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K9 Advantix II

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Product Info
How to Use
Ingredients
Customer Reviews
Q&A
Product Info
What is K9 Advantix II?

K9 Advantix II is a monthly preventative for dogs that offers comprehensive protection against ticks, fleas, mosquitoes, biting flies, and chewing lice. K9 Advantix II is a top veterinarian-recommended brand because it repels and kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks). K9 Advantix II kills 98-100 percent of fleas within 12 hours and continues working for one month to prevent infestations. Fleas and ticks are killed on contact with a treated dog, which means that fleas don't have to bite and ticks don't have to attach to die. This helps prevent transmission of flea-borne and tick-borne diseases such as tapeworms, Lyme disease, tick paralysis, ehrlichia, and Rocky Mountain spotted fever. Killing fleas before they bite may also help prevent skin allergies caused by flea saliva. As well, K9 Advantix II repels mosquitoes before they bite, which may help prevent transmission of heartworms. K9 Advantix II protects your pet before parasites have a chance to bite, not after.

For:

Dogs and Puppies (only over 4 lbs and 7 weeks of age or older)

Benefits:
  • Repels and kills disease-carrying fleas, ticks, and mosquitoes before they bite
  • Kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks)
  • Kills 98-100 percent of adult fleas within 12 hours
  • Ends flea life cycle by preventing flea offspring (eggs, pupae, and larvae) from maturing into adult fleas
  • Repels biting flies and kills chewing lice
  • Provides one month of protection against ticks, fleas, mosquitoes, biting flies
  • Waterproof - continues working even after your dog becomes wet
How it works:

K9 Advantix II combines imidacloprid and permethrin to repel and kill fleas, ticks, and mosquitoes. Both ingredients work on contact, attacking parasite nerve cells at different sites. Together these ingredients overwhelm the nervous system killing the parasite. Pyriproxyfen is an insect growth regulator. K9 Advantix II topical solution also repels biting flies and kills lice.

Cautions:

DO NOT USE ON CATS. Cats cannot metabolize the ingredients used in this product. Cats must be separated from dogs during treatment. Do not allow your cat to come in contact with a treated dog for 24 hours. Some small and medium dogs may have an adverse skin reaction.

Brand Name:

K9 Advantix II (Bayer)

Active Ingredient(s):

Imidacloprid (8.8%), Permethrin (44.0%), Pyriproxyfen (0.44%), Other ingredients (46.76%)

What is this product used for:

K9 Advantix II is for use on dogs and puppies 4 lbs or more and 7 weeks of age or older only. It is used for the topical prevention and treatment of ticks, fleas, mosquitoes, biting flies, and chewing lice on dogs. Repels and kills ticks including deer ticks (the major carrier of Lyme disease), American dog ticks, Brown dog ticks and lone star ticks. K9 Advantix II repels and kills all life stages of fleas, repels and kills mosquitoes, kills chewing lice, and repels biting flies.

Availability:

K9 Advantix II is a non-prescription (OTC) product available as 0.014 fl oz (0.4 ml) applicators for dogs 4-10 lbs (Green), 0.034 fl oz (1.0 ml) applicators for dogs 11-20 lbs (Teal), 0.084 fl oz (2.5 ml) applicators for dogs 21-55 lbs (Red), and 0.135 fl oz (4.0 ml) applicators for dogs over 55 lbs (Blue).

How this product should be used:

For use only on dogs. Do not use on cats or on other animals. Have the dog standing for easy application. Part the hair on the dog's back, between the shoulder blades, until the skin is visible. For dogs up to 20 lbs, apply the entire contents of the applicator tube to 2 or 3 spots on the top of the back from the shoulder to the base of the tail. For dogs 21 lbs and over, apply the entire contents of the applicator tube to 4 or 6 spots on the top of the back from the shoulder to the base of the tail. If the household has cats or other animals, separate from the treated dog for 24 hours.

What are the side effects:

Individual sensitivities, while rare, may occur after using any pesticide product for pets. A small percentage of dogs have had adverse reactions to K9 Advantix II. A sensation of burning, tingling, itching, redness or numbness of the skin may occur after topical application. This sensation usually begins 1-2 hours after application. In addition, reactions have occurred in cats that have been exposed to a medicated dog. That is why it is important to separate your cat from a medicated dog for 24 hours. Bayer, the manufacturer of K9 Advantix II, indicates that some of these symptoms will dissipate within 48 hours; however, if your pet is experiencing adverse reactions, please complete the following steps:

  • Stop applying the medication
  • Wash your dog with a detergent based soap (Dawn or Palmolive dish detergents work best). Do not scrub the affected area, as this may cause more skin irritation. Please note: This process is applicable for both dogs and cats.
  • Call your veterinarian
  • Call Bayer Emergency Support Line at 1-800-422-9874. Let Bayer know your dog is having an adverse reaction to K9 Advantix by calling 1-800-422-9874. This line is staffed 24 hours a day, 7 days a week.
What special precautions are there:

