. A diagnosis from a veterinarian will ensure the safety of the animal you will be adopting. Please consult with your veterinarian regarding any OTC products you intend to purchase.
Answered by: Lilli Pharmacist
Date published: 2013-04-02

Is Ketoconazole safe with Atopica?

Asked by: Diane
Yes, they are commonly used together.
Answered by: Kelly P
Date published: 2013-01-03
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