This product is for external use only on dogs and puppies 4 lbs or more and 7 weeks or older. Consult a veterinarian before using on medicated animals and debilitated, aged, pregnant or nursing animals. Do not get this product in dog's eyes or mouth. Do not use this product on animals other than dogs. In households with cats, separate the treated dog for about 24 hours. Due to their unique physiology and inability to metabolize certain compounds, this product must not be used on cats. If applied to a cat, or ingested by a cat which actively grooms a recently treated dog, this product may have serious harmful effects. If this occurs, contact your veterinarian immediately. It is important to apply this product no more than once a month and to use the correct strength for the weight of the dog. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have patient sip water. Do not induce vomiting unless advised to and the patient is conscious. This product can cause eye irritation. Flush eyes with plenty of water. Call a physician if irritation persists. Avoid contact with skin, eyes or clothing. Wash thoroughly with soap and water after handling.

In the event of overdose:

Contact your veterinarian or veterinary emergency room.

How should I store this product:

Store this product in a cool, dry place. Do not refrigerate. Store in the original container only. Do not reuse original container. If the container is empty place in trash or offer for recycling if available. If the container is partially filled, call for disposal instructions. Never place unused product down any indoor or outdoor drain.

How to Use
Directions:
  • Use only on dogs over 4 lbs and over 7 weeks of age. Do not use on cats or on other animals.
  • Your dog should be standing for easy application.
  • The entire contents of K9 Advantix II tube should be applied evenly to the top of the back from the shoulder to the base of the tail.
  • At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin.
  • Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of your dog.
  • For dogs up to 20 lbs, apply the entire contents of the applicator tube to 2 or 3 spots on the top of the back from the shoulder to the base of the tail.
  • For dogs 21 lbs and over, apply the entire contents of the applicator tube to 4 or 6 spots on the top of the back from the shoulder to the base of the tail.
  • Use only one applicator per treatment.
Tip:

In households with cats, separate the treated dog for 24 hours until the product is thoroughly dry. Visit K9 Advantix II Adverse Reactions if your pet has been experiencing adverse reactions to K9 Advantix II.

Dosage:
Dogs/Puppies:(7 weeks of age and older)
Weight
Dosage
1-3 lbs
Do not use.
4-10 lbs
Apply contents of 1 applicator once a month (Green Box)
11-20 lbs
Apply contents of 1 applicator once a month (Teal Box)
21-55 lbs
Apply contents of 1 applicator once a month (Red Box)
Over 55 lbs
Apply contents of 1 applicator once a month (Blue Box)
Cats:
Do not use!
Horses:
Do not use!
Storage:

Should be stored in a cool dry place. Do not refrigerate.

Ingredients
K9 Advantix II for Dogs 4-10 lbs (Small Dog - Green Box) (0.4 mL):
Active Ingredients (per applicator tube)
% By Weight
Imidacloprid
8.80%
Permethrin*
44.0%
Pyriproxyfen
0.44%
Other Ingredients (not specified)
46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 11-20 lbs (Medium Dog - Teal Box) (1.0 mL):
Active Ingredients (per applicator tube)
% By Weight
Imidacloprid
8.80%
Permethrin*
44.0%
Pyriproxyfen
0.44%
Other Ingredients (not specified)
46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 21-55 lbs (Large Dog - Red Box) (2.5 mL):
Active Ingredients (per applicator tube)
% By Weight
Imidacloprid
8.80%
Permethrin*
44.0%
Pyriproxyfen
0.44%
Other Ingredients (not specified)
46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs over 55 lbs (Extra Large Dog - Blue Box) (4.0 mL):
Active Ingredients (per applicator tube)
% By Weight
Imidacloprid
8.80%
Permethrin*
44.0%
Pyriproxyfen
0.44%
Other Ingredients (not specified)
46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
Customer Reviews
K9 Advantix II is rated 3.7108 out of 5 by 3,683.
Rated 5 out of 5 by from Dependable Bella is in the river several times a week and runs all over 26 acres of land. K9 Advantix keeps her & our house bug free!
Date published: 2016-04-26
Rated 5 out of 5 by from Great product I have six labs and use this because it works so well, especially for ticks. I also like the fact it repels mosquitoes and of course works well against fleas.
Date published: 2016-04-26
Rated 5 out of 5 by from Excellent Product I live in the woods with lots of deer and animals around. I feel Kaiya is safe from all the nasty critters that could harm her when using K9 Advantix II. Best defense I have used!!!
Date published: 2016-04-24
Rated 5 out of 5 by from Great Product My 90lb lab was previously on Frontline until he became flea infested even while on the medication. After a month of no improvement I decided to try a different product. The results were almost immediate and I could see the fleas dying and falling off of him. Something that never happened while on frontline. I've kept him on advantix since then and he's never gotten fleas again.
Date published: 2016-04-19
Rated 1 out of 5 by from Does not work I put this on my dog Friday, it's Tuesday and I just pulled a tick off of him. Clearly this product does not work as it claims to.
Date published: 2016-04-19
Rated 5 out of 5 by from Great product that works fast! Works great for my German shep/lab mixes. Killed fleas right away and did not cause any irritation to my dogs' sensitive skin. I am very satisfied with this product!
Date published: 2016-04-17
Rated 5 out of 5 by from tried a less expensive brand but came back ASAP My husband researched the ingredients in all the topical flea products and he bought a less expensive brand from Walmart. We were quickly disappointed in the choice he made. The ingredients were the same except for the repellent. We used up the other brand and went back to K9 advantix II. It's more expensive, but it is worth every penny. K9 will repel and eventually eradicate the fleas in your yard. I can't speak for ticks because our problem stems mainly with fleas. My advice is to spend the extra money and go with K9 advantix II, you'll be glad you did.
Date published: 2016-04-16
Rated 5 out of 5 by from Excellent Product ! Excellent products, prices, and customer service.
Date published: 2016-04-15
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Q&A

I have a 10 week old Chihuahua and he is covered in fleas and weighs less then a pound or right at a pound. Is there a dosage safe for him?

Asked by: Susan
The K9 Advantix II is safe for dogs and puppies (only over 4 lbs and 7 weeks of age or older). This product may be too strong for your furry baby. You may want to consult with your vet to see what other options are available. We do offer the Revolution for puppies and kittens between 0-5 lbs. The Revolution requires a prescription from your veterinarian. Please see the link below to view the revolution. http://www.1800petmeds.com/Revolution-prod10265.html?Ntt=revolution
Answered by: Cherley Petmeds Pro
Date published: 2016-04-30

What if I missed an application and found a tick on my dog? I saw a video that if you place a drop near the tick it will fall off quickly so no tweezers are needed?

Asked by: AlanB
K9 Advantix II kills 98-100 percent of fleas within 12 hours and continues working for one month to prevent infestations. Fleas and ticks are killed on contact with a treated dog, which means that fleas don't have to bite and ticks don't have to attach to die. As a licensed pharmacy, we cannot recommend placing a drop near a tick. Here are the dosing instructions below: - The entire contents of K9 Advantix II tube should be applied evenly to the top of the back from the shoulder to the base of the tail. - At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. - Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of your dog. - For dogs up to 20 lbs, apply the entire contents of the applicator tube to 2 or 3 spots on the top of the back from the shoulder to the base of the tail. - For dogs 21 lbs and over, apply the entire contents of the applicator tube to 4 or 6 spots on the top of the back from the shoulder to the base of the tail. Use only one applicator per treatment.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-30

I have 1 left over, un-opended monthly application of K9 Advantix II from 2011.  Can I still use it or should I throw it out? What's the shelf life of this product?

Asked by: GailE
Yes, the K9 Advantix II does not expire.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-22

I'm getting a puppy whose weight will fluctuate in the beginning. Can i use multiple tubes in combination if the puppy moves to the next weight range?

Asked by: ercook3
Since your furry baby's weight will fluctuate in the beginning, you may want to purchase a couple of single doses within your furry baby's current weight from your veterinarian until your furry baby is full grown. We do not recommend using multiple tubes. This prevents over or under medicating your furry baby.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-18

Is this product from china.

Asked by: Erica
K9 Advantix II is made in Germany.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-22

My dog weighs about 55 lbs, might go a pound or 2 over or under. Should I buy the 21-55 lb or the 55 lb+?

Asked by: allison
The 55 lbs and over is recommended for dogs over 55 lbs even if it is a pound or two over 55 lbs. However, if your pet fluctuates and gets under 55 lbs more than over 55 lbs, it is recommended to stay with the 21-55 lbs dose.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-05

I have boxers even putting the tube in 6 spots on them I still have some liquid in the tube is this normal? If I add the full tube it will run all over their backs.

Asked by: Jessica2
For dogs 21 lbs and over, apply the entire contents of the applicator tube to 4 or 6 spots on the top of the back from the shoulder to the base of the tail. You may want to go down deep into the skin when applying drops or trying 7 or 8 spots instead of 6.
Answered by: Cherley Petmeds Pro
Date published: 2016-03-23

How many days do I need to wait after I apply Advantix to give my furry babies a bath? 

Asked by: Donna
24-48 Hours.
Answered by: Cherley Petmeds Pro
Date published: 2016-04-03
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